Chemicals
Showing 5701–5850 of 41137 results
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4-Bromoamphetamine is a para-substituted amphetamine that acts as a monoamine releasing agent.{25537,25538} It is highly neurotoxic, producing long-term depletion of serotonin.{25537,25538} This product is intended only for forensic and research purposes.
Brand:CaymanSKU:9001850 - 10 mgAvailable on backorder
4-Bromoamphetamine is a para-substituted amphetamine that acts as a monoamine releasing agent.{25537,25538} It is highly neurotoxic, producing long-term depletion of serotonin.{25537,25538} This product is intended only for forensic and research purposes.
Brand:CaymanSKU:9001850 - 5 mgAvailable on backorder
4-Bromoamphetamine is a para-substituted amphetamine that acts as a monoamine releasing agent.{25537,25538} It is highly neurotoxic, producing long-term depletion of serotonin.{25537,25538} This product is intended only for forensic and research purposes.
Brand:CaymanSKU:9001850 - 50 mgAvailable on backorder
4-Bromoethcathinone (hydrochloride) (Item No. 17395) is an analytical reference standard that is structurally categorized as a cathinone. The physiological and toxicological properties of this compound are not known. This product is intended for research and forensic applications.
Brand:CaymanSKU:-Available on backorder
4-Bromoethcathinone (hydrochloride) (Item No. 17395) is an analytical reference standard that is structurally categorized as a cathinone. The physiological and toxicological properties of this compound are not known. This product is intended for research and forensic applications.
Brand:CaymanSKU:-Available on backorder
4-CAB is an analog of p-chloroamphetamine, a psychoactive compound which shows pronounced toxicity for serotonergic neurons.{22305,21515} 4-CAB inhibits the reuptake of serotonin (IC50 = 330 nM) and dopamine (IC50 = 2.3 μM).{22305} This product is intended for forensic and research applications.
Brand:CaymanSKU:-4-CAB is an analog of p-chloroamphetamine, a psychoactive compound which shows pronounced toxicity for serotonergic neurons.{22305,21515} 4-CAB inhibits the reuptake of serotonin (IC50 = 330 nM) and dopamine (IC50 = 2.3 μM).{22305} This product is intended for forensic and research applications.
Brand:CaymanSKU:-4-CAB is an analog of p-chloroamphetamine, a psychoactive compound which shows pronounced toxicity for serotonergic neurons.{22305,21515} 4-CAB inhibits the reuptake of serotonin (IC50 = 330 nM) and dopamine (IC50 = 2.3 μM).{22305} This product is intended for forensic and research applications.
Brand:CaymanSKU:-4-carboxy TEMPO is a nitroxide and spin label.{40632} Nitroxides such as 4-carboxy TEMPO react with reactive oxygen species (ROS) and can be used with electron spin resonance (ESR) spectroscopy to monitor ROS production in vivo.{40632},{40634} It has also been used to study flavin-photosensitized damage in inner mitochondrial membranes.{40633}
Brand:CaymanSKU:23139 - 100 mgAvailable on backorder
4-carboxy TEMPO is a nitroxide and spin label.{40632} Nitroxides such as 4-carboxy TEMPO react with reactive oxygen species (ROS) and can be used with electron spin resonance (ESR) spectroscopy to monitor ROS production in vivo.{40632},{40634} It has also been used to study flavin-photosensitized damage in inner mitochondrial membranes.{40633}
Brand:CaymanSKU:23139 - 250 mgAvailable on backorder
4-carboxy TEMPO is a nitroxide and spin label.{40632} Nitroxides such as 4-carboxy TEMPO react with reactive oxygen species (ROS) and can be used with electron spin resonance (ESR) spectroscopy to monitor ROS production in vivo.{40632},{40634} It has also been used to study flavin-photosensitized damage in inner mitochondrial membranes.{40633}
Brand:CaymanSKU:23139 - 50 mgAvailable on backorder
4-carboxy TEMPO is a nitroxide and spin label.{40632} Nitroxides such as 4-carboxy TEMPO react with reactive oxygen species (ROS) and can be used with electron spin resonance (ESR) spectroscopy to monitor ROS production in vivo.{40632},{40634} It has also been used to study flavin-photosensitized damage in inner mitochondrial membranes.{40633}
Brand:CaymanSKU:23139 - 500 mgAvailable on backorder
4-chloro CUMYL-PINACA (Item No. 26132) is an analytical reference standard that is structurally similar to known synthetic cannabinoids. This product is intended for research and forensic applications.
Brand:CaymanSKU:26132 - 1 mgAvailable on backorder
4-chloro CUMYL-PINACA (Item No. 26132) is an analytical reference standard that is structurally similar to known synthetic cannabinoids. This product is intended for research and forensic applications.
Brand:CaymanSKU:26132 - 5 mgAvailable on backorder
2,5-Dimethoxyamphetamine (2,5-DMA) (Item No. 9001314) and its 4-substituted analogs are designer drugs which activate the serotonin 5-HT2 receptors.{21376,20771,21281} 4-chloro-2,5-Dimethoxyamphetamine (4-chloro-2,5-DMA) is an analog of 2,5-DMA which can be found on the illicit drug market.{20771} Its physiological and toxicological properties are poorly understood. This product is intended for research and forensic applications.
Brand:CaymanSKU:12038 - 1 mgAvailable on backorder
2,5-Dimethoxyamphetamine (2,5-DMA) (Item No. 9001314) and its 4-substituted analogs are designer drugs which activate the serotonin 5-HT2 receptors.{21376,20771,21281} 4-chloro-2,5-Dimethoxyamphetamine (4-chloro-2,5-DMA) is an analog of 2,5-DMA which can be found on the illicit drug market.{20771} Its physiological and toxicological properties are poorly understood. This product is intended for research and forensic applications.
Brand:CaymanSKU:12038 - 10 mgAvailable on backorder
2,5-Dimethoxyamphetamine (2,5-DMA) (Item No. 9001314) and its 4-substituted analogs are designer drugs which activate the serotonin 5-HT2 receptors.{21376,20771,21281} 4-chloro-2,5-Dimethoxyamphetamine (4-chloro-2,5-DMA) is an analog of 2,5-DMA which can be found on the illicit drug market.{20771} Its physiological and toxicological properties are poorly understood. This product is intended for research and forensic applications.
Brand:CaymanSKU:12038 - 5 mgAvailable on backorder
4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline is a building block and synthetic intermediate.{24622,54088,54089,54090,54091} It has been used as a precursor in the synthesis of receptor tyrosine kinase (RTK) inhibitors, dual RTK and histone deacetylase (HDAC) inhibitors, and anticancer compounds.{24622,54088,54089} It is also a synthetic intermediate in the synthesis of EGFR inhibitors, including erlotinib (Item No. 10483), with antiproliferative activity.{54090,54091}
Brand:CaymanSKU:30487 - 100 mgAvailable on backorder
4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline is a building block and synthetic intermediate.{24622,54088,54089,54090,54091} It has been used as a precursor in the synthesis of receptor tyrosine kinase (RTK) inhibitors, dual RTK and histone deacetylase (HDAC) inhibitors, and anticancer compounds.{24622,54088,54089} It is also a synthetic intermediate in the synthesis of EGFR inhibitors, including erlotinib (Item No. 10483), with antiproliferative activity.{54090,54091}
Brand:CaymanSKU:30487 - 25 mgAvailable on backorder
4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline is a building block and synthetic intermediate.{24622,54088,54089,54090,54091} It has been used as a precursor in the synthesis of receptor tyrosine kinase (RTK) inhibitors, dual RTK and histone deacetylase (HDAC) inhibitors, and anticancer compounds.{24622,54088,54089} It is also a synthetic intermediate in the synthesis of EGFR inhibitors, including erlotinib (Item No. 10483), with antiproliferative activity.{54090,54091}
Brand:CaymanSKU:30487 - 250 mgAvailable on backorder
4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline is a building block and synthetic intermediate.{24622,54088,54089,54090,54091} It has been used as a precursor in the synthesis of receptor tyrosine kinase (RTK) inhibitors, dual RTK and histone deacetylase (HDAC) inhibitors, and anticancer compounds.{24622,54088,54089} It is also a synthetic intermediate in the synthesis of EGFR inhibitors, including erlotinib (Item No. 10483), with antiproliferative activity.{54090,54091}
Brand:CaymanSKU:30487 - 50 mgAvailable on backorder
4-chloro-α-cyanocinnamic acid (Cl-CCA) is a phenylpropanoid, related to cinnamic acid, which is synthesized by plants from phenylalanine. Cl-CCA readily co-crystallizes with various biomolecules (e.g., peptides, nucleic acids, etc.).
Brand:CaymanSKU:9000981 - 10 mgAvailable on backorder
4-chloro-α-cyanocinnamic acid (Cl-CCA) is a phenylpropanoid, related to cinnamic acid, which is synthesized by plants from phenylalanine. Cl-CCA readily co-crystallizes with various biomolecules (e.g., peptides, nucleic acids, etc.).
Brand:CaymanSKU:9000981 - 25 mgAvailable on backorder
4-chloro-α-cyanocinnamic acid (Cl-CCA) is a phenylpropanoid, related to cinnamic acid, which is synthesized by plants from phenylalanine. Cl-CCA readily co-crystallizes with various biomolecules (e.g., peptides, nucleic acids, etc.).
Brand:CaymanSKU:9000981 - 5 mgAvailable on backorder
4-chloro-α-cyanocinnamic acid (Cl-CCA) is a phenylpropanoid, related to cinnamic acid, which is synthesized by plants from phenylalanine. Cl-CCA readily co-crystallizes with various biomolecules (e.g., peptides, nucleic acids, etc.).
Brand:CaymanSKU:9000981 - 50 mgAvailable on backorder
Halogenated amphetamines, including chloroamphetamines (CAs), are psychostimulatory compounds that have been abused recreationally.{25534} 4-CA is a halogenated amphetamine that causes rapid depletion of serotonin and its major metabolite, 5-hydroxyindoleacetic acid, in animal brains within hours after injection.{25537,25538} In addition, it is highly and selectively neurotoxic, targeting serotonergic neurons.{25537,25538} This product is intended for forensic and research applications.
Brand:CaymanSKU:9001856 - 10 mgAvailable on backorder
Halogenated amphetamines, including chloroamphetamines (CAs), are psychostimulatory compounds that have been abused recreationally.{25534} 4-CA is a halogenated amphetamine that causes rapid depletion of serotonin and its major metabolite, 5-hydroxyindoleacetic acid, in animal brains within hours after injection.{25537,25538} In addition, it is highly and selectively neurotoxic, targeting serotonergic neurons.{25537,25538} This product is intended for forensic and research applications.
Brand:CaymanSKU:9001856 - 5 mgAvailable on backorder
Halogenated amphetamines, including chloroamphetamines (CAs), are psychostimulatory compounds that have been abused recreationally.{25534} 4-CA is a halogenated amphetamine that causes rapid depletion of serotonin and its major metabolite, 5-hydroxyindoleacetic acid, in animal brains within hours after injection.{25537,25538} In addition, it is highly and selectively neurotoxic, targeting serotonergic neurons.{25537,25538} This product is intended for forensic and research applications.
Brand:CaymanSKU:9001856 - 50 mgAvailable on backorder
4-Chlorocathinone (hydrochloride) (Item No. 30379) is an analytical reference standard categorized as a cathinone.{52427} 4-Chlorocathinone produces partial stimulus generalization to (±)-cathinone (Item Nos. 14138 | 15654) in rats. This product is intended for research and forensic applications.
Brand:CaymanSKU:30379 - 1 mgAvailable on backorder
4-Chlorocathinone (hydrochloride) (Item No. 30379) is an analytical reference standard categorized as a cathinone.{52427} 4-Chlorocathinone produces partial stimulus generalization to (±)-cathinone (Item Nos. 14138 | 15654) in rats. This product is intended for research and forensic applications.
Brand:CaymanSKU:30379 - 5 mgAvailable on backorder
Methamphetamine (Item No. 13997) is a regulated psychoactive compound that is both neurotoxic and prone to addiction.{26354,26355,26356} 4-Chloromethamphetamine is a halogenated analog of methamphetamine. In vivo, it is converted to 4-chloroamphetamine (Item No. 9001856), which causes rapid depletion of neurological serotonin within hours after injection.{25537,25538} 4-Chloroampetamine is highly and selectively neurotoxic, targeting serotonergic neurons.{25537,25538} This product is intended for forensic and research applications.
Brand:CaymanSKU:9002185 - 10 mgAvailable on backorder
Methamphetamine (Item No. 13997) is a regulated psychoactive compound that is both neurotoxic and prone to addiction.{26354,26355,26356} 4-Chloromethamphetamine is a halogenated analog of methamphetamine. In vivo, it is converted to 4-chloroamphetamine (Item No. 9001856), which causes rapid depletion of neurological serotonin within hours after injection.{25537,25538} 4-Chloroampetamine is highly and selectively neurotoxic, targeting serotonergic neurons.{25537,25538} This product is intended for forensic and research applications.
Brand:CaymanSKU:9002185 - 5 mgAvailable on backorder
Methamphetamine (Item No. 13997) is a regulated psychoactive compound that is both neurotoxic and prone to addiction.{26354,26355,26356} 4-Chloromethamphetamine is a halogenated analog of methamphetamine. In vivo, it is converted to 4-chloroamphetamine (Item No. 9001856), which causes rapid depletion of neurological serotonin within hours after injection.{25537,25538} 4-Chloroampetamine is highly and selectively neurotoxic, targeting serotonergic neurons.{25537,25538} This product is intended for forensic and research applications.
Brand:CaymanSKU:9002185 - 50 mgAvailable on backorder
4-Chlorophenyl-2-pyridinylmethanol is a synthetic intermediate. It has been used in the synthesis of pharmaceutical compounds, including bepotastine besilate, a non-sedating antihistamine.{34017}
Brand:CaymanSKU:21861 -Out of stock
4-Chlorophenyl-2-pyridinylmethanol is a synthetic intermediate. It has been used in the synthesis of pharmaceutical compounds, including bepotastine besilate, a non-sedating antihistamine.{34017}
Brand:CaymanSKU:21861 -Out of stock
4-Chlorophenyl-2-pyridinylmethanol is a synthetic intermediate. It has been used in the synthesis of pharmaceutical compounds, including bepotastine besilate, a non-sedating antihistamine.{34017}
Brand:CaymanSKU:21861 -Out of stock
4-Chlorophenyl-2-pyridinylmethanol is a synthetic intermediate. It has been used in the synthesis of pharmaceutical compounds, including bepotastine besilate, a non-sedating antihistamine.{34017}
Brand:CaymanSKU:21861 -Out of stock
4-CPPC is an inhibitor of macrophage migration inhibitory factor-2 (MIF-2; IC50 = 27 µM).{46807} It is selective for MIF-2 over MIF-1 (IC50 = 450 µM). It inhibits MIF-2, but not MIF-1, binding to CD74 in vitro when used at a concentration of 10 µM. 4-CPPC (5, 10, and 25 µM) inhibits MIF-2-induced ERK1/2 phosphorylation in primary human skin fibroblasts.
Brand:CaymanSKU:30068 - 1 mgAvailable on backorder
4-CPPC is an inhibitor of macrophage migration inhibitory factor-2 (MIF-2; IC50 = 27 µM).{46807} It is selective for MIF-2 over MIF-1 (IC50 = 450 µM). It inhibits MIF-2, but not MIF-1, binding to CD74 in vitro when used at a concentration of 10 µM. 4-CPPC (5, 10, and 25 µM) inhibits MIF-2-induced ERK1/2 phosphorylation in primary human skin fibroblasts.
Brand:CaymanSKU:30068 - 10 mgAvailable on backorder
4-CPPC is an inhibitor of macrophage migration inhibitory factor-2 (MIF-2; IC50 = 27 µM).{46807} It is selective for MIF-2 over MIF-1 (IC50 = 450 µM). It inhibits MIF-2, but not MIF-1, binding to CD74 in vitro when used at a concentration of 10 µM. 4-CPPC (5, 10, and 25 µM) inhibits MIF-2-induced ERK1/2 phosphorylation in primary human skin fibroblasts.
Brand:CaymanSKU:30068 - 5 mgAvailable on backorder
4-CPPC is an inhibitor of macrophage migration inhibitory factor-2 (MIF-2; IC50 = 27 µM).{46807} It is selective for MIF-2 over MIF-1 (IC50 = 450 µM). It inhibits MIF-2, but not MIF-1, binding to CD74 in vitro when used at a concentration of 10 µM. 4-CPPC (5, 10, and 25 µM) inhibits MIF-2-induced ERK1/2 phosphorylation in primary human skin fibroblasts.
Brand:CaymanSKU:30068 - 500 µgAvailable on backorder
4-cyano MDMB-BUTINACA (Item No. 26507) is an analytical reference standard categorized as a synthetic cannabinoid.{22072} This product is intended for research and forensic applications.
Brand:CaymanSKU:26507 - 1 mgAvailable on backorder
4-cyano MDMB-BUTINACA (Item No. 26507) is an analytical reference standard categorized as a synthetic cannabinoid.{22072} This product is intended for research and forensic applications.
Brand:CaymanSKU:26507 - 5 mgAvailable on backorder
Brand:CaymanSKU:10007084 - 1 gAvailable on backorder
Brand:CaymanSKU:10007084 - 10 gAvailable on backorder
Brand:CaymanSKU:10007084 - 5 gAvailable on backorder
Brand:CaymanSKU:10007084 - 500 mgAvailable on backorder
4-DAMP is a potent antagonist of the muscarinic M3 receptor (pKi = 9.3).{23026,23027,23044} It is routinely used to study the regulation and functions of the M3 receptor.{23024,23023} 4-DAMP also has a high affinity for the closely-related M5 receptor (pKi = 8.9).{23044}
Brand:CaymanSKU:-4-DAMP is a potent antagonist of the muscarinic M3 receptor (pKi = 9.3).{23026,23027,23044} It is routinely used to study the regulation and functions of the M3 receptor.{23024,23023} 4-DAMP also has a high affinity for the closely-related M5 receptor (pKi = 8.9).{23044}
Brand:CaymanSKU:-4-DAMP is a potent antagonist of the muscarinic M3 receptor (pKi = 9.3).{23026,23027,23044} It is routinely used to study the regulation and functions of the M3 receptor.{23024,23023} 4-DAMP also has a high affinity for the closely-related M5 receptor (pKi = 8.9).{23044}
Brand:CaymanSKU:-4-deoxy Nivalenol is a natural type B trichothecene produced by certain species of the fungus Fusarium, particularly those found on cereal crops, including wheat, barley, oats, maize, and rye.{24416,24414} This mycotoxin can induce vomiting, diarrhea, and weight loss as well as other physiological and toxicological effects.{24415} It inhibits protein biosynthesis, binds to peptidyl transferase, and inhibits the synthesis of RNA and DNA, contributing to immunotoxicity.{24417} It passes the blood-brain barrier at different rates in different animals and this may be related to anorexia.{24415}
Brand:CaymanSKU:11428 - 1 mgAvailable on backorder
4-deoxy Nivalenol is a natural type B trichothecene produced by certain species of the fungus Fusarium, particularly those found on cereal crops, including wheat, barley, oats, maize, and rye.{24416,24414} This mycotoxin can induce vomiting, diarrhea, and weight loss as well as other physiological and toxicological effects.{24415} It inhibits protein biosynthesis, binds to peptidyl transferase, and inhibits the synthesis of RNA and DNA, contributing to immunotoxicity.{24417} It passes the blood-brain barrier at different rates in different animals and this may be related to anorexia.{24415}
Brand:CaymanSKU:11428 - 5 mgAvailable on backorder
4-deoxy Nivalenol is a natural type B trichothecene produced by certain species of the fungus Fusarium, particularly those found on cereal crops, including wheat, barley, oats, maize, and rye.{24416,24414} This mycotoxin can induce vomiting, diarrhea, and weight loss as well as other physiological and toxicological effects.{24415} It inhibits protein biosynthesis, binds to peptidyl transferase, and inhibits the synthesis of RNA and DNA, contributing to immunotoxicity.{24417} It passes the blood-brain barrier at different rates in different animals and this may be related to anorexia.{24415}
Brand:CaymanSKU:11428 - 500 µgAvailable on backorder
4-deoxy Nivalenol-13C15 is intended for use as an internal standard for the quantification of 4-deoxy nivalenol (Item No. 11428) by GC- or LC-MS. 4-deoxy Nivalenol is a trichothecene mycotoxin that has been found in Fusarium.{24416} It binds to eukaryotic ribosomes and inhibits protein synthesis in mice when administered at doses ranging from 5 to 25 mg/kg. 4-deoxy Nivalenol (0.1 and 0.2 mg/kg) induces emesis in pigs and decreases feed consumption in pigs when administered at a dose of 40 ppb in the diet.{58158} It induces lethality in mice (LD50 = 46-78 mg/kg).{58159} 4-deoxy Nivalenol has been found in F. graminearum-infected cereal grains such as wheat, barley, and corn.
Brand:CaymanSKU:31249 - 1.2 mlAvailable on backorder
4-deoxy Pyridoxine (DOP) is a vitamin B6 antimetabolite with diverse biological activities.{38612,38613,38614,38615,38616} It inhibits transport of pyridoxine (Item No. 20706), pyridoxal, and pyridoxamine in and reduces growth of S. carlsbergensis cells.{38612} DOP inhibits sphingosine-1-phosphate (S1P) lyase and reduces cyclic stretch-induced apoptosis in alveolar epithelial MLE-12 cells.{38613} DOP (5 mg, i.p.) reduces lysyl oxidase activity by 26% and reduces collagen and elastin crosslinking, resulting in limb abnormalities in chick embryos.{38614} It decreases latency to first seizure in mice (ED50 = 1 mmol/kg) and increases the occurrence and duration of myoclonic responses in baboons with photosensitive epilepsy.{38615} DOP reduces TNF-α and IL-6 production in mice infected with T. spiralis.{38616}
Brand:CaymanSKU:21863 -Out of stock
4-deoxy Pyridoxine (DOP) is a vitamin B6 antimetabolite with diverse biological activities.{38612,38613,38614,38615,38616} It inhibits transport of pyridoxine (Item No. 20706), pyridoxal, and pyridoxamine in and reduces growth of S. carlsbergensis cells.{38612} DOP inhibits sphingosine-1-phosphate (S1P) lyase and reduces cyclic stretch-induced apoptosis in alveolar epithelial MLE-12 cells.{38613} DOP (5 mg, i.p.) reduces lysyl oxidase activity by 26% and reduces collagen and elastin crosslinking, resulting in limb abnormalities in chick embryos.{38614} It decreases latency to first seizure in mice (ED50 = 1 mmol/kg) and increases the occurrence and duration of myoclonic responses in baboons with photosensitive epilepsy.{38615} DOP reduces TNF-α and IL-6 production in mice infected with T. spiralis.{38616}
Brand:CaymanSKU:21863 -Out of stock
4-deoxy Pyridoxine (DOP) is a vitamin B6 antimetabolite with diverse biological activities.{38612,38613,38614,38615,38616} It inhibits transport of pyridoxine (Item No. 20706), pyridoxal, and pyridoxamine in and reduces growth of S. carlsbergensis cells.{38612} DOP inhibits sphingosine-1-phosphate (S1P) lyase and reduces cyclic stretch-induced apoptosis in alveolar epithelial MLE-12 cells.{38613} DOP (5 mg, i.p.) reduces lysyl oxidase activity by 26% and reduces collagen and elastin crosslinking, resulting in limb abnormalities in chick embryos.{38614} It decreases latency to first seizure in mice (ED50 = 1 mmol/kg) and increases the occurrence and duration of myoclonic responses in baboons with photosensitive epilepsy.{38615} DOP reduces TNF-α and IL-6 production in mice infected with T. spiralis.{38616}
Brand:CaymanSKU:21863 -Out of stock
4-deoxy Pyridoxine (DOP) is a vitamin B6 antimetabolite with diverse biological activities.{38612,38613,38614,38615,38616} It inhibits transport of pyridoxine (Item No. 20706), pyridoxal, and pyridoxamine in and reduces growth of S. carlsbergensis cells.{38612} DOP inhibits sphingosine-1-phosphate (S1P) lyase and reduces cyclic stretch-induced apoptosis in alveolar epithelial MLE-12 cells.{38613} DOP (5 mg, i.p.) reduces lysyl oxidase activity by 26% and reduces collagen and elastin crosslinking, resulting in limb abnormalities in chick embryos.{38614} It decreases latency to first seizure in mice (ED50 = 1 mmol/kg) and increases the occurrence and duration of myoclonic responses in baboons with photosensitive epilepsy.{38615} DOP reduces TNF-α and IL-6 production in mice infected with T. spiralis.{38616}
Brand:CaymanSKU:21863 -Out of stock
4-deoxy-4α-Phorbol is a tetracyclic diterpene found in croton oil.{39635,39636} It has been used in the semisynthesis of inhibitors of the HIV-1-induced cytopathic effect on MT-4 cells and 4α-phorbol esters.
Brand:CaymanSKU:24998 - 1 mgAvailable on backorder
4-deoxy-4α-Phorbol is a tetracyclic diterpene found in croton oil.{39635,39636} It has been used in the semisynthesis of inhibitors of the HIV-1-induced cytopathic effect on MT-4 cells and 4α-phorbol esters.
Brand:CaymanSKU:24998 - 10 mgAvailable on backorder
4-deoxy-4α-Phorbol is a tetracyclic diterpene found in croton oil.{39635,39636} It has been used in the semisynthesis of inhibitors of the HIV-1-induced cytopathic effect on MT-4 cells and 4α-phorbol esters.
Brand:CaymanSKU:24998 - 25 mgAvailable on backorder
4-deoxy-4α-Phorbol is a tetracyclic diterpene found in croton oil.{39635,39636} It has been used in the semisynthesis of inhibitors of the HIV-1-induced cytopathic effect on MT-4 cells and 4α-phorbol esters.
Brand:CaymanSKU:24998 - 5 mgAvailable on backorder
4-Deoxypyridoxine phosphate is a vitamin B6 analog and an inhibitor of sphingosine-1-phosphate (S1P) lyase.{50834} It induces accumulation of [3H]sphinganine-1-phosphate ([3H]dhS1P), an S1P lyase substrate, in IT-79MTNC3 cells that endogenously express high levels of S1P lyase (EC50s = 100 µM in the absence and presence of vitamin B6, respectively).
Brand:CaymanSKU:29973 - 1 mgAvailable on backorder
4-Deoxypyridoxine phosphate is a vitamin B6 analog and an inhibitor of sphingosine-1-phosphate (S1P) lyase.{50834} It induces accumulation of [3H]sphinganine-1-phosphate ([3H]dhS1P), an S1P lyase substrate, in IT-79MTNC3 cells that endogenously express high levels of S1P lyase (EC50s = 100 µM in the absence and presence of vitamin B6, respectively).
Brand:CaymanSKU:29973 - 10 mgAvailable on backorder
4-Deoxypyridoxine phosphate is a vitamin B6 analog and an inhibitor of sphingosine-1-phosphate (S1P) lyase.{50834} It induces accumulation of [3H]sphinganine-1-phosphate ([3H]dhS1P), an S1P lyase substrate, in IT-79MTNC3 cells that endogenously express high levels of S1P lyase (EC50s = 100 µM in the absence and presence of vitamin B6, respectively).
Brand:CaymanSKU:29973 - 25 mgAvailable on backorder
4-Deoxypyridoxine phosphate is a vitamin B6 analog and an inhibitor of sphingosine-1-phosphate (S1P) lyase.{50834} It induces accumulation of [3H]sphinganine-1-phosphate ([3H]dhS1P), an S1P lyase substrate, in IT-79MTNC3 cells that endogenously express high levels of S1P lyase (EC50s = 100 µM in the absence and presence of vitamin B6, respectively).
Brand:CaymanSKU:29973 - 5 mgAvailable on backorder
4-desmethoxy Omeprazole is a potential impurity found in commercial omeprazole and esomeprazole magnesium preparations. Omeprazole (Item No. 14880) is a selective and irreversible inhibitor of the gastric H+/K+ ATPase pump (IC50 = 1.1 μM).{14045} It is a racemic mixture of two enantiomers, (S)-omeprazole (esomeprazole magnesium; Item No. 17326) and (R)-omeprazole (Item No. 18874), which are prodrugs of the active sulfonamide which is formed by acid-stimulated conversion.{18256,18249} Both enantiomers are extensively metabolized by the cytochrome P450 (CYP) isomers CYP2C19 and CYP3A4.{18249}
Brand:CaymanSKU:22122 -Out of stock
4-desmethoxy Omeprazole is a potential impurity found in commercial omeprazole and esomeprazole magnesium preparations. Omeprazole (Item No. 14880) is a selective and irreversible inhibitor of the gastric H+/K+ ATPase pump (IC50 = 1.1 μM).{14045} It is a racemic mixture of two enantiomers, (S)-omeprazole (esomeprazole magnesium; Item No. 17326) and (R)-omeprazole (Item No. 18874), which are prodrugs of the active sulfonamide which is formed by acid-stimulated conversion.{18256,18249} Both enantiomers are extensively metabolized by the cytochrome P450 (CYP) isomers CYP2C19 and CYP3A4.{18249}
Brand:CaymanSKU:22122 -Out of stock
4-desmethoxy Omeprazole is a potential impurity found in commercial omeprazole and esomeprazole magnesium preparations. Omeprazole (Item No. 14880) is a selective and irreversible inhibitor of the gastric H+/K+ ATPase pump (IC50 = 1.1 μM).{14045} It is a racemic mixture of two enantiomers, (S)-omeprazole (esomeprazole magnesium; Item No. 17326) and (R)-omeprazole (Item No. 18874), which are prodrugs of the active sulfonamide which is formed by acid-stimulated conversion.{18256,18249} Both enantiomers are extensively metabolized by the cytochrome P450 (CYP) isomers CYP2C19 and CYP3A4.{18249}
Brand:CaymanSKU:22122 -Out of stock
4-desmethoxy Omeprazole is a potential impurity found in commercial omeprazole and esomeprazole magnesium preparations. Omeprazole (Item No. 14880) is a selective and irreversible inhibitor of the gastric H+/K+ ATPase pump (IC50 = 1.1 μM).{14045} It is a racemic mixture of two enantiomers, (S)-omeprazole (esomeprazole magnesium; Item No. 17326) and (R)-omeprazole (Item No. 18874), which are prodrugs of the active sulfonamide which is formed by acid-stimulated conversion.{18256,18249} Both enantiomers are extensively metabolized by the cytochrome P450 (CYP) isomers CYP2C19 and CYP3A4.{18249}
Brand:CaymanSKU:22122 -Out of stock
4-epi Minocycline is the main degradation product of and a potential impurity in commercial preparations of minocycline.{37048,37047} Minocycline (Item No. 14454) is a broad spectrum tetracycline antibiotic that has a particularly long half-life in serum. Formulations containing minocycline have been used in the treatment of acne in older patients.{22890} Minocycline also has both anti-inflammatory and neuroprotective actions.{22888,22889}
Brand:CaymanSKU:90001066 - 500 µgAvailable on backorder
Chlortetracycline is an analog of tetracycline (Item No. 14328), a broad spectrum antibiotic. In addition to its actions against microorganisms, chlortetracycline suppresses inflammation by inhibiting neutrophil action and other aspects of the innate immune response.{27378,27379,27377,17512} 4-epi-Chlortetracycline is an epimer of chlortetracycline.
Brand:CaymanSKU:-Out of stock
Chlortetracycline is an analog of tetracycline (Item No. 14328), a broad spectrum antibiotic. In addition to its actions against microorganisms, chlortetracycline suppresses inflammation by inhibiting neutrophil action and other aspects of the innate immune response.{27378,27379,27377,17512} 4-epi-Chlortetracycline is an epimer of chlortetracycline.
Brand:CaymanSKU:-Out of stock
Chlortetracycline is an analog of tetracycline (Item No. 14328), a broad spectrum antibiotic. In addition to its actions against microorganisms, chlortetracycline suppresses inflammation by inhibiting neutrophil action and other aspects of the innate immune response.{27378,27379,27377,17512} 4-epi-Chlortetracycline is an epimer of chlortetracycline.
Brand:CaymanSKU:-Out of stock
4-Epianhydrochlortetracycline is a derivative of tetracycline (Item No. 14328).{41116} It inhibits matrix metalloproteinase-9 (MMP-9) activity in a dose-dependent manner in an assay for collagen degradation. 4-Epianhydrochlortetracycline also completely inhibits neutrophil-derived MMP-9 degradation of denatured collagen at a concentration of 500 μg/ml. Unlike tetracycline, 4-epianhydrochlortetracycline lacks antibiotic activity.
Brand:CaymanSKU:23146 - 1 mgAvailable on backorder
4-Epianhydrochlortetracycline is a derivative of tetracycline (Item No. 14328).{41116} It inhibits matrix metalloproteinase-9 (MMP-9) activity in a dose-dependent manner in an assay for collagen degradation. 4-Epianhydrochlortetracycline also completely inhibits neutrophil-derived MMP-9 degradation of denatured collagen at a concentration of 500 μg/ml. Unlike tetracycline, 4-epianhydrochlortetracycline lacks antibiotic activity.
Brand:CaymanSKU:23146 - 5 mgAvailable on backorder
4-Epidoxycycline is the 4-epimer hepatic metabolite of the antibiotic doxycycline (Item No. 14422).{41111,41110} Unlike doxycycline, 4-epidoxycycline lacks antibiotic activity, therefore, it may not induce the intestinal inflammation in mice associated with doxycycline use. It is an alternative to doxycycline to inactivate the transactivator protein tTA or activate the reverse transactivator rtTA protein in Tet-Off- and Tet-On-based gene expression systems in vitro and in mice.
Brand:CaymanSKU:23225 - 1 mgAvailable on backorder
4-Epidoxycycline is the 4-epimer hepatic metabolite of the antibiotic doxycycline (Item No. 14422).{41111,41110} Unlike doxycycline, 4-epidoxycycline lacks antibiotic activity, therefore, it may not induce the intestinal inflammation in mice associated with doxycycline use. It is an alternative to doxycycline to inactivate the transactivator protein tTA or activate the reverse transactivator rtTA protein in Tet-Off- and Tet-On-based gene expression systems in vitro and in mice.
Brand:CaymanSKU:23225 - 500 µgAvailable on backorder
Substituted cathinones, including 4-methylmethcathinone (hydrochloride) (Item No. 10801) and 4-methylethcathinone (hydrochloride) (Item No. 9001069) are psychoactive compounds commonly used as recreational drugs.{19500,19508} 4-Ethylethcathinone is a substituted cathinone with potential for abuse. Its physiological and toxicological properties have not been characterized. This product is intended for forensic applications.
Brand:CaymanSKU:11197 - 10 mgAvailable on backorder
Substituted cathinones, including 4-methylmethcathinone (hydrochloride) (Item No. 10801) and 4-methylethcathinone (hydrochloride) (Item No. 9001069) are psychoactive compounds commonly used as recreational drugs.{19500,19508} 4-Ethylethcathinone is a substituted cathinone with potential for abuse. Its physiological and toxicological properties have not been characterized. This product is intended for forensic applications.
Brand:CaymanSKU:11197 - 5 mgAvailable on backorder
Substituted cathinones, including 4-methylmethcathinone (hydrochloride) (Item No. 10801) and 4-methylethcathinone (hydrochloride) (Item No. 9001069) are psychoactive compounds commonly used as recreational drugs.{19500,19508} 4-Ethylethcathinone is a substituted cathinone with potential for abuse. Its physiological and toxicological properties have not been characterized. This product is intended for forensic applications.
Brand:CaymanSKU:11197 - 50 mgAvailable on backorder