MCAD Polyclonal Antibody – 500 µl

Brand:
Cayman
Storage:

Medium-chain fatty acyl-CoA dehydrogenase (MCAD) is a mitochondrial enzyme that catalyzes the first step in the βoxidation of fatty acids. MCAD expression is induced during periods of fasting, when reliance on fatty acids for energy is increased.{7572,7416} The promoter for MCAD contains a peroxisome proliferator response element (PPRE) and is regulated transcriptionally by peroxisome proliferator-activated receptor alpha (PPARα), a ligand-activated transcription factor involved in the regulation of lipid homeostasis.{7572,7571,4136} Because of this, MCAD expression can be used as a marker to evaluate the in vivo activity of PPARα.{7572,7416} Human MCAD is approximately 87% homologous to porcine and rat MCAD, respectively.{7568,7570} MCAD is expressed in liver, heart, kidney, and skeletal muscle.  

 

Available on backorder

SKU: 101730 - 500 µl Category:

Description

Immunogen: Full length human recombinant MCAD • Host: Rabbit • Species Reactivity: (+) Human, mouse, ovine, porcine MCAD; other species not tested • Application(s): WB; other applications not tested • MCAD is a mitochondrial enzyme that catalyzes the first step in the β-oxidation of fatty acids. Its expression is induced during periods of fasting and is regulated by PPARα, a ligand-activated transcription factor involved in the regulation of lipid homeostasis. MCAD expression can be used as a marker to evaluate the in vivo activity of PPARα.


Synonyms: ACADM|Medium-chain Fatty Acyl-CoA Dehydrogenase|Medium-chain Specific Acyl-CoA Dehydrogenase mitochondrial

Immunogen: Full length human recombinant MCAD

Formulation: Protein A-purified polyclonal antibody

Isotype:

Applications: WB; other applications not tested

Origin: Animal/Rabbit

Stability: 365 days


Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Cell Biology|Mitochondrial Biology||Research Area|Endocrinology & Metabolism|Hormones & Receptors|PPARs