Chemicals

Showing 4951–5100 of 41137 results

  • 25I-NBMD is a derivative of the phenethylamine hallucinogen 2C-I, characterized by the addition of a methylenedioxy-benzyl group to the amine. This addition increases the affinity (Ki = 0.049–0.21 nM) and activity (EC50 = 8.2 nM) at the serotonin receptor 5-HT2A.{21331,20442} This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:11947 - 1 mg

    Available on backorder

  • 25I-NBMD is a derivative of the phenethylamine hallucinogen 2C-I, characterized by the addition of a methylenedioxy-benzyl group to the amine. This addition increases the affinity (Ki = 0.049–0.21 nM) and activity (EC50 = 8.2 nM) at the serotonin receptor 5-HT2A.{21331,20442} This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:11947 - 10 mg

    Available on backorder

  • 25I-NBMD is a derivative of the phenethylamine hallucinogen 2C-I, characterized by the addition of a methylenedioxy-benzyl group to the amine. This addition increases the affinity (Ki = 0.049–0.21 nM) and activity (EC50 = 8.2 nM) at the serotonin receptor 5-HT2A.{21331,20442} This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:11947 - 5 mg

    Available on backorder

  • 25I-NBOH is a derivative of the phenethylamine hallucinogen 2C-I (Item No. 11113) with an N-(2-hydroxybenzyl) addition at the amine. It can act as a potent agonist for the human serotonin 5-HT2A receptor (Ki = 0.061 nM) with 12-fold greater potency compared to 2C-I itself.{20442,21331} This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:-
  • 25I-NBOH is a derivative of the phenethylamine hallucinogen 2C-I (Item No. 11113) with an N-(2-hydroxybenzyl) addition at the amine. It can act as a potent agonist for the human serotonin 5-HT2A receptor (Ki = 0.061 nM) with 12-fold greater potency compared to 2C-I itself.{20442,21331} This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:-
  • 25I-NBOH is a derivative of the phenethylamine hallucinogen 2C-I (Item No. 11113) with an N-(2-hydroxybenzyl) addition at the amine. It can act as a potent agonist for the human serotonin 5-HT2A receptor (Ki = 0.061 nM) with 12-fold greater potency compared to 2C-I itself.{20442,21331} This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:-
  • 25I-NBOMe, a derivative of the serotonin 2A (5-HT2A) receptor agonist 2C-I, is 16-fold more potent than 2C-I with a Ki value of 0.044 nM for human 5-HT2A receptors.{20442,20443} 25I-NBOMe 3-methoxy isomer differs from 25I-NBOMe by having a methoxy group at the three, rather than two, position on the benzene ring. The properties of this compound have not been evaluated. This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:-
  • 25I-NBOMe, a derivative of the serotonin 2A (5-HT2A) receptor agonist 2C-I, is 16-fold more potent than 2C-I with a Ki value of 0.044 nM for human 5-HT2A receptors.{20442,20443} 25I-NBOMe 3-methoxy isomer differs from 25I-NBOMe by having a methoxy group at the three, rather than two, position on the benzene ring. The properties of this compound have not been evaluated. This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:-
  • 25I-NBOMe, a derivative of the serotonin 2A (5-HT2A) receptor agonist 2C-I, is 16-fold more potent than 2C-I with a Ki value of 0.044 nM for human 5-HT2A receptors.{20442,20443} 25I-NBOMe 3-methoxy isomer differs from 25I-NBOMe by having a methoxy group at the three, rather than two, position on the benzene ring. The properties of this compound have not been evaluated. This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:-
  • 25I-NBOMe, a derivative of the serotonin 2A (5-HT2A) receptor agonist 2C-I, is 16-fold more potent than 2C-I with a Ki value of 0.044 nM for human 5-HT2A receptors.{20442,20443} 25I-NBOMe 4-methoxy isomer differs from 25I-NBOMe by having a methoxy group at the four, rather than two, position on the benzene ring. The properties of this compound have not been evaluated. This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:-
  • 25I-NBOMe, a derivative of the serotonin 2A (5-HT2A) receptor agonist 2C-I, is 16-fold more potent than 2C-I with a Ki value of 0.044 nM for human 5-HT2A receptors.{20442,20443} 25I-NBOMe 4-methoxy isomer differs from 25I-NBOMe by having a methoxy group at the four, rather than two, position on the benzene ring. The properties of this compound have not been evaluated. This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:-
  • 25I-NBOMe, a derivative of the serotonin 2A (5-HT2A) receptor agonist 2C-I, is 16-fold more potent than 2C-I with a Ki value of 0.044 nM for human 5-HT2A receptors.{20442,20443} 25I-NBOMe 4-methoxy isomer differs from 25I-NBOMe by having a methoxy group at the four, rather than two, position on the benzene ring. The properties of this compound have not been evaluated. This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:-
  • 2C-N (Item No. 11890) is described formally as 2,5-dimethoxy-4-nitrophenethylamine and is structurally analogous to the psychedelic drug 2C-B (Item No. 11734). 2C-N potently stimulates arachidonic acid (Item No. 90010) release through the serotonin receptors 5-HT2C (pEC50 = 5.91) and 5-HT2A (pEC50 = 4.78).{20772} 25N-NBOMe is a derivative of 2C-N having an N-(2-methoxybenzyl) addition at the amine. For similar dimethoxyphenethylamines including 2C-B, this N-(2-methoxybenzyl) addition significantly increases activity at the serotonin receptor.{20443} This product is intended for forensic and research uses.  

     

    Brand:
    Cayman
    SKU:-
  • 2C-N (Item No. 11890) is described formally as 2,5-dimethoxy-4-nitrophenethylamine and is structurally analogous to the psychedelic drug 2C-B (Item No. 11734). 2C-N potently stimulates arachidonic acid (Item No. 90010) release through the serotonin receptors 5-HT2C (pEC50 = 5.91) and 5-HT2A (pEC50 = 4.78).{20772} 25N-NBOMe is a derivative of 2C-N having an N-(2-methoxybenzyl) addition at the amine. For similar dimethoxyphenethylamines including 2C-B, this N-(2-methoxybenzyl) addition significantly increases activity at the serotonin receptor.{20443} This product is intended for forensic and research uses.  

     

    Brand:
    Cayman
    SKU:-
  • 2C-N (Item No. 11890) is described formally as 2,5-dimethoxy-4-nitrophenethylamine and is structurally analogous to the psychedelic drug 2C-B (Item No. 11734). 2C-N potently stimulates arachidonic acid (Item No. 90010) release through the serotonin receptors 5-HT2C (pEC50 = 5.91) and 5-HT2A (pEC50 = 4.78).{20772} 25N-NBOMe is a derivative of 2C-N having an N-(2-methoxybenzyl) addition at the amine. For similar dimethoxyphenethylamines including 2C-B, this N-(2-methoxybenzyl) addition significantly increases activity at the serotonin receptor.{20443} This product is intended for forensic and research uses.  

     

    Brand:
    Cayman
    SKU:-
  • 2C-N (Item No. 11890) is described formally as 2,5-dimethoxy-4-nitrophenethylamine and is structurally analogous to the psychedelic drug 2C-B (Item No. 11734). 2C-N potently stimulates arachidonic acid (Item No. 90010) release through the serotonin receptors 5-HT2C (pEC50 = 5.91) and 5-HT2A (pEC50 = 4.78).{20772} 25N-NBOMe is a derivative of 2C-N having an N-(2-methoxybenzyl) addition at the amine. For similar dimethoxyphenethylamines including 2C-B, this N-(2-methoxybenzyl) addition significantly increases activity at the serotonin receptor.{20443} This product is intended for forensic and research uses.  

     

    Brand:
    Cayman
    SKU:-
  • 25P-NBOMe (hydrochloride) (Item No. 9001991) is an analytical reference standard that is structurally categorized as a phenethylamine. It binds serotonin (5-HT) receptors 5-HT2A and 5-HT2C with similar affinities (pKis = ~9 for both).{26036} This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:9001991 - 1 mg

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  • 25P-NBOMe (hydrochloride) (Item No. 9001991) is an analytical reference standard that is structurally categorized as a phenethylamine. It binds serotonin (5-HT) receptors 5-HT2A and 5-HT2C with similar affinities (pKis = ~9 for both).{26036} This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:9001991 - 5 mg

    Available on backorder

  • 25P-NBOMe (hydrochloride) (Item No. 9001991) is an analytical reference standard that is structurally categorized as a phenethylamine. It binds serotonin (5-HT) receptors 5-HT2A and 5-HT2C with similar affinities (pKis = ~9 for both).{26036} This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:9001991 - 50 mg

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  • 2C-T is a 2,5-dimethoxy phenethylamine that has structural and pharmacokinetic properties similar to the psychedelic mescaline.{21906} 25T-NBOMe is a derivative of 2C-T having an N-(2-methoxybenzyl) addition at the amine. This addition on related phenethylamines increases the affinity and selectivity for the 5-HT2A receptor over other serotonin receptors.{20442} This product is intended for forensic and research purposes.  

     

    Brand:
    Cayman
    SKU:-
  • 2C-T is a 2,5-dimethoxy phenethylamine that has structural and pharmacokinetic properties similar to the psychedelic mescaline.{21906} 25T-NBOMe is a derivative of 2C-T having an N-(2-methoxybenzyl) addition at the amine. This addition on related phenethylamines increases the affinity and selectivity for the 5-HT2A receptor over other serotonin receptors.{20442} This product is intended for forensic and research purposes.  

     

    Brand:
    Cayman
    SKU:-
  • 2C-T is a 2,5-dimethoxy phenethylamine that has structural and pharmacokinetic properties similar to the psychedelic mescaline.{21906} 25T-NBOMe is a derivative of 2C-T having an N-(2-methoxybenzyl) addition at the amine. This addition on related phenethylamines increases the affinity and selectivity for the 5-HT2A receptor over other serotonin receptors.{20442} This product is intended for forensic and research purposes.  

     

    Brand:
    Cayman
    SKU:-
  • 2C-T is a 2,5-dimethoxy phenethylamine that has structural and pharmacokinetic properties similar to the psychedelic mescaline.{21906} 25T-NBOMe is a derivative of 2C-T having an N-(2-methoxybenzyl) addition at the amine. This addition on related phenethylamines increases the affinity and selectivity for the 5-HT2A receptor over other serotonin receptors.{20442} This product is intended for forensic and research purposes.  

     

    Brand:
    Cayman
    SKU:-
  • 2C-T-4 (Item No. 11892) is described formally as 2,5-dimethoxy-4-(isopropylthio)phenethylamine. The physiological and toxicological effects of this designer drug have not been investigated, although there is a case report of 2C-T-4 causing acute psychosis.{21280} 25T4-NBOMe is a derivative of 2C-T-4, characterized by the addition of a benzyl-methoxy (BOMe) group to the amine. While the properties of this compound are not known, the N-(2-methoxybenzyl) addition significantly increases the affinity and activity of other disubstituted phenethylamines at the serotonin receptor 5-HT2A.{20442,20443} This product is intended for forensic and research applications.  

     

    Brand:
    Cayman
    SKU:9001989 - 1 mg

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  • 2C-T-4 (Item No. 11892) is described formally as 2,5-dimethoxy-4-(isopropylthio)phenethylamine. The physiological and toxicological effects of this designer drug have not been investigated, although there is a case report of 2C-T-4 causing acute psychosis.{21280} 25T4-NBOMe is a derivative of 2C-T-4, characterized by the addition of a benzyl-methoxy (BOMe) group to the amine. While the properties of this compound are not known, the N-(2-methoxybenzyl) addition significantly increases the affinity and activity of other disubstituted phenethylamines at the serotonin receptor 5-HT2A.{20442,20443} This product is intended for forensic and research applications.  

     

    Brand:
    Cayman
    SKU:9001989 - 10 mg

    Available on backorder

  • 2C-T-4 (Item No. 11892) is described formally as 2,5-dimethoxy-4-(isopropylthio)phenethylamine. The physiological and toxicological effects of this designer drug have not been investigated, although there is a case report of 2C-T-4 causing acute psychosis.{21280} 25T4-NBOMe is a derivative of 2C-T-4, characterized by the addition of a benzyl-methoxy (BOMe) group to the amine. While the properties of this compound are not known, the N-(2-methoxybenzyl) addition significantly increases the affinity and activity of other disubstituted phenethylamines at the serotonin receptor 5-HT2A.{20442,20443} This product is intended for forensic and research applications.  

     

    Brand:
    Cayman
    SKU:9001989 - 5 mg

    Available on backorder

  • 2C-T-4 (Item No. 11892) is described formally as 2,5-dimethoxy-4-(isopropylthio)phenethylamine. The physiological and toxicological effects of this designer drug have not been investigated, although there is a case report of 2C-T-4 causing acute psychosis.{21280} 25T4-NBOMe is a derivative of 2C-T-4, characterized by the addition of a benzyl-methoxy (BOMe) group to the amine. While the properties of this compound are not known, the N-(2-methoxybenzyl) addition significantly increases the affinity and activity of other disubstituted phenethylamines at the serotonin receptor 5-HT2A.{20442,20443} This product is intended for forensic and research applications.  

     

    Brand:
    Cayman
    SKU:9001989 - 50 mg

    Available on backorder

  • 27-alkyne Cholesterol is an alkyne derivative of cholesterol. It has been used to track cholesterol metabolism and localization using click chemistry and various reporter azides in fixed or living cells.{24756} It is a substrate for enzymes from a variety of species including bacteria, yeast, rat, and human.  

     

    Brand:
    Cayman
    SKU:24319 - 100 µg

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  • 27-alkyne Cholesterol is an alkyne derivative of cholesterol. It has been used to track cholesterol metabolism and localization using click chemistry and various reporter azides in fixed or living cells.{24756} It is a substrate for enzymes from a variety of species including bacteria, yeast, rat, and human.  

     

    Brand:
    Cayman
    SKU:24319 - 250 µg

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  • 27-alkyne Cholesterol is an alkyne derivative of cholesterol. It has been used to track cholesterol metabolism and localization using click chemistry and various reporter azides in fixed or living cells.{24756} It is a substrate for enzymes from a variety of species including bacteria, yeast, rat, and human.  

     

    Brand:
    Cayman
    SKU:24319 - 500 µg

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  • 27-hydroxy Cholestenone is an oxysterol.{42668} Levels of 27-hydroxy cholestenone are increased in Cyp46a-/- mouse brain. 27-hydroxy Cholestenone has been used as an intermediate in the synthesis of dafachronic acid ligands for the DAF-12 nuclear hormone receptor.{22014}  

     

    Brand:
    Cayman
    SKU:25550 - 1 mg

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  • 27-hydroxy Cholestenone is an oxysterol.{42668} Levels of 27-hydroxy cholestenone are increased in Cyp46a-/- mouse brain. 27-hydroxy Cholestenone has been used as an intermediate in the synthesis of dafachronic acid ligands for the DAF-12 nuclear hormone receptor.{22014}  

     

    Brand:
    Cayman
    SKU:25550 - 10 mg

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  • 27-hydroxy Cholestenone is an oxysterol.{42668} Levels of 27-hydroxy cholestenone are increased in Cyp46a-/- mouse brain. 27-hydroxy Cholestenone has been used as an intermediate in the synthesis of dafachronic acid ligands for the DAF-12 nuclear hormone receptor.{22014}  

     

    Brand:
    Cayman
    SKU:25550 - 5 mg

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  • 27-hydroxy Heptacosanoic acid methyl ester is a hydroxylated fatty acid methyl ester form of heptacosanoic acid. [Matreya, LLC. Catalog No. 1883]  

     

    Brand:
    Cayman
    SKU:24657 - 10 mg

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  • 27-hydroxy Heptacosanoic acid methyl ester is a hydroxylated fatty acid methyl ester form of heptacosanoic acid. [Matreya, LLC. Catalog No. 1883]  

     

    Brand:
    Cayman
    SKU:24657 - 25 mg

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  • 27-hydroxy Heptacosanoic acid methyl ester is a hydroxylated fatty acid methyl ester form of heptacosanoic acid. [Matreya, LLC. Catalog No. 1883]  

     

    Brand:
    Cayman
    SKU:24657 - 5 mg

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  • A series of 2,5-dimethoxyphenethylamines, collectively referred to as 2Cs, have psychoactive effects.{20685,20772} The most effective 2C compounds are substituted at the 4 position of the aromatic ring; many are scheduled as illegal substances. 2C-B is described formally as 4-bromo-2,5-dimethoxy phenethylamine. This hallucinogenic designer drug activates the serotonin receptor 5-HT2C (pEC50 = 6.8 for arachidonic acid release).{20772} Its metabolism has been reviewed.{19963} LC-MS/MS screening methods for identifying this compound in serum have been developed.{21281} This product is intended for forensic and research purposes.  

     

    Brand:
    Cayman
    SKU:-
  • A group of phenethylamine derivatives referred to as the FLY compounds, named for their insect-like appearance of two “wing-like” furan or dihydrofuran rings fused on the opposite sides of the central benzene ring, have been identified with allegedly potent hallucinogenic effects.{21377} 2C-B-fly is the dihydrodifuran analog of the Schedule I hallucinogen 4-bromo-2,5-dimethoxyphenethylamine (2C-B).{21377,21380} It is expected to show similar activity to 2C-B, which acts as a partial agonist at the 5-HT2A serotonin receptor and demonstrates high binding affinity for the 5-HT2B and 5-HT2C serotonin receptors.{21379,21376} This product is intended for forensic and research purposes.  

     

    Brand:
    Cayman
    SKU:11473 - 1 mg

    Available on backorder

  • A group of phenethylamine derivatives referred to as the FLY compounds, named for their insect-like appearance of two “wing-like” furan or dihydrofuran rings fused on the opposite sides of the central benzene ring, have been identified with allegedly potent hallucinogenic effects.{21377} 2C-B-fly is the dihydrodifuran analog of the Schedule I hallucinogen 4-bromo-2,5-dimethoxyphenethylamine (2C-B).{21377,21380} It is expected to show similar activity to 2C-B, which acts as a partial agonist at the 5-HT2A serotonin receptor and demonstrates high binding affinity for the 5-HT2B and 5-HT2C serotonin receptors.{21379,21376} This product is intended for forensic and research purposes.  

     

    Brand:
    Cayman
    SKU:11473 - 10 mg

    Available on backorder

  • A group of phenethylamine derivatives referred to as the FLY compounds, named for their insect-like appearance of two “wing-like” furan or dihydrofuran rings fused on the opposite sides of the central benzene ring, have been identified with allegedly potent hallucinogenic effects.{21377} 2C-B-fly is the dihydrodifuran analog of the Schedule I hallucinogen 4-bromo-2,5-dimethoxyphenethylamine (2C-B).{21377,21380} It is expected to show similar activity to 2C-B, which acts as a partial agonist at the 5-HT2A serotonin receptor and demonstrates high binding affinity for the 5-HT2B and 5-HT2C serotonin receptors.{21379,21376} This product is intended for forensic and research purposes.  

     

    Brand:
    Cayman
    SKU:11473 - 5 mg

    Available on backorder

  • A series of 2,5-dimethoxyphenethylamines, collectively referred to as 2Cs, have psychoactive effects.{20685,20772} The most effective 2C compounds are substituted at the four position of the aromatic ring. Many are scheduled as illegal substances. {19963,19758} 2C-C is described formally as 2,5-dimethoxy-4-chlorophenethylamine. A known hallucinogen, this compound stimulates monoamine receptor activity and inhibits the re-uptake of serotonin and norepinephrine in rat brain synaptosomes (IC50s = 31 and 63 μM, respectively).{19271,19758} LC-MS/MS screening methods for this designer drug have been developed.{21281} This product is intended for forensic and research purposes.  

     

    Brand:
    Cayman
    SKU:-
  • A series of 2,5-dimethoxyphenethylamines, collectively referred to as 2Cs, have psychoactive effects.{20685,20772} The most effective 2C compounds are substituted at the four position of the aromatic ring. Many are scheduled as illegal substances.{19963,19758} 2C-D is described formally as 2,5-dimethoxy-4-methylphenethylamine. It is a weak agonist of serotonin (5-HT; Item No. 14332) receptors (pEC50s = 5.09 and 4.73 for 5-HT2A and 5-HT2C, respectively).{20772} Its metabolism in rats has been described.{19963} LC-MS/MS screening methods for this designer drug have been developed.{21281} This product is intended for forensic and research purposes.  

     

    Brand:
    Cayman
    SKU:-
  • 2C-E (hydrochloride) (exempt preparation) (Item No. 15699) is an analytical reference standard categorized as a phenethylamine.{19758} 2C-E has been detected in capsules and powder seized by law enforcement.{48178,48179,19963} 2C-E is regulated as a Schedule I compound in the United States. 2C-E (hydrochloride) (exempt preparation) (Item No. 15699) is provided as a DEA exempt preparation. This product is intended for research and forensic applications.  

     

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    Cayman
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  • A series of 2,5-phenethylamines, collectively referred to as 2Cs, have psychoactive effects.{20685,20772} The most effective 2C compounds are 2,5-dimethoxy-4-substituted phenethylamines; many are scheduled as illegal substances.{19963,19758} 2C-H is described formally as 2,5-dimethoxyphenethylamine. Unlike the 4-substituted 2-C forms, it has little effect on serotonin receptors, activating the 5-HT2C receptor to 20% that induced by serotonin (pEC50 = 5.93).{20772} This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:-
  • A series of 2,5-phenethylamines, collectively referred to as 2Cs, have psychoactive effects; many are scheduled as illegal substances. 2C-I (hydrochloride) is described formally as 2,5-dimethoxy-4-iodophenethylamine. 2C-I (hydrochloride) is described formally as 2,5-dimethoxy-4-iodophenethylamine. Like other 2Cs, 2C-I (hydrochloride) is a monoamine oxidase inhibitor, blocking the breakdown of serotonin and norepinephrine (IC50 values of 79 and 37 μM, respectively), but not dopamine.{19758} Its metabolism has been described.{19963} This product is intended for forensic applications.  

     

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    Cayman
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  • 2C-iP (hydrochloride) (Item No. 18281) is an analytical reference standard that is classified as a phenethylamine. The physiological and toxicological properties of this compound have not been investigated. This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:-

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  • 2C-iP (hydrochloride) (Item No. 18281) is an analytical reference standard that is classified as a phenethylamine. The physiological and toxicological properties of this compound have not been investigated. This product is intended for research and forensic applications.  

     

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    Cayman
    SKU:-

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  • 2C-iP (hydrochloride) (Item No. 18281) is an analytical reference standard that is classified as a phenethylamine. The physiological and toxicological properties of this compound have not been investigated. This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:-

    Available on backorder

  • A series of 2,5-phenethylamines, collectively referred to as 2Cs, have psychoactive effects.{20685,20772} The most effective 2C compounds are 2,5-dimethoxy-4-substituted phenethylamines; many are regulated as illegal substances.{19963,19758} 2C-N is described formally as 2,5-dimethoxy-4-nitrophenethylamine and is structurally analogous to the psychedelic drug 2C-B. 2C-N potently stimulates arachidonic acid release through the serotonin receptors 5-HT2C (pEC50 = 5.91) and 5-HT2A (pEC50 = 4.78).{20772} This product is intended for forensic and research applications.  

     

    Brand:
    Cayman
    SKU:-
  • A series of 2,5-dimethoxy phenethylamines, collectively referred to as 2Cs, have psychoactive effects.{20685,20772} The most effective 2C compounds are substituted at the four position of the aromatic ring; many are scheduled as illegal substances.{19963,19758} 2C-P is described formally as 2,5-dimethoxy-4-propylphenethylamine and is structurally analogous to the psychedelic drug 2C-B. The physiological and toxicological properties of this compound are not known. LC-MS/MS screening methods for this designer drug have been developed.{21281} This product is intended for forensic and research purposes.  

     

    Brand:
    Cayman
    SKU:-
  • A series of 2,5-dimethoxy phenethylamines, collectively referred to as 2Cs, have psychoactive effects.{20685,20772} The most effective 2C compounds are substituted at the 4 position of the aromatic ring. Many are scheduled as illegal substances.{19963,19758} 2C-T (hydrochloride) is described formally as 2,5-dimethoxy-4-methylthiophenylethylamine hydrochloride. It has structural and pharmacokinetic properties similar to the drugs mescaline (hydrochloride) (Item No. 11950) and 2C-T-2 (hydrochloride) (Item No. 11891).{21906} This product is intended for forensic and research purposes.  

     

    Brand:
    Cayman
    SKU:-
  • A series of 2,5-dimethoxy phenethylamines, collectively referred to as 2Cs, have psychoactive effects.{20685,20772} The most effective 2C compounds are substituted at the 4 position of the aromatic ring. Many are scheduled as illegal substances.{19963,19758} 2C-T (hydrochloride) is described formally as 2,5-dimethoxy-4-methylthiophenylethylamine hydrochloride. It has structural and pharmacokinetic properties similar to the drugs mescaline (hydrochloride) (Item No. 11950) and 2C-T-2 (hydrochloride) (Item No. 11891).{21906} This product is intended for forensic and research purposes.  

     

    Brand:
    Cayman
    SKU:-
  • A series of 2,5-dimethoxy phenethylamines, collectively referred to as 2Cs, have psychoactive effects.{20685,20772} The most effective 2C compounds are substituted at the 4 position of the aromatic ring. Many are scheduled as illegal substances.{19963,19758} 2C-T (hydrochloride) is described formally as 2,5-dimethoxy-4-methylthiophenylethylamine hydrochloride. It has structural and pharmacokinetic properties similar to the drugs mescaline (hydrochloride) (Item No. 11950) and 2C-T-2 (hydrochloride) (Item No. 11891).{21906} This product is intended for forensic and research purposes.  

     

    Brand:
    Cayman
    SKU:-
  • A series of 2,5-dimethoxy phenethylamines, collectively referred to as 2Cs, have psychoactive effects.{20685,20772} The most effective 2C compounds are substituted at the four position of the aromatic ring. 2C-T-2 is described formally as 2,5-dimethoxy-4-ethylthiophenethylamine. Its metabolism has been described.{19963} LC-MS/MS screening methods for this designer drug have been developed.{21281} This product is intended for forensic and research purposes.  

     

    Brand:
    Cayman
    SKU:-
  • A series of 2,5-dimethoxy phenethylamines, collectively referred to as 2Cs, have psychoactive effects.{20685,20772} The most effective 2C compounds are substituted at the 4 position of the aromatic ring. 2C-T-4 is described formally as 2,5-dimethoxy-4-(isopropylthio)phenethylamine. The physiological and toxicological effects of this compound have not been investigated, although there is a case report of 2C-T-4 causing acute psychosis.{21280} LC-MS/MS screening methods for this designer drug have been developed.{21281} This product is intended for forensic and research purposes.  

     

    Brand:
    Cayman
    SKU:-
  • A series of 2,5-dimethoxy phenethylamines, collectively referred to as 2Cs, have psychoactive effects.{20685,20772} The most effective 2C compounds are substituted at the four position of the aromatic ring. 2C-T-7 is a 2,5-dimethoxy phenethylamine with a propylthio group in the four position. Its metabolism has been described.{19963} LC-MS/MS screening methods for this designer drug have been developed.{21281} This product is intended for forensic and research purposes.  

     

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    Cayman
    SKU:-
  • A series of 2,5-dimethoxyphenethylamines, collectively referred to as 2Cs, have psychoactive effects.{20685,20772} The most effective 2C compounds are substituted at the 4 position of the aromatic ring; many are scheduled as illegal substances.{19963,19758} 2C-TFM is a 2C compound with a para-trifluoromethyl substitution. It is a potent agonist of the serotonin (5-HT) receptor subtypes 5-HT2A and 5-HT2C (Kaff = 165 and 32 nM).{25664} This product is intended for forensic and research purposes.  

     

    Brand:
    Cayman
    SKU:-
  • A series of 2,5-dimethoxyphenethylamines, collectively referred to as 2Cs, have psychoactive effects.{20685,20772} The most effective 2C compounds are substituted at the 4 position of the aromatic ring; many are scheduled as illegal substances.{19963,19758} 2C-TFM is a 2C compound with a para-trifluoromethyl substitution. It is a potent agonist of the serotonin (5-HT) receptor subtypes 5-HT2A and 5-HT2C (Kaff = 165 and 32 nM).{25664} This product is intended for forensic and research purposes.  

     

    Brand:
    Cayman
    SKU:-
  • A series of 2,5-dimethoxyphenethylamines, collectively referred to as 2Cs, have psychoactive effects.{20685,20772} The most effective 2C compounds are substituted at the 4 position of the aromatic ring; many are scheduled as illegal substances.{19963,19758} 2C-TFM is a 2C compound with a para-trifluoromethyl substitution. It is a potent agonist of the serotonin (5-HT) receptor subtypes 5-HT2A and 5-HT2C (Kaff = 165 and 32 nM).{25664} This product is intended for forensic and research purposes.  

     

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    Cayman
    SKU:-
  • 2F-Peracetyl-fucose is an inhibitor of protein fucosylation.{57065} It inhibits fucosylation of IgG1 monoclonal antibodies produced by CHO-DG44 cells when used at a concentration of 50 µM. It reduces intracellular GDP-fucose levels in CHO-DG44 cells in a concentration-dependent manner. 2F-Peracetyl-fucose (100 µM) also decreases intracellular fucose levels in A. thaliana seedlings.{57066} 2F-Peracetyl-fucose decreases root length in A. thaliana seedlings in a concentration-dependent manner.  

     

    Brand:
    Cayman
    SKU:30865 - 100 mg

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  • 2F-Peracetyl-fucose is an inhibitor of protein fucosylation.{57065} It inhibits fucosylation of IgG1 monoclonal antibodies produced by CHO-DG44 cells when used at a concentration of 50 µM. It reduces intracellular GDP-fucose levels in CHO-DG44 cells in a concentration-dependent manner. 2F-Peracetyl-fucose (100 µM) also decreases intracellular fucose levels in A. thaliana seedlings.{57066} 2F-Peracetyl-fucose decreases root length in A. thaliana seedlings in a concentration-dependent manner.  

     

    Brand:
    Cayman
    SKU:30865 - 250 mg

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  • 2F-Peracetyl-fucose is an inhibitor of protein fucosylation.{57065} It inhibits fucosylation of IgG1 monoclonal antibodies produced by CHO-DG44 cells when used at a concentration of 50 µM. It reduces intracellular GDP-fucose levels in CHO-DG44 cells in a concentration-dependent manner. 2F-Peracetyl-fucose (100 µM) also decreases intracellular fucose levels in A. thaliana seedlings.{57066} 2F-Peracetyl-fucose decreases root length in A. thaliana seedlings in a concentration-dependent manner.  

     

    Brand:
    Cayman
    SKU:30865 - 50 mg

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  • 2H-Cho-Arg is a steroid-based cationic lipid that contains a 2H-cholesterol skeleton coupled to an L-arginine head group and can be used to facilitate gene transfection.{44005} It forms a complex with plasmid DNA (pDNA) and decreases pDNA migration in an electrophoretic mobility shift assay at +/- charge ratios of 4 or higher. 2H-Cho-Arg facilitates transfection of a luciferase gene into H1299 cells, an effect that is reversed by the lipid raft-mediated endocytosis inhibitor methyl-β-cyclodextrin (Item No. 21633) and the caveolae-mediated endocytosis inhibitor genistein (Item No. 10005167), but not by inhibitors of clathrin- or micropinocytosis-mediated endocytosis. It induces cytotoxicity in H1299 cells (IC50 = 92.7 μg/ml).  

     

    Brand:
    Cayman
    SKU:25944 - 1 mg

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  • 2H-Cho-Arg is a steroid-based cationic lipid that contains a 2H-cholesterol skeleton coupled to an L-arginine head group and can be used to facilitate gene transfection.{44005} It forms a complex with plasmid DNA (pDNA) and decreases pDNA migration in an electrophoretic mobility shift assay at +/- charge ratios of 4 or higher. 2H-Cho-Arg facilitates transfection of a luciferase gene into H1299 cells, an effect that is reversed by the lipid raft-mediated endocytosis inhibitor methyl-β-cyclodextrin (Item No. 21633) and the caveolae-mediated endocytosis inhibitor genistein (Item No. 10005167), but not by inhibitors of clathrin- or micropinocytosis-mediated endocytosis. It induces cytotoxicity in H1299 cells (IC50 = 92.7 μg/ml).  

     

    Brand:
    Cayman
    SKU:25944 - 10 mg

    Available on backorder

  • 2H-Cho-Arg is a steroid-based cationic lipid that contains a 2H-cholesterol skeleton coupled to an L-arginine head group and can be used to facilitate gene transfection.{44005} It forms a complex with plasmid DNA (pDNA) and decreases pDNA migration in an electrophoretic mobility shift assay at +/- charge ratios of 4 or higher. 2H-Cho-Arg facilitates transfection of a luciferase gene into H1299 cells, an effect that is reversed by the lipid raft-mediated endocytosis inhibitor methyl-β-cyclodextrin (Item No. 21633) and the caveolae-mediated endocytosis inhibitor genistein (Item No. 10005167), but not by inhibitors of clathrin- or micropinocytosis-mediated endocytosis. It induces cytotoxicity in H1299 cells (IC50 = 92.7 μg/ml).  

     

    Brand:
    Cayman
    SKU:25944 - 5 mg

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  • 2S-Eriodictyol a flavanone that has been found in Citrus and has antioxidant activity.{61132} It is protective against hydrogen peroxide-induced cell injury and apoptosis in EA.hy926 cells when used at a concentration of 20 µM.  

     

    Brand:
    Cayman
    SKU:26803 - 1 mg

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  • 2S-Eriodictyol a flavanone that has been found in Citrus and has antioxidant activity.{61132} It is protective against hydrogen peroxide-induced cell injury and apoptosis in EA.hy926 cells when used at a concentration of 20 µM.  

     

    Brand:
    Cayman
    SKU:26803 - 10 mg

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  • 2S-Eriodictyol a flavanone that has been found in Citrus and has antioxidant activity.{61132} It is protective against hydrogen peroxide-induced cell injury and apoptosis in EA.hy926 cells when used at a concentration of 20 µM.  

     

    Brand:
    Cayman
    SKU:26803 - 25 mg

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  • 2S-Eriodictyol a flavanone that has been found in Citrus and has antioxidant activity.{61132} It is protective against hydrogen peroxide-induced cell injury and apoptosis in EA.hy926 cells when used at a concentration of 20 µM.  

     

    Brand:
    Cayman
    SKU:26803 - 5 mg

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  • 2α-Mannobiose is a disaccharide composed of two mannose molecules linked by a 1-2 glycosidic bond.{38349} It has been immobilized on monolithic capillary columns for the affinity purification of mannose binding proteins.{38350}  

     

    Brand:
    Cayman
    SKU:21848 -

    Out of stock

  • 2α-Mannobiose is a disaccharide composed of two mannose molecules linked by a 1-2 glycosidic bond.{38349} It has been immobilized on monolithic capillary columns for the affinity purification of mannose binding proteins.{38350}  

     

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    Cayman
    SKU:21848 -

    Out of stock

  • 2α-Mannobiose is a disaccharide composed of two mannose molecules linked by a 1-2 glycosidic bond.{38349} It has been immobilized on monolithic capillary columns for the affinity purification of mannose binding proteins.{38350}  

     

    Brand:
    Cayman
    SKU:21848 -

    Out of stock

  • 2α-Mannobiose is a disaccharide composed of two mannose molecules linked by a 1-2 glycosidic bond.{38349} It has been immobilized on monolithic capillary columns for the affinity purification of mannose binding proteins.{38350}  

     

    Brand:
    Cayman
    SKU:21848 -

    Out of stock

  • 2α-methyl Androsterone (Item No. 23087) is an analytical reference standard categorized as an anabolic androgenic steroid metabolite of mesterolone (Item No. 21171) and drostanolone (Item No. 21170).{41398} This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:23087 - 1 mg

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  • 2α-methyl Androsterone (Item No. 23087) is an analytical reference standard categorized as an anabolic androgenic steroid metabolite of mesterolone (Item No. 21171) and drostanolone (Item No. 21170).{41398} This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:23087 - 5 mg

    Available on backorder

  • 2α-methyl Androsterone (Item No. 23087) is an analytical reference standard categorized as an anabolic androgenic steroid metabolite of mesterolone (Item No. 21171) and drostanolone (Item No. 21170).{41398} This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:23087 - 500 µg

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  • 2α-methyl-5α-Androstan-17-one-3α-glucuronide (Item No. 23088) is an analytical reference standard categorized as an anabolic androgenic steroid metabolite.{48839} It is a metabolite of drostanolone (Item No. 21170). This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:23088 - 1 mg

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  • 2α-methyl-5α-Androstan-17-one-3α-glucuronide (Item No. 23088) is an analytical reference standard categorized as an anabolic androgenic steroid metabolite.{48839} It is a metabolite of drostanolone (Item No. 21170). This product is intended for research and forensic applications.  

     

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    Cayman
    SKU:23088 - 5 mg

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  • 3-(4-Chlorophenyl)-4-hydroxybutyric acid is an inactive metabolite of the GABAB receptor agonist baclofen (Item No. 18600).{45378,45379,45380}  

     

    Brand:
    Cayman
    SKU:21483 -

    Out of stock

  • 3-(4-Chlorophenyl)-4-hydroxybutyric acid is an inactive metabolite of the GABAB receptor agonist baclofen (Item No. 18600).{45378,45379,45380}  

     

    Brand:
    Cayman
    SKU:21483 -

    Out of stock

  • 3-(4-Chlorophenyl)-4-hydroxybutyric acid is an inactive metabolite of the GABAB receptor agonist baclofen (Item No. 18600).{45378,45379,45380}  

     

    Brand:
    Cayman
    SKU:21483 -

    Out of stock

  • Two Rho-associated kinases (ROCK), ROCK-I and ROCK-II, act downstream of the G protein Rho to regulate cytoskeletal stability. The ROCKs play important roles in diverse cellular functions including cell adhesion and proliferation, smooth muscle contraction, and stem cell renewal.{17734,17735,17322} 3-(4-Pyridyl)indole is a ROCK-I inhibitor (IC50 = 25 µM) that promotes cell spreading, inhibits membrane blebbing, and induces dissolution of actin stress fibers in a wound healing assay.{29128} It also inhibits ROCK-II and PRK2, another Rho-dependent kinase, with similar potency, while inhibiting MSK-1 and PKA with relatively weaker potency.{29128}  

     

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    Cayman
    SKU:-

    Available on backorder

  • Two Rho-associated kinases (ROCK), ROCK-I and ROCK-II, act downstream of the G protein Rho to regulate cytoskeletal stability. The ROCKs play important roles in diverse cellular functions including cell adhesion and proliferation, smooth muscle contraction, and stem cell renewal.{17734,17735,17322} 3-(4-Pyridyl)indole is a ROCK-I inhibitor (IC50 = 25 µM) that promotes cell spreading, inhibits membrane blebbing, and induces dissolution of actin stress fibers in a wound healing assay.{29128} It also inhibits ROCK-II and PRK2, another Rho-dependent kinase, with similar potency, while inhibiting MSK-1 and PKA with relatively weaker potency.{29128}  

     

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    Cayman
    SKU:-

    Available on backorder

  • Two Rho-associated kinases (ROCK), ROCK-I and ROCK-II, act downstream of the G protein Rho to regulate cytoskeletal stability. The ROCKs play important roles in diverse cellular functions including cell adhesion and proliferation, smooth muscle contraction, and stem cell renewal.{17734,17735,17322} 3-(4-Pyridyl)indole is a ROCK-I inhibitor (IC50 = 25 µM) that promotes cell spreading, inhibits membrane blebbing, and induces dissolution of actin stress fibers in a wound healing assay.{29128} It also inhibits ROCK-II and PRK2, another Rho-dependent kinase, with similar potency, while inhibiting MSK-1 and PKA with relatively weaker potency.{29128}  

     

    Brand:
    Cayman
    SKU:-

    Available on backorder

  • Two Rho-associated kinases (ROCK), ROCK-I and ROCK-II, act downstream of the G protein Rho to regulate cytoskeletal stability. The ROCKs play important roles in diverse cellular functions including cell adhesion and proliferation, smooth muscle contraction, and stem cell renewal.{17734,17735,17322} 3-(4-Pyridyl)indole is a ROCK-I inhibitor (IC50 = 25 µM) that promotes cell spreading, inhibits membrane blebbing, and induces dissolution of actin stress fibers in a wound healing assay.{29128} It also inhibits ROCK-II and PRK2, another Rho-dependent kinase, with similar potency, while inhibiting MSK-1 and PKA with relatively weaker potency.{29128}  

     

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    Cayman
    SKU:-

    Available on backorder

  • 3-(N-Maleimidopropionyl)-biocytin (MPB) is a versatile thiol-specific biotinylating reagent. It is specific for sulfhydryl groups or reduced disulfide bonds and will not label proteins lacking a free sulfhydryl group at a pH between 6.5 and 7.5. This probe can be used in combination with the appropriate avidin- or streptavidin-conjugated markers (i.e., fluorescent, enzyme-conjugated, etc.). MPB can be used to detect protein sulfhydryl groups on dot blots with sensitivities in the femtomole range.{14917} MPB can be utilized for cell sorting, enzyme immunoassay, protein blotting, and various cytochemical procedures.{14917}  

     

    Brand:
    Cayman
    SKU:10008879 - 1 mg

    Available on backorder

  • 3-(N-Maleimidopropionyl)-biocytin (MPB) is a versatile thiol-specific biotinylating reagent. It is specific for sulfhydryl groups or reduced disulfide bonds and will not label proteins lacking a free sulfhydryl group at a pH between 6.5 and 7.5. This probe can be used in combination with the appropriate avidin- or streptavidin-conjugated markers (i.e., fluorescent, enzyme-conjugated, etc.). MPB can be used to detect protein sulfhydryl groups on dot blots with sensitivities in the femtomole range.{14917} MPB can be utilized for cell sorting, enzyme immunoassay, protein blotting, and various cytochemical procedures.{14917}  

     

    Brand:
    Cayman
    SKU:10008879 - 10 mg

    Available on backorder

  • 3-(N-Maleimidopropionyl)-biocytin (MPB) is a versatile thiol-specific biotinylating reagent. It is specific for sulfhydryl groups or reduced disulfide bonds and will not label proteins lacking a free sulfhydryl group at a pH between 6.5 and 7.5. This probe can be used in combination with the appropriate avidin- or streptavidin-conjugated markers (i.e., fluorescent, enzyme-conjugated, etc.). MPB can be used to detect protein sulfhydryl groups on dot blots with sensitivities in the femtomole range.{14917} MPB can be utilized for cell sorting, enzyme immunoassay, protein blotting, and various cytochemical procedures.{14917}  

     

    Brand:
    Cayman
    SKU:10008879 - 5 mg

    Available on backorder

  • 3-(N-Maleimidopropionyl)-biocytin (MPB) is a versatile thiol-specific biotinylating reagent. It is specific for sulfhydryl groups or reduced disulfide bonds and will not label proteins lacking a free sulfhydryl group at a pH between 6.5 and 7.5. This probe can be used in combination with the appropriate avidin- or streptavidin-conjugated markers (i.e., fluorescent, enzyme-conjugated, etc.). MPB can be used to detect protein sulfhydryl groups on dot blots with sensitivities in the femtomole range.{14917} MPB can be utilized for cell sorting, enzyme immunoassay, protein blotting, and various cytochemical procedures.{14917}  

     

    Brand:
    Cayman
    SKU:10008879 - 50 mg

    Available on backorder

  • 3-[2-N-(Biotinyl)aminoethyldithio]propanoic acid features a biotin group and propanoic acid separated by a disulfide linkage. The carboxyl group of propanoic acid allows biotinylation of targets through either a chemical or enzymatic acylation reaction. The disulfide bond permits removal of the biotin group with reducing agents.  

     

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    Cayman
    SKU:-

    Out of stock

  • 3-[2-N-(Biotinyl)aminoethyldithio]propanoic acid features a biotin group and propanoic acid separated by a disulfide linkage. The carboxyl group of propanoic acid allows biotinylation of targets through either a chemical or enzymatic acylation reaction. The disulfide bond permits removal of the biotin group with reducing agents.  

     

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    Cayman
    SKU:-

    Out of stock

  • 3-[2-N-(Biotinyl)aminoethyldithio]propanoic acid features a biotin group and propanoic acid separated by a disulfide linkage. The carboxyl group of propanoic acid allows biotinylation of targets through either a chemical or enzymatic acylation reaction. The disulfide bond permits removal of the biotin group with reducing agents.  

     

    Brand:
    Cayman
    SKU:-

    Out of stock

  • 3-[2-N-(Biotinyl)aminoethyldithio]propanoic acid features a biotin group and propanoic acid separated by a disulfide linkage. The carboxyl group of propanoic acid allows biotinylation of targets through either a chemical or enzymatic acylation reaction. The disulfide bond permits removal of the biotin group with reducing agents.  

     

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    Cayman
    SKU:-

    Out of stock

  • 3-acetyl-11-keto-β-Boswellic acid is a naturally occurring pentacyclic triterpene isolated from the gum resin exudate from the stem of the tree B. serrata (frankincense).{30044} It selectively inhibits 5-lipoxygenase (IC50 = 1.5 µM) in an enzyme-directed, nonredox, and noncompetitive manner.{6066} 3-acetyl-11-keto-β-Boswellic acid and other members of the boswellic acid family have been studied for potential use in the control of inflammatory diseases, including arthritis and cancer.{30048,30047,30045,30046}  

     

    Brand:
    Cayman
    SKU:11672 - 1 mg

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  • 3-acetyl-11-keto-β-Boswellic acid is a naturally occurring pentacyclic triterpene isolated from the gum resin exudate from the stem of the tree B. serrata (frankincense).{30044} It selectively inhibits 5-lipoxygenase (IC50 = 1.5 µM) in an enzyme-directed, nonredox, and noncompetitive manner.{6066} 3-acetyl-11-keto-β-Boswellic acid and other members of the boswellic acid family have been studied for potential use in the control of inflammatory diseases, including arthritis and cancer.{30048,30047,30045,30046}  

     

    Brand:
    Cayman
    SKU:11672 - 10 mg

    Available on backorder

  • 3-acetyl-11-keto-β-Boswellic acid is a naturally occurring pentacyclic triterpene isolated from the gum resin exudate from the stem of the tree B. serrata (frankincense).{30044} It selectively inhibits 5-lipoxygenase (IC50 = 1.5 µM) in an enzyme-directed, nonredox, and noncompetitive manner.{6066} 3-acetyl-11-keto-β-Boswellic acid and other members of the boswellic acid family have been studied for potential use in the control of inflammatory diseases, including arthritis and cancer.{30048,30047,30045,30046}  

     

    Brand:
    Cayman
    SKU:11672 - 5 mg

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  • 3-Acetyldeoxy nivalenol is a mycotoxin that has been found in F. graminearum.{31920} In vivo, 3-acetyldeoxy nivalenol (40 mg/kg) induces duodenal and splenic cell necrosis, as well as lethality (LD50 = 70 mg/kg) in mice.{61111}  

     

    Brand:
    Cayman
    SKU:11429 - 1 mg

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  • 3-Acetyldeoxy nivalenol is a mycotoxin that has been found in F. graminearum.{31920} In vivo, 3-acetyldeoxy nivalenol (40 mg/kg) induces duodenal and splenic cell necrosis, as well as lethality (LD50 = 70 mg/kg) in mice.{61111}  

     

    Brand:
    Cayman
    SKU:11429 - 10 mg

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  • 3-Acetyldeoxy nivalenol is a mycotoxin that has been found in F. graminearum.{31920} In vivo, 3-acetyldeoxy nivalenol (40 mg/kg) induces duodenal and splenic cell necrosis, as well as lethality (LD50 = 70 mg/kg) in mice.{61111}  

     

    Brand:
    Cayman
    SKU:11429 - 5 mg

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  • 3-Acetyldeoxy nivalenol-13C17 is intended for use as an internal standard for the quantification of 3-acetyldeoxy nivalenol (Item No. 11429) by GC- or LC-MS. 3-Acetyldeoxy nivalenol is a mycotoxin that has been found in F. graminearum.{31920} In vivo, 3-acetyldeoxy nivalenol (40 mg/kg) induces duodenal and splenic cell necrosis, as well as lethality (LD50 = 70 mg/kg) in mice.{61111}  

     

    Brand:
    Cayman
    SKU:31258 - 1.2 ml

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  • 3-Acetylmorphine (3-MAM) is a less active metabolite of heroin (Item No. 9001543) compared to the more active 6-MAM (Item Nos. 19418 | 15880) and morphine (Item No. ISO60147).{25995,25996} 3-MAM has relatively weak affinity for µ-opioid receptors due to the placement of the acetyl group in the 3 position. This product is intended only for forensic and research purposes.  

     

    Brand:
    Cayman
    SKU:9001954 - 10 mg

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  • 3-Acetylmorphine (3-MAM) is a less active metabolite of heroin (Item No. 9001543) compared to the more active 6-MAM (Item Nos. 19418 | 15880) and morphine (Item No. ISO60147).{25995,25996} 3-MAM has relatively weak affinity for µ-opioid receptors due to the placement of the acetyl group in the 3 position. This product is intended only for forensic and research purposes.  

     

    Brand:
    Cayman
    SKU:9001954 - 5 mg

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  • 3-Acetylmorphine (3-MAM) is a less active metabolite of heroin (Item No. 9001543) compared to the more active 6-MAM (Item Nos. 19418 | 15880) and morphine (Item No. ISO60147).{25995,25996} 3-MAM has relatively weak affinity for µ-opioid receptors due to the placement of the acetyl group in the 3 position. This product is intended only for forensic and research purposes.  

     

    Brand:
    Cayman
    SKU:9001954 - 50 mg

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  • 3-Acetylpyridine NAD (APAD) is an analog of NAD+ (free acid) (nicotinamide adenine dinucleotide; Item No. 16077), a signaling molecule and cofactor or substrate for many enzymes.{20368,34523} APAD has been used to study the mechanisms of oxidative phosphorylation.{34522} It can be reduced by transdehydrogenase from NADH (sodium salt) (Item No. 16078).{34525} It can be reduced more efficiently and is more stable than NAD+; thus, it is useful as a substitute.{34524}  

     

    Brand:
    Cayman
    SKU:21884 -

    Out of stock

  • 3-Acetylpyridine NAD (APAD) is an analog of NAD+ (free acid) (nicotinamide adenine dinucleotide; Item No. 16077), a signaling molecule and cofactor or substrate for many enzymes.{20368,34523} APAD has been used to study the mechanisms of oxidative phosphorylation.{34522} It can be reduced by transdehydrogenase from NADH (sodium salt) (Item No. 16078).{34525} It can be reduced more efficiently and is more stable than NAD+; thus, it is useful as a substitute.{34524}  

     

    Brand:
    Cayman
    SKU:21884 -

    Out of stock

  • 3-Acetylpyridine NAD (APAD) is an analog of NAD+ (free acid) (nicotinamide adenine dinucleotide; Item No. 16077), a signaling molecule and cofactor or substrate for many enzymes.{20368,34523} APAD has been used to study the mechanisms of oxidative phosphorylation.{34522} It can be reduced by transdehydrogenase from NADH (sodium salt) (Item No. 16078).{34525} It can be reduced more efficiently and is more stable than NAD+; thus, it is useful as a substitute.{34524}  

     

    Brand:
    Cayman
    SKU:21884 -

    Out of stock

  • 3-Acetylpyridine NAD (APAD) is an analog of NAD+ (free acid) (nicotinamide adenine dinucleotide; Item No. 16077), a signaling molecule and cofactor or substrate for many enzymes.{20368,34523} APAD has been used to study the mechanisms of oxidative phosphorylation.{34522} It can be reduced by transdehydrogenase from NADH (sodium salt) (Item No. 16078).{34525} It can be reduced more efficiently and is more stable than NAD+; thus, it is useful as a substitute.{34524}  

     

    Brand:
    Cayman
    SKU:21884 -

    Out of stock

  • 3-Acetylursolic acid is a triterpene and derivative of ursolic acid (Item No. 10072) with diverse biological activities.{46903,46904,46905} It inhibits ADP-, thrombin-, or epinephrine-induced aggregation of isolated rat platelets (IC50s = P. falciparum in vitro (IC50 = 4 µM).{46904} It is also active against B. cereus, S. aureus, and S. pneumoniae (MICs = 39.1, 19.6, and 4.81 µM, respectively).{46905} It is cytotoxic to HepG2 cells (LC50 = 351 µM).  

     

    Brand:
    Cayman
    SKU:30220 - 10 mg

    Available on backorder

  • 3-Acetylursolic acid is a triterpene and derivative of ursolic acid (Item No. 10072) with diverse biological activities.{46903,46904,46905} It inhibits ADP-, thrombin-, or epinephrine-induced aggregation of isolated rat platelets (IC50s = P. falciparum in vitro (IC50 = 4 µM).{46904} It is also active against B. cereus, S. aureus, and S. pneumoniae (MICs = 39.1, 19.6, and 4.81 µM, respectively).{46905} It is cytotoxic to HepG2 cells (LC50 = 351 µM).  

     

    Brand:
    Cayman
    SKU:30220 - 25 mg

    Available on backorder

  • 3-Acetylursolic acid is a triterpene and derivative of ursolic acid (Item No. 10072) with diverse biological activities.{46903,46904,46905} It inhibits ADP-, thrombin-, or epinephrine-induced aggregation of isolated rat platelets (IC50s = P. falciparum in vitro (IC50 = 4 µM).{46904} It is also active against B. cereus, S. aureus, and S. pneumoniae (MICs = 39.1, 19.6, and 4.81 µM, respectively).{46905} It is cytotoxic to HepG2 cells (LC50 = 351 µM).  

     

    Brand:
    Cayman
    SKU:30220 - 5 mg

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  • 3-Acetylursolic acid is a triterpene and derivative of ursolic acid (Item No. 10072) with diverse biological activities.{46903,46904,46905} It inhibits ADP-, thrombin-, or epinephrine-induced aggregation of isolated rat platelets (IC50s = P. falciparum in vitro (IC50 = 4 µM).{46904} It is also active against B. cereus, S. aureus, and S. pneumoniae (MICs = 39.1, 19.6, and 4.81 µM, respectively).{46905} It is cytotoxic to HepG2 cells (LC50 = 351 µM).  

     

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    Cayman
    SKU:30220 - 50 mg

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  • The poly(ADP-ribose) polymerases (PARPs) comprise a family of enzymes which post-translationally modify proteins by poly(ADP-ribosyl)ation. Since some PARPs are activated by DNA strand breaks, PARP signaling has roles in DNA repair, apoptosis, inflammation, and other cellular responses. 3-amino Benzamide is an inhibitor of PARPs (Ki = 1.8 μM).{20002} Through its effects on PARPs, 3-amino benzamide causes telomere shortening and stimulates angiogenesis.{19998,19999} It has PARP-mediated actions in such diverse diseases as atherosclerosis, neurogenesis, and cancer.{20003,20000,18991}  

     

    Brand:
    Cayman
    SKU:10397 - 1 g

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  • The poly(ADP-ribose) polymerases (PARPs) comprise a family of enzymes which post-translationally modify proteins by poly(ADP-ribosyl)ation. Since some PARPs are activated by DNA strand breaks, PARP signaling has roles in DNA repair, apoptosis, inflammation, and other cellular responses. 3-amino Benzamide is an inhibitor of PARPs (Ki = 1.8 μM).{20002} Through its effects on PARPs, 3-amino benzamide causes telomere shortening and stimulates angiogenesis.{19998,19999} It has PARP-mediated actions in such diverse diseases as atherosclerosis, neurogenesis, and cancer.{20003,20000,18991}  

     

    Brand:
    Cayman
    SKU:10397 - 5 g

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  • 3-amino Benzamidoxime is a synthetic intermediate useful for pharmaceutical synthesis.  

     

    Brand:
    Cayman
    SKU:11074 - 1 g

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  • 3-amino Benzamidoxime is a synthetic intermediate useful for pharmaceutical synthesis.  

     

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    Cayman
    SKU:11074 - 5 g

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  • 3-amino Benzamidoxime is a synthetic intermediate useful for pharmaceutical synthesis.  

     

    Brand:
    Cayman
    SKU:11074 - 500 mg

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  • 3-amino Benzthioamide is a synthetic intermediate useful for pharmaceutical synthesis.  

     

    Brand:
    Cayman
    SKU:11064 - 1 g

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  • 3-amino Benzthioamide is a synthetic intermediate useful for pharmaceutical synthesis.  

     

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    Cayman
    SKU:11064 - 5 g

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  • 3-amino Benzthioamide is a synthetic intermediate useful for pharmaceutical synthesis.  

     

    Brand:
    Cayman
    SKU:11064 - 500 mg

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  • 3-Amino-2,6-piperidinedione is an active metabolite of (±)-thalidomide (Item No. 14610).{58145} In vivo, 3-amino-2,6-piperidinedione (400 mg/kg) increases hexobarbitone-induced sleeping time in rats.  

     

    Brand:
    Cayman
    SKU:31698 - 100 mg

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  • 3-Amino-2,6-piperidinedione is an active metabolite of (±)-thalidomide (Item No. 14610).{58145} In vivo, 3-amino-2,6-piperidinedione (400 mg/kg) increases hexobarbitone-induced sleeping time in rats.  

     

    Brand:
    Cayman
    SKU:31698 - 250 mg

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  • 3-Amino-2,6-piperidinedione is an active metabolite of (±)-thalidomide (Item No. 14610).{58145} In vivo, 3-amino-2,6-piperidinedione (400 mg/kg) increases hexobarbitone-induced sleeping time in rats.  

     

    Brand:
    Cayman
    SKU:31698 - 50 mg

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  • 3-Amino-2,6-piperidinedione is an active metabolite of (±)-thalidomide (Item No. 14610).{58145} In vivo, 3-amino-2,6-piperidinedione (400 mg/kg) increases hexobarbitone-induced sleeping time in rats.  

     

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    Cayman
    SKU:31698 - 500 mg

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  • 3-Aminopropylphosphonic acid (3-APPA) is a phosphonic analog of GABA that acts as a partial agonist of GABAB receptors (IC50 = 1.5 μM in a radioligand binding assay).{36477,23832} It induces relaxation in unstimulated isolated guinea pig ileum longitudinal muscle and reverses GABA- and baclofen-induced inhibition of twitch responses in isolated guinea pig ileum longitudinal muscle.{36477} 3-APPA (5 mg/kg) completely inhibits GABA- and baclofen-induced inhibition of vagally stimulated bronchospasms in guinea pigs.{36478} It also reverses the antitussive effect of baclofen in cats when administered at a dose of 3 mg/kg.{36479}  

     

    Brand:
    Cayman
    SKU:23556 - 100 mg

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  • 3-Aminopropylphosphonic acid (3-APPA) is a phosphonic analog of GABA that acts as a partial agonist of GABAB receptors (IC50 = 1.5 μM in a radioligand binding assay).{36477,23832} It induces relaxation in unstimulated isolated guinea pig ileum longitudinal muscle and reverses GABA- and baclofen-induced inhibition of twitch responses in isolated guinea pig ileum longitudinal muscle.{36477} 3-APPA (5 mg/kg) completely inhibits GABA- and baclofen-induced inhibition of vagally stimulated bronchospasms in guinea pigs.{36478} It also reverses the antitussive effect of baclofen in cats when administered at a dose of 3 mg/kg.{36479}  

     

    Brand:
    Cayman
    SKU:23556 - 250 mg

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  • 3-Aminopropylphosphonic acid (3-APPA) is a phosphonic analog of GABA that acts as a partial agonist of GABAB receptors (IC50 = 1.5 μM in a radioligand binding assay).{36477,23832} It induces relaxation in unstimulated isolated guinea pig ileum longitudinal muscle and reverses GABA- and baclofen-induced inhibition of twitch responses in isolated guinea pig ileum longitudinal muscle.{36477} 3-APPA (5 mg/kg) completely inhibits GABA- and baclofen-induced inhibition of vagally stimulated bronchospasms in guinea pigs.{36478} It also reverses the antitussive effect of baclofen in cats when administered at a dose of 3 mg/kg.{36479}  

     

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    Cayman
    SKU:23556 - 500 mg

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  • Ribonucleotide reductase, the rate-limiting enzyme for de novo DNA synthesis, is an excellent target for chemotherapy. Its increased activity in cancer cells is associated with malignant transformation and proliferation.{14245} 3-AP is a ribonucleotide reductase inhibitor and iron chelator with antitumor activity.{25052} At 5 μM it can enhance DU145, U251, and PSN1 tumor cell radiosensitivity in vitro, inhibiting DNA synthesis and repair.{25052} It destroys the tyrosine free radical in the R2/p53R2 subunits of ribonucleotide reductase by forming a redox active complex with iron, thus producing reactive oxygen species.{25051} Furthermore, 3-AP has been shown to activate an endoplasmic reticulum stress pathway, leading to the unfolded protein response and apoptosis.{25050}  

     

    Brand:
    Cayman
    SKU:-
  • Ribonucleotide reductase, the rate-limiting enzyme for de novo DNA synthesis, is an excellent target for chemotherapy. Its increased activity in cancer cells is associated with malignant transformation and proliferation.{14245} 3-AP is a ribonucleotide reductase inhibitor and iron chelator with antitumor activity.{25052} At 5 μM it can enhance DU145, U251, and PSN1 tumor cell radiosensitivity in vitro, inhibiting DNA synthesis and repair.{25052} It destroys the tyrosine free radical in the R2/p53R2 subunits of ribonucleotide reductase by forming a redox active complex with iron, thus producing reactive oxygen species.{25051} Furthermore, 3-AP has been shown to activate an endoplasmic reticulum stress pathway, leading to the unfolded protein response and apoptosis.{25050}  

     

    Brand:
    Cayman
    SKU:-
  • Ribonucleotide reductase, the rate-limiting enzyme for de novo DNA synthesis, is an excellent target for chemotherapy. Its increased activity in cancer cells is associated with malignant transformation and proliferation.{14245} 3-AP is a ribonucleotide reductase inhibitor and iron chelator with antitumor activity.{25052} At 5 μM it can enhance DU145, U251, and PSN1 tumor cell radiosensitivity in vitro, inhibiting DNA synthesis and repair.{25052} It destroys the tyrosine free radical in the R2/p53R2 subunits of ribonucleotide reductase by forming a redox active complex with iron, thus producing reactive oxygen species.{25051} Furthermore, 3-AP has been shown to activate an endoplasmic reticulum stress pathway, leading to the unfolded protein response and apoptosis.{25050}  

     

    Brand:
    Cayman
    SKU:-
  • Ribonucleotide reductase, the rate-limiting enzyme for de novo DNA synthesis, is an excellent target for chemotherapy. Its increased activity in cancer cells is associated with malignant transformation and proliferation.{14245} 3-AP is a ribonucleotide reductase inhibitor and iron chelator with antitumor activity.{25052} At 5 μM it can enhance DU145, U251, and PSN1 tumor cell radiosensitivity in vitro, inhibiting DNA synthesis and repair.{25052} It destroys the tyrosine free radical in the R2/p53R2 subunits of ribonucleotide reductase by forming a redox active complex with iron, thus producing reactive oxygen species.{25051} Furthermore, 3-AP has been shown to activate an endoplasmic reticulum stress pathway, leading to the unfolded protein response and apoptosis.{25050}  

     

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    Cayman
    SKU:-
  • 3-BODIPY-propanoylaminocaproic acid N-hydroxysuccinimide ester (BODIPY FL-X SE) is an amine-reactive fluorescent probe.{38447} BODIPY FL-X SE has been used to visualize proteins immobilized on PVDF membranes with minor excitation peaks at 300-360 nm, a primary excitation peak at 504 nm, and an emission maximum at 511 nm. It has also been used to increase the hydrophobicity and detectability of amino acids in transient trapping-micellar electrokinetic chromatography.{38448}  

     

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    Cayman
    SKU:20672 -

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  • 3-BODIPY-propanoylaminocaproic acid N-hydroxysuccinimide ester (BODIPY FL-X SE) is an amine-reactive fluorescent probe.{38447} BODIPY FL-X SE has been used to visualize proteins immobilized on PVDF membranes with minor excitation peaks at 300-360 nm, a primary excitation peak at 504 nm, and an emission maximum at 511 nm. It has also been used to increase the hydrophobicity and detectability of amino acids in transient trapping-micellar electrokinetic chromatography.{38448}  

     

    Brand:
    Cayman
    SKU:20672 -

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  • 3-BODIPY-propanoylaminocaproic acid N-hydroxysuccinimide ester (BODIPY FL-X SE) is an amine-reactive fluorescent probe.{38447} BODIPY FL-X SE has been used to visualize proteins immobilized on PVDF membranes with minor excitation peaks at 300-360 nm, a primary excitation peak at 504 nm, and an emission maximum at 511 nm. It has also been used to increase the hydrophobicity and detectability of amino acids in transient trapping-micellar electrokinetic chromatography.{38448}  

     

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    Cayman
    SKU:20672 -

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  • The aldo-keto reductase (AKR) enzymes constitute a family of related NADPH-dependent oxidoreductases. The 1C subfamily (AKR1C) includes four human hydroxysteroid dehydrogenases, with AKR1C1 being a 20α-HSD and the other three being 3α-HSDs. AKR1C1 metabolizes progesterone to an inactive progestin, 20α-hydroxy progesterone.{17634} In addition, AKR1C1 actions have been implicated in cancer and in the processing of neuroactive steroids involved in brain function.{17637,17636,17638,17635} 3-bromo-5-phenyl Salicylic acid selectively inhibits AKR1C1 (Ki = 4 nM) over AKR1C2 (Ki = 87 nM), AKR1C3 (Ki = 4.2 μM), and AKR1C4 (Ki = 18.2 μM).{17245} Moreover, it potently inhibits the metabolism of progesterone by bovine aortic endothelial cells overexpressing AKR1C1 (IC50 = 460 nM).{17245}  

     

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    Cayman
    SKU:-
  • The aldo-keto reductase (AKR) enzymes constitute a family of related NADPH-dependent oxidoreductases. The 1C subfamily (AKR1C) includes four human hydroxysteroid dehydrogenases, with AKR1C1 being a 20α-HSD and the other three being 3α-HSDs. AKR1C1 metabolizes progesterone to an inactive progestin, 20α-hydroxy progesterone.{17634} In addition, AKR1C1 actions have been implicated in cancer and in the processing of neuroactive steroids involved in brain function.{17637,17636,17638,17635} 3-bromo-5-phenyl Salicylic acid selectively inhibits AKR1C1 (Ki = 4 nM) over AKR1C2 (Ki = 87 nM), AKR1C3 (Ki = 4.2 μM), and AKR1C4 (Ki = 18.2 μM).{17245} Moreover, it potently inhibits the metabolism of progesterone by bovine aortic endothelial cells overexpressing AKR1C1 (IC50 = 460 nM).{17245}  

     

    Brand:
    Cayman
    SKU:-
  • The aldo-keto reductase (AKR) enzymes constitute a family of related NADPH-dependent oxidoreductases. The 1C subfamily (AKR1C) includes four human hydroxysteroid dehydrogenases, with AKR1C1 being a 20α-HSD and the other three being 3α-HSDs. AKR1C1 metabolizes progesterone to an inactive progestin, 20α-hydroxy progesterone.{17634} In addition, AKR1C1 actions have been implicated in cancer and in the processing of neuroactive steroids involved in brain function.{17637,17636,17638,17635} 3-bromo-5-phenyl Salicylic acid selectively inhibits AKR1C1 (Ki = 4 nM) over AKR1C2 (Ki = 87 nM), AKR1C3 (Ki = 4.2 μM), and AKR1C4 (Ki = 18.2 μM).{17245} Moreover, it potently inhibits the metabolism of progesterone by bovine aortic endothelial cells overexpressing AKR1C1 (IC50 = 460 nM).{17245}  

     

    Brand:
    Cayman
    SKU:-
  • The aldo-keto reductase (AKR) enzymes constitute a family of related NADPH-dependent oxidoreductases. The 1C subfamily (AKR1C) includes four human hydroxysteroid dehydrogenases, with AKR1C1 being a 20α-HSD and the other three being 3α-HSDs. AKR1C1 metabolizes progesterone to an inactive progestin, 20α-hydroxy progesterone.{17634} In addition, AKR1C1 actions have been implicated in cancer and in the processing of neuroactive steroids involved in brain function.{17637,17636,17638,17635} 3-bromo-5-phenyl Salicylic acid selectively inhibits AKR1C1 (Ki = 4 nM) over AKR1C2 (Ki = 87 nM), AKR1C3 (Ki = 4.2 μM), and AKR1C4 (Ki = 18.2 μM).{17245} Moreover, it potently inhibits the metabolism of progesterone by bovine aortic endothelial cells overexpressing AKR1C1 (IC50 = 460 nM).{17245}  

     

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    Cayman
    SKU:-
  • 3-Bromo-7-nitroindazole is a more potent inhibitor of nNOS than 7-nitroindazole in vitro, but unlike 7-nitroindazole, it is also potent against iNOS. The IC50 values for inhibition of rat nNOS, bovine eNOS, and rat iNOS are 0.17, 0.86, and 0.29 µM, respectively.{1339}  

     

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    Cayman
    SKU:81345 - 100 mg

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  • 3-Bromo-7-nitroindazole is a more potent inhibitor of nNOS than 7-nitroindazole in vitro, but unlike 7-nitroindazole, it is also potent against iNOS. The IC50 values for inhibition of rat nNOS, bovine eNOS, and rat iNOS are 0.17, 0.86, and 0.29 µM, respectively.{1339}  

     

    Brand:
    Cayman
    SKU:81345 - 25 mg

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  • 3-Bromo-7-nitroindazole is a more potent inhibitor of nNOS than 7-nitroindazole in vitro, but unlike 7-nitroindazole, it is also potent against iNOS. The IC50 values for inhibition of rat nNOS, bovine eNOS, and rat iNOS are 0.17, 0.86, and 0.29 µM, respectively.{1339}  

     

    Brand:
    Cayman
    SKU:81345 - 250 mg

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  • 3-Bromo-7-nitroindazole is a more potent inhibitor of nNOS than 7-nitroindazole in vitro, but unlike 7-nitroindazole, it is also potent against iNOS. The IC50 values for inhibition of rat nNOS, bovine eNOS, and rat iNOS are 0.17, 0.86, and 0.29 µM, respectively.{1339}  

     

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    Cayman
    SKU:81345 - 50 mg

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  • 4-Bromoamphetamine (4-BA) (Item No. 9001850) is a para-substituted amphetamine that acts as a monoamine releasing agent.{25537,25538} It is highly neurotoxic, producing long-term depletion of serotonin.{25537,25538} 3-BA is a structural isomer of 4-BA, having the bromine at the three rather than the four position. This product is intended only for forensic and research purposes.  

     

    Brand:
    Cayman
    SKU:9001849 - 1 mg

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  • 4-Bromoamphetamine (4-BA) (Item No. 9001850) is a para-substituted amphetamine that acts as a monoamine releasing agent.{25537,25538} It is highly neurotoxic, producing long-term depletion of serotonin.{25537,25538} 3-BA is a structural isomer of 4-BA, having the bromine at the three rather than the four position. This product is intended only for forensic and research purposes.  

     

    Brand:
    Cayman
    SKU:9001849 - 10 mg

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  • 4-Bromoamphetamine (4-BA) (Item No. 9001850) is a para-substituted amphetamine that acts as a monoamine releasing agent.{25537,25538} It is highly neurotoxic, producing long-term depletion of serotonin.{25537,25538} 3-BA is a structural isomer of 4-BA, having the bromine at the three rather than the four position. This product is intended only for forensic and research purposes.  

     

    Brand:
    Cayman
    SKU:9001849 - 5 mg

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  • 3-Bromomethcathinone is a designer drug which has been identified in products marketed as bath salts or plant food.{22047} The physiological properties of this compound are not known. This product is intended for forensic and research applications.  

     

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    Cayman
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  • 3-Bromomethcathinone is a designer drug which has been identified in products marketed as bath salts or plant food.{22047} The physiological properties of this compound are not known. This product is intended for forensic and research applications.  

     

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    Cayman
    SKU:-
  • 3-Bromomethcathinone is a designer drug which has been identified in products marketed as bath salts or plant food.{22047} The physiological properties of this compound are not known. This product is intended for forensic and research applications.  

     

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    Cayman
    SKU:-
  • 3-Bromopyruvic Acid (3-BP) is an alkylating agent and an antimetabolite of pyruvate that is metabolized through glutathione conjugation.{34038,34035} It decreases proliferation of hepatocellular carcinoma BEL-7402 cells that express hexokinase II, an isoform of hexokinase overexpressed in many cancers.{43142,34037} 3-BP reduces tumor growth and induces tumor necrosis in a hepatocellular carcinoma mouse xenograft model when administered at a dose of 50 mg/kg per day, six days per week, for three weeks.{43142}  

     

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    Cayman
    SKU:-

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  • 3-Bromopyruvic Acid (3-BP) is an alkylating agent and an antimetabolite of pyruvate that is metabolized through glutathione conjugation.{34038,34035} It decreases proliferation of hepatocellular carcinoma BEL-7402 cells that express hexokinase II, an isoform of hexokinase overexpressed in many cancers.{43142,34037} 3-BP reduces tumor growth and induces tumor necrosis in a hepatocellular carcinoma mouse xenograft model when administered at a dose of 50 mg/kg per day, six days per week, for three weeks.{43142}  

     

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    Cayman
    SKU:-

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  • 3-Bromotyrosine is a product of protein oxidation found after activation of eosinophils during an allergic response.{39006,39007,39009} It has been used as a marker of eosinophil peroxidase-induced protein oxidation in vitro and in vivo.{39007,39010} In addition to its production in eosinophils, 3-bromotyrosine is found at 5-fold higher levels in peritoneal exudate from mice infected with K. pneumoniae compared with uninfected animals, suggesting neutrophils release higher levels of oxidized products during inflammation.{39011} In a human study, 3-bromotyrosine was increased 10-fold in allergen-challenged lung samples from subjects with allergen-induced asthma.{39007}  

     

    Brand:
    Cayman
    SKU:22606 -

    Out of stock