Chemicals
Showing 3451–3600 of 41137 results
-
13Z,16Z-Docosadienoic acid is a natural ω-6 polyunsaturated fatty acid (PUFA). It is an agonist of free fatty acid receptor 4 (FFAR4, also known as GPR120) and strongly inhibits the secretion of ghrelin by isolated mouse gastric cells.{32737} This 20:2 PUFA has been identified in mammals, fish, plants, and anaerobic fungi.{32733,32734,32735,32736,32738}
Brand:CaymanSKU:20749 -Available on backorder
13Z,16Z-Docosadienoic acid is a natural ω-6 polyunsaturated fatty acid (PUFA). It is an agonist of free fatty acid receptor 4 (FFAR4, also known as GPR120) and strongly inhibits the secretion of ghrelin by isolated mouse gastric cells.{32737} This 20:2 PUFA has been identified in mammals, fish, plants, and anaerobic fungi.{32733,32734,32735,32736,32738}
Brand:CaymanSKU:20749 -Available on backorder
13Z,16Z-Docosadienoic acid is a natural ω-6 polyunsaturated fatty acid (PUFA). It is an agonist of free fatty acid receptor 4 (FFAR4, also known as GPR120) and strongly inhibits the secretion of ghrelin by isolated mouse gastric cells.{32737} This 20:2 PUFA has been identified in mammals, fish, plants, and anaerobic fungi.{32733,32734,32735,32736,32738}
Brand:CaymanSKU:20749 -Available on backorder
14-Anhydrodigitoxigenin is a cardenolide and a derivative of digitoxin.{48892} It reduces the activity of guinea pig heart Na+/K+-ATPase by 15% when used at a concentration of 10 µM.{48893}
Brand:CaymanSKU:30439 - 10 mgAvailable on backorder
14-Anhydrodigitoxigenin is a cardenolide and a derivative of digitoxin.{48892} It reduces the activity of guinea pig heart Na+/K+-ATPase by 15% when used at a concentration of 10 µM.{48893}
Brand:CaymanSKU:30439 - 25 mgAvailable on backorder
14-Anhydrodigitoxigenin is a cardenolide and a derivative of digitoxin.{48892} It reduces the activity of guinea pig heart Na+/K+-ATPase by 15% when used at a concentration of 10 µM.{48893}
Brand:CaymanSKU:30439 - 5 mgAvailable on backorder
14-Anhydrodigitoxigenin is a cardenolide and a derivative of digitoxin.{48892} It reduces the activity of guinea pig heart Na+/K+-ATPase by 15% when used at a concentration of 10 µM.{48893}
Brand:CaymanSKU:30439 - 50 mgAvailable on backorder
14-dehydro Zymostenol is a precursor to cholesterol (Item No. 9003100).{52493} It increases the percentage of myelin basic protein-positive (MBP+) oligodendrocytes formed from oligodendrocyte precursor cells when used at concentrations of 5.8 and 17 µM.{48202}
Brand:CaymanSKU:29534 - 1 mgAvailable on backorder
14-dehydro Zymostenol is a precursor to cholesterol (Item No. 9003100).{52493} It increases the percentage of myelin basic protein-positive (MBP+) oligodendrocytes formed from oligodendrocyte precursor cells when used at concentrations of 5.8 and 17 µM.{48202}
Brand:CaymanSKU:29534 - 5 mgAvailable on backorder
14-dehydro Zymostenol is a precursor to cholesterol (Item No. 9003100).{52493} It increases the percentage of myelin basic protein-positive (MBP+) oligodendrocytes formed from oligodendrocyte precursor cells when used at concentrations of 5.8 and 17 µM.{48202}
Brand:CaymanSKU:29534 - 500 µgAvailable on backorder
14-deoxy-11,12-didehydro Andrographolide is an analog of the natural diterpenoid andrographolide (Item No. 11679) that can be isolated from A. paniculata.{28452} It retains the anti-inflammatory, antiallergenic, immuno-stimulatory, antiviral, antioxidant, hepatoprotective, and cardiovascular activities of andrographolide without producing cytotoxicity in KB cells (ED50 >20 µg/ml) that can occur with andrographolide 6.5 µg/ml.{28452,21112}
Brand:CaymanSKU:11670 - 1 mgAvailable on backorder
14-deoxy-11,12-didehydro Andrographolide is an analog of the natural diterpenoid andrographolide (Item No. 11679) that can be isolated from A. paniculata.{28452} It retains the anti-inflammatory, antiallergenic, immuno-stimulatory, antiviral, antioxidant, hepatoprotective, and cardiovascular activities of andrographolide without producing cytotoxicity in KB cells (ED50 >20 µg/ml) that can occur with andrographolide 6.5 µg/ml.{28452,21112}
Brand:CaymanSKU:11670 - 10 mgAvailable on backorder
14-deoxy-11,12-didehydro Andrographolide is an analog of the natural diterpenoid andrographolide (Item No. 11679) that can be isolated from A. paniculata.{28452} It retains the anti-inflammatory, antiallergenic, immuno-stimulatory, antiviral, antioxidant, hepatoprotective, and cardiovascular activities of andrographolide without producing cytotoxicity in KB cells (ED50 >20 µg/ml) that can occur with andrographolide 6.5 µg/ml.{28452,21112}
Brand:CaymanSKU:11670 - 5 mgAvailable on backorder
14-deoxy-11,12-didehydro Andrographolide is an analog of the natural diterpenoid andrographolide (Item No. 11679) that can be isolated from A. paniculata.{28452} It retains the anti-inflammatory, antiallergenic, immuno-stimulatory, antiviral, antioxidant, hepatoprotective, and cardiovascular activities of andrographolide without producing cytotoxicity in KB cells (ED50 >20 µg/ml) that can occur with andrographolide 6.5 µg/ml.{28452,21112}
Brand:CaymanSKU:11670 - 500 µgAvailable on backorder
14-Deoxyandrographolide is a diterpene lactone that has been found in A. paniculata and has diverse biological activities, including anticancer, hepatoprotective, antioxidative, and antidiabetic properties.{58034},{58035},{58036},{58037} It inhibits the growth of HL-60 cells with a GI50 value of 25.46 µM and is cytotoxic to T47D cells (EC50 = 2.8 µg/ml) but not HepG2 or NCI H23 cells (EC50s = 28.3 and 26.4 µg/ml, respectively).{58034},{58035} 14-Deoxyandrographolide (10 and 25 µM) increases AMPK phosphorylation and glucose uptake in L6 myotubes and potentiates the effect of insulin to increase cell surface levels of GLUT4 in L6-GLUT4myc cells.{58037} It reduces blood glucose levels in rats in a model of streptozotocin-induced diabetes and in db/db diabetic mice when administered at a dose of 100 mg/kg. 14-Deoxyandrographolide reduces ethanol-induced hepatotoxicity in rats when administered at a dose of 15 mg/kg per day for the last four weeks of an eight-week ethanol exposure period.{58036} It also reduces protein carbonyl and thiobarbituric acid reactive substances (TBARS) levels and increases total glutathione (GSH) levels in isolated rat hepatocytes in the same model.
Brand:CaymanSKU:31140 - 1 mgAvailable on backorder
14-Deoxyandrographolide is a diterpene lactone that has been found in A. paniculata and has diverse biological activities, including anticancer, hepatoprotective, antioxidative, and antidiabetic properties.{58034},{58035},{58036},{58037} It inhibits the growth of HL-60 cells with a GI50 value of 25.46 µM and is cytotoxic to T47D cells (EC50 = 2.8 µg/ml) but not HepG2 or NCI H23 cells (EC50s = 28.3 and 26.4 µg/ml, respectively).{58034},{58035} 14-Deoxyandrographolide (10 and 25 µM) increases AMPK phosphorylation and glucose uptake in L6 myotubes and potentiates the effect of insulin to increase cell surface levels of GLUT4 in L6-GLUT4myc cells.{58037} It reduces blood glucose levels in rats in a model of streptozotocin-induced diabetes and in db/db diabetic mice when administered at a dose of 100 mg/kg. 14-Deoxyandrographolide reduces ethanol-induced hepatotoxicity in rats when administered at a dose of 15 mg/kg per day for the last four weeks of an eight-week ethanol exposure period.{58036} It also reduces protein carbonyl and thiobarbituric acid reactive substances (TBARS) levels and increases total glutathione (GSH) levels in isolated rat hepatocytes in the same model.
Brand:CaymanSKU:31140 - 10 mgAvailable on backorder
14-Deoxyandrographolide is a diterpene lactone that has been found in A. paniculata and has diverse biological activities, including anticancer, hepatoprotective, antioxidative, and antidiabetic properties.{58034},{58035},{58036},{58037} It inhibits the growth of HL-60 cells with a GI50 value of 25.46 µM and is cytotoxic to T47D cells (EC50 = 2.8 µg/ml) but not HepG2 or NCI H23 cells (EC50s = 28.3 and 26.4 µg/ml, respectively).{58034},{58035} 14-Deoxyandrographolide (10 and 25 µM) increases AMPK phosphorylation and glucose uptake in L6 myotubes and potentiates the effect of insulin to increase cell surface levels of GLUT4 in L6-GLUT4myc cells.{58037} It reduces blood glucose levels in rats in a model of streptozotocin-induced diabetes and in db/db diabetic mice when administered at a dose of 100 mg/kg. 14-Deoxyandrographolide reduces ethanol-induced hepatotoxicity in rats when administered at a dose of 15 mg/kg per day for the last four weeks of an eight-week ethanol exposure period.{58036} It also reduces protein carbonyl and thiobarbituric acid reactive substances (TBARS) levels and increases total glutathione (GSH) levels in isolated rat hepatocytes in the same model.
Brand:CaymanSKU:31140 - 5 mgAvailable on backorder
14-Deoxyandrographolide is a diterpene lactone that has been found in A. paniculata and has diverse biological activities, including anticancer, hepatoprotective, antioxidative, and antidiabetic properties.{58034},{58035},{58036},{58037} It inhibits the growth of HL-60 cells with a GI50 value of 25.46 µM and is cytotoxic to T47D cells (EC50 = 2.8 µg/ml) but not HepG2 or NCI H23 cells (EC50s = 28.3 and 26.4 µg/ml, respectively).{58034},{58035} 14-Deoxyandrographolide (10 and 25 µM) increases AMPK phosphorylation and glucose uptake in L6 myotubes and potentiates the effect of insulin to increase cell surface levels of GLUT4 in L6-GLUT4myc cells.{58037} It reduces blood glucose levels in rats in a model of streptozotocin-induced diabetes and in db/db diabetic mice when administered at a dose of 100 mg/kg. 14-Deoxyandrographolide reduces ethanol-induced hepatotoxicity in rats when administered at a dose of 15 mg/kg per day for the last four weeks of an eight-week ethanol exposure period.{58036} It also reduces protein carbonyl and thiobarbituric acid reactive substances (TBARS) levels and increases total glutathione (GSH) levels in isolated rat hepatocytes in the same model.
Brand:CaymanSKU:31140 - 500 µgAvailable on backorder
14-methyl Palmitic acid is a methylated fatty acid that has been found in bacteria, bovine milk fat, Aegean jellyfish (A. aurita), and one-humped camel (C. dromedarius) meat and fat.{40922,40923,38743,40924} It is also found in human breast milk and levels are decreased in mature breast milk compared to colostrum.{40925} 14-methyl Palmitic acid is produced in Florida manatee (T. manatus latirostris) liver in response to brevetoxin exposure.{40926} [Matreya, LLC. Catalog No. 1616]
Brand:CaymanSKU:24820 - 1 mgAvailable on backorder
14-methyl Palmitic acid is a methylated fatty acid that has been found in bacteria, bovine milk fat, Aegean jellyfish (A. aurita), and one-humped camel (C. dromedarius) meat and fat.{40922,40923,38743,40924} It is also found in human breast milk and levels are decreased in mature breast milk compared to colostrum.{40925} 14-methyl Palmitic acid is produced in Florida manatee (T. manatus latirostris) liver in response to brevetoxin exposure.{40926} [Matreya, LLC. Catalog No. 1616]
Brand:CaymanSKU:24820 - 5 mgAvailable on backorder
14-methyl Palmitic acid methyl ester is a methylated fatty acid methyl ester that has been found in A. indica leaf extract, S. alboflavus TD-1, and as a minor component in biodiesel produced from C. sorokiniana microalgae.{40917,40921,40919} It is a volatile compound released by maize that reduces growth of F. verticillioides in a concentration-dependent manner.{40920} 14-methyl Palmitic acid methyl ester has been used as a standard for the quantification of 14-methyl palmitic acid (Item No. 24820) in various foods by GC-MS.{40918} [Matreya, LLC. Catalog No. 1614]
Brand:CaymanSKU:24821 - 1 mgAvailable on backorder
14-methyl Palmitic acid methyl ester is a methylated fatty acid methyl ester that has been found in A. indica leaf extract, S. alboflavus TD-1, and as a minor component in biodiesel produced from C. sorokiniana microalgae.{40917,40921,40919} It is a volatile compound released by maize that reduces growth of F. verticillioides in a concentration-dependent manner.{40920} 14-methyl Palmitic acid methyl ester has been used as a standard for the quantification of 14-methyl palmitic acid (Item No. 24820) in various foods by GC-MS.{40918} [Matreya, LLC. Catalog No. 1614]
Brand:CaymanSKU:24821 - 10 mgAvailable on backorder
14-methyl Palmitic acid methyl ester is a methylated fatty acid methyl ester that has been found in A. indica leaf extract, S. alboflavus TD-1, and as a minor component in biodiesel produced from C. sorokiniana microalgae.{40917,40921,40919} It is a volatile compound released by maize that reduces growth of F. verticillioides in a concentration-dependent manner.{40920} 14-methyl Palmitic acid methyl ester has been used as a standard for the quantification of 14-methyl palmitic acid (Item No. 24820) in various foods by GC-MS.{40918} [Matreya, LLC. Catalog No. 1614]
Brand:CaymanSKU:24821 - 5 mgAvailable on backorder
14-methyl Pentadecanoic acid methyl ester is a methylated fatty acid methyl ester that has been found in S. zeai sea sponges as the fatty acyl component of zeamide, A. indica leaf extract, and C. vulgaris and H. pluvialis microalgae.{40928,40917,40927} It is a major component of the vancomycin-induced biofilm produced by vancomycin-resistant S. aureus (VRSA).{40929} 14-methyl Pentadecanoic acid methyl ester has been used as a standard for the quantification of 14-methyl pentadecanoic acid in various foods by GC-MS.{40918} [Matreya, LLC. Catalog No. 1601]
Brand:CaymanSKU:24813 - 1 mgAvailable on backorder
14-methyl Pentadecanoic acid methyl ester is a methylated fatty acid methyl ester that has been found in S. zeai sea sponges as the fatty acyl component of zeamide, A. indica leaf extract, and C. vulgaris and H. pluvialis microalgae.{40928,40917,40927} It is a major component of the vancomycin-induced biofilm produced by vancomycin-resistant S. aureus (VRSA).{40929} 14-methyl Pentadecanoic acid methyl ester has been used as a standard for the quantification of 14-methyl pentadecanoic acid in various foods by GC-MS.{40918} [Matreya, LLC. Catalog No. 1601]
Brand:CaymanSKU:24813 - 10 mgAvailable on backorder
14-methyl Pentadecanoic acid methyl ester is a methylated fatty acid methyl ester that has been found in S. zeai sea sponges as the fatty acyl component of zeamide, A. indica leaf extract, and C. vulgaris and H. pluvialis microalgae.{40928,40917,40927} It is a major component of the vancomycin-induced biofilm produced by vancomycin-resistant S. aureus (VRSA).{40929} 14-methyl Pentadecanoic acid methyl ester has been used as a standard for the quantification of 14-methyl pentadecanoic acid in various foods by GC-MS.{40918} [Matreya, LLC. Catalog No. 1601]
Brand:CaymanSKU:24813 - 5 mgAvailable on backorder
14-Pentadecenoic acid is a 15-carbon, long-chain fatty acid that contains an alkene functional group on the terminal carbon of its aliphatic tail. The oxidation pattern of this fatty acid resulting from growth of M. cerificans at the expense of the parent alkene has been reported.{31487} 14-Pentadecenoic acid has been used in the fabrication of fibrous scaffold biomaterials for tissue engineering applications and for the construction of metallomesogenic side-chain polymers that coat capillary columns used in gas chromatography.{31485,31486}
Brand:CaymanSKU:19724 -Available on backorder
14-Pentadecenoic acid is a 15-carbon, long-chain fatty acid that contains an alkene functional group on the terminal carbon of its aliphatic tail. The oxidation pattern of this fatty acid resulting from growth of M. cerificans at the expense of the parent alkene has been reported.{31487} 14-Pentadecenoic acid has been used in the fabrication of fibrous scaffold biomaterials for tissue engineering applications and for the construction of metallomesogenic side-chain polymers that coat capillary columns used in gas chromatography.{31485,31486}
Brand:CaymanSKU:19724 -Available on backorder
14-Pentadecenoic acid is a 15-carbon, long-chain fatty acid that contains an alkene functional group on the terminal carbon of its aliphatic tail. The oxidation pattern of this fatty acid resulting from growth of M. cerificans at the expense of the parent alkene has been reported.{31487} 14-Pentadecenoic acid has been used in the fabrication of fibrous scaffold biomaterials for tissue engineering applications and for the construction of metallomesogenic side-chain polymers that coat capillary columns used in gas chromatography.{31485,31486}
Brand:CaymanSKU:19724 -Available on backorder
14-Pentadecenoic acid is a 15-carbon, long-chain fatty acid that contains an alkene functional group on the terminal carbon of its aliphatic tail. The oxidation pattern of this fatty acid resulting from growth of M. cerificans at the expense of the parent alkene has been reported.{31487} 14-Pentadecenoic acid has been used in the fabrication of fibrous scaffold biomaterials for tissue engineering applications and for the construction of metallomesogenic side-chain polymers that coat capillary columns used in gas chromatography.{31485,31486}
Brand:CaymanSKU:19724 -Available on backorder
Leukotriene B4 (LTB4) is a dihydroxy fatty acid derived from arachidonic acid through the 5-lipoxygenase pathway.{521,948} It promotes a number of leukocyte functions including aggregation, stimulation of ion fluxes, enhancement of lysosomal enzyme release, superoxide anion production, chemotaxis, and chemokinesis.{329,82} At least two LTB4 receptors, termed BLT1 and BLT2, have been identified. 14,15-dehydro LTB4 is a LTB4 receptor antagonist that has a higher binding affinity for BLT1, demonstrating a Ki value of 27 nM, compared to BLT2, which has a Ki value of 473 nM.{8743} 14,15-dehydro LTB4 inhibits LTB4-induced release of lysozymes from rat polymorphonuclear leukoctyes with an IC50 value of 1 µM.{384}
Brand:CaymanSKU:20150 -Available on backorder
Leukotriene B4 (LTB4) is a dihydroxy fatty acid derived from arachidonic acid through the 5-lipoxygenase pathway.{521,948} It promotes a number of leukocyte functions including aggregation, stimulation of ion fluxes, enhancement of lysosomal enzyme release, superoxide anion production, chemotaxis, and chemokinesis.{329,82} At least two LTB4 receptors, termed BLT1 and BLT2, have been identified. 14,15-dehydro LTB4 is a LTB4 receptor antagonist that has a higher binding affinity for BLT1, demonstrating a Ki value of 27 nM, compared to BLT2, which has a Ki value of 473 nM.{8743} 14,15-dehydro LTB4 inhibits LTB4-induced release of lysozymes from rat polymorphonuclear leukoctyes with an IC50 value of 1 µM.{384}
Brand:CaymanSKU:20150 -Available on backorder
Leukotriene B4 (LTB4) is a dihydroxy fatty acid derived from arachidonic acid through the 5-lipoxygenase pathway.{521,948} It promotes a number of leukocyte functions including aggregation, stimulation of ion fluxes, enhancement of lysosomal enzyme release, superoxide anion production, chemotaxis, and chemokinesis.{329,82} At least two LTB4 receptors, termed BLT1 and BLT2, have been identified. 14,15-dehydro LTB4 is a LTB4 receptor antagonist that has a higher binding affinity for BLT1, demonstrating a Ki value of 27 nM, compared to BLT2, which has a Ki value of 473 nM.{8743} 14,15-dehydro LTB4 inhibits LTB4-induced release of lysozymes from rat polymorphonuclear leukoctyes with an IC50 value of 1 µM.{384}
Brand:CaymanSKU:20150 -Available on backorder
Epoxyeicosatrienoic acids (EETs), such as 11(12)-EET and 14(15)-EET, are cytochrome P450 metabolites of arachidonic acid that have been identified as endothelium-derived hyperpolarizing factors with vasodilator activity.{12391} 14,15-EE-5(Z)-E is a structural analog of 14,15-epoxyeicosatrienoic acids (14,15-EET) that antagonizes EET-induced relaxation of vascular smooth muscle.{14412} Relaxation of U46619-constricted bovine arteries by 14,15-EET could be inhibited approximately 80% by 14,15-EE-5(Z)-E at a concentration of 10 µM. 14,15-EE-5(Z)-E does not appear to antagonize nitric oxide- or iloprost-mediated vascular relaxation.
Brand:CaymanSKU:10004946 - 100 µgAvailable on backorder
Epoxyeicosatrienoic acids (EETs), such as 11(12)-EET and 14(15)-EET, are cytochrome P450 metabolites of arachidonic acid that have been identified as endothelium-derived hyperpolarizing factors with vasodilator activity.{12391} 14,15-EE-5(Z)-E is a structural analog of 14,15-epoxyeicosatrienoic acids (14,15-EET) that antagonizes EET-induced relaxation of vascular smooth muscle.{14412} Relaxation of U46619-constricted bovine arteries by 14,15-EET could be inhibited approximately 80% by 14,15-EE-5(Z)-E at a concentration of 10 µM. 14,15-EE-5(Z)-E does not appear to antagonize nitric oxide- or iloprost-mediated vascular relaxation.
Brand:CaymanSKU:10004946 - 25 µgAvailable on backorder
Epoxyeicosatrienoic acids (EETs), such as 11(12)-EET and 14(15)-EET, are cytochrome P450 metabolites of arachidonic acid that have been identified as endothelium-derived hyperpolarizing factors with vasodilator activity.{12391} 14,15-EE-5(Z)-E is a structural analog of 14,15-epoxyeicosatrienoic acids (14,15-EET) that antagonizes EET-induced relaxation of vascular smooth muscle.{14412} Relaxation of U46619-constricted bovine arteries by 14,15-EET could be inhibited approximately 80% by 14,15-EE-5(Z)-E at a concentration of 10 µM. 14,15-EE-5(Z)-E does not appear to antagonize nitric oxide- or iloprost-mediated vascular relaxation.
Brand:CaymanSKU:10004946 - 50 µgAvailable on backorder
Epoxyeicosatrienoic acids (EETs), such as 11(12)-EET and 14(15)-EET, are cytochrome P450 metabolites of arachidonic acid that have been identified as endothelium-derived hyperpolarizing factors with vasodilator activity.{12391} 14,15-EE-5(Z)-E is a structural analog of 14,15-epoxyeicosatrienoic acids (14,15-EET) that antagonizes EET-induced relaxation of vascular smooth muscle.{14412} Relaxation of U46619-constricted bovine arteries by 14,15-EET could be inhibited approximately 80% by 14,15-EE-5(Z)-E at a concentration of 10 µM. 14,15-EE-5(Z)-E does not appear to antagonize nitric oxide- or iloprost-mediated vascular relaxation.
Brand:CaymanSKU:10004946 - 500 µgAvailable on backorder
Epoxyeicosatrienoic acids (EETs), such as 11(12)-EET and 14(15)-EET, are cytochrome P450 metabolites of arachidonic acid that have been identified as endothelium-derived hyperpolarizing factors with vasodilator activity.{15770} 14,15-EE-8(Z)-E is a structural analog of 14(15)-EET that demonstrates potent vasodilator agonist activity in bovine coronary arteries similar to that of 14(15)-EET.{14714,14413}
Brand:CaymanSKU:10010486 - 100 µgAvailable on backorder
Epoxyeicosatrienoic acids (EETs), such as 11(12)-EET and 14(15)-EET, are cytochrome P450 metabolites of arachidonic acid that have been identified as endothelium-derived hyperpolarizing factors with vasodilator activity.{15770} 14,15-EE-8(Z)-E is a structural analog of 14(15)-EET that demonstrates potent vasodilator agonist activity in bovine coronary arteries similar to that of 14(15)-EET.{14714,14413}
Brand:CaymanSKU:10010486 - 25 µgAvailable on backorder
Epoxyeicosatrienoic acids (EETs), such as 11(12)-EET and 14(15)-EET, are cytochrome P450 metabolites of arachidonic acid that have been identified as endothelium-derived hyperpolarizing factors with vasodilator activity.{15770} 14,15-EE-8(Z)-E is a structural analog of 14(15)-EET that demonstrates potent vasodilator agonist activity in bovine coronary arteries similar to that of 14(15)-EET.{14714,14413}
Brand:CaymanSKU:10010486 - 50 µgAvailable on backorder
Epoxyeicosatrienoic acids (EETs), such as 11(12)-EET and 14(15)-EET, are cytochrome P450 metabolites of arachidonic acid that have been identified as endothelium-derived hyperpolarizing factors with vasodilator activity.{15770} 14,15-EE-8(Z)-E is a structural analog of 14(15)-EET that demonstrates potent vasodilator agonist activity in bovine coronary arteries similar to that of 14(15)-EET.{14714,14413}
Brand:CaymanSKU:10010486 - 500 µgAvailable on backorder
14,15-Leukotriene A4 (14,15-LTA4) methyl ester is an esterified form of 14,15-LTA4, a leukotriene isomer formed from arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) by 15-lipoxygenase (15-LO) that inhibits LTA4 hydrolase.{391,45244}
Brand:CaymanSKU:10011359 - 100 µgAvailable on backorder
14,15-Leukotriene A4 (14,15-LTA4) methyl ester is an esterified form of 14,15-LTA4, a leukotriene isomer formed from arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) by 15-lipoxygenase (15-LO) that inhibits LTA4 hydrolase.{391,45244}
Brand:CaymanSKU:10011359 - 25 µgAvailable on backorder
14,15-Leukotriene A4 (14,15-LTA4) methyl ester is an esterified form of 14,15-LTA4, a leukotriene isomer formed from arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) by 15-lipoxygenase (15-LO) that inhibits LTA4 hydrolase.{391,45244}
Brand:CaymanSKU:10011359 - 50 µgAvailable on backorder
Leukotrienes (LTs) are a group of acute inflammatory mediators derived from arachidonic acid in leukocytes. The majority of these metabolites are formed through the 5-lipoxygenase (5-LO) pathway.{11267} 14,15-LTC4 is a member of an alternate class of LTs synthesized by a pathway involving the dual actions of 15- and 12-LOs on arachidonic acid via 15-HpETE and 14,15-LTA4 intermediates.{453,391,15256,11160} 14,15-LTC4 is classified as an eoxin, because it is formed mostly by eosinophils.{15256} However, mast cells and nasal polyps can synthesize 14,15-LTC4 as well. Little is known about the physiological actions of 14,15-LTC4. It has weak contractile activity on both guinea pig ileum and pulmonary parenchyma in contrast to the effects of 5-LO-derived LTs.{11158,11187} However, in an in vitro permeability assay, 14,15-LTC4 can increase vascular permeability of human endothelial cell monolayers, with similar potency to that of 5-LO-derived LTs resulting in plasma leakage – a hallmark of inflammation.{15256}
Brand:CaymanSKU:10011360 - 100 µgAvailable on backorder
Leukotrienes (LTs) are a group of acute inflammatory mediators derived from arachidonic acid in leukocytes. The majority of these metabolites are formed through the 5-lipoxygenase (5-LO) pathway.{11267} 14,15-LTC4 is a member of an alternate class of LTs synthesized by a pathway involving the dual actions of 15- and 12-LOs on arachidonic acid via 15-HpETE and 14,15-LTA4 intermediates.{453,391,15256,11160} 14,15-LTC4 is classified as an eoxin, because it is formed mostly by eosinophils.{15256} However, mast cells and nasal polyps can synthesize 14,15-LTC4 as well. Little is known about the physiological actions of 14,15-LTC4. It has weak contractile activity on both guinea pig ileum and pulmonary parenchyma in contrast to the effects of 5-LO-derived LTs.{11158,11187} However, in an in vitro permeability assay, 14,15-LTC4 can increase vascular permeability of human endothelial cell monolayers, with similar potency to that of 5-LO-derived LTs resulting in plasma leakage – a hallmark of inflammation.{15256}
Brand:CaymanSKU:10011360 - 25 µgAvailable on backorder
Leukotrienes (LTs) are a group of acute inflammatory mediators derived from arachidonic acid in leukocytes. The majority of these metabolites are formed through the 5-lipoxygenase (5-LO) pathway.{11267} 14,15-LTC4 is a member of an alternate class of LTs synthesized by a pathway involving the dual actions of 15- and 12-LOs on arachidonic acid via 15-HpETE and 14,15-LTA4 intermediates.{453,391,15256,11160} 14,15-LTC4 is classified as an eoxin, because it is formed mostly by eosinophils.{15256} However, mast cells and nasal polyps can synthesize 14,15-LTC4 as well. Little is known about the physiological actions of 14,15-LTC4. It has weak contractile activity on both guinea pig ileum and pulmonary parenchyma in contrast to the effects of 5-LO-derived LTs.{11158,11187} However, in an in vitro permeability assay, 14,15-LTC4 can increase vascular permeability of human endothelial cell monolayers, with similar potency to that of 5-LO-derived LTs resulting in plasma leakage – a hallmark of inflammation.{15256}
Brand:CaymanSKU:10011360 - 50 µgAvailable on backorder
14,15-Leukotriene D4 (14,15-LTD4) is a member of an alternate class of LTs synthesized by a pathway involving the dual actions of 15- and 12-lipoxygenases (15- and 12-LOs) on arachidonic acid via 15-HpETE and 14,15-LTA4 intermediates.{453,391,15256,11160} 14,15-LTD4 is classified as an eoxin (EXD4), because it is formed mostly by eosinophils.{15256} However, mast cells and nasal polyps can synthesize 14,15-LTD4 as well. Little is known about the physiological actions of 14,15-LTD4. It has weak contractile activity on both guinea pig ileum and pulmonary parenchyma in contrast to the effects of 5-LO-derived LTs.{11158,11187} However, in an in vitro permeability assay, 14,15-LTD4 can increase vascular permeability of human endothelial cell monolayers, with similar potency to that of 5-LO-derived LTs, resulting in plasma leakage, a hallmark of inflammation.{15256}
Brand:CaymanSKU:10011361 - 100 µgAvailable on backorder
14,15-Leukotriene D4 (14,15-LTD4) is a member of an alternate class of LTs synthesized by a pathway involving the dual actions of 15- and 12-lipoxygenases (15- and 12-LOs) on arachidonic acid via 15-HpETE and 14,15-LTA4 intermediates.{453,391,15256,11160} 14,15-LTD4 is classified as an eoxin (EXD4), because it is formed mostly by eosinophils.{15256} However, mast cells and nasal polyps can synthesize 14,15-LTD4 as well. Little is known about the physiological actions of 14,15-LTD4. It has weak contractile activity on both guinea pig ileum and pulmonary parenchyma in contrast to the effects of 5-LO-derived LTs.{11158,11187} However, in an in vitro permeability assay, 14,15-LTD4 can increase vascular permeability of human endothelial cell monolayers, with similar potency to that of 5-LO-derived LTs, resulting in plasma leakage, a hallmark of inflammation.{15256}
Brand:CaymanSKU:10011361 - 25 µgAvailable on backorder
14,15-Leukotriene D4 (14,15-LTD4) is a member of an alternate class of LTs synthesized by a pathway involving the dual actions of 15- and 12-lipoxygenases (15- and 12-LOs) on arachidonic acid via 15-HpETE and 14,15-LTA4 intermediates.{453,391,15256,11160} 14,15-LTD4 is classified as an eoxin (EXD4), because it is formed mostly by eosinophils.{15256} However, mast cells and nasal polyps can synthesize 14,15-LTD4 as well. Little is known about the physiological actions of 14,15-LTD4. It has weak contractile activity on both guinea pig ileum and pulmonary parenchyma in contrast to the effects of 5-LO-derived LTs.{11158,11187} However, in an in vitro permeability assay, 14,15-LTD4 can increase vascular permeability of human endothelial cell monolayers, with similar potency to that of 5-LO-derived LTs, resulting in plasma leakage, a hallmark of inflammation.{15256}
Brand:CaymanSKU:10011361 - 50 µgAvailable on backorder
Leukotrienes (LTs) are a group of acute inflammatory mediators derived from arachidonic acid in leukocytes. The majority of these metabolites are formed through the 5-lipoxygenase (5-LO) pathway.{11267} 14,15-LTE4 is a metabolite of 14,15-LTC4 and 14,15-LTD4, an alternate class of LTs synthesized by a pathway involving the dual actions of 15- and 12-LOs on arachidonic acid via 15-HpETE and 14,15-LTA4 intermediates.{453,391,15256,11160} These metabolites are classified as eoxins because they are formed mostly by eosinophils.{15256} Mast cells and nasal polyps can synthesize 14,15-LTC4 as well, however metabolism to 14,15-LTE4 in these cells and tissue has not been documented. 14,15-LTE4 increases vascular permeability of human endothelial cell monolayers with about 10-fold less potency than LTC4, but approximately 100-fold greater potency than histamine.{15256}
Brand:CaymanSKU:10011362 - 100 µgAvailable on backorder
Leukotrienes (LTs) are a group of acute inflammatory mediators derived from arachidonic acid in leukocytes. The majority of these metabolites are formed through the 5-lipoxygenase (5-LO) pathway.{11267} 14,15-LTE4 is a metabolite of 14,15-LTC4 and 14,15-LTD4, an alternate class of LTs synthesized by a pathway involving the dual actions of 15- and 12-LOs on arachidonic acid via 15-HpETE and 14,15-LTA4 intermediates.{453,391,15256,11160} These metabolites are classified as eoxins because they are formed mostly by eosinophils.{15256} Mast cells and nasal polyps can synthesize 14,15-LTC4 as well, however metabolism to 14,15-LTE4 in these cells and tissue has not been documented. 14,15-LTE4 increases vascular permeability of human endothelial cell monolayers with about 10-fold less potency than LTC4, but approximately 100-fold greater potency than histamine.{15256}
Brand:CaymanSKU:10011362 - 25 µgAvailable on backorder
Leukotrienes (LTs) are a group of acute inflammatory mediators derived from arachidonic acid in leukocytes. The majority of these metabolites are formed through the 5-lipoxygenase (5-LO) pathway.{11267} 14,15-LTE4 is a metabolite of 14,15-LTC4 and 14,15-LTD4, an alternate class of LTs synthesized by a pathway involving the dual actions of 15- and 12-LOs on arachidonic acid via 15-HpETE and 14,15-LTA4 intermediates.{453,391,15256,11160} These metabolites are classified as eoxins because they are formed mostly by eosinophils.{15256} Mast cells and nasal polyps can synthesize 14,15-LTC4 as well, however metabolism to 14,15-LTE4 in these cells and tissue has not been documented. 14,15-LTE4 increases vascular permeability of human endothelial cell monolayers with about 10-fold less potency than LTC4, but approximately 100-fold greater potency than histamine.{15256}
Brand:CaymanSKU:10011362 - 50 µgAvailable on backorder
14(S)-HDHA is an oxygenation product formed by 12-lipoxygenase (12-LO) or 15-LO processing of docosahexaenoic acid (DHA; Item No. 90310).{16640} It is a precursor to the pro-resolving mediator maresin 1 (Item No. 10878) and has been found in peritoneal exudates isolated from a mouse model of zymosan-induced peritonitis.
Brand:CaymanSKU:- 14(S)-HDHA is an oxygenation product formed by 12-lipoxygenase (12-LO) or 15-LO processing of docosahexaenoic acid (DHA; Item No. 90310).{16640} It is a precursor to the pro-resolving mediator maresin 1 (Item No. 10878) and has been found in peritoneal exudates isolated from a mouse model of zymosan-induced peritonitis.
Brand:CaymanSKU:- 14(S)-HDHA is an oxygenation product formed by 12-lipoxygenase (12-LO) or 15-LO processing of docosahexaenoic acid (DHA; Item No. 90310).{16640} It is a precursor to the pro-resolving mediator maresin 1 (Item No. 10878) and has been found in peritoneal exudates isolated from a mouse model of zymosan-induced peritonitis.
Brand:CaymanSKU:-
14(S)-HDHA is an oxygenation product formed by 12-lipoxygenase (12-LO) or 15-LO processing of docosahexaenoic acid (DHA; Item No. 90310).{16640} It is a precursor to the pro-resolving mediator maresin 1 (Item No. 10878) and has been found in peritoneal exudates isolated from a mouse model of zymosan-induced peritonitis. 14(S)-HDHA MaxSpec® standard is a quantitative grade standard of 14(S)-HDHA (Item No. 15253) that has been prepared specifically for mass spectrometry and related applications where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This 14(S)-HDHA MaxSpec® standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality.
Brand:CaymanSKU:29142 - 10 µgAvailable on backorder
14(Z)-Eicosenoic acid is a monounsaturated fatty acid. It is found in small quantities in marine life including the sponge (Tedania dirhaphis) and goldfish (Carassius auratus).{14592,14593} Potentially it could be the product of fatty acid chain elongation of 12(Z)-oleic acid.
Brand:CaymanSKU:10009375 - 1 mgAvailable on backorder
14(Z)-Eicosenoic acid is a monounsaturated fatty acid. It is found in small quantities in marine life including the sponge (Tedania dirhaphis) and goldfish (Carassius auratus).{14592,14593} Potentially it could be the product of fatty acid chain elongation of 12(Z)-oleic acid.
Brand:CaymanSKU:10009375 - 10 mgAvailable on backorder
14(Z)-Eicosenoic acid is a monounsaturated fatty acid. It is found in small quantities in marine life including the sponge (Tedania dirhaphis) and goldfish (Carassius auratus).{14592,14593} Potentially it could be the product of fatty acid chain elongation of 12(Z)-oleic acid.
Brand:CaymanSKU:10009375 - 25 mgAvailable on backorder
14(Z)-Eicosenoic acid is a monounsaturated fatty acid. It is found in small quantities in marine life including the sponge (Tedania dirhaphis) and goldfish (Carassius auratus).{14592,14593} Potentially it could be the product of fatty acid chain elongation of 12(Z)-oleic acid.
Brand:CaymanSKU:10009375 - 5 mgAvailable on backorder
1400W is a potent, selective inhibitor of iNOS.{4277} Using purified human iNOS, nNOS, and eNOS, 1400W exhibits Ki values of 7 nM, 2 µM, and 50 µM, respectively.{4277} In rat aortic rings it is at least 1,000-fold more potent against iNOS compared to eNOS.{4277} In mice bearing a murine mammary carcinoma, continuous infusion of 1400W at a rate of 10 mg/kg for 6 days decreased tumor weight approximately 50% compared to controls.{5066}
Brand:CaymanSKU:81520 - 10 mgAvailable on backorder
1400W is a potent, selective inhibitor of iNOS.{4277} Using purified human iNOS, nNOS, and eNOS, 1400W exhibits Ki values of 7 nM, 2 µM, and 50 µM, respectively.{4277} In rat aortic rings it is at least 1,000-fold more potent against iNOS compared to eNOS.{4277} In mice bearing a murine mammary carcinoma, continuous infusion of 1400W at a rate of 10 mg/kg for 6 days decreased tumor weight approximately 50% compared to controls.{5066}
Brand:CaymanSKU:81520 - 100 mgAvailable on backorder
1400W is a potent, selective inhibitor of iNOS.{4277} Using purified human iNOS, nNOS, and eNOS, 1400W exhibits Ki values of 7 nM, 2 µM, and 50 µM, respectively.{4277} In rat aortic rings it is at least 1,000-fold more potent against iNOS compared to eNOS.{4277} In mice bearing a murine mammary carcinoma, continuous infusion of 1400W at a rate of 10 mg/kg for 6 days decreased tumor weight approximately 50% compared to controls.{5066}
Brand:CaymanSKU:81520 - 5 mgAvailable on backorder
1400W is a potent, selective inhibitor of iNOS.{4277} Using purified human iNOS, nNOS, and eNOS, 1400W exhibits Ki values of 7 nM, 2 µM, and 50 µM, respectively.{4277} In rat aortic rings it is at least 1,000-fold more potent against iNOS compared to eNOS.{4277} In mice bearing a murine mammary carcinoma, continuous infusion of 1400W at a rate of 10 mg/kg for 6 days decreased tumor weight approximately 50% compared to controls.{5066}
Brand:CaymanSKU:81520 - 50 mgAvailable on backorder
14S(15R)-EET is an oxylipin and a cytochrome P450 metabolite of arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607).{52397} 14S(15R)-EET binds to isolated guinea pig monocytes with a Ki value of 612.5 nM in a competitive binding assay using [3H]14(15)-EET.{52398} It induces dilation of precontracted isolated canine epicardial arterioles (EC50 = 4 pM) and denuded porcine subepicardial arterioles (EC50 = 3 pM).{52399} Unlike 14R(15S)-EET, 14S(15R)-EET does not inhibit COX in enzyme assays or isolated platelets.{642}
Brand:CaymanSKU:28631 - 10 µgAvailable on backorder
14S(15R)-EET is an oxylipin and a cytochrome P450 metabolite of arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607).{52397} 14S(15R)-EET binds to isolated guinea pig monocytes with a Ki value of 612.5 nM in a competitive binding assay using [3H]14(15)-EET.{52398} It induces dilation of precontracted isolated canine epicardial arterioles (EC50 = 4 pM) and denuded porcine subepicardial arterioles (EC50 = 3 pM).{52399} Unlike 14R(15S)-EET, 14S(15R)-EET does not inhibit COX in enzyme assays or isolated platelets.{642}
Brand:CaymanSKU:28631 - 100 µgAvailable on backorder
14S(15R)-EET is an oxylipin and a cytochrome P450 metabolite of arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607).{52397} 14S(15R)-EET binds to isolated guinea pig monocytes with a Ki value of 612.5 nM in a competitive binding assay using [3H]14(15)-EET.{52398} It induces dilation of precontracted isolated canine epicardial arterioles (EC50 = 4 pM) and denuded porcine subepicardial arterioles (EC50 = 3 pM).{52399} Unlike 14R(15S)-EET, 14S(15R)-EET does not inhibit COX in enzyme assays or isolated platelets.{642}
Brand:CaymanSKU:28631 - 25 µgAvailable on backorder
14S(15R)-EET is an oxylipin and a cytochrome P450 metabolite of arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607).{52397} 14S(15R)-EET binds to isolated guinea pig monocytes with a Ki value of 612.5 nM in a competitive binding assay using [3H]14(15)-EET.{52398} It induces dilation of precontracted isolated canine epicardial arterioles (EC50 = 4 pM) and denuded porcine subepicardial arterioles (EC50 = 3 pM).{52399} Unlike 14R(15S)-EET, 14S(15R)-EET does not inhibit COX in enzyme assays or isolated platelets.{642}
Brand:CaymanSKU:28631 - 50 µgAvailable on backorder
14α-hydroxy Paspalinine is an indole diterpene fungal metabolite originally isolated from A. nomius.{43042} Dietary administration of 14α-hydroxy paspalinine (100 ppm) reduces weight gain of H. zea first instar larvae by 91%.
Brand:CaymanSKU:25081 - 1 mgAvailable on backorder
14α-hydroxy Paspalinine is an indole diterpene fungal metabolite originally isolated from A. nomius.{43042} Dietary administration of 14α-hydroxy paspalinine (100 ppm) reduces weight gain of H. zea first instar larvae by 91%.
Brand:CaymanSKU:25081 - 5 mgAvailable on backorder
15-acetoxy Scirpenol is a trichothecene mycotoxin that is produced predominantly by members of the Fusarium genus.{31918} It can induce apoptotic cell death in human Jurkat T cells.{31922}
Brand:CaymanSKU:11431 - 1 mgAvailable on backorder
15-acetoxy Scirpenol is a trichothecene mycotoxin that is produced predominantly by members of the Fusarium genus.{31918} It can induce apoptotic cell death in human Jurkat T cells.{31922}
Brand:CaymanSKU:11431 - 5 mgAvailable on backorder
15-Acetyldeoxy nivalenol is a trichothecene mycotoxin produced by certain species of the fungus Fusarium, particularly those found on cereal crops.{31919} It is an acetylated derivative of 4-deoxy nivalenol (DON; Item No. 11428) that can be converted to DON in the body. 15-Acetyldeoxy nivalenol induces vomiting and anorexia in livestock and experimental animals and its toxicity compared with DON is dependent upon the route of administration.{41122,41121} It also changes brain bioamine neurotransmitter levels in pigs and chickens.{24415}
Brand:CaymanSKU:11430 - 1 mgAvailable on backorder
15-deoxy-Δ12,14-Prostaglandin A1 (15-deoxy-Δ12,14-PGA1) is a synthetic PGA1 analog. It shares common structural features with 15-deoxy-Δ12,14-PGJ2, which is a ligand for PPARγ.{1428} Antimitotic and antitumor activity have been reported for a similar analog, but there are no published reports on the biological activity of 15-deoxy-Δ12,14-PGA1 at this time.{334}
Brand:CaymanSKU:10065 - 1 mgAvailable on backorder
15-deoxy-Δ12,14-Prostaglandin A1 (15-deoxy-Δ12,14-PGA1) is a synthetic PGA1 analog. It shares common structural features with 15-deoxy-Δ12,14-PGJ2, which is a ligand for PPARγ.{1428} Antimitotic and antitumor activity have been reported for a similar analog, but there are no published reports on the biological activity of 15-deoxy-Δ12,14-PGA1 at this time.{334}
Brand:CaymanSKU:10065 - 5 mgAvailable on backorder
15-deoxy-Δ12,14-Prostaglandin A1 (15-deoxy-Δ12,14-PGA1) is a synthetic PGA1 analog. It shares common structural features with 15-deoxy-Δ12,14-PGJ2, which is a ligand for PPARγ.{1428} Antimitotic and antitumor activity have been reported for a similar analog, but there are no published reports on the biological activity of 15-deoxy-Δ12,14-PGA1 at this time.{334}
Brand:CaymanSKU:10065 - 500 µgAvailable on backorder
15-deoxy-Δ12,14-PGA2 is a synthetic analog of PGA2. It shares common structural features with 15-deoxy-Δ12,14-PGJ2, which is a ligand for PPARγ.{1428,1424} Antimitotic and antitumor activity have been reported for a similar analog,{334} but there are no published reports on the biological activity of 15-deoxy-Δ12,14-PGA2 at this time.
Brand:CaymanSKU:10265 - 1 mgAvailable on backorder
15-deoxy-Δ12,14-PGA2 is a synthetic analog of PGA2. It shares common structural features with 15-deoxy-Δ12,14-PGJ2, which is a ligand for PPARγ.{1428,1424} Antimitotic and antitumor activity have been reported for a similar analog,{334} but there are no published reports on the biological activity of 15-deoxy-Δ12,14-PGA2 at this time.
Brand:CaymanSKU:10265 - 5 mgAvailable on backorder
15-deoxy-Δ12,14-PGA2 is a synthetic analog of PGA2. It shares common structural features with 15-deoxy-Δ12,14-PGJ2, which is a ligand for PPARγ.{1428,1424} Antimitotic and antitumor activity have been reported for a similar analog,{334} but there are no published reports on the biological activity of 15-deoxy-Δ12,14-PGA2 at this time.
Brand:CaymanSKU:10265 - 500 µgAvailable on backorder
15-deoxy-Δ12,14-PGD2 is a metabolite of PGD2 (Item No. 12010).{11797} It is an agonist of PGD2 receptor 2 (DP2) that binds DP2 (Ki = 50 nM for the mouse receptor expressed in HEK293 cell membranes) and induces activation of eosinophils (EC50 = 8 nM).{11399,11055} It also stimulates the recruitment of steroid receptor coactivator-1 (SRC-1) to peroxisome proliferator-activated receptor γ (PPARγ) and induces PPARγ-mediated transcription in a reporter assay when used at a concentration of 5 µM.{11797} 15-deoxy-Δ12,14-PGD2 is cytotoxic to L1210 murine leukemia cells (IC50 = 0.3 µg/ml).{1424} It inhibits ADP-induced platelet aggregation (IC50 = 320 ng/ml) less potently than PGD2.{1139}
Brand:CaymanSKU:12700 - 1 mgAvailable on backorder