PEPCK Polyclonal Antibody – 1 ea

Brand:
Cayman
Storage:

Phosphoenolpyruvate carboxykinase (PEPCK) is a hormonally regulated enzyme responsible for the first committed step in gluconeogenesis, catalyzing the conversion of oxaloacetate to phosphoenolpyruvate.{13231,13234} PEPCK mRNA is most abundant in the liver, kidney cortex, and white adipose tissue but is also found in brown fat, the mammary gland during lactation, and the small intestine.{13234} Both non-insulin-dependent diabetes mellitus and streptozotocin-induced diabetes result in elevated PEPCK activity, protein, and mRNA.{13231,13237} Two isozymes of PEPCK have been identified, cytosolic and mitochondrial.{13240} Cayman’s PEPCK polyclonal antibody was generated against murine cytosolic PEPCK and detects the protein at 63 kDa by western blotting in rat and murine samples.  

 

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SKU: 10004943 - 1 ea Category:

Description

Immunoge: Peptide from the N-terminal region of mouse PEPCK · Host: Rabbit · Species Reactivity: (+) mouse and rat PEPCK protein · Application(s): WB • PEPCK catalyzes the conversion of oxaloacetate to phosphoenolpyruvate, the first committed step in gluconeogenesis. Both non-insulin-dependent diabetes mellitus and streptozotocin-induced diabetes result in elevated PEPCK activity, protein, and mRNA. This antibody was generated against mouse cytosolic PEPCK.


Synonyms: Pck1|PEPCK-c|Phosphoenolpyruvate carboxykinase

Immunogen: Peptide from the N-terminal region of mouse PEPCK

Formulation: 500 µl of peptide affinity-purified antibody

Isotype:

Applications: WB

Origin: Animal/Rabbit

Stability: 365 days


Application|Western Blot||Product Type|Antibodies|Blocking Peptides||Product Type|Antibodies|Monoclonal Antibodies||Research Area|Endocrinology & Metabolism|Carbohydrate Metabolism||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Diabetes