Antibodies
Showing 151–300 of 2318 results
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Immunogen: Human recombinant protein • Host: Rabbit • Species Reactivity: (+) Human asprosin • Applications: IP, WB
Brand:CaymanSKU:23857- 300 µgAvailable on backorder
Immunogen: Human recombinant protein • Host: Rabbit • Species Reactivity: (+) Human asprosin • Applications: IP, WB
Brand:CaymanSKU:23857- 300 µg
Antigen: synthetic phosphopeptide corresponding to amino acid residues surrounding phospho-Ser490,498 of human ATF2 · Host: rabbit · Cross-reactivity: (+) human ATF2; expected to react with rat ATF2 · Applications: WB and IHC (frozen sections) • ATF2 binds to both AP-1 and CRE DNA response elements and is a member of the ATF/CREB family of leucine zipper proteins. It has been implicated in the transcriptional regulation of a number of genes including cytokines, cell cycle control, and apoptosis.
Brand:CaymanSKU:10009410- 100 µlAvailable on backorder
Antigen: synthetic phosphopeptide corresponding to amino acid residues surrounding phospho-Ser490,498 of human ATF2 · Host: rabbit · Cross-reactivity: (+) human ATF2; expected to react with rat ATF2 · Applications: WB and IHC (frozen sections) • ATF2 binds to both AP-1 and CRE DNA response elements and is a member of the ATF/CREB family of leucine zipper proteins. It has been implicated in the transcriptional regulation of a number of genes including cytokines, cell cycle control, and apoptosis.
Brand:CaymanSKU:10009410- 100 µl
Brand:CaymanSKU:32756- 100 µlAvailable on backorder
Brand:CaymanSKU:32756- 100 µl
Immunogen: Full-length human recombinant ATG4B protein • Host: Mouse • Species Reactivity: Human • Cross Reactivity: (-)-ATG8 • Applications: ELISA, IHC, IP, and WB • MW = ~44 kDa
Brand:CaymanSKU:25963- 100 µgAvailable on backorder
Immunogen: Full-length human recombinant ATG4B protein • Host: Mouse • Species Reactivity: Human • Cross Reactivity: (-)-ATG8 • Applications: ELISA, IHC, IP, and WB • MW = ~44 kDa
Brand:CaymanSKU:25963- 100 µg
Immunogen: Full-length human recombinant ATG5 protein • Host: Mouse • Species Reactivity: (+) Human • Cross Reactivity: (-) ATG8 • Applications: ELISA, IF
Brand:CaymanSKU:28812- 100 µgAvailable on backorder
Immunogen: Full-length human recombinant ATG5 protein • Host: Mouse • Species Reactivity: (+) Human • Cross Reactivity: (-) ATG8 • Applications: ELISA, IF
Brand:CaymanSKU:28812- 100 µg
Immunogen: Full-length human recombinant ATG5 protein • Host: Mouse • Species Reactivity: (+) Human; other species not tested • Cross Reactivity: (-) ATG8 • Applications: ELISA, IHC, and WB • MW: ~56 kDa for the ATG5-ATG12 complex
Brand:CaymanSKU:26671- 100 µgAvailable on backorder
Immunogen: Full-length human recombinant ATG5 protein • Host: Mouse • Species Reactivity: (+) Human; other species not tested • Cross Reactivity: (-) ATG8 • Applications: ELISA, IHC, and WB • MW: ~56 kDa for the ATG5-ATG12 complex
Brand:CaymanSKU:26671- 100 µg
Immunogen: Peptide corresponding to B-RAFV600E • Host: Rabbit • Species Reactivity: (+) Human • Cross Reactivity: (+) B-RAFV600E; (-) Wild-type B-RAF • Applications: ELISA, ICC, IHC, WB
Brand:CaymanSKU:32188- 100 µgAvailable on backorder
Immunogen: Peptide corresponding to B-RAFV600E • Host: Rabbit • Species Reactivity: (+) Human • Cross Reactivity: (+) B-RAFV600E; (-) Wild-type B-RAF • Applications: ELISA, ICC, IHC, WB
Brand:CaymanSKU:32188- 100 µg
Immunogen: Full-length recombinant human Beclin 1 • Host: Mouse • Species Reactivity: (+) Human • Applications: WB and ELISA • MW = 51.9 kDa
Brand:CaymanSKU:25964- 100 µgAvailable on backorder
Immunogen: Full-length recombinant human Beclin 1 • Host: Mouse • Species Reactivity: (+) Human • Applications: WB and ELISA • MW = 51.9 kDa
Brand:CaymanSKU:25964- 100 µg Antigen: internal central human Bim amino acids · Host: rabbit · Cross Reactivity: (+) human, mouse, and rat Bim/BOD (IN) · Applications: IHC and WB • Bim/BOD interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, -xL, and -w and induces apoptosis.
Brand:CaymanSKU:10011385- 100 µg Antigen: internal central human Bim amino acids · Host: rabbit · Cross Reactivity: (+) human, mouse, and rat Bim/BOD (IN) · Applications: IHC and WB • Bim/BOD interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, -xL, and -w and induces apoptosis.
Brand:CaymanSKU:10011385- 100 µgAvailable on backorder
Antigen: internal central human Bim amino acids · Host: rabbit · Cross Reactivity: (+) human, mouse, and rat Bim/BOD (IN) · Applications: IHC and WB • Bim/BOD interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, -xL, and -w and induces apoptosis.
Brand:CaymanSKU:10011385- 25 µg Antigen: internal central human Bim amino acids · Host: rabbit · Cross Reactivity: (+) human, mouse, and rat Bim/BOD (IN) · Applications: IHC and WB • Bim/BOD interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, -xL, and -w and induces apoptosis.
Brand:CaymanSKU:10011385- 25 µgAvailable on backorder
Immunogen: HeLa cells transfected with human BLT1 • Clone designation: 7B1 • Host: Mouse • Cross-Reactivity: (+) BLT1; (−) BLT2, CysLT1, and CysLT2 receptors • Species Reactivity: (+) Human • Isotype: IgG2a • Application(s): FC, IF, and IHC of frozen sections • The human BLT1 receptor is a GPCR that mediates the proinflammatory effects of leukotriene B4 (LTB4). Northern blotting reveals that the BLT1 receptor is highly expressed in leukocytes, U937 cells, and to a much lower extent in spleen and thymus.
Brand:CaymanSKU:120111- 1 eaAvailable on backorder
Immunogen: HeLa cells transfected with human BLT1 • Clone designation: 7B1 • Host: Mouse • Cross-Reactivity: (+) BLT1; (−) BLT2, CysLT1, and CysLT2 receptors • Species Reactivity: (+) Human • Isotype: IgG2a • Application(s): FC, IF, and IHC of frozen sections • The human BLT1 receptor is a GPCR that mediates the proinflammatory effects of leukotriene B4 (LTB4). Northern blotting reveals that the BLT1 receptor is highly expressed in leukocytes, U937 cells, and to a much lower extent in spleen and thymus.
Brand:CaymanSKU:120111- 1 ea
Immunogen: Synthetic peptide from the C-terminal region of human BLT1 • Host: Rabbit • Cross Reactivity: (-) BLT2, CysLT1, and CysLT2 Receptors 1 • Species Reactivity (+) human, bovine, and mouse BLT1 receptor • Application(s): FC, ICC, IHC, and WB • The human BLT1 receptor is a GPCR that mediates the proinflammatory effects of leukotriene B4 (LTB4). Northern blotting reveals that the BLT1 receptor is highly expressed in leukocytes, U937 cells, and to a much lower extent in spleen and thymus.
Brand:CaymanSKU:120114- 500 µlAvailable on backorder
Immunogen: Synthetic peptide from the C-terminal region of human BLT1 • Host: Rabbit • Cross Reactivity: (-) BLT2, CysLT1, and CysLT2 Receptors 1 • Species Reactivity (+) human, bovine, and mouse BLT1 receptor • Application(s): FC, ICC, IHC, and WB • The human BLT1 receptor is a GPCR that mediates the proinflammatory effects of leukotriene B4 (LTB4). Northern blotting reveals that the BLT1 receptor is highly expressed in leukocytes, U937 cells, and to a much lower extent in spleen and thymus.
Brand:CaymanSKU:120114- 500 µl
Immunogen: peptide from the C-terminal region of human BLT2 • Host: Rabbit • Species Reactivity: (+) Human and mouse • Application(s): WB
Brand:CaymanSKU:120124- 1 eaAvailable on backorder
Immunogen: peptide from the C-terminal region of human BLT2 • Host: Rabbit • Species Reactivity: (+) Human and mouse • Application(s): WB
Brand:CaymanSKU:120124- 1 ea
Antigen: synthetic peptide from human Bnc 1 within the region of amino acids 330-380 • Host: rabbit • Cross-reactivity: (+) chimpanzee, human, and monkey Bnc 1 • Application(s): WB • Bnc 1 is a 994 amino acid transcription factor specific for squamous epithelium and for the constituent keratinocytes at a stage either prior to or at the very beginning of terminal differentiation. It is a soluble protein that can shuttle between the nucleus and the cytoplasm. Phosphorylation on Ser537 and Ser541 leads to its cytoplasmic localization.
Brand:CaymanSKU:13502- 1 eaAvailable on backorder
Antigen: synthetic peptide from human Bnc 1 within the region of amino acids 330-380 • Host: rabbit • Cross-reactivity: (+) chimpanzee, human, and monkey Bnc 1 • Application(s): WB • Bnc 1 is a 994 amino acid transcription factor specific for squamous epithelium and for the constituent keratinocytes at a stage either prior to or at the very beginning of terminal differentiation. It is a soluble protein that can shuttle between the nucleus and the cytoplasm. Phosphorylation on Ser537 and Ser541 leads to its cytoplasmic localization.
Brand:CaymanSKU:13502- 1 ea
Recombinant human full-length c-Fos • Host: Mouse • Species Reactivity: (+) Human, Bovine, Mouse, Rat • Applications: ICC, IHC, WB • MW = ~50 kDa
Brand:CaymanSKU:29262- 100 µl Recombinant human full-length c-Fos • Host: Mouse • Species Reactivity: (+) Human, Bovine, Mouse, Rat • Applications: ICC, IHC, WB • MW = ~50 kDa
Brand:CaymanSKU:29262- 100 µlAvailable on backorder
Immunogen: Peptide from the C-terminal region of human calponin-1 • Host: Rabbit • Species Reactivity: (+) Human, mouse • Cross Reactivity: (+) Calponin-1 • Applications: ICC, WB
Brand:CaymanSKU:32207- 100 µlAvailable on backorder
Immunogen: Peptide from the C-terminal region of human calponin-1 • Host: Rabbit • Species Reactivity: (+) Human, mouse • Cross Reactivity: (+) Calponin-1 • Applications: ICC, WB
Brand:CaymanSKU:32207- 100 µl
Immunogen: Peptide from the N-terminal region of human calretinin • Host: Rabbit • Species Reactivity: (+) Human • Cross Reactivity: (+) Calretinin • Applications: IHC, WB
Brand:CaymanSKU:32262- 100 µlAvailable on backorder
Immunogen: Peptide from the N-terminal region of human calretinin • Host: Rabbit • Species Reactivity: (+) Human • Cross Reactivity: (+) Calretinin • Applications: IHC, WB
Brand:CaymanSKU:32262- 100 µl
Immunogen: Phosphopeptide corresponding to amino acid residues surrounding phospho-Thr286 of rat CaM Kinase II • Host: Rabbit • Species Reactivity: (+) Human, Mouse, Rabbit, Rat • Applications: IHC and WB • MW = ~50 and 60 kDa for CaMKIIα phospho-Thr286 and CaMKIIβ phospho-Thr286, respectively
Brand:CaymanSKU:29253- 100 µl Immunogen: Phosphopeptide corresponding to amino acid residues surrounding phospho-Thr286 of rat CaM Kinase II • Host: Rabbit • Species Reactivity: (+) Human, Mouse, Rabbit, Rat • Applications: IHC and WB • MW = ~50 and 60 kDa for CaMKIIα phospho-Thr286 and CaMKIIβ phospho-Thr286, respectively
Brand:CaymanSKU:29253- 100 µlAvailable on backorder
Antigen: mouse recombinant CaMKII • Host: mouse, clone 22B1 • Isotype: IgG1 • Cross Reactivity: (+) rat CaMKII • Application(s): ELISA, IF, IP, and WB • CaMKII functions in neural synaptic stimulation and T-cell receptor signaling. The binding of Ca2+/calmodulin to its regulatory domain releases its auto inhibitory effect and activates the kinase. This kinase activation results in autophosphorylation at Thr286. PP1 dephosphorylates phospho-CaMKII at Thr286 and PKA prevents this dephosphorylation.
Brand:CaymanSKU:10011438- 100 µg Antigen: mouse recombinant CaMKII • Host: mouse, clone 22B1 • Isotype: IgG1 • Cross Reactivity: (+) rat CaMKII • Application(s): ELISA, IF, IP, and WB • CaMKII functions in neural synaptic stimulation and T-cell receptor signaling. The binding of Ca2+/calmodulin to its regulatory domain releases its auto inhibitory effect and activates the kinase. This kinase activation results in autophosphorylation at Thr286. PP1 dephosphorylates phospho-CaMKII at Thr286 and PKA prevents this dephosphorylation.
Brand:CaymanSKU:10011438- 100 µgAvailable on backorder
Antigen: mouse recombinant CaMKII • Host: mouse, clone 22B1 • Isotype: IgG1 • Cross Reactivity: (+) rat CaMKII • Application(s): ELISA, IF, IP, and WB • CaMKII functions in neural synaptic stimulation and T-cell receptor signaling. The binding of Ca2+/calmodulin to its regulatory domain releases its auto inhibitory effect and activates the kinase. This kinase activation results in autophosphorylation at Thr286. PP1 dephosphorylates phospho-CaMKII at Thr286 and PKA prevents this dephosphorylation.
Brand:CaymanSKU:10011438- 25 µg Antigen: mouse recombinant CaMKII • Host: mouse, clone 22B1 • Isotype: IgG1 • Cross Reactivity: (+) rat CaMKII • Application(s): ELISA, IF, IP, and WB • CaMKII functions in neural synaptic stimulation and T-cell receptor signaling. The binding of Ca2+/calmodulin to its regulatory domain releases its auto inhibitory effect and activates the kinase. This kinase activation results in autophosphorylation at Thr286. PP1 dephosphorylates phospho-CaMKII at Thr286 and PKA prevents this dephosphorylation.
Brand:CaymanSKU:10011438- 25 µgAvailable on backorder
Antigen: rat recombinant CaMKII • Host: mouse, clone 6G9 • Isotype: IgG1 • Cross Reactivity: (+) mouse, rat, and bovine CaMKII • Application(s): ELISA, IF, IHC, IP, and WB • CaMKII functions in neural synaptic stimulation and T cell receptor signaling. The binding of Ca2+/calmodulin to its regulatory domain releases its auto inhibitory effect and activates the kinase. This kinase activation results in autophosphorylation at Thr286. PP1 dephosphorylates phospho-CaMKII at Thr286 and PKA prevents this dephosphorylation.
Brand:CaymanSKU:10011437- 100 µg Antigen: rat recombinant CaMKII • Host: mouse, clone 6G9 • Isotype: IgG1 • Cross Reactivity: (+) mouse, rat, and bovine CaMKII • Application(s): ELISA, IF, IHC, IP, and WB • CaMKII functions in neural synaptic stimulation and T cell receptor signaling. The binding of Ca2+/calmodulin to its regulatory domain releases its auto inhibitory effect and activates the kinase. This kinase activation results in autophosphorylation at Thr286. PP1 dephosphorylates phospho-CaMKII at Thr286 and PKA prevents this dephosphorylation.
Brand:CaymanSKU:10011437- 100 µgAvailable on backorder
Antigen: rat recombinant CaMKII • Host: mouse, clone 6G9 • Isotype: IgG1 • Cross Reactivity: (+) mouse, rat, and bovine CaMKII • Application(s): ELISA, IF, IHC, IP, and WB • CaMKII functions in neural synaptic stimulation and T cell receptor signaling. The binding of Ca2+/calmodulin to its regulatory domain releases its auto inhibitory effect and activates the kinase. This kinase activation results in autophosphorylation at Thr286. PP1 dephosphorylates phospho-CaMKII at Thr286 and PKA prevents this dephosphorylation.
Brand:CaymanSKU:10011437- 25 µg Antigen: rat recombinant CaMKII • Host: mouse, clone 6G9 • Isotype: IgG1 • Cross Reactivity: (+) mouse, rat, and bovine CaMKII • Application(s): ELISA, IF, IHC, IP, and WB • CaMKII functions in neural synaptic stimulation and T cell receptor signaling. The binding of Ca2+/calmodulin to its regulatory domain releases its auto inhibitory effect and activates the kinase. This kinase activation results in autophosphorylation at Thr286. PP1 dephosphorylates phospho-CaMKII at Thr286 and PKA prevents this dephosphorylation.
Brand:CaymanSKU:10011437- 25 µgAvailable on backorder
Immunogen: Synthetic peptide surrounding homocitrulline 359 (335 of the mature enzyme) of human A1AT • Host: Rabbit • Species Reactivity: (+) Human • Cross Reactivity: (+) Carbamylated A1AT (-) Non-carbamylated proteins • Application: WB • MW = ~47 kDa
Brand:CaymanSKU:25340- 500 µlAvailable on backorder
Immunogen: Synthetic peptide surrounding homocitrulline 359 (335 of the mature enzyme) of human A1AT • Host: Rabbit • Species Reactivity: (+) Human • Cross Reactivity: (+) Carbamylated A1AT (-) Non-carbamylated proteins • Application: WB • MW = ~47 kDa
Brand:CaymanSKU:25340- 500 µl
Immunogen: Fusion protein of the mouse cardiac troponin I holoprotein • Host: Rabbit • Species Reactivity: (+) Human, Mouse, Rat • Cross Reactivity: none provided • Applications: WB • MW = ~25 kDa
Brand:CaymanSKU:29298- 100 µl Immunogen: Fusion protein of the mouse cardiac troponin I holoprotein • Host: Rabbit • Species Reactivity: (+) Human, Mouse, Rat • Cross Reactivity: none provided • Applications: WB • MW = ~25 kDa
Brand:CaymanSKU:29298- 100 µlAvailable on backorder
Antigen: synthetic peptide corresponding to human caspase-1 within the region of amino acids 371-390 • Host: mouse, clone 14F468 • Isotype: IgG1κ • Cross Reactivity: (+) human and mouse caspase-1 • Application(s): IHC (paraffin-embedded sections) and WB • Caspase-1 is similar to the cell death gene CED-3 of C. elegans and regulates multiple proinflammatory cytokines, including interleukin-1β and interferon-γ-inducing factor.
Brand:CaymanSKU:13907- 1 eaAvailable on backorder
Antigen: synthetic peptide corresponding to human caspase-1 within the region of amino acids 371-390 • Host: mouse, clone 14F468 • Isotype: IgG1κ • Cross Reactivity: (+) human and mouse caspase-1 • Application(s): IHC (paraffin-embedded sections) and WB • Caspase-1 is similar to the cell death gene CED-3 of C. elegans and regulates multiple proinflammatory cytokines, including interleukin-1β and interferon-γ-inducing factor.
Brand:CaymanSKU:13907- 1 ea
Antigen: synthetic peptide corresponding to mouse caspase-14 amino acids 2-18 • Host: mouse • Cross Reactivity: (+) human and mouse caspase-14 • Application(s): FC (intracellular) and WB • Caspase-14 has a conserved active site pentapeptide, QACRG. However, no proteolytic or biological activities have been identified so far.
Brand:CaymanSKU:13916- 1 eaAvailable on backorder
Antigen: synthetic peptide corresponding to mouse caspase-14 amino acids 2-18 • Host: mouse • Cross Reactivity: (+) human and mouse caspase-14 • Application(s): FC (intracellular) and WB • Caspase-14 has a conserved active site pentapeptide, QACRG. However, no proteolytic or biological activities have been identified so far.
Brand:CaymanSKU:13916- 1 ea
Immunogen: Synthetic peptide from an internal region of human caspase-3 • Host: Rabbit • Species Reactivity: (+) Human and mouse; other species not tested • Cross Reactivity: (+) Caspase-2 (proform and active subunits) • Application(s): WB and IHC •
Brand:CaymanSKU:160745- 1 ea Immunogen: Synthetic peptide from an internal region of human caspase-3 • Host: Rabbit • Species Reactivity: (+) Human and mouse; other species not tested • Cross Reactivity: (+) Caspase-2 (proform and active subunits) • Application(s): WB and IHC •
Brand:CaymanSKU:160745- 1 eaAvailable on backorder
Antigen: recombinant full-length human caspase-3 • Host: mouse, clone 31A1067• Isotype: IgG1κ • Cross Reactivity: (+) human, mouse, and rat caspase-3 • Application(s): IHC (frozen and paraffin-embedded sections) and WB • Caspase-3 cleaves the death substrate PARP to a specific 85 kDa form observed during apoptosis and is inhibitable by the CrmA protein. Other caspase-3 substrates include DNA-PK, actin, GAS2, procaspase-6, etc.
Brand:CaymanSKU:13909- 1 eaAvailable on backorder
Antigen: recombinant full-length human caspase-3 • Host: mouse, clone 31A1067• Isotype: IgG1κ • Cross Reactivity: (+) human, mouse, and rat caspase-3 • Application(s): IHC (frozen and paraffin-embedded sections) and WB • Caspase-3 cleaves the death substrate PARP to a specific 85 kDa form observed during apoptosis and is inhibitable by the CrmA protein. Other caspase-3 substrates include DNA-PK, actin, GAS2, procaspase-6, etc.
Brand:CaymanSKU:13909- 1 ea
Antigen: recombinant full-length human caspase-3 • Host: mouse, clone 31A893 • Cross Reactivity: (+) human caspase-3 • Application(s): WB • Caspase-3 cleaves the death substrate PARP to a specific 85 kDa form observed during apoptosis and is inhibitable by the CrmA protein. Other caspase-3 substrates include DNA-PK, actin, GAS2, procaspase-6, etc.
Brand:CaymanSKU:13911- 1 eaAvailable on backorder
Antigen: recombinant full-length human caspase-3 • Host: mouse, clone 31A893 • Cross Reactivity: (+) human caspase-3 • Application(s): WB • Caspase-3 cleaves the death substrate PARP to a specific 85 kDa form observed during apoptosis and is inhibitable by the CrmA protein. Other caspase-3 substrates include DNA-PK, actin, GAS2, procaspase-6, etc.
Brand:CaymanSKU:13911- 1 ea
Antigen: human caspase-8 amino acids PVETDSEEQP • Host: mouse, clone 90A992 • Isotype: IgG1 • Cross Reactivity: (+) human, chimpanzee, and Rhesus monkey caspase-8 • Application(s): FC, IHC (paraffin-embedded tissue), and WB • Caspase-8 forms a direct link between the activation of CD95 and the caspase pathway. Overexpression of caspase-8 induces apoptosis, which can be blocked by inhibitors specific for the ICE family.
Brand:CaymanSKU:13913- 1 eaAvailable on backorder
Antigen: human caspase-8 amino acids PVETDSEEQP • Host: mouse, clone 90A992 • Isotype: IgG1 • Cross Reactivity: (+) human, chimpanzee, and Rhesus monkey caspase-8 • Application(s): FC, IHC (paraffin-embedded tissue), and WB • Caspase-8 forms a direct link between the activation of CD95 and the caspase pathway. Overexpression of caspase-8 induces apoptosis, which can be blocked by inhibitors specific for the ICE family.
Brand:CaymanSKU:13913- 1 ea
Antigen: mixture of synthetic peptides corresponding to rat caspase-9 amino acids 345-359 and 366-383 • Host: rabbit • Cross Reactivity: (+) human, mouse, and rat caspase-9 • Application(s): WB • CTD is a novel isoform of rat caspase-9 in which the C-terminus of full-length caspase-9 is replaced with an alternative peptide sequence. It is found primarily in the cytoplasm and was not detected in the nucleus. CTD proenzyme is not processed in the cells and lacks apoptotic activity. The CTD-transfected cells are resistant to caspase induction by cytochrome c, suggesting the CTD acts as a dominant-negative variant.
Brand:CaymanSKU:13915- 1 eaAvailable on backorder
Antigen: mixture of synthetic peptides corresponding to rat caspase-9 amino acids 345-359 and 366-383 • Host: rabbit • Cross Reactivity: (+) human, mouse, and rat caspase-9 • Application(s): WB • CTD is a novel isoform of rat caspase-9 in which the C-terminus of full-length caspase-9 is replaced with an alternative peptide sequence. It is found primarily in the cytoplasm and was not detected in the nucleus. CTD proenzyme is not processed in the cells and lacks apoptotic activity. The CTD-transfected cells are resistant to caspase induction by cytochrome c, suggesting the CTD acts as a dominant-negative variant.
Brand:CaymanSKU:13915- 1 ea
Antigen: human caspase-9 amino acids 299-318 • Host: rabbit • Application(s): WB • Caspase-9 is activated by granzyme B, CPP32, or by binding Apaf-1. Activated caspase-9 cleaves and activates caspase-3, playing a central role in cell death induced by a wide variety of apoptosis inducers including TNF-α, TRAIL, anti-CD95, FADD, and TRADD.
Brand:CaymanSKU:160790- 1 ea Antigen: human caspase-9 amino acids 299-318 • Host: rabbit • Application(s): WB • Caspase-9 is activated by granzyme B, CPP32, or by binding Apaf-1. Activated caspase-9 cleaves and activates caspase-3, playing a central role in cell death induced by a wide variety of apoptosis inducers including TNF-α, TRAIL, anti-CD95, FADD, and TRADD.
Brand:CaymanSKU:160790- 1 eaAvailable on backorder
Antigen: fusion protein amino acids 1,507-1,733 • Isotype: IgG2b • Host: mouse, clone S57-46 • Cross Reactivity: (+) human, mouse, and rat Cav1.2 • Application(s): ICC, IF, IHC, and WB • Cav1.2 is a cardiac L-type calcium channel important for excitation and contraction of the heart.
Brand:CaymanSKU:13702- 100 µgAvailable on backorder
Antigen: fusion protein amino acids 1,507-1,733 • Isotype: IgG2b • Host: mouse, clone S57-46 • Cross Reactivity: (+) human, mouse, and rat Cav1.2 • Application(s): ICC, IF, IHC, and WB • Cav1.2 is a cardiac L-type calcium channel important for excitation and contraction of the heart.
Brand:CaymanSKU:13702- 100 µg Antigen: fusion protein amino acids 2,025-2,161 (C-terminal) of rat Cav1.3 • Isotype: IgG1 • Host: mouse, clone S38-8 • Cross Reactivity: (+) human, mouse, and rat Cav1.3 • Application(s): ICC, IF, IHC, and WB • Cav1.3 subunits are primarily expressed in neurons and neuroendocrine cells and potentially in heart atria and may figure prominently in atrial arrhythmias. Cav1.3 also carries the primary sensory receptors of the mammalian cochlea and also expressed in the electromotile outer hair cells.
Brand:CaymanSKU:13703- 100 µgAvailable on backorder
Antigen: fusion protein amino acids 2,025-2,161 (C-terminal) of rat Cav1.3 • Isotype: IgG1 • Host: mouse, clone S38-8 • Cross Reactivity: (+) human, mouse, and rat Cav1.3 • Application(s): ICC, IF, IHC, and WB • Cav1.3 subunits are primarily expressed in neurons and neuroendocrine cells and potentially in heart atria and may figure prominently in atrial arrhythmias. Cav1.3 also carries the primary sensory receptors of the mammalian cochlea and also expressed in the electromotile outer hair cells.
Brand:CaymanSKU:13703- 100 µg Antigen: fusion protein amino acids 859-875 (N-terminal) of human Cav1.3 • Isotype: IgG2a • Host: mouse, clone S48A-9 • Cross Reactivity: (+) human, mouse, and rat Cav1.3 • Application(s): ICC, IHC, and WB • Cav1.3 subunits are primarily expressed in neurons and neuroendocrine cells and potentially in heart atria and may figure prominently in atrial arrhythmias. Cav1.3 also carries the primary sensory receptors of the mammalian cochlea and also expressed in the electromotile outer hair cells.
Brand:CaymanSKU:13706- 100 µgAvailable on backorder
Antigen: fusion protein amino acids 859-875 (N-terminal) of human Cav1.3 • Isotype: IgG2a • Host: mouse, clone S48A-9 • Cross Reactivity: (+) human, mouse, and rat Cav1.3 • Application(s): ICC, IHC, and WB • Cav1.3 subunits are primarily expressed in neurons and neuroendocrine cells and potentially in heart atria and may figure prominently in atrial arrhythmias. Cav1.3 also carries the primary sensory receptors of the mammalian cochlea and also expressed in the electromotile outer hair cells.
Brand:CaymanSKU:13706- 100 µg Antigen: fusion protein amino acids 1,019-1,293 (II-III loop) human Cav3.2 • Isotype: IgG1 • Host: mouse, clone S55-10 • Cross Reactivity: (+) human, mouse, and rat Cav3.2 • Application(s): ICC, IHC, and WB • Cav3.2 is a protein encoded by the CACNA1H gene, which is associated with childhood absence epilepsy. Studies suggest that the up-regulations of Cav3.2 may participate in the progession of prostate cancer toward an androgen-independent stage.
Brand:CaymanSKU:13704- 100 µgAvailable on backorder
Antigen: fusion protein amino acids 1,019-1,293 (II-III loop) human Cav3.2 • Isotype: IgG1 • Host: mouse, clone S55-10 • Cross Reactivity: (+) human, mouse, and rat Cav3.2 • Application(s): ICC, IHC, and WB • Cav3.2 is a protein encoded by the CACNA1H gene, which is associated with childhood absence epilepsy. Studies suggest that the up-regulations of Cav3.2 may participate in the progession of prostate cancer toward an androgen-independent stage.
Brand:CaymanSKU:13704- 100 µg Antigen: rat Cavβ1 amino acids 19-34 • Isotype: IgG2a • Host: mouse, clone S7-18 • Cross Reactivity: (+) human, mouse, and rat Cavβ1 • Application(s): ICC, IHC, and WB • Cavβ1 plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the α1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation.
Brand:CaymanSKU:13700- 100 µgAvailable on backorder
Antigen: rat Cavβ1 amino acids 19-34 • Isotype: IgG2a • Host: mouse, clone S7-18 • Cross Reactivity: (+) human, mouse, and rat Cavβ1 • Application(s): ICC, IHC, and WB • Cavβ1 plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the α1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation.
Brand:CaymanSKU:13700- 100 µg Antigen: rat Cavβ4 amino acids 458-474 • Isotype: IgG1 • Host: mouse, clone S10-7 • Cross Reactivity: (+) human, mouse, and rat Cavβ4 • Application(s): ICC, IF, IHC, and WB • Cavβ4 plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the α1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation.
Brand:CaymanSKU:13701- 100 µgAvailable on backorder
Antigen: rat Cavβ4 amino acids 458-474 • Isotype: IgG1 • Host: mouse, clone S10-7 • Cross Reactivity: (+) human, mouse, and rat Cavβ4 • Application(s): ICC, IF, IHC, and WB • Cavβ4 plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the α1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation.
Brand:CaymanSKU:13701- 100 µg
Immunogen: Synthetic peptide from the C-terminal region of human protein CB1 receptor • Host: rabbit • Species Reactivity: (+) human, mouse, and rat CB1 receptor • Application(s): IHC and WB • This antibody has been raised against the C-terminal (amino acids 461-472) intracellular region of the human CB1 receptor, a GPCR that binds the active component of cannabis, D9-tetrahydrocannabinol
Brand:CaymanSKU:10006590- 1 eaAvailable on backorder
Immunogen: Synthetic peptide from the C-terminal region of human protein CB1 receptor • Host: rabbit • Species Reactivity: (+) human, mouse, and rat CB1 receptor • Application(s): IHC and WB • This antibody has been raised against the C-terminal (amino acids 461-472) intracellular region of the human CB1 receptor, a GPCR that binds the active component of cannabis, D9-tetrahydrocannabinol
Brand:CaymanSKU:10006590- 1 ea
Immunogen: Synthetic peptide from the N-terminal extracellular region of human CB1 receptor • Species Reactivity: (+) Human, mouse, and rat • Host: Rabbit • Applications: WB and IHC
Brand:CaymanSKU:101500- 1 ea Immunogen: Synthetic peptide from the N-terminal extracellular region of human CB1 receptor • Species Reactivity: (+) Human, mouse, and rat • Host: Rabbit • Applications: WB and IHC
Brand:CaymanSKU:101500- 1 eaAvailable on backorder
Immunogen: Synthetic peptide from the N-terminal region of human CB2 receptor • Host: Rabbit • Species Reactivity: (+) Human and mouse • Cross Reactivity: (+) CB2 receptor • Applications: IHC and WB
Brand:CaymanSKU:101550- 1 ea