Thromboxane B2 Express ELISA Kit – Monoclonal – 96 solid wells

Brand:
Cayman
Storage:
-20

Thromboxane A2 (TXA2) is produced from arachidonic acid by many cells and causes irreversible platelet aggregation and contraction of vascular and bronchial smooth muscle.{487,6062,6063} TXA2 is rapidly hydrolyzed non-enzymatically to TXB2, which is then quickly metabolized to urinary metabolites for clearance by the kidneys. Urinary analysis of TXB2 accurately reflects intrarenal TXA2 synthesis,{6304} while measurement of 11-dehydro and 2,3-dinor TX metabolites gives the best estimate of systemic TXA2 secretion.{717,868} Cayman’s TXB2 Express ELISA is a competitive assay that provides accurate measurements of TXB2 from a variety of sample types. As the name implies, this kit was designed for rapid measurements of TXB2.  

 

Available on backorder

SKU: 10004023 - 96 solid wells Category:

Description

Thromboxane A2 (TXA2), produced from arachidonic acid, causes irreversible platelet aggregation and contraction of vascular and bronchial smooth muscle. TXA2 is rapidly hydrolyzed non-enzymatically to TXB2, which is then quickly metabolized to urinary metabolites for clearance by the kidneys. Urinary analysis of TXB2 accurately reflects intrarenal TXA2 synthesis, while measurement of 11-dehydro and 2,3-dinor TX metabolites gives the best estimate of systemic TXA2 secretion. Cayman’s TXB2 Express ELISA is a competitive assay that provides a rapid, accurate measurement of TXB2 from plasma, urine, and cell culture supernatants. The assay has a range from 15.6-2,000 pg/ml and a sensitivity (80% B/B0) of approximately 45 pg/ml.


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Synonyms:  TXB2 Express EIA

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Origin: Animal/Eel|Animal/Mouse|Animal/Goat|Animal/Bovine


Application|ELISA||Product Type|Assay Kits|ELISA||Research Area|Cardiovascular System|Blood|Coagulation & Hemostasis||Research Area|Immunology & Inflammation||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway