Immunogen: HeLa cells transfected with human BLT1 • Clone designation: 7B1 • Host: Mouse • Cross-Reactivity: (+) BLT1; (−) BLT2

BLT1 Receptor Monoclonal Antibody (Clone 7B1) – 1 ea

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Cayman
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The human BLT1 receptor is a G protein-coupled receptor that mediates the proinflammatory effects of leukotriene B4 (LTB4).{4425} Northern blotting reveals that the BLT1 receptor is highly expressed in leukocytes, U937 cells, and to a much lower extent in spleen and thymus.{4425} Sheep lung membranes have also been identified as a rich source for receptor isolation and purification.{4640} A second, low-affinity LTB4 receptor, BLT2, has also been cloned and characterized.{8280,8525,8743} Cayman Chemical’s BLT1 Receptor Monoclonal Antibody is a useful tool for the detection of human BLT1 by flow cytometry, immunofluorescence, and immunohistochemistry. The antibody does not cross react with the other leukotriene receptors (BLT2, CysLT1, or CysLT2) and does not work for Western blot analysis of BLT1.  

 

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SKU: 120111 - 1 ea Category:

Description

Immunogen: HeLa cells transfected with human BLT1 • Clone designation: 7B1 • Host: Mouse • Cross-Reactivity: (+) BLT1; (−) BLT2, CysLT1, and CysLT2 receptors • Species Reactivity: (+) Human • Isotype: IgG2a • Application(s): FC, IF, and IHC of frozen sections • The human BLT1 receptor is a GPCR that mediates the proinflammatory effects of leukotriene B4 (LTB4). Northern blotting reveals that the BLT1 receptor is highly expressed in leukocytes, U937 cells, and to a much lower extent in spleen and thymus.

Synonyms: BLTR1|Leukotriene B4 Receptor 1|LTB4 Receptor 1

Immunogen: HeLa cells transfected with human BLT1

Formulation: 200 µg of Protein-G purified IgG

Isotype: IgG2a

Applications: FC, IF, and IHC of frozen sections

Origin: Animal/Mouse

Stability: 365 days

Application|Flow Cytometry||Application|Immunofluorescence||Application|Immunohistochemistry||Product Type|Antibodies|Monoclonal Antibodies||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Leukotrienes||Research Area|Immunology & Inflammation|Innate Immunity||Research Area|Lipid Biochemistry|Lipoxygenase Pathways

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