Immunogen: human GPR40 • Host: rabbit • Species Reactivity: (+) human

FFAR1 (GPR40) Polyclonal Antibody – 1 ea

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Cayman
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GPR40 is a seven transmembrane G Protein-coupled receptor with signalling mediated by medium- and long-chain fatty acids.{13140,13139} Found predominantly in the β-cells of pancreatic islets, it has been implicated in the regulation of insulin secretion.{14194,14741} Overexpression of GPR40 in mouse β cells leads to glucose intolerance suggesting a link between GPR40 expression and diabetes.{14194,14741} The receptor has also been identified as a possible mediator of oleate- and linoleate- stimulated proliferation of the human breast cancer cell line, MCF-7.{14742,13137} GPR40 has a calculated mass of 31.4 kDa bases on its amino acid sequence.  

 

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SKU: 10007205 - 1 ea Category:

Description

Immunogen: human GPR40 • Host: rabbit • Species Reactivity: (+) human, rat, mouse, porcine • Applications: IHC and WB

Synonyms: Free Fatty Acid Receptor 1|G Protein-Coupled Receptor 40

Immunogen: human GPR40

Formulation: 500 ul of peptide affinity-purified antibody

Isotype:

Applications: IHC and WB

Origin: Animal/Rabbit

Stability: 365 days

Application|Immunohistochemistry||Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Cancer||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Diabetes||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Obesity

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