Immunogen: Peptide from the C-terminal region of rat lysoPLD • Host: Rabbit • Species Reactivity: (+) Human

Lysophospholipase D Polyclonal Antibody – 1 ea

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Cayman
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Lysophosphatidic acid (LPA) is an extracellular signaling lipid that evokes multiple biological functions including induction of platelet aggregation, smooth muscle contraction, and stimulation of cell proliferation and chemotaxis.{12477} Lysophospholipase D (lysoPLD) was first discovered in 1999 as the enzyme responsible for generating LPA from lysophosphatidylcholine (LPC).{13068} It was later revealed to be identical to an autocrine motility factor, autotaxin (ATX), which plays a role in tumor progression and metastasis.{13069,13071} LysoPLD/ATX mRNA is widely expressed with highest levels found in brain, ovary, lung, intestine, and testis.{13067,13070} Rat lysoPLD is composed of 885 amino acids with an estimated molecular weight of 101 kDa. The protein is reported to be heavily glycosylated and thus its apparent size on SDS-PAGE may be run as high as 125 kDa. Useful positive controls include cerebrospinal fluid, mouse ascites or seminal plasma.  

 

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SKU: 10005375 - 1 ea Category:

Description

Immunogen: Peptide from the C-terminal region of rat lysoPLD • Host: Rabbit • Species Reactivity: (+) Human, mouse, and rat • Applications: ICC, IHC and WB

Synonyms: Autotaxin|ENPP2|LysoPLD

Immunogen: Peptide from the C-terminal region of rat lysoPLD

Formulation: 500 µl of Peptide affinity-purified antibody

Isotype:

Applications: ICC, IHC, and WB

Origin: Animal/Rabbit

Stability: 365 days

Application|Immunocytochemistry||Application|Immunohistochemistry||Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Lipid Biochemistry|Glycerophospholipids|Phospholipases

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