Immunogen: Peptide from the C-terminal region of human GRP17 • Host: Rabbit • Cross Reactivity: (+) human; other sepcies not tested • Application(s): IF

GPR17 (C-Term) Polyclonal Antibody (Immunofluorescence) – 1 ea

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Cayman
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GPR17 is a G protein-coupled receptor that has been identified as a dualistic receptor recognizing signals from two unrelated chemical families: nucleotides and cysteinyl leukotrienes (CysLTs).{16467} The deorphanization of GPR17 supports the suggested crosstalk between nucleotides and CysLTs during inflammation and injury. mRNA transcripts encoding this transmembrane receptor are most strongly expressed in the brain, kidney, and heart. Upon ischemic injury, GPR17 is upregulated in these tissues and its inhibition has been shown to decrease ischemic damage. This finding suggests GPR17 as a pharmacological target of ischemic injury.{16467} Cayman’s GPR17 (C-Term) Polyclonal Antibody (Immunofluorescence) is a peptide affinity-purified polyclonal antibody that recognizes the C-terminal region of human GPR17. This protein exists in two isoforms, differing by 28 amino acids at the receptor N-terminus. The longer form of the protein consists of 367 amino acids with a calculated molecular weight of 41 kDa. The human and rat proteins share 89% amino acid identity.{16467}  

 

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SKU: 17087 - 1 ea Category:

Description

Immunogen: Peptide from the C-terminal region of human GRP17 • Host: Rabbit • Cross Reactivity: (+) human; other sepcies not tested • Application(s): IF

Synonyms: G Protein-Coupled Receptor 17|P2Y-Like Receptor|Uracil Nucleotide/Cysteinyl Leukotriene Receptor

Immunogen: Peptide from the C-terminal region of human GRP17

Formulation: 500 µl of Peptide affinity-purified polyclonal antibody

Isotype:

Applications: IF

Origin:

Stability: 365 days

Application|Immunofluorescence||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Cardiovascular System|Cardiovascular Diseases|Myocardial Infarction||Research Area|Immunology & Inflammation||Research Area|Lipid Biochemistry|Lipoxygenase Pathways

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