Chemicals
Showing 5401–5550 of 41137 results
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3,3′-((2-Chlorophenyl)methylene)bis(4-hydroxy-2H-chromen-2-one) is a non-nucleotide inhibitor of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1; Ki = 50 µM).{48700,50816} It also inhibits urease (IC50 = 84.53 µM for the Jack bean enzyme).{48701}
Brand:CaymanSKU:29864 - 10 mgAvailable on backorder
3,3′-((2-Chlorophenyl)methylene)bis(4-hydroxy-2H-chromen-2-one) is a non-nucleotide inhibitor of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1; Ki = 50 µM).{48700,50816} It also inhibits urease (IC50 = 84.53 µM for the Jack bean enzyme).{48701}
Brand:CaymanSKU:29864 - 25 mgAvailable on backorder
3,3′-((2-Chlorophenyl)methylene)bis(4-hydroxy-2H-chromen-2-one) is a non-nucleotide inhibitor of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1; Ki = 50 µM).{48700,50816} It also inhibits urease (IC50 = 84.53 µM for the Jack bean enzyme).{48701}
Brand:CaymanSKU:29864 - 5 mgAvailable on backorder
3,3′-Dihexyloxacarbocyanine (DiOC6(3)) is a lipophilic fluorescent dye with excitation/emission spectra of 484/501 nm, respectively.{39274} At high concentrations, DiOC6(3) accumulates in the endoplasmic reticulum (ER) and has been used to visualize ER in moss, yeast, and muscle cells. At low concentrations, DiOC6(3) accumulates in mitochondria and has been used to assess mitochondrial dislocations, fusion, and fission in living cells, as well as to visualize cellular apoptosis. DiOC6(3) can also be used to assess cell membrane potential, as depolarization directly correlates with increased fluorescence.{39275,39276} DiOC6(3) photoexcitation inactivates intracellular organelle movement and inhibits microtubule polymerization in vitro.{39277}
Brand:CaymanSKU:23124 - 1 gAvailable on backorder
3,3′-Dihexyloxacarbocyanine (DiOC6(3)) is a lipophilic fluorescent dye with excitation/emission spectra of 484/501 nm, respectively.{39274} At high concentrations, DiOC6(3) accumulates in the endoplasmic reticulum (ER) and has been used to visualize ER in moss, yeast, and muscle cells. At low concentrations, DiOC6(3) accumulates in mitochondria and has been used to assess mitochondrial dislocations, fusion, and fission in living cells, as well as to visualize cellular apoptosis. DiOC6(3) can also be used to assess cell membrane potential, as depolarization directly correlates with increased fluorescence.{39275,39276} DiOC6(3) photoexcitation inactivates intracellular organelle movement and inhibits microtubule polymerization in vitro.{39277}
Brand:CaymanSKU:23124 - 500 mgAvailable on backorder
3,3′-Diiodo-L-thyronine is a metabolite of thyroid hormone that is also known as T2 or 3,3’-T2.{27332} It is derived enzymatically from triiodothyronine isoforms T3 and reverse T3. T2 and its analog 3,5-T2 stimulate the activity of cytochrome c oxidase by blocking inhibition by ATP.{27333,27334}
Brand:CaymanSKU:-Out of stock
3,3′-Diiodo-L-thyronine is a metabolite of thyroid hormone that is also known as T2 or 3,3’-T2.{27332} It is derived enzymatically from triiodothyronine isoforms T3 and reverse T3. T2 and its analog 3,5-T2 stimulate the activity of cytochrome c oxidase by blocking inhibition by ATP.{27333,27334}
Brand:CaymanSKU:-Out of stock
3,3′-Diiodo-L-thyronine is a metabolite of thyroid hormone that is also known as T2 or 3,3’-T2.{27332} It is derived enzymatically from triiodothyronine isoforms T3 and reverse T3. T2 and its analog 3,5-T2 stimulate the activity of cytochrome c oxidase by blocking inhibition by ATP.{27333,27334}
Brand:CaymanSKU:-Out of stock
3,3′-Diiodo-L-thyronine is a metabolite of thyroid hormone that is also known as T2 or 3,3’-T2.{27332} It is derived enzymatically from triiodothyronine isoforms T3 and reverse T3. T2 and its analog 3,5-T2 stimulate the activity of cytochrome c oxidase by blocking inhibition by ATP.{27333,27334}
Brand:CaymanSKU:-Out of stock
3,3′,5-Triiodo-L-thyronine (T3) is a thyroid hormone.{61095} It is produced by 5′-monodeiodination of the prohormone thyroxine (T4) in various tissues, including liver and kidney. T3 is an agonist of thyroid hormone receptors TRα and TRβ (Kis = 2.3 nM for both) that modulates diverse biological properties, including metabolism, cardiac function, growth, and redox signaling.{27008,27007,27010,27009} It also functions as an inhibitor of L-type amino acid transporter 1 (LAT1), inhibiting LAT1-mediated leucine uptake in HEK293 cells when used at a concentration of 10 µM.{59277}
Brand:CaymanSKU:- 3,3′,5-Triiodo-L-thyronine (T3) is a thyroid hormone.{61095} It is produced by 5′-monodeiodination of the prohormone thyroxine (T4) in various tissues, including liver and kidney. T3 is an agonist of thyroid hormone receptors TRα and TRβ (Kis = 2.3 nM for both) that modulates diverse biological properties, including metabolism, cardiac function, growth, and redox signaling.{27008,27007,27010,27009} It also functions as an inhibitor of L-type amino acid transporter 1 (LAT1), inhibiting LAT1-mediated leucine uptake in HEK293 cells when used at a concentration of 10 µM.{59277}
Brand:CaymanSKU:- 3,3′,5-Triiodo-L-thyronine (T3) is a thyroid hormone.{61095} It is produced by 5′-monodeiodination of the prohormone thyroxine (T4) in various tissues, including liver and kidney. T3 is an agonist of thyroid hormone receptors TRα and TRβ (Kis = 2.3 nM for both) that modulates diverse biological properties, including metabolism, cardiac function, growth, and redox signaling.{27008,27007,27010,27009} It also functions as an inhibitor of L-type amino acid transporter 1 (LAT1), inhibiting LAT1-mediated leucine uptake in HEK293 cells when used at a concentration of 10 µM.{59277}
Brand:CaymanSKU:- 3,3′,5-Triiodo-L-thyronine (T3) is a thyroid hormone.{61095} It is produced by 5′-monodeiodination of the prohormone thyroxine (T4) in various tissues, including liver and kidney. T3 is an agonist of thyroid hormone receptors TRα and TRβ (Kis = 2.3 nM for both) that modulates diverse biological properties, including metabolism, cardiac function, growth, and redox signaling.{27008,27007,27010,27009} It also functions as an inhibitor of L-type amino acid transporter 1 (LAT1), inhibiting LAT1-mediated leucine uptake in HEK293 cells when used at a concentration of 10 µM.{59277}
Brand:CaymanSKU:-
3,3′,5’-Triiodo-L-thyronine, also known as reverse T3 (rT3), is a thyroid hormone generated by deiodination of the prohormone thyroxine. It is about 1,000-fold less active at the thyroid hormone receptors TRα and TRβ than 3,3′,5-triiodo-L-thyronine (Item No. 16028) and commonly described as inactive.{28789,28791} However, high serum levels of rT3 are found in neonates and in certain conditions.{28795,28793,28790,28792} It reportedly activates TRΔα1, a native form of TRα that lacks a nuclear localization signal and functions in the cytoplasm.{28794} Through this action, rT3 initiates actin polymerization, particularly in astrocytes and neurons.{28794}
Brand:CaymanSKU:-Available on backorder
3,3′,5’-Triiodo-L-thyronine, also known as reverse T3 (rT3), is a thyroid hormone generated by deiodination of the prohormone thyroxine. It is about 1,000-fold less active at the thyroid hormone receptors TRα and TRβ than 3,3′,5-triiodo-L-thyronine (Item No. 16028) and commonly described as inactive.{28789,28791} However, high serum levels of rT3 are found in neonates and in certain conditions.{28795,28793,28790,28792} It reportedly activates TRΔα1, a native form of TRα that lacks a nuclear localization signal and functions in the cytoplasm.{28794} Through this action, rT3 initiates actin polymerization, particularly in astrocytes and neurons.{28794}
Brand:CaymanSKU:-Available on backorder
3,3′,5’-Triiodo-L-thyronine, also known as reverse T3 (rT3), is a thyroid hormone generated by deiodination of the prohormone thyroxine. It is about 1,000-fold less active at the thyroid hormone receptors TRα and TRβ than 3,3′,5-triiodo-L-thyronine (Item No. 16028) and commonly described as inactive.{28789,28791} However, high serum levels of rT3 are found in neonates and in certain conditions.{28795,28793,28790,28792} It reportedly activates TRΔα1, a native form of TRα that lacks a nuclear localization signal and functions in the cytoplasm.{28794} Through this action, rT3 initiates actin polymerization, particularly in astrocytes and neurons.{28794}
Brand:CaymanSKU:-Available on backorder
3,3′,5’-Triiodo-L-thyronine, also known as reverse T3 (rT3), is a thyroid hormone generated by deiodination of the prohormone thyroxine. It is about 1,000-fold less active at the thyroid hormone receptors TRα and TRβ than 3,3′,5-triiodo-L-thyronine (Item No. 16028) and commonly described as inactive.{28789,28791} However, high serum levels of rT3 are found in neonates and in certain conditions.{28795,28793,28790,28792} It reportedly activates TRΔα1, a native form of TRα that lacks a nuclear localization signal and functions in the cytoplasm.{28794} Through this action, rT3 initiates actin polymerization, particularly in astrocytes and neurons.{28794}
Brand:CaymanSKU:-Available on backorder
3,3′-Dioctadecyloxacarbocyanine is a lipophilic fluorescent dye. It exhibits polarity-dependent fluorescence that is enhanced when incorporated into membranes or lipophilic molecules. Upon membrane incorporation, 3,3′-dioctadecyloxacarbocyanine rapidly diffuses to stain the entire cell membrane.{43912} It has been used in the clonal analysis of S. purparatus embryos. 3,3′-Dioctadecyloxacarbocyanine displays excitation/emission maxima of 484/501 nm, respectively, and can be used for live cell applications.
Brand:CaymanSKU:27876 - 10 mgAvailable on backorder
3,3′-Dioctadecyloxacarbocyanine is a lipophilic fluorescent dye. It exhibits polarity-dependent fluorescence that is enhanced when incorporated into membranes or lipophilic molecules. Upon membrane incorporation, 3,3′-dioctadecyloxacarbocyanine rapidly diffuses to stain the entire cell membrane.{43912} It has been used in the clonal analysis of S. purparatus embryos. 3,3′-Dioctadecyloxacarbocyanine displays excitation/emission maxima of 484/501 nm, respectively, and can be used for live cell applications.
Brand:CaymanSKU:27876 - 25 mgAvailable on backorder
3,3′-Dioctadecyloxacarbocyanine is a lipophilic fluorescent dye. It exhibits polarity-dependent fluorescence that is enhanced when incorporated into membranes or lipophilic molecules. Upon membrane incorporation, 3,3′-dioctadecyloxacarbocyanine rapidly diffuses to stain the entire cell membrane.{43912} It has been used in the clonal analysis of S. purparatus embryos. 3,3′-Dioctadecyloxacarbocyanine displays excitation/emission maxima of 484/501 nm, respectively, and can be used for live cell applications.
Brand:CaymanSKU:27876 - 5 mgAvailable on backorder
3,3′-Dioctadecyloxacarbocyanine is a lipophilic fluorescent dye. It exhibits polarity-dependent fluorescence that is enhanced when incorporated into membranes or lipophilic molecules. Upon membrane incorporation, 3,3′-dioctadecyloxacarbocyanine rapidly diffuses to stain the entire cell membrane.{43912} It has been used in the clonal analysis of S. purparatus embryos. 3,3′-Dioctadecyloxacarbocyanine displays excitation/emission maxima of 484/501 nm, respectively, and can be used for live cell applications.
Brand:CaymanSKU:27876 - 50 mgAvailable on backorder
3,4-Di-O-acetyl-L-fucal is a glycal precursor that has been used in the palladium-catalyzed stereoselective synthesis of glycosides.{56038} It has also been used as a precursor in the copper-catalyzed stereoselective synthesis of 2-deoxyglycosides.{56039}
Brand:CaymanSKU:30864 - 100 mgAvailable on backorder
3,4-Di-O-acetyl-L-fucal is a glycal precursor that has been used in the palladium-catalyzed stereoselective synthesis of glycosides.{56038} It has also been used as a precursor in the copper-catalyzed stereoselective synthesis of 2-deoxyglycosides.{56039}
Brand:CaymanSKU:30864 - 250 mgAvailable on backorder
3,4-Di-O-acetyl-L-fucal is a glycal precursor that has been used in the palladium-catalyzed stereoselective synthesis of glycosides.{56038} It has also been used as a precursor in the copper-catalyzed stereoselective synthesis of 2-deoxyglycosides.{56039}
Brand:CaymanSKU:30864 - 50 mgAvailable on backorder
3,4-Dicaffeoylquinic acid (3,4-DCQA) is a polyphenol with diverse biological activities.{41896,41897,41898,41899} 3,4-DCQA (1-500 μg/ml) inhibits acetylcholinesterase (ACE) and α-glucosidase in a concentration-dependent manner.{41896,41898} It reduces mutagenicity of Trp-P-1 against S. typhimurium by 59% when used at a concentration of 0.57 mM.{41897} 3,4-DCQA has antioxidant activity in ferric reducing, β-carotene bleaching, and DPPH scavenging assays (EC50s = 2.18, 23.85, and 68.91 μg/ml, respectively).{41898} It is cytotoxic to NCI-H23 lung adenocarcinoma cells (EC50 = 3.26 μg/ml). In vivo, 3,4-DCQA (50 mg/kg) increases tumor necrosis factor-related apoptosis inducing ligand (TRAIL) mRNA, reduces influenza H1N1 hemagglutinin (HA) mRNA, and increases survival in a mouse model of influenza A infection.{41899}
Brand:CaymanSKU:25053 - 10 mgAvailable on backorder
3,4-Dicaffeoylquinic acid (3,4-DCQA) is a polyphenol with diverse biological activities.{41896,41897,41898,41899} 3,4-DCQA (1-500 μg/ml) inhibits acetylcholinesterase (ACE) and α-glucosidase in a concentration-dependent manner.{41896,41898} It reduces mutagenicity of Trp-P-1 against S. typhimurium by 59% when used at a concentration of 0.57 mM.{41897} 3,4-DCQA has antioxidant activity in ferric reducing, β-carotene bleaching, and DPPH scavenging assays (EC50s = 2.18, 23.85, and 68.91 μg/ml, respectively).{41898} It is cytotoxic to NCI-H23 lung adenocarcinoma cells (EC50 = 3.26 μg/ml). In vivo, 3,4-DCQA (50 mg/kg) increases tumor necrosis factor-related apoptosis inducing ligand (TRAIL) mRNA, reduces influenza H1N1 hemagglutinin (HA) mRNA, and increases survival in a mouse model of influenza A infection.{41899}
Brand:CaymanSKU:25053 - 25 mgAvailable on backorder
3,4-Dicaffeoylquinic acid (3,4-DCQA) is a polyphenol with diverse biological activities.{41896,41897,41898,41899} 3,4-DCQA (1-500 μg/ml) inhibits acetylcholinesterase (ACE) and α-glucosidase in a concentration-dependent manner.{41896,41898} It reduces mutagenicity of Trp-P-1 against S. typhimurium by 59% when used at a concentration of 0.57 mM.{41897} 3,4-DCQA has antioxidant activity in ferric reducing, β-carotene bleaching, and DPPH scavenging assays (EC50s = 2.18, 23.85, and 68.91 μg/ml, respectively).{41898} It is cytotoxic to NCI-H23 lung adenocarcinoma cells (EC50 = 3.26 μg/ml). In vivo, 3,4-DCQA (50 mg/kg) increases tumor necrosis factor-related apoptosis inducing ligand (TRAIL) mRNA, reduces influenza H1N1 hemagglutinin (HA) mRNA, and increases survival in a mouse model of influenza A infection.{41899}
Brand:CaymanSKU:25053 - 5 mgAvailable on backorder
3,4-Dicaffeoylquinic acid (3,4-DCQA) is a polyphenol with diverse biological activities.{41896,41897,41898,41899} 3,4-DCQA (1-500 μg/ml) inhibits acetylcholinesterase (ACE) and α-glucosidase in a concentration-dependent manner.{41896,41898} It reduces mutagenicity of Trp-P-1 against S. typhimurium by 59% when used at a concentration of 0.57 mM.{41897} 3,4-DCQA has antioxidant activity in ferric reducing, β-carotene bleaching, and DPPH scavenging assays (EC50s = 2.18, 23.85, and 68.91 μg/ml, respectively).{41898} It is cytotoxic to NCI-H23 lung adenocarcinoma cells (EC50 = 3.26 μg/ml). In vivo, 3,4-DCQA (50 mg/kg) increases tumor necrosis factor-related apoptosis inducing ligand (TRAIL) mRNA, reduces influenza H1N1 hemagglutinin (HA) mRNA, and increases survival in a mouse model of influenza A infection.{41899}
Brand:CaymanSKU:25053 - 50 mgAvailable on backorder
3,4-Dichloroisocoumarin (3,4-DCI) is a serine protease inhibitor.{38255} It completely inhibits enzyme activity of 24 serine proteases including human leukocyte elastase, thrombin, plasmin, Factor Xa, and Factor XIIa in vitro. 3,4-DCI stimulates caseinolytic activity of bovine pituitary multicatalytic proteinase complex (MPC) by inducing a conformational change in the MPC that exposes the caseinolytic active site.{38256} It has been used to functionally characterize the catalytic activities of multiple proteases including rat liver MPC and extracellular lipase.{38257,38258}
Brand:CaymanSKU:21194 -Out of stock
3,4-Dichloroisocoumarin (3,4-DCI) is a serine protease inhibitor.{38255} It completely inhibits enzyme activity of 24 serine proteases including human leukocyte elastase, thrombin, plasmin, Factor Xa, and Factor XIIa in vitro. 3,4-DCI stimulates caseinolytic activity of bovine pituitary multicatalytic proteinase complex (MPC) by inducing a conformational change in the MPC that exposes the caseinolytic active site.{38256} It has been used to functionally characterize the catalytic activities of multiple proteases including rat liver MPC and extracellular lipase.{38257,38258}
Brand:CaymanSKU:21194 -Out of stock
3,4-Dichloroisocoumarin (3,4-DCI) is a serine protease inhibitor.{38255} It completely inhibits enzyme activity of 24 serine proteases including human leukocyte elastase, thrombin, plasmin, Factor Xa, and Factor XIIa in vitro. 3,4-DCI stimulates caseinolytic activity of bovine pituitary multicatalytic proteinase complex (MPC) by inducing a conformational change in the MPC that exposes the caseinolytic active site.{38256} It has been used to functionally characterize the catalytic activities of multiple proteases including rat liver MPC and extracellular lipase.{38257,38258}
Brand:CaymanSKU:21194 -Out of stock
3,4-Dichloromethcathinone (hydrochloride) (Item No. 25376) is an analytical reference standard categorized as a cathinone. This product is intended for research and forensic applications.
Brand:CaymanSKU:25376 - 1 mgAvailable on backorder
3,4-Dichloromethcathinone (hydrochloride) (Item No. 25376) is an analytical reference standard categorized as a cathinone. This product is intended for research and forensic applications.
Brand:CaymanSKU:25376 - 5 mgAvailable on backorder
3,4-difluoro U-50488 (hydrochloride) (Item No. 29566) is an analytical reference standard categorized as a utopioid. This product is intended for research and forensic applications.
Brand:CaymanSKU:29566 - 1 mgAvailable on backorder
3,4-difluoro U-50488 (hydrochloride) (Item No. 29566) is an analytical reference standard categorized as a utopioid. This product is intended for research and forensic applications.
Brand:CaymanSKU:29566 - 5 mgAvailable on backorder
Naratriptan is a selective serotonin 5-HT1B agonist (pKi = 8.9 for human 5-HT1B) used in the treatment of severe cephalic pain, including migraine headaches.{25802,25801,29035} 3,4-dihydro Naratriptan is an impurity formed during the preparation of naratriptan.{29036}
Brand:CaymanSKU:-Available on backorder
Naratriptan is a selective serotonin 5-HT1B agonist (pKi = 8.9 for human 5-HT1B) used in the treatment of severe cephalic pain, including migraine headaches.{25802,25801,29035} 3,4-dihydro Naratriptan is an impurity formed during the preparation of naratriptan.{29036}
Brand:CaymanSKU:-Available on backorder
Naratriptan is a selective serotonin 5-HT1B agonist (pKi = 8.9 for human 5-HT1B) used in the treatment of severe cephalic pain, including migraine headaches.{25802,25801,29035} 3,4-dihydro Naratriptan is an impurity formed during the preparation of naratriptan.{29036}
Brand:CaymanSKU:-Available on backorder
Naratriptan is a selective serotonin 5-HT1B agonist (pKi = 8.9 for human 5-HT1B) used in the treatment of severe cephalic pain, including migraine headaches.{25802,25801,29035} 3,4-dihydro Naratriptan is an impurity formed during the preparation of naratriptan.{29036}
Brand:CaymanSKU:-Available on backorder
3,4-Dihydroquinolin-2(1H)-one is a building block.{52836,52837} It has been used in the synthesis of compounds with antidepressant and anticonvulsant activities, as well as dual ligands of sigma (σ) receptors and the NMDA receptor GluN2b subunit that have antioxidant and neuroprotective properties.
Brand:CaymanSKU:31701 - 1 gAvailable on backorder
3,4-Dihydroquinolin-2(1H)-one is a building block.{52836,52837} It has been used in the synthesis of compounds with antidepressant and anticonvulsant activities, as well as dual ligands of sigma (σ) receptors and the NMDA receptor GluN2b subunit that have antioxidant and neuroprotective properties.
Brand:CaymanSKU:31701 - 10 gAvailable on backorder
3,4-Dihydroquinolin-2(1H)-one is a building block.{52836,52837} It has been used in the synthesis of compounds with antidepressant and anticonvulsant activities, as well as dual ligands of sigma (σ) receptors and the NMDA receptor GluN2b subunit that have antioxidant and neuroprotective properties.
Brand:CaymanSKU:31701 - 25 gAvailable on backorder
3,4-Dihydroquinolin-2(1H)-one is a building block.{52836,52837} It has been used in the synthesis of compounds with antidepressant and anticonvulsant activities, as well as dual ligands of sigma (σ) receptors and the NMDA receptor GluN2b subunit that have antioxidant and neuroprotective properties.
Brand:CaymanSKU:31701 - 5 gAvailable on backorder
3,4-Dihydroxyamphetamine (hydrochloride) (Item No. 30531) is an analytical reference standard categorized as an amphetamine. 3,4-Dihydroxyamphetamine is a metabolite of 3,4-MDMA (Item Nos. ISO60190 | 13971) via the intermediate (±)-MDA (Item Nos. ISO60189 | 11554).{23483,53703} This product is intended for research and forensic applications.
Brand:CaymanSKU:30531 - 1 mgAvailable on backorder
3,4-Dihydroxyamphetamine (hydrochloride) (Item No. 30531) is an analytical reference standard categorized as an amphetamine. 3,4-Dihydroxyamphetamine is a metabolite of 3,4-MDMA (Item Nos. ISO60190 | 13971) via the intermediate (±)-MDA (Item Nos. ISO60189 | 11554).{23483,53703} This product is intended for research and forensic applications.
Brand:CaymanSKU:30531 - 5 mgAvailable on backorder
3,4-Dihydroxybenzaldehyde is a polyphenol that has been found in S. miltiorrhiza and has diverse biological activities, including antibacterial, antioxidative, and anticancer properties.{45267,45268,45269,45270} It is active against methicillin-resistant S. aureus (MRSA) when used at a concentration of 0.01 µg/ml.{45268} It prevents hexavalent chromium-induced formation of reactive oxygen species (ROS) and reactive nitrogen species (RNS) in a concentration-dependent manner and increases glutathione (GSH) levels in isolated human erythrocytes.{45267} 3,4-Dihydroxybenzaldehyde selectively inhibits human DNA topoisomerase II (IC50 = 150 µM) over human topoisomerase I and a variety of mammalian polymerases (IC50s = >200 µM).{45269} It inhibits proliferation of HT-29 cells when used at a concentration of 362 µM but not HCT116 cells at a concentration of 100 µM.{45270,45269}
Brand:CaymanSKU:27547 - 10 gAvailable on backorder
3,4-Dihydroxybenzaldehyde is a polyphenol that has been found in S. miltiorrhiza and has diverse biological activities, including antibacterial, antioxidative, and anticancer properties.{45267,45268,45269,45270} It is active against methicillin-resistant S. aureus (MRSA) when used at a concentration of 0.01 µg/ml.{45268} It prevents hexavalent chromium-induced formation of reactive oxygen species (ROS) and reactive nitrogen species (RNS) in a concentration-dependent manner and increases glutathione (GSH) levels in isolated human erythrocytes.{45267} 3,4-Dihydroxybenzaldehyde selectively inhibits human DNA topoisomerase II (IC50 = 150 µM) over human topoisomerase I and a variety of mammalian polymerases (IC50s = >200 µM).{45269} It inhibits proliferation of HT-29 cells when used at a concentration of 362 µM but not HCT116 cells at a concentration of 100 µM.{45270,45269}
Brand:CaymanSKU:27547 - 100 gAvailable on backorder
3,4-Dihydroxybenzaldehyde is a polyphenol that has been found in S. miltiorrhiza and has diverse biological activities, including antibacterial, antioxidative, and anticancer properties.{45267,45268,45269,45270} It is active against methicillin-resistant S. aureus (MRSA) when used at a concentration of 0.01 µg/ml.{45268} It prevents hexavalent chromium-induced formation of reactive oxygen species (ROS) and reactive nitrogen species (RNS) in a concentration-dependent manner and increases glutathione (GSH) levels in isolated human erythrocytes.{45267} 3,4-Dihydroxybenzaldehyde selectively inhibits human DNA topoisomerase II (IC50 = 150 µM) over human topoisomerase I and a variety of mammalian polymerases (IC50s = >200 µM).{45269} It inhibits proliferation of HT-29 cells when used at a concentration of 362 µM but not HCT116 cells at a concentration of 100 µM.{45270,45269}
Brand:CaymanSKU:27547 - 25 gAvailable on backorder
3,4-Dihydroxybenzaldehyde is a polyphenol that has been found in S. miltiorrhiza and has diverse biological activities, including antibacterial, antioxidative, and anticancer properties.{45267,45268,45269,45270} It is active against methicillin-resistant S. aureus (MRSA) when used at a concentration of 0.01 µg/ml.{45268} It prevents hexavalent chromium-induced formation of reactive oxygen species (ROS) and reactive nitrogen species (RNS) in a concentration-dependent manner and increases glutathione (GSH) levels in isolated human erythrocytes.{45267} 3,4-Dihydroxybenzaldehyde selectively inhibits human DNA topoisomerase II (IC50 = 150 µM) over human topoisomerase I and a variety of mammalian polymerases (IC50s = >200 µM).{45269} It inhibits proliferation of HT-29 cells when used at a concentration of 362 µM but not HCT116 cells at a concentration of 100 µM.{45270,45269}
Brand:CaymanSKU:27547 - 5 gAvailable on backorder
3,4-Dihydroxyphenyl ethanol is a phenolic component of olive oil that inhibits both 12- and 5-LO. The IC50 values for the inhibition of rat platelet 12-LO and rat neutrophil 5-LO are 4.2 and 13 µM, respectively. It does not inhibit, and may actually enhance, COX activity.{4049} 3,4-Dihydroxyphenyl ethanol also protects LDL from both biological and chemical oxidation, suggesting a potential mechanism for the protective effects of olive oil against atherosclerosis.{6597}
Brand:CaymanSKU:70604 - 10 mgAvailable on backorder
3,4-Dihydroxyphenyl ethanol is a phenolic component of olive oil that inhibits both 12- and 5-LO. The IC50 values for the inhibition of rat platelet 12-LO and rat neutrophil 5-LO are 4.2 and 13 µM, respectively. It does not inhibit, and may actually enhance, COX activity.{4049} 3,4-Dihydroxyphenyl ethanol also protects LDL from both biological and chemical oxidation, suggesting a potential mechanism for the protective effects of olive oil against atherosclerosis.{6597}
Brand:CaymanSKU:70604 - 100 mgAvailable on backorder
3,4-Dihydroxyphenyl ethanol is a phenolic component of olive oil that inhibits both 12- and 5-LO. The IC50 values for the inhibition of rat platelet 12-LO and rat neutrophil 5-LO are 4.2 and 13 µM, respectively. It does not inhibit, and may actually enhance, COX activity.{4049} 3,4-Dihydroxyphenyl ethanol also protects LDL from both biological and chemical oxidation, suggesting a potential mechanism for the protective effects of olive oil against atherosclerosis.{6597}
Brand:CaymanSKU:70604 - 5 mgAvailable on backorder
3,4-Dihydroxyphenyl ethanol is a phenolic component of olive oil that inhibits both 12- and 5-LO. The IC50 values for the inhibition of rat platelet 12-LO and rat neutrophil 5-LO are 4.2 and 13 µM, respectively. It does not inhibit, and may actually enhance, COX activity.{4049} 3,4-Dihydroxyphenyl ethanol also protects LDL from both biological and chemical oxidation, suggesting a potential mechanism for the protective effects of olive oil against atherosclerosis.{6597}
Brand:CaymanSKU:70604 - 50 mgAvailable on backorder
3,4-dihydroxyphenylacetic acid (DOPAC) is a metabolite of dopamine (Item No. 21992) formed through deamination by monoamine oxidase (MAO).{36669} DOPAC is further metabolized by catechol-O-methyltransferase (COMT) to form homovanillic acid, and DOPAC levels are increased 5- to 6-fold compared to wild-type in the nucleus accumbens, striatum, and prefrontal cortex of COMT knockout mice. DOPAC oxidation is catalyzed by α-synuclein and oxidized DOPAC binds to monomeric α-synuclein preventing fibrillation.{36668} In vivo, foot shock stress increases DOPAC levels relative to control by approximately 45% in the prefrontal cortex and by 15% in the olfactory tubercles and ventral tegmental area (VTA) in rats.{36667}
Brand:CaymanSKU:24912 - 10 gAvailable on backorder
3,4-dihydroxyphenylacetic acid (DOPAC) is a metabolite of dopamine (Item No. 21992) formed through deamination by monoamine oxidase (MAO).{36669} DOPAC is further metabolized by catechol-O-methyltransferase (COMT) to form homovanillic acid, and DOPAC levels are increased 5- to 6-fold compared to wild-type in the nucleus accumbens, striatum, and prefrontal cortex of COMT knockout mice. DOPAC oxidation is catalyzed by α-synuclein and oxidized DOPAC binds to monomeric α-synuclein preventing fibrillation.{36668} In vivo, foot shock stress increases DOPAC levels relative to control by approximately 45% in the prefrontal cortex and by 15% in the olfactory tubercles and ventral tegmental area (VTA) in rats.{36667}
Brand:CaymanSKU:24912 - 25 gAvailable on backorder
3,4-dihydroxyphenylacetic acid (DOPAC) is a metabolite of dopamine (Item No. 21992) formed through deamination by monoamine oxidase (MAO).{36669} DOPAC is further metabolized by catechol-O-methyltransferase (COMT) to form homovanillic acid, and DOPAC levels are increased 5- to 6-fold compared to wild-type in the nucleus accumbens, striatum, and prefrontal cortex of COMT knockout mice. DOPAC oxidation is catalyzed by α-synuclein and oxidized DOPAC binds to monomeric α-synuclein preventing fibrillation.{36668} In vivo, foot shock stress increases DOPAC levels relative to control by approximately 45% in the prefrontal cortex and by 15% in the olfactory tubercles and ventral tegmental area (VTA) in rats.{36667}
Brand:CaymanSKU:24912 - 5 gAvailable on backorder
3,4-dihydroxyphenylacetic acid (DOPAC) is a metabolite of dopamine (Item No. 21992) formed through deamination by monoamine oxidase (MAO).{36669} DOPAC is further metabolized by catechol-O-methyltransferase (COMT) to form homovanillic acid, and DOPAC levels are increased 5- to 6-fold compared to wild-type in the nucleus accumbens, striatum, and prefrontal cortex of COMT knockout mice. DOPAC oxidation is catalyzed by α-synuclein and oxidized DOPAC binds to monomeric α-synuclein preventing fibrillation.{36668} In vivo, foot shock stress increases DOPAC levels relative to control by approximately 45% in the prefrontal cortex and by 15% in the olfactory tubercles and ventral tegmental area (VTA) in rats.{36667}
Brand:CaymanSKU:24912 - 50 gAvailable on backorder
Methylenedioxy Pyrovalerone (MDPV) (Item No. 10624) is a cathinone commonly found in products sold as bath salts or plant food.{19193,20369} It is regulated as a Schedule 1 compound in the United States.{18947} 3,4-dimethoxy-α-Pyrrolidinopentiophenone is an analog of MDPV, differing only by an opening of the ring structure on the phenyl group. The physiological and toxicological properties of this compound have not been investigated. This product is intended for research and forensic applications.
Brand:CaymanSKU:- Methylenedioxy Pyrovalerone (MDPV) (Item No. 10624) is a cathinone commonly found in products sold as bath salts or plant food.{19193,20369} It is regulated as a Schedule 1 compound in the United States.{18947} 3,4-dimethoxy-α-Pyrrolidinopentiophenone is an analog of MDPV, differing only by an opening of the ring structure on the phenyl group. The physiological and toxicological properties of this compound have not been investigated. This product is intended for research and forensic applications.
Brand:CaymanSKU:- Methylenedioxy Pyrovalerone (MDPV) (Item No. 10624) is a cathinone commonly found in products sold as bath salts or plant food.{19193,20369} It is regulated as a Schedule 1 compound in the United States.{18947} 3,4-dimethoxy-α-Pyrrolidinopentiophenone is an analog of MDPV, differing only by an opening of the ring structure on the phenyl group. The physiological and toxicological properties of this compound have not been investigated. This product is intended for research and forensic applications.
Brand:CaymanSKU:-
3,4-dimethoxy-α-Pyrrolidinopropiophenone (hydrochloride) (Item No. 30034) is an analytical reference standard categorized as a cathinone. This product is intended for research and forensic applications.
Brand:CaymanSKU:30034 - 1 mgAvailable on backorder
3,4-dimethoxy-α-Pyrrolidinopropiophenone (hydrochloride) (Item No. 30034) is an analytical reference standard categorized as a cathinone. This product is intended for research and forensic applications.
Brand:CaymanSKU:30034 - 5 mgAvailable on backorder
3,4-Dimethoxyphenethylamine (hydrochloride) (Item No. 14141) is an analytical reference standard that is structurally categorized as a phenethylamine. It inhibits the deamination of tyramine (Item No. 18601) and tryptamine by rat brain monoamine oxidase.{33002} This product is intended for research and forensic applications.
Brand:CaymanSKU:- 3,4-Dimethoxyphenethylamine (hydrochloride) (Item No. 14141) is an analytical reference standard that is structurally categorized as a phenethylamine. It inhibits the deamination of tyramine (Item No. 18601) and tryptamine by rat brain monoamine oxidase.{33002} This product is intended for research and forensic applications.
Brand:CaymanSKU:-
3,4-DMMC (hydrochloride) (Item No. 9001098) is a potential designer drug with combined features of amphetamines, cathinones, and phenethylamines. It is structurally related to 4-methylmethcathinone, a psychoactive compound that has been identified in products sold as bath salts and plant food.{19498,19499,19497} This metabolite of 3,4-DMMC features conversion of the β-keto group to β-hydroxy and is an enantiomeric mixture of the R,S and S,R orientations at carbons one and two, as in ephedrine. The physiological and toxicological properties of this compound have not been elucidated. This product is intended for research and forensic applications.
Brand:CaymanSKU:9001431 - 1 mgAvailable on backorder
3,4-DMMC (hydrochloride) (Item No. 9001098) is a potential designer drug with combined features of amphetamines, cathinones, and phenethylamines. It is structurally related to 4-methylmethcathinone, a psychoactive compound that has been identified in products sold as bath salts and plant food.{19498,19499,19497} This metabolite of 3,4-DMMC features conversion of the β-keto group to β-hydroxy and is an enantiomeric mixture of the R,S and S,R orientations at carbons one and two, as in ephedrine. The physiological and toxicological properties of this compound have not been elucidated. This product is intended for research and forensic applications.
Brand:CaymanSKU:9001431 - 5 mgAvailable on backorder
3,4-DMMC (hydrochloride) (Item No. 9001098) is a potential designer drug with combined features of amphetamines, cathinones, and phenethylamines. It is structurally related to 4-methylmethcathinone, a psychoactive compound that has been identified in products sold as bath salts and plant food.{19498,19499,19497} This metabolite of 3,4-DMMC features conversion of the β-keto group to β-hydroxy and is an enantiomeric mixture of the R,S and S,R orientations at carbons one and two, as in ephedrine. The physiological and toxicological properties of this compound have not been elucidated. This product is intended for research and forensic applications.
Brand:CaymanSKU:9001431 - 500 µgAvailable on backorder
3,4-Dimethylmethcathinone (3,4-DMMC) (hydrochloride) ((±)-pseudoephedrine stereochemistry) (Item No. 9001098) is a potential designer drug with combined features of amphetamines, cathinones, and phenethylamines. It is structurally related to 4-methylmethcathinone, a psychoactive compound that has been identified in products sold as bath salts and plant food.{19498,19499,19497} This metabolite of 3,4-DMMC features conversion of the β-keto group to β-hydroxy and is an enantiomeric mixture of the R,R and S,S orientations at carbons one and two, as in pseudoephedrine. The physiological and toxicological properties of this compound have not been elucidated. This product is intended for research and forensic applications.
Brand:CaymanSKU:9001437 - 1 mgAvailable on backorder
3,4-Dimethylmethcathinone (3,4-DMMC) (hydrochloride) ((±)-pseudoephedrine stereochemistry) (Item No. 9001098) is a potential designer drug with combined features of amphetamines, cathinones, and phenethylamines. It is structurally related to 4-methylmethcathinone, a psychoactive compound that has been identified in products sold as bath salts and plant food.{19498,19499,19497} This metabolite of 3,4-DMMC features conversion of the β-keto group to β-hydroxy and is an enantiomeric mixture of the R,R and S,S orientations at carbons one and two, as in pseudoephedrine. The physiological and toxicological properties of this compound have not been elucidated. This product is intended for research and forensic applications.
Brand:CaymanSKU:9001437 - 5 mgAvailable on backorder
3,4-Dimethylmethcathinone (3,4-DMMC) (hydrochloride) ((±)-pseudoephedrine stereochemistry) (Item No. 9001098) is a potential designer drug with combined features of amphetamines, cathinones, and phenethylamines. It is structurally related to 4-methylmethcathinone, a psychoactive compound that has been identified in products sold as bath salts and plant food.{19498,19499,19497} This metabolite of 3,4-DMMC features conversion of the β-keto group to β-hydroxy and is an enantiomeric mixture of the R,R and S,S orientations at carbons one and two, as in pseudoephedrine. The physiological and toxicological properties of this compound have not been elucidated. This product is intended for research and forensic applications.
Brand:CaymanSKU:9001437 - 500 µgAvailable on backorder
3,4-Dimethylpyrazole (phosphate) (3,4-DMPP) is an inhibitor of nitrification deemed safe by extensive standard toxicology and ecotoxicology tests.{34653} When utilized on crops, 3,4-DMPP prevents nitrogen loss from soil, increases nitrogen use efficiency, and boosts crop yields.{34653,34654} However, a meta-analysis found no influence of 3,4-DMPP on net crop yield, although it may boost yields in alkaline soil.{34655} 3,4-DMPP may be less effective in acidic soils and in the post-harvest period.{34656,34657} DMPP interferes with ammonia monooxygenase from ammonia-oxidizing bacteria (AOB) and archaea (AOA) but may not directly affect AOB, AOA, and non-target populations.{34658}
Brand:CaymanSKU:21887 -Out of stock
3,4-Dimethylpyrazole (phosphate) (3,4-DMPP) is an inhibitor of nitrification deemed safe by extensive standard toxicology and ecotoxicology tests.{34653} When utilized on crops, 3,4-DMPP prevents nitrogen loss from soil, increases nitrogen use efficiency, and boosts crop yields.{34653,34654} However, a meta-analysis found no influence of 3,4-DMPP on net crop yield, although it may boost yields in alkaline soil.{34655} 3,4-DMPP may be less effective in acidic soils and in the post-harvest period.{34656,34657} DMPP interferes with ammonia monooxygenase from ammonia-oxidizing bacteria (AOB) and archaea (AOA) but may not directly affect AOB, AOA, and non-target populations.{34658}
Brand:CaymanSKU:21887 -Out of stock
3,4-Dimethylpyrazole (phosphate) (3,4-DMPP) is an inhibitor of nitrification deemed safe by extensive standard toxicology and ecotoxicology tests.{34653} When utilized on crops, 3,4-DMPP prevents nitrogen loss from soil, increases nitrogen use efficiency, and boosts crop yields.{34653,34654} However, a meta-analysis found no influence of 3,4-DMPP on net crop yield, although it may boost yields in alkaline soil.{34655} 3,4-DMPP may be less effective in acidic soils and in the post-harvest period.{34656,34657} DMPP interferes with ammonia monooxygenase from ammonia-oxidizing bacteria (AOB) and archaea (AOA) but may not directly affect AOB, AOA, and non-target populations.{34658}
Brand:CaymanSKU:21887 -Out of stock
3,4-Dimethylpyrazole (phosphate) (3,4-DMPP) is an inhibitor of nitrification deemed safe by extensive standard toxicology and ecotoxicology tests.{34653} When utilized on crops, 3,4-DMPP prevents nitrogen loss from soil, increases nitrogen use efficiency, and boosts crop yields.{34653,34654} However, a meta-analysis found no influence of 3,4-DMPP on net crop yield, although it may boost yields in alkaline soil.{34655} 3,4-DMPP may be less effective in acidic soils and in the post-harvest period.{34656,34657} DMPP interferes with ammonia monooxygenase from ammonia-oxidizing bacteria (AOB) and archaea (AOA) but may not directly affect AOB, AOA, and non-target populations.{34658}
Brand:CaymanSKU:21887 -Out of stock
3,4-DMA (hydrochloride) (Item No. 14142) is an analytical reference standard that is structurally categorized as an amphetamine. The physiological and toxicological properties of this compound are not known. This product is intended for research and forensic applications.
Brand:CaymanSKU:- 3,4-DMA (hydrochloride) (Item No. 14142) is an analytical reference standard that is structurally categorized as an amphetamine. The physiological and toxicological properties of this compound are not known. This product is intended for research and forensic applications.
Brand:CaymanSKU:-
3,4-Dimethoxymethamphetamine (3,4-DMMA) (hydrochloride) is an analog of 3,4-methylenedioxymethamphetamine (MDMA), a psychoactive drug and research chemical of the phenethylamine and amphetamine chemical classes. DMMA appears to interfere with monoamine transport, inhibiting uptake of noradrenalin and serotonin transporters (Kis = 22.8 and 7.7 μM, IC50s = 253.4 and 108 μM, respectively).{20483} DMMA is significantly less potent than MDMA (Kis = 0.6 and 2.5 μM; IC50s = 6.6 and 34.8 μM for MDMA inhibition of noradrenalin and serotonin transporters, respectively).{20483}
Brand:CaymanSKU:11128 - 10 mgAvailable on backorder
3,4-Dimethoxymethamphetamine (3,4-DMMA) (hydrochloride) is an analog of 3,4-methylenedioxymethamphetamine (MDMA), a psychoactive drug and research chemical of the phenethylamine and amphetamine chemical classes. DMMA appears to interfere with monoamine transport, inhibiting uptake of noradrenalin and serotonin transporters (Kis = 22.8 and 7.7 μM, IC50s = 253.4 and 108 μM, respectively).{20483} DMMA is significantly less potent than MDMA (Kis = 0.6 and 2.5 μM; IC50s = 6.6 and 34.8 μM for MDMA inhibition of noradrenalin and serotonin transporters, respectively).{20483}
Brand:CaymanSKU:11128 - 5 mgAvailable on backorder
3,4-Dimethoxymethamphetamine (3,4-DMMA) (hydrochloride) is an analog of 3,4-methylenedioxymethamphetamine (MDMA), a psychoactive drug and research chemical of the phenethylamine and amphetamine chemical classes. DMMA appears to interfere with monoamine transport, inhibiting uptake of noradrenalin and serotonin transporters (Kis = 22.8 and 7.7 μM, IC50s = 253.4 and 108 μM, respectively).{20483} DMMA is significantly less potent than MDMA (Kis = 0.6 and 2.5 μM; IC50s = 6.6 and 34.8 μM for MDMA inhibition of noradrenalin and serotonin transporters, respectively).{20483}
Brand:CaymanSKU:11128 - 50 mgAvailable on backorder
Methylone (Item No. 10986) is designer cathinone that is structurally similar to the illicit, psychotropic drug 3,4-MDMA (Item No. 13971).{20370,20369} 3,4-EDMC is an analog of methylone. The physiological and toxicological properties of this compound are not known. This product is intended for forensic and research purposes.
Brand:CaymanSKU:- Methylone (Item No. 10986) is designer cathinone that is structurally similar to the illicit, psychotropic drug 3,4-MDMA (Item No. 13971).{20370,20369} 3,4-EDMC is an analog of methylone. The physiological and toxicological properties of this compound are not known. This product is intended for forensic and research purposes.
Brand:CaymanSKU:-