Chemicals
Showing 41101–41137 of 41137 results
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Δ2-trans Eicosenoic acid is an α,β-unsaturated fatty acid that is a bi-product of the synthesis of Δ2-cis eicosenoic acid. Δ2-cis eicosenoic acid and its salts have potential medical use for treating diabetes and improving lipid metabolism. A related compound, 2-octadecenoic acid, has been shown to improve liver function and decrease blood sugar in streptozocin-induced diabetic rats.{13726}
Brand:CaymanSKU:10007622 - 10 mgAvailable on backorder
Δ2-trans Eicosenoic acid is an α,β-unsaturated fatty acid that is a bi-product of the synthesis of Δ2-cis eicosenoic acid. Δ2-cis eicosenoic acid and its salts have potential medical use for treating diabetes and improving lipid metabolism. A related compound, 2-octadecenoic acid, has been shown to improve liver function and decrease blood sugar in streptozocin-induced diabetic rats.{13726}
Brand:CaymanSKU:10007622 - 100 mgAvailable on backorder
Δ2-trans Eicosenoic acid is an α,β-unsaturated fatty acid that is a bi-product of the synthesis of Δ2-cis eicosenoic acid. Δ2-cis eicosenoic acid and its salts have potential medical use for treating diabetes and improving lipid metabolism. A related compound, 2-octadecenoic acid, has been shown to improve liver function and decrease blood sugar in streptozocin-induced diabetic rats.{13726}
Brand:CaymanSKU:10007622 - 5 mgAvailable on backorder
Δ2-trans Eicosenoic acid is an α,β-unsaturated fatty acid that is a bi-product of the synthesis of Δ2-cis eicosenoic acid. Δ2-cis eicosenoic acid and its salts have potential medical use for treating diabetes and improving lipid metabolism. A related compound, 2-octadecenoic acid, has been shown to improve liver function and decrease blood sugar in streptozocin-induced diabetic rats.{13726}
Brand:CaymanSKU:10007622 - 50 mgAvailable on backorder
Formation of cis monoenoic acids from unsaturated fatty acids, such as palmitoleic acid (9-cis-hexadecenoic acid) from palmitic acid occurs readily in animal tissues.{20375} Δ2-trans-Hexadecenoic acid is an intermediate formed in the β-oxidation of palmitic acid.{20376} In a model meant to simulate gastric ulceration, Δ2-trans-hexadecenoic acid at 10 mg/kg significantly inhibits gastric juice secretion in pylorus-ligated rats.{20377}
Brand:CaymanSKU:11132 - 10 mgAvailable on backorder
Formation of cis monoenoic acids from unsaturated fatty acids, such as palmitoleic acid (9-cis-hexadecenoic acid) from palmitic acid occurs readily in animal tissues.{20375} Δ2-trans-Hexadecenoic acid is an intermediate formed in the β-oxidation of palmitic acid.{20376} In a model meant to simulate gastric ulceration, Δ2-trans-hexadecenoic acid at 10 mg/kg significantly inhibits gastric juice secretion in pylorus-ligated rats.{20377}
Brand:CaymanSKU:11132 - 100 mgAvailable on backorder
Formation of cis monoenoic acids from unsaturated fatty acids, such as palmitoleic acid (9-cis-hexadecenoic acid) from palmitic acid occurs readily in animal tissues.{20375} Δ2-trans-Hexadecenoic acid is an intermediate formed in the β-oxidation of palmitic acid.{20376} In a model meant to simulate gastric ulceration, Δ2-trans-hexadecenoic acid at 10 mg/kg significantly inhibits gastric juice secretion in pylorus-ligated rats.{20377}
Brand:CaymanSKU:11132 - 5 mgAvailable on backorder
Formation of cis monoenoic acids from unsaturated fatty acids, such as palmitoleic acid (9-cis-hexadecenoic acid) from palmitic acid occurs readily in animal tissues.{20375} Δ2-trans-Hexadecenoic acid is an intermediate formed in the β-oxidation of palmitic acid.{20376} In a model meant to simulate gastric ulceration, Δ2-trans-hexadecenoic acid at 10 mg/kg significantly inhibits gastric juice secretion in pylorus-ligated rats.{20377}
Brand:CaymanSKU:11132 - 50 mgAvailable on backorder
Δ4-Abiraterone (D4A) is an active metabolite of the CYP17A1 inhibitor abiraterone (Item No. 9002768).{47328} D4A is an androgen receptor antagonist (IC50 = 5.3 nM) that reduces expression of the androgen receptor target genes PSA, TMPRSS2, and FKBP5 in LNCaP, LAPC4, and C4-2 cell lines. It inhibits the cytochrome P450 (CYP) isoform CYP17A1 by 66.5% when used at a concentration of 1 nM. D4A (10 μM) also blocks SRD5A conversion of Δ4-androstenedione to 5α-androstanedione in LAPC4 cells. In vivo, D4A delays tumor progression in a VCaP mouse xenograft model and increases progression-free survival in a C4-2 mouse xenograft model.
Brand:CaymanSKU:27594 - 1 mgAvailable on backorder
Δ4-Abiraterone (D4A) is an active metabolite of the CYP17A1 inhibitor abiraterone (Item No. 9002768).{47328} D4A is an androgen receptor antagonist (IC50 = 5.3 nM) that reduces expression of the androgen receptor target genes PSA, TMPRSS2, and FKBP5 in LNCaP, LAPC4, and C4-2 cell lines. It inhibits the cytochrome P450 (CYP) isoform CYP17A1 by 66.5% when used at a concentration of 1 nM. D4A (10 μM) also blocks SRD5A conversion of Δ4-androstenedione to 5α-androstanedione in LAPC4 cells. In vivo, D4A delays tumor progression in a VCaP mouse xenograft model and increases progression-free survival in a C4-2 mouse xenograft model.
Brand:CaymanSKU:27594 - 10 mgAvailable on backorder
Δ4-Abiraterone (D4A) is an active metabolite of the CYP17A1 inhibitor abiraterone (Item No. 9002768).{47328} D4A is an androgen receptor antagonist (IC50 = 5.3 nM) that reduces expression of the androgen receptor target genes PSA, TMPRSS2, and FKBP5 in LNCaP, LAPC4, and C4-2 cell lines. It inhibits the cytochrome P450 (CYP) isoform CYP17A1 by 66.5% when used at a concentration of 1 nM. D4A (10 μM) also blocks SRD5A conversion of Δ4-androstenedione to 5α-androstanedione in LAPC4 cells. In vivo, D4A delays tumor progression in a VCaP mouse xenograft model and increases progression-free survival in a C4-2 mouse xenograft model.
Brand:CaymanSKU:27594 - 5 mgAvailable on backorder
During unfavorable environmental conditions, C. elegans larvae undergo arrest and form dauer larvae that can attach to other animals as a parasitic strategy for survival.{22033,22027} DAF-12 is an orphan nuclear hormone receptor that regulates dauer larva diapause, reproductive development, fat metabolism, and life cycle/longevity in C. elegans.{22030,22029,22015} DAF-12 is required for entry into dauer when it is not bound to ligand by acting as a transcriptional repressor of target genes that favor reproductive development. Δ4-Dafachronic acid is a racemic version of a sterol-derived hormone that acts as a ligand of DAF-12.{22030,22032,22014,22028} Δ4-Dafachronic acid binds to and transactivates DAF-12, rescuing hormone deficiency in transgenic dauer larvae and promoting reproductive maturation into adults.{22032,22031,22033} The (25S) diastereomer of Δ4-dafachronic acid is significantly more potent than its (25R) counterpart (EC50s = 23 and 66 nM, respectively).{22014}
Brand:CaymanSKU:- During unfavorable environmental conditions, C. elegans larvae undergo arrest and form dauer larvae that can attach to other animals as a parasitic strategy for survival.{22033,22027} DAF-12 is an orphan nuclear hormone receptor that regulates dauer larva diapause, reproductive development, fat metabolism, and life cycle/longevity in C. elegans.{22030,22029,22015} DAF-12 is required for entry into dauer when it is not bound to ligand by acting as a transcriptional repressor of target genes that favor reproductive development. Δ4-Dafachronic acid is a racemic version of a sterol-derived hormone that acts as a ligand of DAF-12.{22030,22032,22014,22028} Δ4-Dafachronic acid binds to and transactivates DAF-12, rescuing hormone deficiency in transgenic dauer larvae and promoting reproductive maturation into adults.{22032,22031,22033} The (25S) diastereomer of Δ4-dafachronic acid is significantly more potent than its (25R) counterpart (EC50s = 23 and 66 nM, respectively).{22014}
Brand:CaymanSKU:- During unfavorable environmental conditions, C. elegans larvae undergo arrest and form dauer larvae that can attach to other animals as a parasitic strategy for survival.{22033,22027} DAF-12 is an orphan nuclear hormone receptor that regulates dauer larva diapause, reproductive development, fat metabolism, and life cycle/longevity in C. elegans.{22030,22029,22015} DAF-12 is required for entry into dauer when it is not bound to ligand by acting as a transcriptional repressor of target genes that favor reproductive development. Δ4-Dafachronic acid is a racemic version of a sterol-derived hormone that acts as a ligand of DAF-12.{22030,22032,22014,22028} Δ4-Dafachronic acid binds to and transactivates DAF-12, rescuing hormone deficiency in transgenic dauer larvae and promoting reproductive maturation into adults.{22032,22031,22033} The (25S) diastereomer of Δ4-dafachronic acid is significantly more potent than its (25R) counterpart (EC50s = 23 and 66 nM, respectively).{22014}
Brand:CaymanSKU:-
Δ5-Avenasterol is a phytosterol that has been found in various plant extracts, including D. metel, D. innoxia, D. stramonium, D. tatula, H. muticus, and H. niger.{48919}
Brand:CaymanSKU:30154 - 1 mgAvailable on backorder
Δ7-Avenasterol is a phytosterol that has been found in a variety of plant oils and grains, including olive and soybean oils and wheat, oats, and rye, and has antioxidant activities.{52392,52393} It reduces temperature-induced oxidation of safflower oil.{52394}
Brand:CaymanSKU:30155 - 500 µgAvailable on backorder
Δ8-Tetrahydrocannabivarin (Item No. 27322) is an analytical reference standard categorized as a cannabinoid.{35714} Δ8-Tetrahydrocannabivarin is regulated as a Schedule I compound in the United States. This product is intended for research and forensic applications. This item has been tested to contain ≤0.3% Δ9-THC on a dry weight basis meeting the 2018 Farm Bill requirements to be a non-controlled substance in the U.S.
Brand:CaymanSKU:27322 - 10 mgAvailable on backorder
Δ8-Tetrahydrocannabivarin (Item No. 27322) is an analytical reference standard categorized as a cannabinoid.{35714} Δ8-Tetrahydrocannabivarin is regulated as a Schedule I compound in the United States. This product is intended for research and forensic applications. This item has been tested to contain ≤0.3% Δ9-THC on a dry weight basis meeting the 2018 Farm Bill requirements to be a non-controlled substance in the U.S.
Brand:CaymanSKU:27322 - 5 mgAvailable on backorder
Δ8-Tetrahydrocannabivarin (Item No. 27322) is an analytical reference standard categorized as a cannabinoid.{35714} Δ8-Tetrahydrocannabivarin is regulated as a Schedule I compound in the United States. This product is intended for research and forensic applications. This item has been tested to contain ≤0.3% Δ9-THC on a dry weight basis meeting the 2018 Farm Bill requirements to be a non-controlled substance in the U.S.
Brand:CaymanSKU:27322 - 50 mgAvailable on backorder
Δ8-THC-d9 (exempt preparation) (Item No. 22873) is intended for use as an internal standard for the quantification of Δ8-THC (Item Nos. 14042 | ISO60158) by GC- or LC-MS. Δ8-THC is categorized as a phytocannabinoid.{19834} Δ8-THC is regulated as a Schedule I compound in the United States. Δ8-THC-d9 (exempt preparation) (Item No. 22873) is provided as a DEA exempt preparation. This product is intended for research and forensic applications.
Brand:CaymanSKU:22873 - 1 mgAvailable on backorder
Δ8-THCA-A (Item No. 25271) is an analytical reference standard that is structurally similar to known phytocannabinoids. Δ8-THCA-A is regulated as a Schedule I compound in the United States. This product is intended for research and forensic applications. This item has been tested to contain ≤0.3% Δ9-THC on a dry weight basis meeting the 2018 Farm Bill requirements to be a non-controlled substance in the U.S.
Brand:CaymanSKU:25271 - 1 mgAvailable on backorder
Δ9-THCB (Item No. 29306) is an analytical reference standard categorized as a phytocannabinoid.{50422,50421,50945} Δ9-THCB has been found in Cannabis samples seized by police. This product is intended for research and forensic applications. This item has been tested to contain ≤0.3% Δ9-THC on a dry weight basis meeting the 2018 Farm Bill requirements to be a non-controlled substance in the U.S.
Brand:CaymanSKU:29306 - 1 mgAvailable on backorder
Δ9-THCB (Item No. 29306) is an analytical reference standard categorized as a phytocannabinoid.{50422,50421,50945} Δ9-THCB has been found in Cannabis samples seized by police. This product is intended for research and forensic applications. This item has been tested to contain ≤0.3% Δ9-THC on a dry weight basis meeting the 2018 Farm Bill requirements to be a non-controlled substance in the U.S.
Brand:CaymanSKU:29306 - 5 mgAvailable on backorder
Δ9-THCP (Item No. 30171) is an analytical reference standard categorized as a phytocannabinoid.{50948} Δ9-THCP has been found in Cannabis. This product is intended for research and forensic applications. This item has been tested to contain ≤0.3% Δ9-THC on a dry weight basis meeting the 2018 Farm Bill requirements to be a non-controlled substance in the U.S.
Brand:CaymanSKU:30171 - 1 mgAvailable on backorder
Δ9-THCP (Item No. 30171) is an analytical reference standard categorized as a phytocannabinoid.{50948} Δ9-THCP has been found in Cannabis. This product is intended for research and forensic applications. This item has been tested to contain ≤0.3% Δ9-THC on a dry weight basis meeting the 2018 Farm Bill requirements to be a non-controlled substance in the U.S.
Brand:CaymanSKU:30171 - 5 mgAvailable on backorder
ω-3 Arachidonic acid is a rare PUFA found in trace amounts in dietary sources. ω-3 Fatty acids are now known to be essential for infant growth and development and protect against heart disease, thrombosis, hypertension, and inflammatory and autoimmune disorders.{5525} In human platelet membranes, ω-3 arachidonic acid inhibits arachidonoyl-CoA synthetase with a Ki of 14 µM. It also inhibits arachidonoyl-CoA synthetase in calf brain extracts with an IC50 value of about 5 µM.{2166}
Brand:CaymanSKU:90011 - 1 mgAvailable on backorder
ω-3 Arachidonic acid is a rare PUFA found in trace amounts in dietary sources. ω-3 Fatty acids are now known to be essential for infant growth and development and protect against heart disease, thrombosis, hypertension, and inflammatory and autoimmune disorders.{5525} In human platelet membranes, ω-3 arachidonic acid inhibits arachidonoyl-CoA synthetase with a Ki of 14 µM. It also inhibits arachidonoyl-CoA synthetase in calf brain extracts with an IC50 value of about 5 µM.{2166}
Brand:CaymanSKU:90011 - 10 mgAvailable on backorder
ω-3 Arachidonic acid is a rare PUFA found in trace amounts in dietary sources. ω-3 Fatty acids are now known to be essential for infant growth and development and protect against heart disease, thrombosis, hypertension, and inflammatory and autoimmune disorders.{5525} In human platelet membranes, ω-3 arachidonic acid inhibits arachidonoyl-CoA synthetase with a Ki of 14 µM. It also inhibits arachidonoyl-CoA synthetase in calf brain extracts with an IC50 value of about 5 µM.{2166}
Brand:CaymanSKU:90011 - 5 mgAvailable on backorder
ω-3 Arachidonic acid is a rare PUFA found in trace amounts in dietary sources. ω-3 Fatty acids are now known to be essential for infant growth and development and protect against heart disease, thrombosis, hypertension, and inflammatory and autoimmune disorders.{5525} In human platelet membranes, ω-3 arachidonic acid inhibits arachidonoyl-CoA synthetase with a Ki of 14 µM. It also inhibits arachidonoyl-CoA synthetase in calf brain extracts with an IC50 value of about 5 µM.{2166}
Brand:CaymanSKU:90011 - 500 µgAvailable on backorder
ω-3 Arachidonic acid is a rare polyunsaturated fatty acid found in trace amounts in dietary sources. ω-3 Fatty acids are known to be essential for infant growth and development and they protect against heart disease, thrombosis, hypertension, as well as inflammatory and autoimmune disorders.{5525} In human platelet membranes, ω-3 arachidonic acid inhibits arachidonoyl-CoA synthetase with a Ki of 14 µM. It also inhibits arachidonoyl-CoA synthetase in calf brain extracts with an IC50 value of about 5 µM.{2166} ω-3 Arachidonic acid ethyl ester is a more lipophilic form of the free acid.
Brand:CaymanSKU:10009348 - 1 mgAvailable on backorder
ω-3 Arachidonic acid is a rare polyunsaturated fatty acid found in trace amounts in dietary sources. ω-3 Fatty acids are known to be essential for infant growth and development and they protect against heart disease, thrombosis, hypertension, as well as inflammatory and autoimmune disorders.{5525} In human platelet membranes, ω-3 arachidonic acid inhibits arachidonoyl-CoA synthetase with a Ki of 14 µM. It also inhibits arachidonoyl-CoA synthetase in calf brain extracts with an IC50 value of about 5 µM.{2166} ω-3 Arachidonic acid ethyl ester is a more lipophilic form of the free acid.
Brand:CaymanSKU:10009348 - 10 mgAvailable on backorder
ω-3 Arachidonic acid is a rare polyunsaturated fatty acid found in trace amounts in dietary sources. ω-3 Fatty acids are known to be essential for infant growth and development and they protect against heart disease, thrombosis, hypertension, as well as inflammatory and autoimmune disorders.{5525} In human platelet membranes, ω-3 arachidonic acid inhibits arachidonoyl-CoA synthetase with a Ki of 14 µM. It also inhibits arachidonoyl-CoA synthetase in calf brain extracts with an IC50 value of about 5 µM.{2166} ω-3 Arachidonic acid ethyl ester is a more lipophilic form of the free acid.
Brand:CaymanSKU:10009348 - 5 mgAvailable on backorder
ω-3 Arachidonic acid is a rare polyunsaturated fatty acid found in trace amounts in dietary sources. ω-3 Fatty acids are known to be essential for infant growth and development and they protect against heart disease, thrombosis, hypertension, as well as inflammatory and autoimmune disorders.{5525} In human platelet membranes, ω-3 arachidonic acid inhibits arachidonoyl-CoA synthetase with a Ki of 14 µM. It also inhibits arachidonoyl-CoA synthetase in calf brain extracts with an IC50 value of about 5 µM.{2166} ω-3 Arachidonic acid ethyl ester is a more lipophilic form of the free acid.
Brand:CaymanSKU:10009348 - 500 µgAvailable on backorder
ω-3 Fatty acids, represented primarily by docosahexaenoic acid, eicosapentaenoic acid, and α-linoleate, are essential dietary nutrients required for normal growth and development. ω-3 Arachidonic acid methyl ester is a neutral, lipid-soluble form of the rare fatty acid ω-3 arachidonic acid. The ω-3 fatty acids, as a group, are associated with decreased inflammatory and autoimmune activity, and a reduction in thrombosis and platelet activation.{5525}
Brand:CaymanSKU:10006454 - 1 mgAvailable on backorder
ω-3 Fatty acids, represented primarily by docosahexaenoic acid, eicosapentaenoic acid, and α-linoleate, are essential dietary nutrients required for normal growth and development. ω-3 Arachidonic acid methyl ester is a neutral, lipid-soluble form of the rare fatty acid ω-3 arachidonic acid. The ω-3 fatty acids, as a group, are associated with decreased inflammatory and autoimmune activity, and a reduction in thrombosis and platelet activation.{5525}
Brand:CaymanSKU:10006454 - 10 mgAvailable on backorder
ω-3 Fatty acids, represented primarily by docosahexaenoic acid, eicosapentaenoic acid, and α-linoleate, are essential dietary nutrients required for normal growth and development. ω-3 Arachidonic acid methyl ester is a neutral, lipid-soluble form of the rare fatty acid ω-3 arachidonic acid. The ω-3 fatty acids, as a group, are associated with decreased inflammatory and autoimmune activity, and a reduction in thrombosis and platelet activation.{5525}
Brand:CaymanSKU:10006454 - 5 mgAvailable on backorder
ω-3 Fatty acids, represented primarily by docosahexaenoic acid, eicosapentaenoic acid, and α-linoleate, are essential dietary nutrients required for normal growth and development. ω-3 Arachidonic acid methyl ester is a neutral, lipid-soluble form of the rare fatty acid ω-3 arachidonic acid. The ω-3 fatty acids, as a group, are associated with decreased inflammatory and autoimmune activity, and a reduction in thrombosis and platelet activation.{5525}
Brand:CaymanSKU:10006454 - 500 µgAvailable on backorder