Chemicals
Showing 4351–4500 of 41137 results
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2-hydroxy Myristic acid is a hydroxy fatty acid that has been found in bovine, human, and horse milk, cow and buffalo cheeses, sea bass filet, seal oil, human vernix caseosa, and wool wax.{41690} It inhibits cleavage between the enterovirus capsid proteins VP4 and VP2, a process required for enterovirus infectivity, as well as Junin and Tacaribe viral replication (IC50s = 20.1 and 14.2 μM, respectively).{46233,46234} 2-hydroxy Myristic acid was previously characterized as a weak inhibitor of peptide myristoylation (Ki = 200 μM) but has been shown to be inactive in ARL1 cells when used at 100 μM.{46235,43858} [Matreya, LLC. Catalog No. 1703]
Brand:CaymanSKU:90390 - 50 mgAvailable on backorder
2-hydroxy Myristic acid methyl ester is a rare hydroxylated fatty acid methyl ester that has been isolated from aquatic microbial sources.{38771} Levels of 2-hydroxy myristic acid methyl ester decrease to <1% in aquatic microbial communities after administration of the pesticide Atradex at a concentration of 245 mg/L.[Matreya, LLC. Catalog No. 1704]
Brand:CaymanSKU:24588 - 50 mgAvailable on backorder
2-hydroxy Palmitic acid is a form of the 16:0 long-chain saturated palmitic acid (Item No. 10006627).{39083} It is an intermediate in the metabolism of phytosphingosine to odd-numbered fatty acids.{39084} 2-hydroxy Palmitic acid levels in yeast fermentations increase following treatment with fumonisin B1 (Item No. 62580). [Matreya, LLC. Catalog No. 1705]
Brand:CaymanSKU:22679 -Out of stock
2-hydroxy Palmitic acid is a form of the 16:0 long-chain saturated palmitic acid (Item No. 10006627).{39083} It is an intermediate in the metabolism of phytosphingosine to odd-numbered fatty acids.{39084} 2-hydroxy Palmitic acid levels in yeast fermentations increase following treatment with fumonisin B1 (Item No. 62580). [Matreya, LLC. Catalog No. 1705]
Brand:CaymanSKU:22679 -Out of stock
2-hydroxy Palmitic acid is a form of the 16:0 long-chain saturated palmitic acid (Item No. 10006627).{39083} It is an intermediate in the metabolism of phytosphingosine to odd-numbered fatty acids.{39084} 2-hydroxy Palmitic acid levels in yeast fermentations increase following treatment with fumonisin B1 (Item No. 62580). [Matreya, LLC. Catalog No. 1705]
Brand:CaymanSKU:22679 -Out of stock
2-hydroxy Palmitic acid methyl ester is a naturally occuring hydroxy fatty acid methyl ester. It is a minor component in essential oils of P. sylvestris and B. javanica extracts which have larvicidal and cytotoxic activities, respectively.{39537,39538} [Matreya, LLC. Catalog No. 1706]
Brand:CaymanSKU:24589 - 50 mgAvailable on backorder
2-hydroxy Stearic acid is a naturally occurring hydroxylated fatty acid that has been found in humans and U. armoricana.{40839,40840,40841} It reduces growth of Ehrlich ascites tumor (EAT) cells in vitro when used at a concentration of 100 μM.{40842} Levels of 2-hydroxy stearic acid are elevated in human joint synovial fluid after ankle fracture and in patients with Buruli ulcer disease.{40840,40841} [Matreya, LLC. Catalog No. 1707]
Brand:CaymanSKU:24590 - 10 mgAvailable on backorder
2-hydroxy Stearic acid is a naturally occurring hydroxylated fatty acid that has been found in humans and U. armoricana.{40839,40840,40841} It reduces growth of Ehrlich ascites tumor (EAT) cells in vitro when used at a concentration of 100 μM.{40842} Levels of 2-hydroxy stearic acid are elevated in human joint synovial fluid after ankle fracture and in patients with Buruli ulcer disease.{40840,40841} [Matreya, LLC. Catalog No. 1707]
Brand:CaymanSKU:24590 - 25 mgAvailable on backorder
2-hydroxy Stearic acid is a naturally occurring hydroxylated fatty acid that has been found in humans and U. armoricana.{40839,40840,40841} It reduces growth of Ehrlich ascites tumor (EAT) cells in vitro when used at a concentration of 100 μM.{40842} Levels of 2-hydroxy stearic acid are elevated in human joint synovial fluid after ankle fracture and in patients with Buruli ulcer disease.{40840,40841} [Matreya, LLC. Catalog No. 1707]
Brand:CaymanSKU:24590 - 50 mgAvailable on backorder
2-hydroxy Stearic acid is a hydroxylated fatty acid methyl ester that broadens phase transition in dimyristoylphosphatidylcholine (DMPC) lipid membranes.{36607} It has been used in the synthesis of lipid-nucleotide conjugate anti-HIV agents to increase phosphodiester bond cleavage and the amount of liberated intracellular nucleotides.{36608} [Matreya, LLC. Catalog No. 1708]
Brand:CaymanSKU:24591 - 10 mgAvailable on backorder
2-hydroxy Stearic acid is a hydroxylated fatty acid methyl ester that broadens phase transition in dimyristoylphosphatidylcholine (DMPC) lipid membranes.{36607} It has been used in the synthesis of lipid-nucleotide conjugate anti-HIV agents to increase phosphodiester bond cleavage and the amount of liberated intracellular nucleotides.{36608} [Matreya, LLC. Catalog No. 1708]
Brand:CaymanSKU:24591 - 25 mgAvailable on backorder
2-hydroxy Stearic acid is a hydroxylated fatty acid methyl ester that broadens phase transition in dimyristoylphosphatidylcholine (DMPC) lipid membranes.{36607} It has been used in the synthesis of lipid-nucleotide conjugate anti-HIV agents to increase phosphodiester bond cleavage and the amount of liberated intracellular nucleotides.{36608} [Matreya, LLC. Catalog No. 1708]
Brand:CaymanSKU:24591 - 50 mgAvailable on backorder
2-hydroxy Tricosanoic acid is a hydroxylated fatty acid that has been found in the inner bark of E. globulus, the leaves of wild, kiyomi, and zweigeltrepe grape vines, C. elegans, and Pseudosuberites and S. massa sea sponges.{38892,38860,36609,36610} [Matreya, LLC. Catalog No. 1713]
Brand:CaymanSKU:24597 - 10 mgAvailable on backorder
2-hydroxy Tricosanoic acid methyl ester is a hydroxylated fatty acid methyl ester that has been found in ripe and unripe strawberry homogenates, Pseudosuberites and S. massa sea sponges, sediment samples from the Harney River, and the aerial parts of A. pilosa.{38859,38860,38856,41599} It inhibits protein tyrosine phosphatase 1B (PTP1B) and α-glucosidase with IC50 values of 36.39 and 112.8 μM, respectively.{41599} [Matreya, LLC. Catalog No. 1714]
Brand:CaymanSKU:24598 - 1 mgAvailable on backorder
2-hydroxy Tricosanoic acid methyl ester is a hydroxylated fatty acid methyl ester that has been found in ripe and unripe strawberry homogenates, Pseudosuberites and S. massa sea sponges, sediment samples from the Harney River, and the aerial parts of A. pilosa.{38859,38860,38856,41599} It inhibits protein tyrosine phosphatase 1B (PTP1B) and α-glucosidase with IC50 values of 36.39 and 112.8 μM, respectively.{41599} [Matreya, LLC. Catalog No. 1714]
Brand:CaymanSKU:24598 - 10 mgAvailable on backorder
2-hydroxy Tricosanoic acid methyl ester is a hydroxylated fatty acid methyl ester that has been found in ripe and unripe strawberry homogenates, Pseudosuberites and S. massa sea sponges, sediment samples from the Harney River, and the aerial parts of A. pilosa.{38859,38860,38856,41599} It inhibits protein tyrosine phosphatase 1B (PTP1B) and α-glucosidase with IC50 values of 36.39 and 112.8 μM, respectively.{41599} [Matreya, LLC. Catalog No. 1714]
Brand:CaymanSKU:24598 - 5 mgAvailable on backorder
2-Hydroxy-4-methoxybenzaldehyde is a phenol found in the root bark essential oil of P. sepium that has diverse biological activities, including antibacterial, antifungal, fungicidal, antioxidant, anti-virulence, and metal chelating properties.{55018,55019,55020} It is active against Gram-positive (MICs = 100-200 µg/ml) and Gram-negative bacteria (MICs = 125-200 µg/ml), as well as the fungus C. albicans and the phytopathogenic fungus M. oryzae (MICs = 150 and 300 µg/ml, respectively). 2-Hydroxy-4-methoxybenzaldehyde scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals in a cell-free assay (IC50 = 9.04 mg/ml) and acts as a metal chelator, inhibiting ferrozine-Fe2+ complex formation with an IC50 value of 2.31 mg/ml. It reduces the production of the virulence factor staphyloxanthin in clinical isolates of methicillin-resistant S. aureus (MRSA) when used at a concentration of 200 µg/ml and decreases the expression of the MRSA virulence regulatory genes saeS, geh, crtM, and sigB.{55019} 2-Hydroxy-4-methoxybenzaldehyde, when used in combination with the antibiotics amikacin (Item No. 15405), gentamicin, cefotaxime (Item No. 16040), vancomycin (Item No. 15327), or tetracycline (Item No. 14328), increases MRSA antibiotic sensitivity. It is also an intermediate in the synthesis of Schiff base-metal complexes with antiproliferative activity.{55020}
Brand:CaymanSKU:30091 - 100 mgAvailable on backorder
2-Hydroxy-4-methoxybenzaldehyde is a phenol found in the root bark essential oil of P. sepium that has diverse biological activities, including antibacterial, antifungal, fungicidal, antioxidant, anti-virulence, and metal chelating properties.{55018,55019,55020} It is active against Gram-positive (MICs = 100-200 µg/ml) and Gram-negative bacteria (MICs = 125-200 µg/ml), as well as the fungus C. albicans and the phytopathogenic fungus M. oryzae (MICs = 150 and 300 µg/ml, respectively). 2-Hydroxy-4-methoxybenzaldehyde scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals in a cell-free assay (IC50 = 9.04 mg/ml) and acts as a metal chelator, inhibiting ferrozine-Fe2+ complex formation with an IC50 value of 2.31 mg/ml. It reduces the production of the virulence factor staphyloxanthin in clinical isolates of methicillin-resistant S. aureus (MRSA) when used at a concentration of 200 µg/ml and decreases the expression of the MRSA virulence regulatory genes saeS, geh, crtM, and sigB.{55019} 2-Hydroxy-4-methoxybenzaldehyde, when used in combination with the antibiotics amikacin (Item No. 15405), gentamicin, cefotaxime (Item No. 16040), vancomycin (Item No. 15327), or tetracycline (Item No. 14328), increases MRSA antibiotic sensitivity. It is also an intermediate in the synthesis of Schiff base-metal complexes with antiproliferative activity.{55020}
Brand:CaymanSKU:30091 - 25 mgAvailable on backorder
2-Hydroxy-4-methoxybenzaldehyde is a phenol found in the root bark essential oil of P. sepium that has diverse biological activities, including antibacterial, antifungal, fungicidal, antioxidant, anti-virulence, and metal chelating properties.{55018,55019,55020} It is active against Gram-positive (MICs = 100-200 µg/ml) and Gram-negative bacteria (MICs = 125-200 µg/ml), as well as the fungus C. albicans and the phytopathogenic fungus M. oryzae (MICs = 150 and 300 µg/ml, respectively). 2-Hydroxy-4-methoxybenzaldehyde scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals in a cell-free assay (IC50 = 9.04 mg/ml) and acts as a metal chelator, inhibiting ferrozine-Fe2+ complex formation with an IC50 value of 2.31 mg/ml. It reduces the production of the virulence factor staphyloxanthin in clinical isolates of methicillin-resistant S. aureus (MRSA) when used at a concentration of 200 µg/ml and decreases the expression of the MRSA virulence regulatory genes saeS, geh, crtM, and sigB.{55019} 2-Hydroxy-4-methoxybenzaldehyde, when used in combination with the antibiotics amikacin (Item No. 15405), gentamicin, cefotaxime (Item No. 16040), vancomycin (Item No. 15327), or tetracycline (Item No. 14328), increases MRSA antibiotic sensitivity. It is also an intermediate in the synthesis of Schiff base-metal complexes with antiproliferative activity.{55020}
Brand:CaymanSKU:30091 - 50 mgAvailable on backorder
2-hydroxy-6-Methylbenzoic acid is a constituent of G. anandria, a well-known traditional Chinese medicinal herb, and also produced in various fungi, including P. patulum, where it is a precursor to the toxin patulin (Item No. 11346).{31004,31005} This polyketide is a key structural moiety for many different antibiotic and anticancer agents, including chlorothricin (Item No. 15501), maduropeptin, neocarzinostatin, and terreic acid.{31005,31003}
Brand:CaymanSKU:-Available on backorder
2-hydroxy-6-Methylbenzoic acid is a constituent of G. anandria, a well-known traditional Chinese medicinal herb, and also produced in various fungi, including P. patulum, where it is a precursor to the toxin patulin (Item No. 11346).{31004,31005} This polyketide is a key structural moiety for many different antibiotic and anticancer agents, including chlorothricin (Item No. 15501), maduropeptin, neocarzinostatin, and terreic acid.{31005,31003}
Brand:CaymanSKU:-Available on backorder
2-hydroxy-6-Methylbenzoic acid is a constituent of G. anandria, a well-known traditional Chinese medicinal herb, and also produced in various fungi, including P. patulum, where it is a precursor to the toxin patulin (Item No. 11346).{31004,31005} This polyketide is a key structural moiety for many different antibiotic and anticancer agents, including chlorothricin (Item No. 15501), maduropeptin, neocarzinostatin, and terreic acid.{31005,31003}
Brand:CaymanSKU:-Available on backorder
2-hydroxy Estradiol (2-HE2) is a cytochrome P450 metabolite of estradiol with low affinity for estrogen receptors. 2-HE is rapidly metabolized by catechol-O-methyltransferase (COMT) to form 2-methoxy estradiol (2-ME2) with a half-life of approximately ten minutes in rat.{16610} 2-ME2 has achieved considerable attention as an anti-cancer agent acting as an angiogenesis inhibitor via the HIF-1a pathway.{16608,16609,16611} Due to the rapid metabolism of 2-HE2, the effects attributed to 2-HE2, may actually be those of 2-ME2.{16610}
Brand:CaymanSKU:13019 - 1 mgAvailable on backorder
2-hydroxy Estradiol (2-HE2) is a cytochrome P450 metabolite of estradiol with low affinity for estrogen receptors. 2-HE is rapidly metabolized by catechol-O-methyltransferase (COMT) to form 2-methoxy estradiol (2-ME2) with a half-life of approximately ten minutes in rat.{16610} 2-ME2 has achieved considerable attention as an anti-cancer agent acting as an angiogenesis inhibitor via the HIF-1a pathway.{16608,16609,16611} Due to the rapid metabolism of 2-HE2, the effects attributed to 2-HE2, may actually be those of 2-ME2.{16610}
Brand:CaymanSKU:13019 - 10 mgAvailable on backorder
2-hydroxy Estradiol (2-HE2) is a cytochrome P450 metabolite of estradiol with low affinity for estrogen receptors. 2-HE is rapidly metabolized by catechol-O-methyltransferase (COMT) to form 2-methoxy estradiol (2-ME2) with a half-life of approximately ten minutes in rat.{16610} 2-ME2 has achieved considerable attention as an anti-cancer agent acting as an angiogenesis inhibitor via the HIF-1a pathway.{16608,16609,16611} Due to the rapid metabolism of 2-HE2, the effects attributed to 2-HE2, may actually be those of 2-ME2.{16610}
Brand:CaymanSKU:13019 - 25 mgAvailable on backorder
2-hydroxy Estradiol (2-HE2) is a cytochrome P450 metabolite of estradiol with low affinity for estrogen receptors. 2-HE is rapidly metabolized by catechol-O-methyltransferase (COMT) to form 2-methoxy estradiol (2-ME2) with a half-life of approximately ten minutes in rat.{16610} 2-ME2 has achieved considerable attention as an anti-cancer agent acting as an angiogenesis inhibitor via the HIF-1a pathway.{16608,16609,16611} Due to the rapid metabolism of 2-HE2, the effects attributed to 2-HE2, may actually be those of 2-ME2.{16610}
Brand:CaymanSKU:13019 - 5 mgAvailable on backorder
2-Hydroxypropyl-β-cyclodextrin (HP-β-CD) is a cyclic oligosaccharide containing seven D-(+)-glucopyranose units that is widely used to improve the aqueous solubility of various compounds, especially those containing a phenyl group.{26620,26621,23432} The circular arrangement of its glucose units produces a torus-shaped ring configuration in which the CH2 groups and ether linkages of the molecule face the hollow interior, resulting in a nonpolar, hydrophobic cavity and a polar, hydrophilic exterior. When combined in solution with other compounds, the nonpolar aromatic portions of that compound interact with the nonpolar interior of the HP-β-CD molecule, thus isolating the aromatic portion of the molecule from the water and thereby increasing its aqueous solubility.{26620,21228}
Brand:CaymanSKU:- 2-Hydroxypropyl-β-cyclodextrin (HP-β-CD) is a cyclic oligosaccharide containing seven D-(+)-glucopyranose units that is widely used to improve the aqueous solubility of various compounds, especially those containing a phenyl group.{26620,26621,23432} The circular arrangement of its glucose units produces a torus-shaped ring configuration in which the CH2 groups and ether linkages of the molecule face the hollow interior, resulting in a nonpolar, hydrophobic cavity and a polar, hydrophilic exterior. When combined in solution with other compounds, the nonpolar aromatic portions of that compound interact with the nonpolar interior of the HP-β-CD molecule, thus isolating the aromatic portion of the molecule from the water and thereby increasing its aqueous solubility.{26620,21228}
Brand:CaymanSKU:- 2-Hydroxypropyl-β-cyclodextrin (HP-β-CD) is a cyclic oligosaccharide containing seven D-(+)-glucopyranose units that is widely used to improve the aqueous solubility of various compounds, especially those containing a phenyl group.{26620,26621,23432} The circular arrangement of its glucose units produces a torus-shaped ring configuration in which the CH2 groups and ether linkages of the molecule face the hollow interior, resulting in a nonpolar, hydrophobic cavity and a polar, hydrophilic exterior. When combined in solution with other compounds, the nonpolar aromatic portions of that compound interact with the nonpolar interior of the HP-β-CD molecule, thus isolating the aromatic portion of the molecule from the water and thereby increasing its aqueous solubility.{26620,21228}
Brand:CaymanSKU:- 2-Hydroxypropyl-β-cyclodextrin (HP-β-CD) is a cyclic oligosaccharide containing seven D-(+)-glucopyranose units that is widely used to improve the aqueous solubility of various compounds, especially those containing a phenyl group.{26620,26621,23432} The circular arrangement of its glucose units produces a torus-shaped ring configuration in which the CH2 groups and ether linkages of the molecule face the hollow interior, resulting in a nonpolar, hydrophobic cavity and a polar, hydrophilic exterior. When combined in solution with other compounds, the nonpolar aromatic portions of that compound interact with the nonpolar interior of the HP-β-CD molecule, thus isolating the aromatic portion of the molecule from the water and thereby increasing its aqueous solubility.{26620,21228}
Brand:CaymanSKU:-
2-Imino-4-methylpiperidine is a potent, general NOS inhibitor. It exhibits IC50 values of 0.1, 1.1, and 0.2 µM for inhibition of human iNOS, eNOS, and nNOS, respectively, at an arginine concentration of 30 µM.{5579}
Brand:CaymanSKU:81015 - 10 mgAvailable on backorder
2-Imino-4-methylpiperidine is a potent, general NOS inhibitor. It exhibits IC50 values of 0.1, 1.1, and 0.2 µM for inhibition of human iNOS, eNOS, and nNOS, respectively, at an arginine concentration of 30 µM.{5579}
Brand:CaymanSKU:81015 - 25 mgAvailable on backorder
2-Imino-4-methylpiperidine is a potent, general NOS inhibitor. It exhibits IC50 values of 0.1, 1.1, and 0.2 µM for inhibition of human iNOS, eNOS, and nNOS, respectively, at an arginine concentration of 30 µM.{5579}
Brand:CaymanSKU:81015 - 5 mgAvailable on backorder
2-Imino-4-methylpiperidine is a potent, general NOS inhibitor. It exhibits IC50 values of 0.1, 1.1, and 0.2 µM for inhibition of human iNOS, eNOS, and nNOS, respectively, at an arginine concentration of 30 µM.{5579}
Brand:CaymanSKU:81015 - 50 mgAvailable on backorder
2-Iminobiotin is a cyclic guanidino analog of biotin that acts as a reversible inhibitor of inducible nitric oxide synthase (iNOS) and neuronal NOS (nNOS; Kis = 21.8 and 37.5 µM for mouse iNOS and rat nNOS, respectively).{32524} It also provides sex-specific neuroprotection against hypoxia-ischemia in neonatal rats by an NO-independent mechanism.{32522} 2-Iminobiotin has also been used to capture membrane-bound proteins through biotin-avidin interactions.{32523}
Brand:CaymanSKU:20812 -Available on backorder
2-Iminobiotin is a cyclic guanidino analog of biotin that acts as a reversible inhibitor of inducible nitric oxide synthase (iNOS) and neuronal NOS (nNOS; Kis = 21.8 and 37.5 µM for mouse iNOS and rat nNOS, respectively).{32524} It also provides sex-specific neuroprotection against hypoxia-ischemia in neonatal rats by an NO-independent mechanism.{32522} 2-Iminobiotin has also been used to capture membrane-bound proteins through biotin-avidin interactions.{32523}
Brand:CaymanSKU:20812 -Available on backorder
2-Iminobiotin is a cyclic guanidino analog of biotin that acts as a reversible inhibitor of inducible nitric oxide synthase (iNOS) and neuronal NOS (nNOS; Kis = 21.8 and 37.5 µM for mouse iNOS and rat nNOS, respectively).{32524} It also provides sex-specific neuroprotection against hypoxia-ischemia in neonatal rats by an NO-independent mechanism.{32522} 2-Iminobiotin has also been used to capture membrane-bound proteins through biotin-avidin interactions.{32523}
Brand:CaymanSKU:20812 -Available on backorder
Some halogenated amphetamines deplete brain serotonin levels and display pronounced neurotoxicity.{25537} 2-Iodoamphetamine is a halogenated amphetamine featuring an iodine atom at the ortho position of the phenyl group. The physiological and toxicological properties of this compound are not known. This product is intended for forensic and research applications.
Brand:CaymanSKU:9001851 - 1 mgAvailable on backorder
Some halogenated amphetamines deplete brain serotonin levels and display pronounced neurotoxicity.{25537} 2-Iodoamphetamine is a halogenated amphetamine featuring an iodine atom at the ortho position of the phenyl group. The physiological and toxicological properties of this compound are not known. This product is intended for forensic and research applications.
Brand:CaymanSKU:9001851 - 10 mgAvailable on backorder
Some halogenated amphetamines deplete brain serotonin levels and display pronounced neurotoxicity.{25537} 2-Iodoamphetamine is a halogenated amphetamine featuring an iodine atom at the ortho position of the phenyl group. The physiological and toxicological properties of this compound are not known. This product is intended for forensic and research applications.
Brand:CaymanSKU:9001851 - 5 mgAvailable on backorder
2-iodomelatonin is a potent agonist of melatonin receptor 1 (MT1; Ki = 28 pM) that is 5-fold selective for MT1 over MT2.{26017,26021} It inhibits forskolin-stimulated cAMP production in CHO cells expressing human MT1 30-fold more potently than melatonin (Item No. 14427) with an EC50 value of 11 pM. 2-iodomelatonin has been used to characterize the role of MT1 in melatonin-mediated signaling.{40764,40765}
Brand:CaymanSKU:19711 -Available on backorder
2-iodomelatonin is a potent agonist of melatonin receptor 1 (MT1; Ki = 28 pM) that is 5-fold selective for MT1 over MT2.{26017,26021} It inhibits forskolin-stimulated cAMP production in CHO cells expressing human MT1 30-fold more potently than melatonin (Item No. 14427) with an EC50 value of 11 pM. 2-iodomelatonin has been used to characterize the role of MT1 in melatonin-mediated signaling.{40764,40765}
Brand:CaymanSKU:19711 -Available on backorder
2-iodomelatonin is a potent agonist of melatonin receptor 1 (MT1; Ki = 28 pM) that is 5-fold selective for MT1 over MT2.{26017,26021} It inhibits forskolin-stimulated cAMP production in CHO cells expressing human MT1 30-fold more potently than melatonin (Item No. 14427) with an EC50 value of 11 pM. 2-iodomelatonin has been used to characterize the role of MT1 in melatonin-mediated signaling.{40764,40765}
Brand:CaymanSKU:19711 -Available on backorder
2-keto-D-Glucose has been used as a building block in the synthesis of carbohydrates.{42035} It is an intermediate in the conversion of D-glucose (Item No. 23733) into D-fructose that was originally isolated from a variety of fungi, algae, and shellfish.{42036} It has slow-onset, long-lasting antioxidant properties in an electron paramagnetic resonance (EPR) assay.{42037} 2-keto-D-Glucose has also been found as a glucose degradation product in heat-sterilized peritoneal dialysis fluids.{42038}
Brand:CaymanSKU:20908 -Out of stock
2-keto-D-Glucose has been used as a building block in the synthesis of carbohydrates.{42035} It is an intermediate in the conversion of D-glucose (Item No. 23733) into D-fructose that was originally isolated from a variety of fungi, algae, and shellfish.{42036} It has slow-onset, long-lasting antioxidant properties in an electron paramagnetic resonance (EPR) assay.{42037} 2-keto-D-Glucose has also been found as a glucose degradation product in heat-sterilized peritoneal dialysis fluids.{42038}
Brand:CaymanSKU:20908 -Out of stock
2-keto-D-Glucose has been used as a building block in the synthesis of carbohydrates.{42035} It is an intermediate in the conversion of D-glucose (Item No. 23733) into D-fructose that was originally isolated from a variety of fungi, algae, and shellfish.{42036} It has slow-onset, long-lasting antioxidant properties in an electron paramagnetic resonance (EPR) assay.{42037} 2-keto-D-Glucose has also been found as a glucose degradation product in heat-sterilized peritoneal dialysis fluids.{42038}
Brand:CaymanSKU:20908 -Out of stock
2-keto-D-Glucose has been used as a building block in the synthesis of carbohydrates.{42035} It is an intermediate in the conversion of D-glucose (Item No. 23733) into D-fructose that was originally isolated from a variety of fungi, algae, and shellfish.{42036} It has slow-onset, long-lasting antioxidant properties in an electron paramagnetic resonance (EPR) assay.{42037} 2-keto-D-Glucose has also been found as a glucose degradation product in heat-sterilized peritoneal dialysis fluids.{42038}
Brand:CaymanSKU:20908 -Out of stock
2-Arachidonoyl glycerol (2-AG) has been isolated from porcine brain, and has been characterized as the natural endocannabinoid ligand for the CB1 receptor.{4614,5306} The congener of 2-AG in which a linoleoyl group replaces the arachidonoyl group is 2-linoleoyl glycerol (2-LG), and this compound also appears in vivo in conjunction with 2-AG.{9610} Although the intrinsic activity of 2-LG is low, it potentiates the activity of other endocannabinoids, including 2-AG. This “entourage” effect has been attributed to blockade of the breakdown and reuptake pathways that normally function to reduce endocannabinoid levels rapidly upon release.
Brand:CaymanSKU:62260 - 1 mgAvailable on backorder
2-Arachidonoyl glycerol (2-AG) has been isolated from porcine brain, and has been characterized as the natural endocannabinoid ligand for the CB1 receptor.{4614,5306} The congener of 2-AG in which a linoleoyl group replaces the arachidonoyl group is 2-linoleoyl glycerol (2-LG), and this compound also appears in vivo in conjunction with 2-AG.{9610} Although the intrinsic activity of 2-LG is low, it potentiates the activity of other endocannabinoids, including 2-AG. This “entourage” effect has been attributed to blockade of the breakdown and reuptake pathways that normally function to reduce endocannabinoid levels rapidly upon release.
Brand:CaymanSKU:62260 - 10 mgAvailable on backorder
2-Arachidonoyl glycerol (2-AG) has been isolated from porcine brain, and has been characterized as the natural endocannabinoid ligand for the CB1 receptor.{4614,5306} The congener of 2-AG in which a linoleoyl group replaces the arachidonoyl group is 2-linoleoyl glycerol (2-LG), and this compound also appears in vivo in conjunction with 2-AG.{9610} Although the intrinsic activity of 2-LG is low, it potentiates the activity of other endocannabinoids, including 2-AG. This “entourage” effect has been attributed to blockade of the breakdown and reuptake pathways that normally function to reduce endocannabinoid levels rapidly upon release.
Brand:CaymanSKU:62260 - 5 mgAvailable on backorder
2-Arachidonoyl glycerol (2-AG) has been isolated from porcine brain, and has been characterized as the natural endocannabinoid ligand for the CB1 receptor.{4614,5306} The congener of 2-AG in which a linoleoyl group replaces the arachidonoyl group is 2-linoleoyl glycerol (2-LG), and this compound also appears in vivo in conjunction with 2-AG.{9610} Although the intrinsic activity of 2-LG is low, it potentiates the activity of other endocannabinoids, including 2-AG. This “entourage” effect has been attributed to blockade of the breakdown and reuptake pathways that normally function to reduce endocannabinoid levels rapidly upon release.
Brand:CaymanSKU:62260 - 500 µgAvailable on backorder
2-MAPB is an analog of (aminopropyl)benzofurans, which include 6-APB (Item No. 11079), also known as benzo fury. The physiological and toxicological properties of this compound are not known. This product is intended for forensic and research applications.
Brand:CaymanSKU:-Out of stock
2-MAPB is an analog of (aminopropyl)benzofurans, which include 6-APB (Item No. 11079), also known as benzo fury. The physiological and toxicological properties of this compound are not known. This product is intended for forensic and research applications.
Brand:CaymanSKU:-Out of stock
2-MAPB is an analog of (aminopropyl)benzofurans, which include 6-APB (Item No. 11079), also known as benzo fury. The physiological and toxicological properties of this compound are not known. This product is intended for forensic and research applications.
Brand:CaymanSKU:-Out of stock
Ketamine (Item No. 11630) is a dissociative anesthetic that acts as an NMDA receptor channel blocker.{25284} It is regulated as a Schedule III compound in the United States. 2-methoxy Ketamine is an analog of ketamine in which the 2-chloro group is replaced with a methoxy group. The physiological and toxicological properties of this compound are unknown. This product is intended for forensic and research applications.
Brand:CaymanSKU:12048 - 1 mgAvailable on backorder
Ketamine (Item No. 11630) is a dissociative anesthetic that acts as an NMDA receptor channel blocker.{25284} It is regulated as a Schedule III compound in the United States. 2-methoxy Ketamine is an analog of ketamine in which the 2-chloro group is replaced with a methoxy group. The physiological and toxicological properties of this compound are unknown. This product is intended for forensic and research applications.
Brand:CaymanSKU:12048 - 10 mgAvailable on backorder
Ketamine (Item No. 11630) is a dissociative anesthetic that acts as an NMDA receptor channel blocker.{25284} It is regulated as a Schedule III compound in the United States. 2-methoxy Ketamine is an analog of ketamine in which the 2-chloro group is replaced with a methoxy group. The physiological and toxicological properties of this compound are unknown. This product is intended for forensic and research applications.
Brand:CaymanSKU:12048 - 5 mgAvailable on backorder
2-Methoxyamphetamine is an amphetamine featuring a methoxy group in the 2, or ortho, position of the phenyl group. It is much weaker than either para- or meta-methoxyamphetamines at altering serotonin release or reuptake in rat brain tissues.{25667} This product is intended for forensic and research applications.
Brand:CaymanSKU:9001915 - 10 mgAvailable on backorder
2-Methoxyamphetamine is an amphetamine featuring a methoxy group in the 2, or ortho, position of the phenyl group. It is much weaker than either para- or meta-methoxyamphetamines at altering serotonin release or reuptake in rat brain tissues.{25667} This product is intended for forensic and research applications.
Brand:CaymanSKU:9001915 - 5 mgAvailable on backorder
2-Methoxyamphetamine is an amphetamine featuring a methoxy group in the 2, or ortho, position of the phenyl group. It is much weaker than either para- or meta-methoxyamphetamines at altering serotonin release or reuptake in rat brain tissues.{25667} This product is intended for forensic and research applications.
Brand:CaymanSKU:9001915 - 50 mgAvailable on backorder
2-methoxy Estradiol (2-ME2) is a natural metabolite formed by CYP450-mediated hydroxylation followed by catechol-O-methyltransferase (COMT) methylation of estradiol. Administration of 2-hydroxy estradiol (2-HE2) to rats results in formation and clearance of 2-ME2 with t½ values of 7.9 and 24.9 minutes, respectively.{16610} 2-ME2 exhibits no affinity for estrogen receptors. 2-ME2 has achieved considerable attention as an anti-cancer agent acting as an angiogenesis inhibitor via the HIF-1α pathway.{16608,16609,16611} The levels of COMT and 2-ME2 are significantly lower in women with severe pre-eclampsia.{16513}
Brand:CaymanSKU:13021 - 10 mgAvailable on backorder
2-methoxy Estradiol (2-ME2) is a natural metabolite formed by CYP450-mediated hydroxylation followed by catechol-O-methyltransferase (COMT) methylation of estradiol. Administration of 2-hydroxy estradiol (2-HE2) to rats results in formation and clearance of 2-ME2 with t½ values of 7.9 and 24.9 minutes, respectively.{16610} 2-ME2 exhibits no affinity for estrogen receptors. 2-ME2 has achieved considerable attention as an anti-cancer agent acting as an angiogenesis inhibitor via the HIF-1α pathway.{16608,16609,16611} The levels of COMT and 2-ME2 are significantly lower in women with severe pre-eclampsia.{16513}
Brand:CaymanSKU:13021 - 25 mgAvailable on backorder
2-methoxy Estradiol (2-ME2) is a natural metabolite formed by CYP450-mediated hydroxylation followed by catechol-O-methyltransferase (COMT) methylation of estradiol. Administration of 2-hydroxy estradiol (2-HE2) to rats results in formation and clearance of 2-ME2 with t½ values of 7.9 and 24.9 minutes, respectively.{16610} 2-ME2 exhibits no affinity for estrogen receptors. 2-ME2 has achieved considerable attention as an anti-cancer agent acting as an angiogenesis inhibitor via the HIF-1α pathway.{16608,16609,16611} The levels of COMT and 2-ME2 are significantly lower in women with severe pre-eclampsia.{16513}
Brand:CaymanSKU:13021 - 5 mgAvailable on backorder
2-methoxy Estradiol (2-ME2) is a natural metabolite formed by CYP450-mediated hydroxylation followed by catechol-O-methyltransferase (COMT) methylation of estradiol. Administration of 2-hydroxy estradiol (2-HE2) to rats results in formation and clearance of 2-ME2 with t½ values of 7.9 and 24.9 minutes, respectively.{16610} 2-ME2 exhibits no affinity for estrogen receptors. 2-ME2 has achieved considerable attention as an anti-cancer agent acting as an angiogenesis inhibitor via the HIF-1α pathway.{16608,16609,16611} The levels of COMT and 2-ME2 are significantly lower in women with severe pre-eclampsia.{16513}
Brand:CaymanSKU:13021 - 50 mgAvailable on backorder
2-methyl AP-237 (hydrochloride) (Item No. 26485) is an analytical reference standard categorized as an analgesic.{46106} This product is intended for research and forensic applications.
Brand:CaymanSKU:26485 - 1 mgAvailable on backorder
2-methyl AP-237 (hydrochloride) (Item No. 26485) is an analytical reference standard categorized as an analgesic.{46106} This product is intended for research and forensic applications.
Brand:CaymanSKU:26485 - 5 mgAvailable on backorder
2-methyl Benzamideoxime is a synthetic intermediate or building block for drug discovery or pharmaceutical synthesis.
Brand:CaymanSKU:13002 - 1 gAvailable on backorder
2-methyl Benzamideoxime is a synthetic intermediate or building block for drug discovery or pharmaceutical synthesis.
Brand:CaymanSKU:13002 - 5 gAvailable on backorder
2-methyl Benzamideoxime is a synthetic intermediate or building block for drug discovery or pharmaceutical synthesis.
Brand:CaymanSKU:13002 - 500 mgAvailable on backorder
2-methyl DMT (Item No. 29347) is an analytical reference standard categorized as a tryptamine. This product is intended for research and forensic applications.
Brand:CaymanSKU:29347 - 1 mgAvailable on backorder
2-methyl DMT (Item No. 29347) is an analytical reference standard categorized as a tryptamine. This product is intended for research and forensic applications.
Brand:CaymanSKU:29347 - 5 mgAvailable on backorder
Brand:CaymanSKU:10007138 - 1 gAvailable on backorder
Brand:CaymanSKU:10007138 - 10 gAvailable on backorder
Brand:CaymanSKU:10007138 - 5 gAvailable on backorder
Brand:CaymanSKU:10007138 - 50 gAvailable on backorder
2-methyl-3-Pyrimidin-2-yl-propionic acid is a synthetic intermediate useful for pharmaceutical synthesis.
Brand:CaymanSKU:10007118 - 1 gAvailable on backorder
2-methyl-3-Pyrimidin-2-yl-propionic acid is a synthetic intermediate useful for pharmaceutical synthesis.
Brand:CaymanSKU:10007118 - 100 mgAvailable on backorder
2-methyl-3-Pyrimidin-2-yl-propionic acid is a synthetic intermediate useful for pharmaceutical synthesis.
Brand:CaymanSKU:10007118 - 50 mgAvailable on backorder
2-methyl-3-Pyrimidin-2-yl-propionic acid is a synthetic intermediate useful for pharmaceutical synthesis.
Brand:CaymanSKU:10007118 - 500 mgAvailable on backorder
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