Chemicals
Showing 13951–14100 of 41137 results
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Cyclin-dependent kinase 5 (Cdk5) is a serine/threonine kinase that is predominantly active in neuronal tissues. With p25 or p35, Cdk5 phosphorylates a range of proteins, including histone H1 and tau.{28590} Cdk5 substrate is a synthetic peptide (PKTPKKAKKL) corresponding to a sequence of histone H1. It is phosphorylated by Cdk5 with a Km value of 5 µM.{28589,28591}
Brand:CaymanSKU:-Available on backorder
Cyclin-dependent kinase 5 (Cdk5) is a serine/threonine kinase that is predominantly active in neuronal tissues. With p25 or p35, Cdk5 phosphorylates a range of proteins, including histone H1 and tau.{28590} Cdk5 substrate is a synthetic peptide (PKTPKKAKKL) corresponding to a sequence of histone H1. It is phosphorylated by Cdk5 with a Km value of 5 µM.{28589,28591}
Brand:CaymanSKU:-Available on backorder
Cyclin-dependent kinase 5 (Cdk5) is a serine/threonine kinase that is predominantly active in neuronal tissues. With p25 or p35, Cdk5 phosphorylates a range of proteins, including histone H1 and tau.{28590} Cdk5 substrate is a synthetic peptide (PKTPKKAKKL) corresponding to a sequence of histone H1. It is phosphorylated by Cdk5 with a Km value of 5 µM.{28589,28591}
Brand:CaymanSKU:-Available on backorder
Cyclin-dependent kinase 5 (Cdk5) is a serine/threonine kinase that is predominantly active in neuronal tissues. With p25 or p35, Cdk5 phosphorylates a range of proteins, including histone H1 and tau.{28590} Cdk5 substrate is a synthetic peptide (PKTPKKAKKL) corresponding to a sequence of histone H1. It is phosphorylated by Cdk5 with a Km value of 5 µM.{28589,28591}
Brand:CaymanSKU:-Available on backorder
CDN1163 is an allosteric activator of sarcoplasmic/endoplasmic reticulum Ca2+-ATPase 2 (SERCA2) that enhances calcium uptake in endoplasmic reticulum (ER) vesicles when used at concentrations ranging from 1 to 10 µM.{57074} It decreases peroxide-induced cell death in HEK293 cells. CDN1163 (50 mg/kg) increases calcium uptake in ER microsomes isolated from obese mouse liver. It decreases blood glucose levels, plasma and hepatic triglyceride levels, and plasma cholesterol and malondialdehyde (MDA) levels in obese mice. CDN1163 (50 mg/kg) restores SERCA activity, prevents gastrocnemius muscle loss and contractile dysfunction, and reduces mitochondrial production of reactive oxygen species (ROS) in the CuZnSOD-deficient (Sod-/-) mouse model of oxidative stress-related muscle atrophy and weakness.{57075} It also improves motor deficits in the initiation time (IT), stepping, and cylinder tests for akinesia in a rat model of Parkinson’s disease induced by 6-OHDA (Item No. 25330).{57076}
Brand:CaymanSKU:31123 - 1 mgAvailable on backorder
CDN1163 is an allosteric activator of sarcoplasmic/endoplasmic reticulum Ca2+-ATPase 2 (SERCA2) that enhances calcium uptake in endoplasmic reticulum (ER) vesicles when used at concentrations ranging from 1 to 10 µM.{57074} It decreases peroxide-induced cell death in HEK293 cells. CDN1163 (50 mg/kg) increases calcium uptake in ER microsomes isolated from obese mouse liver. It decreases blood glucose levels, plasma and hepatic triglyceride levels, and plasma cholesterol and malondialdehyde (MDA) levels in obese mice. CDN1163 (50 mg/kg) restores SERCA activity, prevents gastrocnemius muscle loss and contractile dysfunction, and reduces mitochondrial production of reactive oxygen species (ROS) in the CuZnSOD-deficient (Sod-/-) mouse model of oxidative stress-related muscle atrophy and weakness.{57075} It also improves motor deficits in the initiation time (IT), stepping, and cylinder tests for akinesia in a rat model of Parkinson’s disease induced by 6-OHDA (Item No. 25330).{57076}
Brand:CaymanSKU:31123 - 10 mgAvailable on backorder
CDN1163 is an allosteric activator of sarcoplasmic/endoplasmic reticulum Ca2+-ATPase 2 (SERCA2) that enhances calcium uptake in endoplasmic reticulum (ER) vesicles when used at concentrations ranging from 1 to 10 µM.{57074} It decreases peroxide-induced cell death in HEK293 cells. CDN1163 (50 mg/kg) increases calcium uptake in ER microsomes isolated from obese mouse liver. It decreases blood glucose levels, plasma and hepatic triglyceride levels, and plasma cholesterol and malondialdehyde (MDA) levels in obese mice. CDN1163 (50 mg/kg) restores SERCA activity, prevents gastrocnemius muscle loss and contractile dysfunction, and reduces mitochondrial production of reactive oxygen species (ROS) in the CuZnSOD-deficient (Sod-/-) mouse model of oxidative stress-related muscle atrophy and weakness.{57075} It also improves motor deficits in the initiation time (IT), stepping, and cylinder tests for akinesia in a rat model of Parkinson’s disease induced by 6-OHDA (Item No. 25330).{57076}
Brand:CaymanSKU:31123 - 25 mgAvailable on backorder
CDN1163 is an allosteric activator of sarcoplasmic/endoplasmic reticulum Ca2+-ATPase 2 (SERCA2) that enhances calcium uptake in endoplasmic reticulum (ER) vesicles when used at concentrations ranging from 1 to 10 µM.{57074} It decreases peroxide-induced cell death in HEK293 cells. CDN1163 (50 mg/kg) increases calcium uptake in ER microsomes isolated from obese mouse liver. It decreases blood glucose levels, plasma and hepatic triglyceride levels, and plasma cholesterol and malondialdehyde (MDA) levels in obese mice. CDN1163 (50 mg/kg) restores SERCA activity, prevents gastrocnemius muscle loss and contractile dysfunction, and reduces mitochondrial production of reactive oxygen species (ROS) in the CuZnSOD-deficient (Sod-/-) mouse model of oxidative stress-related muscle atrophy and weakness.{57075} It also improves motor deficits in the initiation time (IT), stepping, and cylinder tests for akinesia in a rat model of Parkinson’s disease induced by 6-OHDA (Item No. 25330).{57076}
Brand:CaymanSKU:31123 - 5 mgAvailable on backorder
Exchange protein activated by cAMP (Epac) proteins mediate cAMP signaling independent of protein kinase A (PKA). CE3F4 is an uncompetitive inhibitor of Epac1 activity toward its effector Rap1 in vitro (IC50 = 23 µM) and in cells.{29533,29532}. It has no effect on PKA activity. CE3F4 blocks Epac1-induced autophagy in cardiomyocytes stimulated with isoprenaline and blocks the activation of transient receptor potential canonical (TRPC) channels by the Epac activator 8-pCPT.{29535,29534}
Brand:CaymanSKU:-Available on backorder
Exchange protein activated by cAMP (Epac) proteins mediate cAMP signaling independent of protein kinase A (PKA). CE3F4 is an uncompetitive inhibitor of Epac1 activity toward its effector Rap1 in vitro (IC50 = 23 µM) and in cells.{29533,29532}. It has no effect on PKA activity. CE3F4 blocks Epac1-induced autophagy in cardiomyocytes stimulated with isoprenaline and blocks the activation of transient receptor potential canonical (TRPC) channels by the Epac activator 8-pCPT.{29535,29534}
Brand:CaymanSKU:-Available on backorder
Exchange protein activated by cAMP (Epac) proteins mediate cAMP signaling independent of protein kinase A (PKA). CE3F4 is an uncompetitive inhibitor of Epac1 activity toward its effector Rap1 in vitro (IC50 = 23 µM) and in cells.{29533,29532}. It has no effect on PKA activity. CE3F4 blocks Epac1-induced autophagy in cardiomyocytes stimulated with isoprenaline and blocks the activation of transient receptor potential canonical (TRPC) channels by the Epac activator 8-pCPT.{29535,29534}
Brand:CaymanSKU:-Available on backorder
Cebranopadol is an agonist of nociceptin-, µ-, ĸ-, and δ-opioid receptors (Kis = 0.9, 0.7, 2.6, and 18 nM, respectively).{52240} It is greater than 100-fold selective for these receptors over a panel of more than 100 ion channels, neurotransmitter transporters, receptors, and enzymes, but does bind to the serotonin (5-HT) receptor subtype 5-HT5A with a Ki value of 8.7 nM. Cebranopadol inhibits nociceptin-, DAMGO-, and SNC 80-induced GTPɣS binding in CHO cells expressing nociceptin-, µ-, and δ-opioid receptors, respectively (EC50s = 13, 1.2, and 110 nM, respectively), as well as U69,593-induced GTPɣS binding in HEK293 cells expressing the ĸ-opioid receptor (EC50 = 17 nM). It increases the paw withdrawal threshold in rat models of bone cancer pain and streptozotocin-induced diabetic neuropathy (ED50s = 3.6 and 0.5 µg/kg, respectively, i.v.). Cebranopadol also increases paw weight bearing on the ipsilateral side in a rat model of arthritis induced by complete Freund’s adjuvant (CFA) and M. tuberculosis (ED50 = 5.5 µg/kg, i.v.).
Brand:CaymanSKU:29500 - 10 mgAvailable on backorder
Cebranopadol is an agonist of nociceptin-, µ-, ĸ-, and δ-opioid receptors (Kis = 0.9, 0.7, 2.6, and 18 nM, respectively).{52240} It is greater than 100-fold selective for these receptors over a panel of more than 100 ion channels, neurotransmitter transporters, receptors, and enzymes, but does bind to the serotonin (5-HT) receptor subtype 5-HT5A with a Ki value of 8.7 nM. Cebranopadol inhibits nociceptin-, DAMGO-, and SNC 80-induced GTPɣS binding in CHO cells expressing nociceptin-, µ-, and δ-opioid receptors, respectively (EC50s = 13, 1.2, and 110 nM, respectively), as well as U69,593-induced GTPɣS binding in HEK293 cells expressing the ĸ-opioid receptor (EC50 = 17 nM). It increases the paw withdrawal threshold in rat models of bone cancer pain and streptozotocin-induced diabetic neuropathy (ED50s = 3.6 and 0.5 µg/kg, respectively, i.v.). Cebranopadol also increases paw weight bearing on the ipsilateral side in a rat model of arthritis induced by complete Freund’s adjuvant (CFA) and M. tuberculosis (ED50 = 5.5 µg/kg, i.v.).
Brand:CaymanSKU:29500 - 25 mgAvailable on backorder
Cebranopadol is an agonist of nociceptin-, µ-, ĸ-, and δ-opioid receptors (Kis = 0.9, 0.7, 2.6, and 18 nM, respectively).{52240} It is greater than 100-fold selective for these receptors over a panel of more than 100 ion channels, neurotransmitter transporters, receptors, and enzymes, but does bind to the serotonin (5-HT) receptor subtype 5-HT5A with a Ki value of 8.7 nM. Cebranopadol inhibits nociceptin-, DAMGO-, and SNC 80-induced GTPɣS binding in CHO cells expressing nociceptin-, µ-, and δ-opioid receptors, respectively (EC50s = 13, 1.2, and 110 nM, respectively), as well as U69,593-induced GTPɣS binding in HEK293 cells expressing the ĸ-opioid receptor (EC50 = 17 nM). It increases the paw withdrawal threshold in rat models of bone cancer pain and streptozotocin-induced diabetic neuropathy (ED50s = 3.6 and 0.5 µg/kg, respectively, i.v.). Cebranopadol also increases paw weight bearing on the ipsilateral side in a rat model of arthritis induced by complete Freund’s adjuvant (CFA) and M. tuberculosis (ED50 = 5.5 µg/kg, i.v.).
Brand:CaymanSKU:29500 - 5 mgAvailable on backorder
Receptors for VEGF have central roles in vasculogenesis and angiogenesis and thus serve as targets for cancer therapy.{18368,20203} Cediranib is a potent inhibitor of VEGF receptor tyrosine kinases, including VEGFR1, 2, and 3 (IC50s = 5, 1, and 3 nM, respectively).{24157} It also potently inhibits a variety of other receptor and non-receptor tyrosine kinases, including several in the platelet-derived growth factor, fibroblast growth factor, and endothelial growth factor receptor families.{24157,24156} Cediranib blocks tubule formation by human umbilical vein endothelial cells in vitro and prevents angiogenesis as well as xenograft tumor growth in vivo.{24157} Because of these effects, cediranib has potential use in a range of cancers.{19939,24159,24155}
Brand:CaymanSKU:11495 - 10 mgAvailable on backorder
Receptors for VEGF have central roles in vasculogenesis and angiogenesis and thus serve as targets for cancer therapy.{18368,20203} Cediranib is a potent inhibitor of VEGF receptor tyrosine kinases, including VEGFR1, 2, and 3 (IC50s = 5, 1, and 3 nM, respectively).{24157} It also potently inhibits a variety of other receptor and non-receptor tyrosine kinases, including several in the platelet-derived growth factor, fibroblast growth factor, and endothelial growth factor receptor families.{24157,24156} Cediranib blocks tubule formation by human umbilical vein endothelial cells in vitro and prevents angiogenesis as well as xenograft tumor growth in vivo.{24157} Because of these effects, cediranib has potential use in a range of cancers.{19939,24159,24155}
Brand:CaymanSKU:11495 - 25 mgAvailable on backorder
Receptors for VEGF have central roles in vasculogenesis and angiogenesis and thus serve as targets for cancer therapy.{18368,20203} Cediranib is a potent inhibitor of VEGF receptor tyrosine kinases, including VEGFR1, 2, and 3 (IC50s = 5, 1, and 3 nM, respectively).{24157} It also potently inhibits a variety of other receptor and non-receptor tyrosine kinases, including several in the platelet-derived growth factor, fibroblast growth factor, and endothelial growth factor receptor families.{24157,24156} Cediranib blocks tubule formation by human umbilical vein endothelial cells in vitro and prevents angiogenesis as well as xenograft tumor growth in vivo.{24157} Because of these effects, cediranib has potential use in a range of cancers.{19939,24159,24155}
Brand:CaymanSKU:11495 - 5 mgAvailable on backorder
Cefaclor is a cephalosporin antibiotic that is active against S. pyogenes, S. pneumoniae, S. aureus, P. mirabilis, S. typhi, E. coli, and H. influenzae (MICs = 0.25, 0.25-2, 1-2, 1, 0.5, 1, and 2-4 μg/ml, respectively).{48414} It is protective against S. pyogenes, S. pneumoniae, S. aureus, P. mirabilis, S. typhi, E. coli, and H. influenzae infections in mice (ED50s = 0.08-30.2 mg/kg). Formulations containing cefaclor have been used in the treatment of various bacterial infections.
Brand:CaymanSKU:23626 - 100 mgAvailable on backorder
Cefaclor is a cephalosporin antibiotic that is active against S. pyogenes, S. pneumoniae, S. aureus, P. mirabilis, S. typhi, E. coli, and H. influenzae (MICs = 0.25, 0.25-2, 1-2, 1, 0.5, 1, and 2-4 μg/ml, respectively).{48414} It is protective against S. pyogenes, S. pneumoniae, S. aureus, P. mirabilis, S. typhi, E. coli, and H. influenzae infections in mice (ED50s = 0.08-30.2 mg/kg). Formulations containing cefaclor have been used in the treatment of various bacterial infections.
Brand:CaymanSKU:23626 - 250 mgAvailable on backorder
Cefadroxil is a semisynthetic cephalosporin antibiotic.{42841} It is active against the bacteria B. anthracis, V. cholerae, and P. multocida (MICs = 1, 2, and 4 µg/ml, respectively) among others. Cefadroxil is protective against systemic infections by S. pyogenes, S. pneumoniae, and S. aureus strains in mice with 50% protective dose values (PC50s) of 0.6-2.4, 18-24, and 0.3-29 mg/kg, respectively. Formulations containing cefadroxil have been used in the treatment of a variety of bacterial infections.
Brand:CaymanSKU:20365 -Available on backorder
Cefadroxil is a semisynthetic cephalosporin antibiotic.{42841} It is active against the bacteria B. anthracis, V. cholerae, and P. multocida (MICs = 1, 2, and 4 µg/ml, respectively) among others. Cefadroxil is protective against systemic infections by S. pyogenes, S. pneumoniae, and S. aureus strains in mice with 50% protective dose values (PC50s) of 0.6-2.4, 18-24, and 0.3-29 mg/kg, respectively. Formulations containing cefadroxil have been used in the treatment of a variety of bacterial infections.
Brand:CaymanSKU:20365 -Available on backorder
Cefadroxil is a semisynthetic cephalosporin antibiotic.{42841} It is active against the bacteria B. anthracis, V. cholerae, and P. multocida (MICs = 1, 2, and 4 µg/ml, respectively) among others. Cefadroxil is protective against systemic infections by S. pyogenes, S. pneumoniae, and S. aureus strains in mice with 50% protective dose values (PC50s) of 0.6-2.4, 18-24, and 0.3-29 mg/kg, respectively. Formulations containing cefadroxil have been used in the treatment of a variety of bacterial infections.
Brand:CaymanSKU:20365 -Available on backorder
Cefadroxil is a semisynthetic cephalosporin antibiotic.{42841} It is active against the bacteria B. anthracis, V. cholerae, and P. multocida (MICs = 1, 2, and 4 µg/ml, respectively) among others. Cefadroxil is protective against systemic infections by S. pyogenes, S. pneumoniae, and S. aureus strains in mice with 50% protective dose values (PC50s) of 0.6-2.4, 18-24, and 0.3-29 mg/kg, respectively. Formulations containing cefadroxil have been used in the treatment of a variety of bacterial infections.
Brand:CaymanSKU:20365 -Available on backorder
Cefalothin is a β-lactam cephalosporin antibiotic.{48055,48056} It inhibits the growth of various Gram-positive and Gram-negative bacteria, including several strains of S. pyogenes, S. aureus, C. tetani, N. gonorrhoeae, Salmonella, and Shigella (MICs = 0.1-0.2, 0.312-0.625, 0.078, 1.25, 1.56-6.25, and 3.12-12.5 μg/ml, respectively).{48055} Cefalothin binds to E. coli penicillin-binding proteins (PBPs; IC50s = S. pyogenes, D. pneumoniae, and S. aureus.{48055} Formulations containing cefalothin were previously used in the prophylaxis and treatment of bacterial infections.
Brand:CaymanSKU:26063 - 1 gAvailable on backorder
Cefalothin is a β-lactam cephalosporin antibiotic.{48055,48056} It inhibits the growth of various Gram-positive and Gram-negative bacteria, including several strains of S. pyogenes, S. aureus, C. tetani, N. gonorrhoeae, Salmonella, and Shigella (MICs = 0.1-0.2, 0.312-0.625, 0.078, 1.25, 1.56-6.25, and 3.12-12.5 μg/ml, respectively).{48055} Cefalothin binds to E. coli penicillin-binding proteins (PBPs; IC50s = S. pyogenes, D. pneumoniae, and S. aureus.{48055} Formulations containing cefalothin were previously used in the prophylaxis and treatment of bacterial infections.
Brand:CaymanSKU:26063 - 250 mgAvailable on backorder
Cefalothin is a β-lactam cephalosporin antibiotic.{48055,48056} It inhibits the growth of various Gram-positive and Gram-negative bacteria, including several strains of S. pyogenes, S. aureus, C. tetani, N. gonorrhoeae, Salmonella, and Shigella (MICs = 0.1-0.2, 0.312-0.625, 0.078, 1.25, 1.56-6.25, and 3.12-12.5 μg/ml, respectively).{48055} Cefalothin binds to E. coli penicillin-binding proteins (PBPs; IC50s = S. pyogenes, D. pneumoniae, and S. aureus.{48055} Formulations containing cefalothin were previously used in the prophylaxis and treatment of bacterial infections.
Brand:CaymanSKU:26063 - 5 gAvailable on backorder
Cefalothin is a β-lactam cephalosporin antibiotic.{48055,48056} It inhibits the growth of various Gram-positive and Gram-negative bacteria, including several strains of S. pyogenes, S. aureus, C. tetani, N. gonorrhoeae, Salmonella, and Shigella (MICs = 0.1-0.2, 0.312-0.625, 0.078, 1.25, 1.56-6.25, and 3.12-12.5 μg/ml, respectively).{48055} Cefalothin binds to E. coli penicillin-binding proteins (PBPs; IC50s = S. pyogenes, D. pneumoniae, and S. aureus.{48055} Formulations containing cefalothin were previously used in the prophylaxis and treatment of bacterial infections.
Brand:CaymanSKU:26063 - 500 mgAvailable on backorder
Cefamandole is a cephalosporin antibiotic that is effective against E. coli (MIC values range from 0.25-2 mg/L depending on strain) as well as H. influenza, S. pneumoniae, and S. aureus.{26293,29387} It has been used to study the expression and inhibition of penicillin-binding proteins on bacterial cell walls and to study antibiotic resistance.{26293}
Brand:CaymanSKU:-Available on backorder
Cefamandole is a cephalosporin antibiotic that is effective against E. coli (MIC values range from 0.25-2 mg/L depending on strain) as well as H. influenza, S. pneumoniae, and S. aureus.{26293,29387} It has been used to study the expression and inhibition of penicillin-binding proteins on bacterial cell walls and to study antibiotic resistance.{26293}
Brand:CaymanSKU:-Available on backorder
Cefamandole is a cephalosporin antibiotic that is effective against E. coli (MIC values range from 0.25-2 mg/L depending on strain) as well as H. influenza, S. pneumoniae, and S. aureus.{26293,29387} It has been used to study the expression and inhibition of penicillin-binding proteins on bacterial cell walls and to study antibiotic resistance.{26293}
Brand:CaymanSKU:-Available on backorder
Cefamandole is a cephalosporin antibiotic that is effective against E. coli (MIC values range from 0.25-2 mg/L depending on strain) as well as H. influenza, S. pneumoniae, and S. aureus.{26293,29387} It has been used to study the expression and inhibition of penicillin-binding proteins on bacterial cell walls and to study antibiotic resistance.{26293}
Brand:CaymanSKU:-Available on backorder
Cefamandole nafate is a formate ester prodrug form of the cephalosporin antibiotic cefamandole (Item No. 18138).{43407} Cefamandole nafate inhibits the growth of E. cloacae, E. coli, K. pneumoniae, P. mirabilis, P. vulgaris, P. morganii, S. aureus, and S. pyogenes in vitro (MICs = 0.1-50 μg/ml). In vivo, cefamanadole nafate protects against E. cloacae, E. coli, K. pneumoniae, P. mirabilis, P. vulgaris, P. morganii, S. aureus, and S. pyogenes infection in mice (ED50s = 0.3-334 mg/kg). Cefamandole (500 mg/kg) also protects against nephrotoxicity induced by the aminoglycoside antibiotic tobramycin (Item No. 14596) in rats.{43408}
Brand:CaymanSKU:23988 - 1 gAvailable on backorder
Cefamandole nafate is a formate ester prodrug form of the cephalosporin antibiotic cefamandole (Item No. 18138).{43407} Cefamandole nafate inhibits the growth of E. cloacae, E. coli, K. pneumoniae, P. mirabilis, P. vulgaris, P. morganii, S. aureus, and S. pyogenes in vitro (MICs = 0.1-50 μg/ml). In vivo, cefamanadole nafate protects against E. cloacae, E. coli, K. pneumoniae, P. mirabilis, P. vulgaris, P. morganii, S. aureus, and S. pyogenes infection in mice (ED50s = 0.3-334 mg/kg). Cefamandole (500 mg/kg) also protects against nephrotoxicity induced by the aminoglycoside antibiotic tobramycin (Item No. 14596) in rats.{43408}
Brand:CaymanSKU:23988 - 5 gAvailable on backorder
Cefamandole nafate is a formate ester prodrug form of the cephalosporin antibiotic cefamandole (Item No. 18138).{43407} Cefamandole nafate inhibits the growth of E. cloacae, E. coli, K. pneumoniae, P. mirabilis, P. vulgaris, P. morganii, S. aureus, and S. pyogenes in vitro (MICs = 0.1-50 μg/ml). In vivo, cefamanadole nafate protects against E. cloacae, E. coli, K. pneumoniae, P. mirabilis, P. vulgaris, P. morganii, S. aureus, and S. pyogenes infection in mice (ED50s = 0.3-334 mg/kg). Cefamandole (500 mg/kg) also protects against nephrotoxicity induced by the aminoglycoside antibiotic tobramycin (Item No. 14596) in rats.{43408}
Brand:CaymanSKU:23988 - 500 mgAvailable on backorder
Cefapirin is a first generation cephalosporin antibiotic that is broadly effective against gram-negative and gram-positive bacteria.{28405,28406} The bactericidal action of cefapirin results from inhibition of cell-wall synthesis, mediated by its binding to penicillin binding proteins. It is mainly used in veterinary medicine for intramammary treatment of mastitis and intrauterine treatment of endometritis in cattle.{28405,28406}
Brand:CaymanSKU:-Available on backorder
Cefapirin is a first generation cephalosporin antibiotic that is broadly effective against gram-negative and gram-positive bacteria.{28405,28406} The bactericidal action of cefapirin results from inhibition of cell-wall synthesis, mediated by its binding to penicillin binding proteins. It is mainly used in veterinary medicine for intramammary treatment of mastitis and intrauterine treatment of endometritis in cattle.{28405,28406}
Brand:CaymanSKU:-Available on backorder
Cefapirin is a first generation cephalosporin antibiotic that is broadly effective against gram-negative and gram-positive bacteria.{28405,28406} The bactericidal action of cefapirin results from inhibition of cell-wall synthesis, mediated by its binding to penicillin binding proteins. It is mainly used in veterinary medicine for intramammary treatment of mastitis and intrauterine treatment of endometritis in cattle.{28405,28406}
Brand:CaymanSKU:-Available on backorder
Cefapirin is a first generation cephalosporin antibiotic that is broadly effective against gram-negative and gram-positive bacteria.{28405,28406} The bactericidal action of cefapirin results from inhibition of cell-wall synthesis, mediated by its binding to penicillin binding proteins. It is mainly used in veterinary medicine for intramammary treatment of mastitis and intrauterine treatment of endometritis in cattle.{28405,28406}
Brand:CaymanSKU:-Available on backorder
Cefazolin is a broad-spectrum cephalosporin antibiotic that is active in vitro against various Gram-positive and Gram-negative bacteria (MICs = 0.2-12.5 μg/ml).{25759} It also inhibits the growth of clinical isolates of S. aureus, E. coli, P. mirabilis, and K. pneumoniae (MICs = 0.1-25 μg/ml). In vivo, cefazolin protects against S. aureus, E. coli, and P. mirabilis infection in mice (ED50s = <0.09-1.78, 0.44-3.63, and 2.31-5.2 mg/animal, respectively). Formulations containing cefazolin have been used to treat a variety of bacterial infections.
Brand:CaymanSKU:- Cefazolin is a broad-spectrum cephalosporin antibiotic that is active in vitro against various Gram-positive and Gram-negative bacteria (MICs = 0.2-12.5 μg/ml).{25759} It also inhibits the growth of clinical isolates of S. aureus, E. coli, P. mirabilis, and K. pneumoniae (MICs = 0.1-25 μg/ml). In vivo, cefazolin protects against S. aureus, E. coli, and P. mirabilis infection in mice (ED50s = <0.09-1.78, 0.44-3.63, and 2.31-5.2 mg/animal, respectively). Formulations containing cefazolin have been used to treat a variety of bacterial infections.
Brand:CaymanSKU:- Cefazolin is a broad-spectrum cephalosporin antibiotic that is active in vitro against various Gram-positive and Gram-negative bacteria (MICs = 0.2-12.5 μg/ml).{25759} It also inhibits the growth of clinical isolates of S. aureus, E. coli, P. mirabilis, and K. pneumoniae (MICs = 0.1-25 μg/ml). In vivo, cefazolin protects against S. aureus, E. coli, and P. mirabilis infection in mice (ED50s = <0.09-1.78, 0.44-3.63, and 2.31-5.2 mg/animal, respectively). Formulations containing cefazolin have been used to treat a variety of bacterial infections.
Brand:CaymanSKU:- Cefazolin is a broad-spectrum cephalosporin antibiotic that is active in vitro against various Gram-positive and Gram-negative bacteria (MICs = 0.2-12.5 μg/ml).{25759} It also inhibits the growth of clinical isolates of S. aureus, E. coli, P. mirabilis, and K. pneumoniae (MICs = 0.1-25 μg/ml). In vivo, cefazolin protects against S. aureus, E. coli, and P. mirabilis infection in mice (ED50s = <0.09-1.78, 0.44-3.63, and 2.31-5.2 mg/animal, respectively). Formulations containing cefazolin have been used to treat a variety of bacterial infections.
Brand:CaymanSKU:-
Cefazolin-13C2,15N is intended for use as an internal standard for the quantification of cefazolin (Item No. 15776) by GC- or LC-MS. Cefazolin is a broad-spectrum cephalosporin antibiotic that is active in vitro against various Gram-positive and Gram-negative bacteria (MICs = 0.2-12.5 μg/ml).{25759} It also inhibits the growth of clinical isolates of S. aureus, E. coli, P. mirabilis, and K. pneumoniae (MICs = 0.1-25 µg/ml). In vivo, cefazolin protects against S. aureus, E. coli, and P. mirabilis infection in mice (ED50s = <0.09-1.78, 0.44-3.63, and 2.31-5.2 mg/animal, respectively). Formulations containing cefazolin have been used to treat a variety of bacterial infections.
Brand:CaymanSKU:25319 - 1 mgAvailable on backorder
Cefdinir is a broad-spectrum β-lactam antibiotic of the cephalosporin class that inhibits cell wall synthesis in Gram-positive and Gram-negative bacteria.{33830} Formulations containing cefdinir are used for bacterial infections of the respiratory system, ear, throat, and skin.{33829} Children with severe acute malnutrition treated with a formulation containing cefnidir (14 mg/kg twice daily for seven days) had a 90.9% recovery rate and a significantly reduced mortality rate.{33831}
Brand:CaymanSKU:21521 -Out of stock
Cefdinir is a broad-spectrum β-lactam antibiotic of the cephalosporin class that inhibits cell wall synthesis in Gram-positive and Gram-negative bacteria.{33830} Formulations containing cefdinir are used for bacterial infections of the respiratory system, ear, throat, and skin.{33829} Children with severe acute malnutrition treated with a formulation containing cefnidir (14 mg/kg twice daily for seven days) had a 90.9% recovery rate and a significantly reduced mortality rate.{33831}
Brand:CaymanSKU:21521 -Out of stock
Cefdinir is a broad-spectrum β-lactam antibiotic of the cephalosporin class that inhibits cell wall synthesis in Gram-positive and Gram-negative bacteria.{33830} Formulations containing cefdinir are used for bacterial infections of the respiratory system, ear, throat, and skin.{33829} Children with severe acute malnutrition treated with a formulation containing cefnidir (14 mg/kg twice daily for seven days) had a 90.9% recovery rate and a significantly reduced mortality rate.{33831}
Brand:CaymanSKU:21521 -Out of stock
Cefditoren pivoxil is an orally bioavailable prodrug form of the broad-spectrum cephalosporin antibiotic cefditoren.{53674} Cefditoren pivoxil is hydrolyzed by intestinal wall esterases to form cefditoren. Cefditoren pivoxil is effective against systemic S. aureus, E. coli, K. pneumoniae, P. mirabilis, or S. marcescens infections in mice with ED50 values of 10, 2.5, 11, 4.4, and 11 mg/kg, respectively.{53675} Formulations containing cefditoren pivoxil were previously used in the treatment of acute bacterial exacerbations of chronic bronchitis and community-acquired pneumonia.
Brand:CaymanSKU:30315 - 10 mgAvailable on backorder
Cefditoren pivoxil is an orally bioavailable prodrug form of the broad-spectrum cephalosporin antibiotic cefditoren.{53674} Cefditoren pivoxil is hydrolyzed by intestinal wall esterases to form cefditoren. Cefditoren pivoxil is effective against systemic S. aureus, E. coli, K. pneumoniae, P. mirabilis, or S. marcescens infections in mice with ED50 values of 10, 2.5, 11, 4.4, and 11 mg/kg, respectively.{53675} Formulations containing cefditoren pivoxil were previously used in the treatment of acute bacterial exacerbations of chronic bronchitis and community-acquired pneumonia.
Brand:CaymanSKU:30315 - 100 mgAvailable on backorder
Cefditoren pivoxil is an orally bioavailable prodrug form of the broad-spectrum cephalosporin antibiotic cefditoren.{53674} Cefditoren pivoxil is hydrolyzed by intestinal wall esterases to form cefditoren. Cefditoren pivoxil is effective against systemic S. aureus, E. coli, K. pneumoniae, P. mirabilis, or S. marcescens infections in mice with ED50 values of 10, 2.5, 11, 4.4, and 11 mg/kg, respectively.{53675} Formulations containing cefditoren pivoxil were previously used in the treatment of acute bacterial exacerbations of chronic bronchitis and community-acquired pneumonia.
Brand:CaymanSKU:30315 - 5 mgAvailable on backorder
Cefditoren pivoxil is an orally bioavailable prodrug form of the broad-spectrum cephalosporin antibiotic cefditoren.{53674} Cefditoren pivoxil is hydrolyzed by intestinal wall esterases to form cefditoren. Cefditoren pivoxil is effective against systemic S. aureus, E. coli, K. pneumoniae, P. mirabilis, or S. marcescens infections in mice with ED50 values of 10, 2.5, 11, 4.4, and 11 mg/kg, respectively.{53675} Formulations containing cefditoren pivoxil were previously used in the treatment of acute bacterial exacerbations of chronic bronchitis and community-acquired pneumonia.
Brand:CaymanSKU:30315 - 50 mgAvailable on backorder
Cefepime is a broad-spectrum cephalosporin antibiotic that inhibits the growth of Gram-positive and Gram-negative bacteria.{38779,38780} It inhibits the growth of some clinical isolates of Corynebacterium, Streptococcus, and Staphylococcus (MIC90s = 0.03-8 μg/ml), but does not inhibit the growth of methicillin-resistant S. aureus (MRSA) or S. haemolyticus (MIC50s = >128 μg/ml).{38779} Cefepime inhibits the growth of some Citrobacter, Enterobacter, Klebsiella, Salmonella, Serratia, Shigella, and enteric bacilli species in addition to P. mirabilis and E. coli clinical isolates (MIC90s = ≤0.12-2 μg/ml).{38780} It also inhibits the growth of E. coli and Klebsiella strains that produce extended-spectrum β-lactamase (ESBL; MIC90s = 4 and 8 μg/mL, respectively) and of indole-positive Proteae (MIC90 = 0.25 μg/ml). Cefepime inhibits the growth of pneumococci strains (MICs = 0.5-2 mg/l) in vitro and in vivo in a mouse model of peritonitis (ED50s = 0.6-1.14 mg/kg).{38781} Formulations containing cefepime have been used in the treatment of a variety of bacterial infections.
Brand:CaymanSKU:23633 - 1 gAvailable on backorder
Cefepime is a broad-spectrum cephalosporin antibiotic that inhibits the growth of Gram-positive and Gram-negative bacteria.{38779,38780} It inhibits the growth of some clinical isolates of Corynebacterium, Streptococcus, and Staphylococcus (MIC90s = 0.03-8 μg/ml), but does not inhibit the growth of methicillin-resistant S. aureus (MRSA) or S. haemolyticus (MIC50s = >128 μg/ml).{38779} Cefepime inhibits the growth of some Citrobacter, Enterobacter, Klebsiella, Salmonella, Serratia, Shigella, and enteric bacilli species in addition to P. mirabilis and E. coli clinical isolates (MIC90s = ≤0.12-2 μg/ml).{38780} It also inhibits the growth of E. coli and Klebsiella strains that produce extended-spectrum β-lactamase (ESBL; MIC90s = 4 and 8 μg/mL, respectively) and of indole-positive Proteae (MIC90 = 0.25 μg/ml). Cefepime inhibits the growth of pneumococci strains (MICs = 0.5-2 mg/l) in vitro and in vivo in a mouse model of peritonitis (ED50s = 0.6-1.14 mg/kg).{38781} Formulations containing cefepime have been used in the treatment of a variety of bacterial infections.
Brand:CaymanSKU:23633 - 250 mgAvailable on backorder
Cefepime is a broad-spectrum cephalosporin antibiotic that inhibits the growth of Gram-positive and Gram-negative bacteria.{38779,38780} It inhibits the growth of some clinical isolates of Corynebacterium, Streptococcus, and Staphylococcus (MIC90s = 0.03-8 μg/ml), but does not inhibit the growth of methicillin-resistant S. aureus (MRSA) or S. haemolyticus (MIC50s = >128 μg/ml).{38779} Cefepime inhibits the growth of some Citrobacter, Enterobacter, Klebsiella, Salmonella, Serratia, Shigella, and enteric bacilli species in addition to P. mirabilis and E. coli clinical isolates (MIC90s = ≤0.12-2 μg/ml).{38780} It also inhibits the growth of E. coli and Klebsiella strains that produce extended-spectrum β-lactamase (ESBL; MIC90s = 4 and 8 μg/mL, respectively) and of indole-positive Proteae (MIC90 = 0.25 μg/ml). Cefepime inhibits the growth of pneumococci strains (MICs = 0.5-2 mg/l) in vitro and in vivo in a mouse model of peritonitis (ED50s = 0.6-1.14 mg/kg).{38781} Formulations containing cefepime have been used in the treatment of a variety of bacterial infections.
Brand:CaymanSKU:23633 - 5 gAvailable on backorder
Cefepime is a broad-spectrum cephalosporin antibiotic that inhibits the growth of Gram-positive and Gram-negative bacteria.{38779,38780} It inhibits the growth of some clinical isolates of Corynebacterium, Streptococcus, and Staphylococcus (MIC90s = 0.03-8 μg/ml), but does not inhibit the growth of methicillin-resistant S. aureus (MRSA) or S. haemolyticus (MIC50s = >128 μg/ml).{38779} Cefepime inhibits the growth of some Citrobacter, Enterobacter, Klebsiella, Salmonella, Serratia, Shigella, and enteric bacilli species in addition to P. mirabilis and E. coli clinical isolates (MIC90s = ≤0.12-2 μg/ml).{38780} It also inhibits the growth of E. coli and Klebsiella strains that produce extended-spectrum β-lactamase (ESBL; MIC90s = 4 and 8 μg/mL, respectively) and of indole-positive Proteae (MIC90 = 0.25 μg/ml). Cefepime inhibits the growth of pneumococci strains (MICs = 0.5-2 mg/l) in vitro and in vivo in a mouse model of peritonitis (ED50s = 0.6-1.14 mg/kg).{38781} Formulations containing cefepime have been used in the treatment of a variety of bacterial infections.
Brand:CaymanSKU:23633 - 500 mgAvailable on backorder
Cefixime is a third generation cephalosporin antibiotic. It is effective against a variety of Gram-negative bacteria, including E. coli, K. pneumoniae, and H. influenzae (MIC values range from <0.025 to 25 µg/ml).{28223} Cefixime binds penicillin-binding proteins and is stable to many penicillinases and β-lactamases.{28221,28225} It is an effective, orally-active cephalosporin with applications in acute otitis media, respiratory tract infections, and urinary tract infections.{28222,28224}
Brand:CaymanSKU:-Out of stock
Cefixime is a third generation cephalosporin antibiotic. It is effective against a variety of Gram-negative bacteria, including E. coli, K. pneumoniae, and H. influenzae (MIC values range from <0.025 to 25 µg/ml).{28223} Cefixime binds penicillin-binding proteins and is stable to many penicillinases and β-lactamases.{28221,28225} It is an effective, orally-active cephalosporin with applications in acute otitis media, respiratory tract infections, and urinary tract infections.{28222,28224}
Brand:CaymanSKU:-Out of stock
Cefixime is a third generation cephalosporin antibiotic. It is effective against a variety of Gram-negative bacteria, including E. coli, K. pneumoniae, and H. influenzae (MIC values range from <0.025 to 25 µg/ml).{28223} Cefixime binds penicillin-binding proteins and is stable to many penicillinases and β-lactamases.{28221,28225} It is an effective, orally-active cephalosporin with applications in acute otitis media, respiratory tract infections, and urinary tract infections.{28222,28224}
Brand:CaymanSKU:-Out of stock
Cefixime is a third generation cephalosporin antibiotic. It is effective against a variety of Gram-negative bacteria, including E. coli, K. pneumoniae, and H. influenzae (MIC values range from <0.025 to 25 µg/ml).{28223} Cefixime binds penicillin-binding proteins and is stable to many penicillinases and β-lactamases.{28221,28225} It is an effective, orally-active cephalosporin with applications in acute otitis media, respiratory tract infections, and urinary tract infections.{28222,28224}
Brand:CaymanSKU:-Out of stock
Cefmenoxime is a broad-spectrum cephalosporin antibiotic.{45158} It is active against clinical isolates of S. aureus, S. epidermidis, S. pyogenes, E. coli, K. pneumoniae, P. mirabilis, P. vulgaris, P. morganii, S. marcescens, and E. cloacae in vitro (MICs = 0.013-6.25 μg/ml). It is active against various Gram-positive and Gram-negative bacterial infections in mice (ED50s = 0.016-66 mg/kg). It increases survival in a mouse model of K. pneumoniae infection with a 50% survival dose (SD50) value of 7.6 mg/kg. Cefmenoxime is curative in a mouse model of P. mirabilis urinary tract infection with curative dose (CD50) values ranging from 0.4 to 0.75 mg/kg. Formulations containing cefmenoxime have been used to treat various bacterial infections.
Brand:CaymanSKU:26440 - 1 gAvailable on backorder
Cefmenoxime is a broad-spectrum cephalosporin antibiotic.{45158} It is active against clinical isolates of S. aureus, S. epidermidis, S. pyogenes, E. coli, K. pneumoniae, P. mirabilis, P. vulgaris, P. morganii, S. marcescens, and E. cloacae in vitro (MICs = 0.013-6.25 μg/ml). It is active against various Gram-positive and Gram-negative bacterial infections in mice (ED50s = 0.016-66 mg/kg). It increases survival in a mouse model of K. pneumoniae infection with a 50% survival dose (SD50) value of 7.6 mg/kg. Cefmenoxime is curative in a mouse model of P. mirabilis urinary tract infection with curative dose (CD50) values ranging from 0.4 to 0.75 mg/kg. Formulations containing cefmenoxime have been used to treat various bacterial infections.
Brand:CaymanSKU:26440 - 100 mgAvailable on backorder
Cefmenoxime is a broad-spectrum cephalosporin antibiotic.{45158} It is active against clinical isolates of S. aureus, S. epidermidis, S. pyogenes, E. coli, K. pneumoniae, P. mirabilis, P. vulgaris, P. morganii, S. marcescens, and E. cloacae in vitro (MICs = 0.013-6.25 μg/ml). It is active against various Gram-positive and Gram-negative bacterial infections in mice (ED50s = 0.016-66 mg/kg). It increases survival in a mouse model of K. pneumoniae infection with a 50% survival dose (SD50) value of 7.6 mg/kg. Cefmenoxime is curative in a mouse model of P. mirabilis urinary tract infection with curative dose (CD50) values ranging from 0.4 to 0.75 mg/kg. Formulations containing cefmenoxime have been used to treat various bacterial infections.
Brand:CaymanSKU:26440 - 50 mgAvailable on backorder
Cefmenoxime is a broad-spectrum cephalosporin antibiotic.{45158} It is active against clinical isolates of S. aureus, S. epidermidis, S. pyogenes, E. coli, K. pneumoniae, P. mirabilis, P. vulgaris, P. morganii, S. marcescens, and E. cloacae in vitro (MICs = 0.013-6.25 μg/ml). It is active against various Gram-positive and Gram-negative bacterial infections in mice (ED50s = 0.016-66 mg/kg). It increases survival in a mouse model of K. pneumoniae infection with a 50% survival dose (SD50) value of 7.6 mg/kg. Cefmenoxime is curative in a mouse model of P. mirabilis urinary tract infection with curative dose (CD50) values ranging from 0.4 to 0.75 mg/kg. Formulations containing cefmenoxime have been used to treat various bacterial infections.
Brand:CaymanSKU:26440 - 500 mgAvailable on backorder
Cefmetazole is a cephamycin antibiotic.{55066} It is active against E. coli, P. mirabilis, H. influenzae, N. gonorrhoeae, S. pneumoniae, and S. pyogenes (MIC50s = 0.25-2 μg/ml). Cefmetazole (20 and 40 mg/kg per day) decreases the lesion size and the number of ulcerative lesions in a rabbit model of active syphilis.{55067}
Brand:CaymanSKU:30269 - 10 mgAvailable on backorder
Cefmetazole is a cephamycin antibiotic.{55066} It is active against E. coli, P. mirabilis, H. influenzae, N. gonorrhoeae, S. pneumoniae, and S. pyogenes (MIC50s = 0.25-2 μg/ml). Cefmetazole (20 and 40 mg/kg per day) decreases the lesion size and the number of ulcerative lesions in a rabbit model of active syphilis.{55067}
Brand:CaymanSKU:30269 - 100 mgAvailable on backorder
Cefmetazole is a cephamycin antibiotic.{55066} It is active against E. coli, P. mirabilis, H. influenzae, N. gonorrhoeae, S. pneumoniae, and S. pyogenes (MIC50s = 0.25-2 μg/ml). Cefmetazole (20 and 40 mg/kg per day) decreases the lesion size and the number of ulcerative lesions in a rabbit model of active syphilis.{55067}
Brand:CaymanSKU:30269 - 25 mgAvailable on backorder
Cefmetazole is a cephamycin antibiotic.{55066} It is active against E. coli, P. mirabilis, H. influenzae, N. gonorrhoeae, S. pneumoniae, and S. pyogenes (MIC50s = 0.25-2 μg/ml). Cefmetazole (20 and 40 mg/kg per day) decreases the lesion size and the number of ulcerative lesions in a rabbit model of active syphilis.{55067}
Brand:CaymanSKU:30269 - 50 mgAvailable on backorder
Cefonicid is a second-generation cephalosporin antibiotic.{29387} Like other cephalosporins, cefonicid interferes with cell wall biosynthesis in bacteria, leading to lysis of the infectious organism. It is a broad-spectrum antibiotic and has a prolonged serum elimination half-life in animals.{29387}
Brand:CaymanSKU:-Available on backorder
Cefonicid is a second-generation cephalosporin antibiotic.{29387} Like other cephalosporins, cefonicid interferes with cell wall biosynthesis in bacteria, leading to lysis of the infectious organism. It is a broad-spectrum antibiotic and has a prolonged serum elimination half-life in animals.{29387}
Brand:CaymanSKU:-Available on backorder
Cefonicid is a second-generation cephalosporin antibiotic.{29387} Like other cephalosporins, cefonicid interferes with cell wall biosynthesis in bacteria, leading to lysis of the infectious organism. It is a broad-spectrum antibiotic and has a prolonged serum elimination half-life in animals.{29387}
Brand:CaymanSKU:-Available on backorder
Cefoperazone is a cephalosporin antibiotic that is active in vitro against most Gram-positive and Gram-negative bacteria, including β-lactamase strains (3-4 µg/ml inhibits 90% of S. aureus growth).{25856} It has been studied in the treatment of upper and lower respiratory tract infections, urinary tract infections, gynecological infections, skin infections, as well as bacteremia.{25856}
Brand:CaymanSKU:- Cefoperazone is a cephalosporin antibiotic that is active in vitro against most Gram-positive and Gram-negative bacteria, including β-lactamase strains (3-4 µg/ml inhibits 90% of S. aureus growth).{25856} It has been studied in the treatment of upper and lower respiratory tract infections, urinary tract infections, gynecological infections, skin infections, as well as bacteremia.{25856}
Brand:CaymanSKU:- Cefoperazone is a cephalosporin antibiotic that is active in vitro against most Gram-positive and Gram-negative bacteria, including β-lactamase strains (3-4 µg/ml inhibits 90% of S. aureus growth).{25856} It has been studied in the treatment of upper and lower respiratory tract infections, urinary tract infections, gynecological infections, skin infections, as well as bacteremia.{25856}
Brand:CaymanSKU:-
Cefotaxime is a cephalosporin antibiotic with potent in vitro activity against streptococcal species, including S. aureus (IC50 = 2 µg/ml) and penicillin-resistant S. pneumoniae.{25856} It is also effective against a wide range of other β-lactamase-producing bacterial species (MIC90s = 0.01 – 130 µg/ml).{25856} Cefotaxime acts by interfering with bacterial cell wall synthesis and has also been shown to be a competitive inhibitor of β-lactamase.{25971}
Brand:CaymanSKU:- Cefotaxime is a cephalosporin antibiotic with potent in vitro activity against streptococcal species, including S. aureus (IC50 = 2 µg/ml) and penicillin-resistant S. pneumoniae.{25856} It is also effective against a wide range of other β-lactamase-producing bacterial species (MIC90s = 0.01 – 130 µg/ml).{25856} Cefotaxime acts by interfering with bacterial cell wall synthesis and has also been shown to be a competitive inhibitor of β-lactamase.{25971}
Brand:CaymanSKU:- Cefotaxime is a cephalosporin antibiotic with potent in vitro activity against streptococcal species, including S. aureus (IC50 = 2 µg/ml) and penicillin-resistant S. pneumoniae.{25856} It is also effective against a wide range of other β-lactamase-producing bacterial species (MIC90s = 0.01 – 130 µg/ml).{25856} Cefotaxime acts by interfering with bacterial cell wall synthesis and has also been shown to be a competitive inhibitor of β-lactamase.{25971}
Brand:CaymanSKU:- Cefotaxime is a cephalosporin antibiotic with potent in vitro activity against streptococcal species, including S. aureus (IC50 = 2 µg/ml) and penicillin-resistant S. pneumoniae.{25856} It is also effective against a wide range of other β-lactamase-producing bacterial species (MIC90s = 0.01 – 130 µg/ml).{25856} Cefotaxime acts by interfering with bacterial cell wall synthesis and has also been shown to be a competitive inhibitor of β-lactamase.{25971}
Brand:CaymanSKU:-
Cefotetan is a cephamycin antibiotic that is active against both Gram-positive and Gram-negative bacteria including isolates of E. coli, S. aureus, K. pneumoniae, and P. maltophilia (MICs = 0.03-32 mg/ml).{36577} It reduces mortality by 50% in a rabbit model of fecal peritonitis when administered at a dose of 25 mg/kg twice daily.{36578} Formulations containing cefotetan have been used in the treatment of various bacterial infections.
Brand:CaymanSKU:23624 - 100 mgAvailable on backorder
Cefotetan is a cephamycin antibiotic that is active against both Gram-positive and Gram-negative bacteria including isolates of E. coli, S. aureus, K. pneumoniae, and P. maltophilia (MICs = 0.03-32 mg/ml).{36577} It reduces mortality by 50% in a rabbit model of fecal peritonitis when administered at a dose of 25 mg/kg twice daily.{36578} Formulations containing cefotetan have been used in the treatment of various bacterial infections.
Brand:CaymanSKU:23624 - 250 mgAvailable on backorder
Cefotetan is a cephamycin antibiotic that is active against both Gram-positive and Gram-negative bacteria including isolates of E. coli, S. aureus, K. pneumoniae, and P. maltophilia (MICs = 0.03-32 mg/ml).{36577} It reduces mortality by 50% in a rabbit model of fecal peritonitis when administered at a dose of 25 mg/kg twice daily.{36578} Formulations containing cefotetan have been used in the treatment of various bacterial infections.
Brand:CaymanSKU:23624 - 50 mgAvailable on backorder
Cefoxitin is a second generation cephalosporin antibiotic that has been used to treat a wide range of gram-negative and gram-positive bacteria including anaerobes.{25972} It acts by interfering with bacterial cell wall synthesis and has also been shown to induce β-lactamase synthesis.{25971}
Brand:CaymanSKU:- Cefoxitin is a second generation cephalosporin antibiotic that has been used to treat a wide range of gram-negative and gram-positive bacteria including anaerobes.{25972} It acts by interfering with bacterial cell wall synthesis and has also been shown to induce β-lactamase synthesis.{25971}
Brand:CaymanSKU:-