Immunogen: Synthetic peptide from the C-terminal region of human COX-2 • Host: Goat • Cross Reactivity: (−) COX-1 from all species • Species Reactivity: (+) Human

Goat Anti-COX-2 (human) Affinity-Purified Polyclonal Antibody – 1 ea

Brand:
Cayman
Storage:

Cyclooxygenase (COX) catalyzes the first step in the biosynthesis of prostaglandins (PGs), thromboxanes, and prostacyclins: the conversion of arachidonic acid to PGH2. Discoveries of the induction of COX by a variety of stimuli such as phorbol esters, lipopolysaccharides, and cytokines led to the hypothesis that the inducible form of COX, COX-2, is responsible for the biosynthesis of PGs under acute inflammatory conditions.{4,3463} COX-2 is a 72 kDa protein which has been cloned from a variety of species including human, mouse, rat, and ovine.{2,7,2884,4051}  

 

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SKU: 100034 - 1 ea Category:

Description

Immunogen: Synthetic peptide from the C-terminal region of human COX-2 • Host: Goat • Cross Reactivity: (−) COX-1 from all species • Species Reactivity: (+) Human, mouse, ovine, and rat COX-2 • Application(s): IF, IHC, and WB • Expression of COX-2, the inducible form of COX, is regulated by growth factor tumors, tumor promoters, bacterial endotoxin, and cytokines

Synonyms: Cyclooxygenase-2|PGHS-2|Prostaglandin H Synthase-2

Immunogen: Synthetic peptide from the C-terminal region of human COX-2

Formulation: 500 µl of peptide affinity-purified IgG

Isotype:

Applications: IF, IHC, and WB

Origin: Animal/Goat

Stability: 365 days

Application|Immunocytochemistry||Application|Immunohistochemistry||Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway

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