Chemicals
Showing 30001–30150 of 41137 results
-
O4I1 is an inducer of Oct3/4 expression and translation in diverse human cell lines (increases Oct3/4 mRNA in HEK293 cells by 2.5- and 4-fold at 10 and 20 μM, respectively).{33095} It also induces Oct3/4 expression and translation in terminally differentiated human fibroblasts.{33095} Through this action, O4I1 promotes the expression of pluripotency-associated genes in human neonatal foreskin fibroblasts.
Brand:CaymanSKU:19935 -Available on backorder
Octamer-binding transcription factor 3/4 (Oct3/4) is a transcription factor that has key roles in early embryogenesis and embryonic stem cell pluripotency.{22412,22414} O4I2 is a potent inducer of Oct3/4 expression and translation in human cell lines, including embryonic kidney HEK293, embryonic placental NCCIT, and Oct-deficient HeLa cells.{30986} It also induces Oct3/4 expression and translation in terminally differentiated human fibroblasts. Through this action, O4I2 promotes the expression of pluripotency-associated genes in human neonatal foreskin fibroblasts.{30986}
Brand:CaymanSKU:-Available on backorder
Octamer-binding transcription factor 3/4 (Oct3/4) is a transcription factor that has key roles in early embryogenesis and embryonic stem cell pluripotency.{22412,22414} O4I2 is a potent inducer of Oct3/4 expression and translation in human cell lines, including embryonic kidney HEK293, embryonic placental NCCIT, and Oct-deficient HeLa cells.{30986} It also induces Oct3/4 expression and translation in terminally differentiated human fibroblasts. Through this action, O4I2 promotes the expression of pluripotency-associated genes in human neonatal foreskin fibroblasts.{30986}
Brand:CaymanSKU:-Available on backorder
Octamer-binding transcription factor 3/4 (Oct3/4) is a transcription factor that has key roles in early embryogenesis and embryonic stem cell pluripotency.{22412,22414} O4I2 is a potent inducer of Oct3/4 expression and translation in human cell lines, including embryonic kidney HEK293, embryonic placental NCCIT, and Oct-deficient HeLa cells.{30986} It also induces Oct3/4 expression and translation in terminally differentiated human fibroblasts. Through this action, O4I2 promotes the expression of pluripotency-associated genes in human neonatal foreskin fibroblasts.{30986}
Brand:CaymanSKU:-Available on backorder
Octamer-binding transcription factor 3/4 (Oct3/4) is a transcription factor that has key roles in early embryogenesis and embryonic stem cell pluripotency.{22412,22414} O4I2 is a potent inducer of Oct3/4 expression and translation in human cell lines, including embryonic kidney HEK293, embryonic placental NCCIT, and Oct-deficient HeLa cells.{30986} It also induces Oct3/4 expression and translation in terminally differentiated human fibroblasts. Through this action, O4I2 promotes the expression of pluripotency-associated genes in human neonatal foreskin fibroblasts.{30986}
Brand:CaymanSKU:-Available on backorder
O6-Alkylguanine-DNA alkyltransferase (AGT, also known as methylguanine DNA methyltransferase, or MGMT) is a DNA repair protein that directly removes alkyl groups located on the O6-position of guanine from DNA, restoring DNA integrity in a single step.{26735} In the process, AGT is alkylated and irreversibly inactivated.{26735} O6-Benzylguanine is a guanine analog with antineoplastic activity. It serves as a pseudosubstrate for AGT, transferring a benzyl moiety to the active site cysteine of the enzyme. This leads to irreversible inactivation, with 40% reduction in alkyltransferase activity of recombinant human AGT achieved at 0.06 µM.{26730,26728} O6-Benzylguanine is effective in vivo as well as in vitro.{26733} Inactivation of AGT increases the chemotherapeutic effectiveness of chloroethylating and methylating agents.{26725}
Brand:CaymanSKU:-Out of stock
O6-Alkylguanine-DNA alkyltransferase (AGT, also known as methylguanine DNA methyltransferase, or MGMT) is a DNA repair protein that directly removes alkyl groups located on the O6-position of guanine from DNA, restoring DNA integrity in a single step.{26735} In the process, AGT is alkylated and irreversibly inactivated.{26735} O6-Benzylguanine is a guanine analog with antineoplastic activity. It serves as a pseudosubstrate for AGT, transferring a benzyl moiety to the active site cysteine of the enzyme. This leads to irreversible inactivation, with 40% reduction in alkyltransferase activity of recombinant human AGT achieved at 0.06 µM.{26730,26728} O6-Benzylguanine is effective in vivo as well as in vitro.{26733} Inactivation of AGT increases the chemotherapeutic effectiveness of chloroethylating and methylating agents.{26725}
Brand:CaymanSKU:-Out of stock
O6-Alkylguanine-DNA alkyltransferase (AGT, also known as methylguanine DNA methyltransferase, or MGMT) is a DNA repair protein that directly removes alkyl groups located on the O6-position of guanine from DNA, restoring DNA integrity in a single step.{26735} In the process, AGT is alkylated and irreversibly inactivated.{26735} O6-Benzylguanine is a guanine analog with antineoplastic activity. It serves as a pseudosubstrate for AGT, transferring a benzyl moiety to the active site cysteine of the enzyme. This leads to irreversible inactivation, with 40% reduction in alkyltransferase activity of recombinant human AGT achieved at 0.06 µM.{26730,26728} O6-Benzylguanine is effective in vivo as well as in vitro.{26733} Inactivation of AGT increases the chemotherapeutic effectiveness of chloroethylating and methylating agents.{26725}
Brand:CaymanSKU:-Out of stock
O6-Alkylguanine-DNA alkyltransferase (AGT, also known as methylguanine DNA methyltransferase, or MGMT) is a DNA repair protein that directly removes alkyl groups located on the O6-position of guanine from DNA, restoring DNA integrity in a single step.{26735} In the process, AGT is alkylated and irreversibly inactivated.{26735} O6-Benzylguanine is a guanine analog with antineoplastic activity. It serves as a pseudosubstrate for AGT, transferring a benzyl moiety to the active site cysteine of the enzyme. This leads to irreversible inactivation, with 40% reduction in alkyltransferase activity of recombinant human AGT achieved at 0.06 µM.{26730,26728} O6-Benzylguanine is effective in vivo as well as in vitro.{26733} Inactivation of AGT increases the chemotherapeutic effectiveness of chloroethylating and methylating agents.{26725}
Brand:CaymanSKU:-Out of stock
Octamer-binding transcription factor 4 (Oct4) is a transcription factor that, with Sox2, Klf4, and c-Myc, is involved in the reprogramming of somatic cells to produce pluripotent stem cells.{22412,22414} OAC1 is an Oct4-activating compound that activates expression through the Oct4 gene promoter.{22003} In cells expressing Oct4 with Sox2, Klf4, and c-Myc, OAC1 (1 μM) enhances reprogramming efficiency by increasing the rate of production of induced pluripotent stem cells (iPSCs) from embryonic fibroblasts.{22003} The iPSCs developed using OAC1 retain the capacity for pluripotent differentiation, whether evaluated in vitro or in vivo.{22003}
Brand:CaymanSKU:-Octamer-binding transcription factor 4 (Oct4) is a transcription factor that, with Sox2, Klf4, and c-Myc, is involved in the reprogramming of somatic cells to produce pluripotent stem cells.{22412,22414} OAC1 is an Oct4-activating compound that activates expression through the Oct4 gene promoter.{22003} In cells expressing Oct4 with Sox2, Klf4, and c-Myc, OAC1 (1 μM) enhances reprogramming efficiency by increasing the rate of production of induced pluripotent stem cells (iPSCs) from embryonic fibroblasts.{22003} The iPSCs developed using OAC1 retain the capacity for pluripotent differentiation, whether evaluated in vitro or in vivo.{22003}
Brand:CaymanSKU:-Octamer-binding transcription factor 4 (Oct4) is a transcription factor that, with Sox2, Klf4, and c-Myc, is involved in the reprogramming of somatic cells to produce pluripotent stem cells.{22412,22414} OAC1 is an Oct4-activating compound that activates expression through the Oct4 gene promoter.{22003} In cells expressing Oct4 with Sox2, Klf4, and c-Myc, OAC1 (1 μM) enhances reprogramming efficiency by increasing the rate of production of induced pluripotent stem cells (iPSCs) from embryonic fibroblasts.{22003} The iPSCs developed using OAC1 retain the capacity for pluripotent differentiation, whether evaluated in vitro or in vivo.{22003}
Brand:CaymanSKU:-Octamer-binding transcription factor 4 (Oct4) is a transcription factor which, with Sox2, Klf4, and c-Myc, is involved in the reprogramming of somatic cells to produce pluripotent stem cells.{22412,22414} OAC2 is an Oct4-activating compound which activates expression through the Oct4 gene promoter.{22003} In cells expressing Oct4 with Sox2, Klf4, and c-Myc, OAC2 (1 μM) enhances reprogramming efficiency by increasing the rate of production of induced pluripotent stem cells (iPSCs) from embryonic fibroblasts.{22003} The iPSCs developed using OAC2 retain the capacity for pluripotent differentiation, whether evaluated in vitro or in vivo.{22003}
Brand:CaymanSKU:-Octamer-binding transcription factor 4 (Oct4) is a transcription factor which, with Sox2, Klf4, and c-Myc, is involved in the reprogramming of somatic cells to produce pluripotent stem cells.{22412,22414} OAC2 is an Oct4-activating compound which activates expression through the Oct4 gene promoter.{22003} In cells expressing Oct4 with Sox2, Klf4, and c-Myc, OAC2 (1 μM) enhances reprogramming efficiency by increasing the rate of production of induced pluripotent stem cells (iPSCs) from embryonic fibroblasts.{22003} The iPSCs developed using OAC2 retain the capacity for pluripotent differentiation, whether evaluated in vitro or in vivo.{22003}
Brand:CaymanSKU:-Octamer-binding transcription factor 4 (Oct4) is a transcription factor which, with Sox2, Klf4, and c-Myc, is involved in the reprogramming of somatic cells to produce pluripotent stem cells.{22412,22414} OAC2 is an Oct4-activating compound which activates expression through the Oct4 gene promoter.{22003} In cells expressing Oct4 with Sox2, Klf4, and c-Myc, OAC2 (1 μM) enhances reprogramming efficiency by increasing the rate of production of induced pluripotent stem cells (iPSCs) from embryonic fibroblasts.{22003} The iPSCs developed using OAC2 retain the capacity for pluripotent differentiation, whether evaluated in vitro or in vivo.{22003}
Brand:CaymanSKU:-Octamer-binding transcription factor 4 (Oct4) is a transcription factor which, with Sox2, Klf4, and c-Myc, is involved in the reprogramming of somatic cells to produce pluripotent stem cells.{22412,22414} OAC3 is an Oct4-activating compound which activates expression through the Oct4 gene promoter.{22003} In cells expressing Oct4 with Sox2, Klf4, and c-Myc, OAC3 (1 μM) enhances reprogramming efficiency by increasing the rate of production of induced pluripotent stem cells from embryonic fibroblasts.{22003}
Brand:CaymanSKU:-Octamer-binding transcription factor 4 (Oct4) is a transcription factor which, with Sox2, Klf4, and c-Myc, is involved in the reprogramming of somatic cells to produce pluripotent stem cells.{22412,22414} OAC3 is an Oct4-activating compound which activates expression through the Oct4 gene promoter.{22003} In cells expressing Oct4 with Sox2, Klf4, and c-Myc, OAC3 (1 μM) enhances reprogramming efficiency by increasing the rate of production of induced pluripotent stem cells from embryonic fibroblasts.{22003}
Brand:CaymanSKU:-Octamer-binding transcription factor 4 (Oct4) is a transcription factor which, with Sox2, Klf4, and c-Myc, is involved in the reprogramming of somatic cells to produce pluripotent stem cells.{22412,22414} OAC3 is an Oct4-activating compound which activates expression through the Oct4 gene promoter.{22003} In cells expressing Oct4 with Sox2, Klf4, and c-Myc, OAC3 (1 μM) enhances reprogramming efficiency by increasing the rate of production of induced pluripotent stem cells from embryonic fibroblasts.{22003}
Brand:CaymanSKU:-OBA-09 is an ester of pyruvate and salicylic acid that has neuroprotective properties.{45395} It decreases lactate dehydrogenase (LDH) release and prevents cell death induced by NMDA or zinc, and reduces the production of reactive oxygen species (ROS) induced by oxygen-glucose deprivation in mixed rat primary cortical cells when used at concentrations of 10 and 15 mM. OBA-09 (10 mg/kg) reduces infarct volume by 89.9% and decreases expression of IL-1β, inducible nitric oxide synthase (iNOS), COX-2, and TNF-α in the brain in a rat model of ischemia induced by middle cerebral artery occlusion (MCAO).{45395,45396} It improves motor performance in the rotarod test in the same model when administered at a dose of 10 mg/kg.{45395}
Brand:CaymanSKU:21918 -Out of stock
OBA-09 is an ester of pyruvate and salicylic acid that has neuroprotective properties.{45395} It decreases lactate dehydrogenase (LDH) release and prevents cell death induced by NMDA or zinc, and reduces the production of reactive oxygen species (ROS) induced by oxygen-glucose deprivation in mixed rat primary cortical cells when used at concentrations of 10 and 15 mM. OBA-09 (10 mg/kg) reduces infarct volume by 89.9% and decreases expression of IL-1β, inducible nitric oxide synthase (iNOS), COX-2, and TNF-α in the brain in a rat model of ischemia induced by middle cerebral artery occlusion (MCAO).{45395,45396} It improves motor performance in the rotarod test in the same model when administered at a dose of 10 mg/kg.{45395}
Brand:CaymanSKU:21918 -Out of stock
OBA-09 is an ester of pyruvate and salicylic acid that has neuroprotective properties.{45395} It decreases lactate dehydrogenase (LDH) release and prevents cell death induced by NMDA or zinc, and reduces the production of reactive oxygen species (ROS) induced by oxygen-glucose deprivation in mixed rat primary cortical cells when used at concentrations of 10 and 15 mM. OBA-09 (10 mg/kg) reduces infarct volume by 89.9% and decreases expression of IL-1β, inducible nitric oxide synthase (iNOS), COX-2, and TNF-α in the brain in a rat model of ischemia induced by middle cerebral artery occlusion (MCAO).{45395,45396} It improves motor performance in the rotarod test in the same model when administered at a dose of 10 mg/kg.{45395}
Brand:CaymanSKU:21918 -Out of stock
OBA-09 is an ester of pyruvate and salicylic acid that has neuroprotective properties.{45395} It decreases lactate dehydrogenase (LDH) release and prevents cell death induced by NMDA or zinc, and reduces the production of reactive oxygen species (ROS) induced by oxygen-glucose deprivation in mixed rat primary cortical cells when used at concentrations of 10 and 15 mM. OBA-09 (10 mg/kg) reduces infarct volume by 89.9% and decreases expression of IL-1β, inducible nitric oxide synthase (iNOS), COX-2, and TNF-α in the brain in a rat model of ischemia induced by middle cerebral artery occlusion (MCAO).{45395,45396} It improves motor performance in the rotarod test in the same model when administered at a dose of 10 mg/kg.{45395}
Brand:CaymanSKU:21918 -Out of stock
Obafluorin is a β-lactone antibiotic that has been found in P. fluorescens.{52064} It is active against S. aureus, S. faecalis, K. pneumoniae, and P. vulgaris (MIC = 125 μg/ml for all).
Brand:CaymanSKU:25731 - 1 mgAvailable on backorder
Obafluorin is a β-lactone antibiotic that has been found in P. fluorescens.{52064} It is active against S. aureus, S. faecalis, K. pneumoniae, and P. vulgaris (MIC = 125 μg/ml for all).
Brand:CaymanSKU:25731 - 5 mgAvailable on backorder
Obafluorin is a β-lactone antibiotic that has been found in P. fluorescens.{52064} It is active against S. aureus, S. faecalis, K. pneumoniae, and P. vulgaris (MIC = 125 μg/ml for all).
Brand:CaymanSKU:25731 - 500 µgAvailable on backorder
Obatoclax is an antagonist of Bcl-2 family members containing four Bcl-2 homology domains, including Bcl-2, Bcl-W, Bcl-xL, and Mcl-1 (Kd = ~500 nM).{24297} It prevents the interaction of these pro-survival proteins with Bax or Bak, thereby inducing apoptosis with up-regulation of Bim, induced cytochrome c release, and activation of caspase-3.{24296,16717} Obstoclax also induces autophagy in mouse embryo fibroblasts and in HeLa cells.{24298} This compound inhibits the growth of cancer cell lines and primary cancer isolates.{16717,24296}
Brand:CaymanSKU:11499 - 1 mgAvailable on backorder
Obatoclax is an antagonist of Bcl-2 family members containing four Bcl-2 homology domains, including Bcl-2, Bcl-W, Bcl-xL, and Mcl-1 (Kd = ~500 nM).{24297} It prevents the interaction of these pro-survival proteins with Bax or Bak, thereby inducing apoptosis with up-regulation of Bim, induced cytochrome c release, and activation of caspase-3.{24296,16717} Obstoclax also induces autophagy in mouse embryo fibroblasts and in HeLa cells.{24298} This compound inhibits the growth of cancer cell lines and primary cancer isolates.{16717,24296}
Brand:CaymanSKU:11499 - 10 mgAvailable on backorder
Obatoclax is an antagonist of Bcl-2 family members containing four Bcl-2 homology domains, including Bcl-2, Bcl-W, Bcl-xL, and Mcl-1 (Kd = ~500 nM).{24297} It prevents the interaction of these pro-survival proteins with Bax or Bak, thereby inducing apoptosis with up-regulation of Bim, induced cytochrome c release, and activation of caspase-3.{24296,16717} Obstoclax also induces autophagy in mouse embryo fibroblasts and in HeLa cells.{24298} This compound inhibits the growth of cancer cell lines and primary cancer isolates.{16717,24296}
Brand:CaymanSKU:11499 - 5 mgAvailable on backorder
Obatoclax is an antagonist of Bcl-2 family members containing four Bcl-2 homology domains, including Bcl-2, Bcl-W, Bcl-xL, and Mcl-1 (Kd = ~500 nM).{24297} It prevents the interaction of these pro-survival proteins with Bax or Bak, thereby inducing apoptosis with up-regulation of Bim, induced cytochrome c release, and activation of caspase-3.{24296,16717} Obstoclax also induces autophagy in mouse embryo fibroblasts and in HeLa cells.{24298} This compound inhibits the growth of cancer cell lines and primary cancer isolates.{16717,24296}
Brand:CaymanSKU:11499 - 50 mgAvailable on backorder
Obestatin is a 23 amino acid peptide hormone with a conserved C-terminal glycine residue and amidation site that is formed by cleavage of the ghrelin and obestatin prepropeptide.{13636} It binds to the orphan receptor GPR39 (Kd = 1 nM) and stimulates cAMP production in CHO and HEK293 cells overexpressing human GPR39. Obestatin inhibits contraction of isolated mouse jejunum muscle strips induced by ghrelin (Item Nos. 15072 | 24458). In vivo, obestatin (12.5-1,000 nmol/kg) suppresses food intake in a time- and dose-dependent manner and reduces body weight gain and gastric emptying in mice. Obestatin (0.22 g per animal) also reduces food intake and glucose response without affecting plasma insulin responses in fasted high-fat diet fed mice.{38829}
Brand:CaymanSKU:24552 - 500 µgAvailable on backorder
Obscurolide A1 is a natural butyrolactone isolated from S. viridochromogenes.{22551} It inhibits calcium/calmodulin-dependent phosphodiesterase from bovine brain, presumably PDE1 (IC50 = 15 mM).{22551}
Brand:CaymanSKU:-Obscurolide A1 is a natural butyrolactone isolated from S. viridochromogenes.{22551} It inhibits calcium/calmodulin-dependent phosphodiesterase from bovine brain, presumably PDE1 (IC50 = 15 mM).{22551}
Brand:CaymanSKU:-OC000459 is a potent, selective DP2 antagonist that displaces [3H]prostaglandin D2 ([3H]PGD2) from human recombinant DP2 receptors (Ki = 13 nM), rat recombinant DP2 receptors (Ki = 3 nM), and human native DP2 (Ki = 4 nM; Th2 cell membranes) without interfering with the ligand binding properties of other prostanoid receptors, including PGE1–4, DP1, TP, PGI2, and PGF.{22642} OC000459 inhibits chemotaxis and cytokine production of human Th2 lymphocytes with IC50 values of 28 and 19 nM, respectively, and competitively antagonizes eosinophil shape change responses induced by PGD2 in both isolated human leukocytes (pKB = 7.9) and human whole blood (pKB = 7.5).{22642} OC000459 was shown to inhibit blood eosinophilia in rats induced by 13,14-dihydro-15-keto PGD2 (Item No. 12610) (ED50 = 0.04 mg/kg) and airway eosinophilia in guinea pigs in response to an aerosol of 13,14-dihydro-15-keto PGD2 (ED50 = 0.01 mg/kg).{22642}
Brand:CaymanSKU:12027 - 10 mgAvailable on backorder
OC000459 is a potent, selective DP2 antagonist that displaces [3H]prostaglandin D2 ([3H]PGD2) from human recombinant DP2 receptors (Ki = 13 nM), rat recombinant DP2 receptors (Ki = 3 nM), and human native DP2 (Ki = 4 nM; Th2 cell membranes) without interfering with the ligand binding properties of other prostanoid receptors, including PGE1–4, DP1, TP, PGI2, and PGF.{22642} OC000459 inhibits chemotaxis and cytokine production of human Th2 lymphocytes with IC50 values of 28 and 19 nM, respectively, and competitively antagonizes eosinophil shape change responses induced by PGD2 in both isolated human leukocytes (pKB = 7.9) and human whole blood (pKB = 7.5).{22642} OC000459 was shown to inhibit blood eosinophilia in rats induced by 13,14-dihydro-15-keto PGD2 (Item No. 12610) (ED50 = 0.04 mg/kg) and airway eosinophilia in guinea pigs in response to an aerosol of 13,14-dihydro-15-keto PGD2 (ED50 = 0.01 mg/kg).{22642}
Brand:CaymanSKU:12027 - 25 mgAvailable on backorder
OC000459 is a potent, selective DP2 antagonist that displaces [3H]prostaglandin D2 ([3H]PGD2) from human recombinant DP2 receptors (Ki = 13 nM), rat recombinant DP2 receptors (Ki = 3 nM), and human native DP2 (Ki = 4 nM; Th2 cell membranes) without interfering with the ligand binding properties of other prostanoid receptors, including PGE1–4, DP1, TP, PGI2, and PGF.{22642} OC000459 inhibits chemotaxis and cytokine production of human Th2 lymphocytes with IC50 values of 28 and 19 nM, respectively, and competitively antagonizes eosinophil shape change responses induced by PGD2 in both isolated human leukocytes (pKB = 7.9) and human whole blood (pKB = 7.5).{22642} OC000459 was shown to inhibit blood eosinophilia in rats induced by 13,14-dihydro-15-keto PGD2 (Item No. 12610) (ED50 = 0.04 mg/kg) and airway eosinophilia in guinea pigs in response to an aerosol of 13,14-dihydro-15-keto PGD2 (ED50 = 0.01 mg/kg).{22642}
Brand:CaymanSKU:12027 - 5 mgAvailable on backorder
Ochratoxin A (OTA) is a mycotoxin that has been found in Aspergillus and Penicillium.{21687} It increases lipid peroxide levels and the number of apoptotic cells, as well as reduces superoxide dismutase activity in rat kidney when administered at a dose of 120 μg/kg.{57301} Topical application of ochratoxin A (80 μg/mouse) induces DNA damage, cell cycle arrest at the G0/G1 phase, and apoptosis in mouse skin cells.{21687} It also initiates tumor formation in a two-stage mouse skin tumorigenesis model. Ochratoxin A has been found as a contaminant in a variety of foods.{21686}
Brand:CaymanSKU:11439 - 1 mgAvailable on backorder
Ochratoxin A (OTA) is a mycotoxin that has been found in Aspergillus and Penicillium.{21687} It increases lipid peroxide levels and the number of apoptotic cells, as well as reduces superoxide dismutase activity in rat kidney when administered at a dose of 120 μg/kg.{57301} Topical application of ochratoxin A (80 μg/mouse) induces DNA damage, cell cycle arrest at the G0/G1 phase, and apoptosis in mouse skin cells.{21687} It also initiates tumor formation in a two-stage mouse skin tumorigenesis model. Ochratoxin A has been found as a contaminant in a variety of foods.{21686}
Brand:CaymanSKU:11439 - 10 mgAvailable on backorder
Ochratoxin A (OTA) is a mycotoxin that has been found in Aspergillus and Penicillium.{21687} It increases lipid peroxide levels and the number of apoptotic cells, as well as reduces superoxide dismutase activity in rat kidney when administered at a dose of 120 μg/kg.{57301} Topical application of ochratoxin A (80 μg/mouse) induces DNA damage, cell cycle arrest at the G0/G1 phase, and apoptosis in mouse skin cells.{21687} It also initiates tumor formation in a two-stage mouse skin tumorigenesis model. Ochratoxin A has been found as a contaminant in a variety of foods.{21686}
Brand:CaymanSKU:11439 - 5 mgAvailable on backorder
Ochratoxin A-13C20 is intended for use as an internal standard for the quantification of ochratoxin A (Item No. 11439) by GC- or LC-MS. Ochratoxin A is a mycotoxin that has been found in Aspergillus and Penicillium.{21687} It increases lipid peroxide levels and the number of apoptotic cells, as well as reduces superoxide dismutase activity in rat kidney when administered at a dose of 120 μg/kg.{57301} Topical application of ochratoxin A (80 μg/mouse) induces DNA damage, cell cycle arrest at the G0/G1 phase, and apoptosis in mouse skin cells.{21687} It also initiates tumor formation in a two-stage mouse skin tumorigenesis model. Ochratoxin A has been found as a contaminant in a variety of foods.{21686}
Brand:CaymanSKU:31295 - 1.2 mlAvailable on backorder
Ochratoxins are mycotoxins produced by Aspergillus and Penicillium species of fungi that contaminate foods.{20560,20493} Ochratoxin A (OTA, Item No. 11439) is a chlorinated form with toxicity that targets the kidneys, causing nephropathy and renal adenomas.{20560,20493} OTB is a non-chlorinated analog of OTA that has cytotoxic effects on kidney and liver cells in vitro but only minor effects in vivo, due to its rapid metabolism and excretion.{26426,26425,26424} OTB inhibits cell proliferation of human liver HepG2 cells at doses as low as 1 µg/ml but lacks the genotoxic activity of OTA, even at higher concentrations.{26426}
Brand:CaymanSKU:-Ochratoxins are mycotoxins produced by Aspergillus and Penicillium species of fungi that contaminate foods.{20560,20493} Ochratoxin A (OTA, Item No. 11439) is a chlorinated form with toxicity that targets the kidneys, causing nephropathy and renal adenomas.{20560,20493} OTB is a non-chlorinated analog of OTA that has cytotoxic effects on kidney and liver cells in vitro but only minor effects in vivo, due to its rapid metabolism and excretion.{26426,26425,26424} OTB inhibits cell proliferation of human liver HepG2 cells at doses as low as 1 µg/ml but lacks the genotoxic activity of OTA, even at higher concentrations.{26426}
Brand:CaymanSKU:-Ochratoxins are mycotoxins produced by Aspergillus and Penicillium species of fungi that contaminate foods.{20560,20493} Ochratoxin A (OTA, Item No. 11439) is a chlorinated form with toxicity that targets the kidneys, causing nephropathy and renal adenomas.{20560,20493} OTB is a non-chlorinated analog of OTA that has cytotoxic effects on kidney and liver cells in vitro but only minor effects in vivo, due to its rapid metabolism and excretion.{26426,26425,26424} OTB inhibits cell proliferation of human liver HepG2 cells at doses as low as 1 µg/ml but lacks the genotoxic activity of OTA, even at higher concentrations.{26426}
Brand:CaymanSKU:-Ochratoxin C is the ethyl ester analog of ochratoxin A (Item No. 11439), a mycotoxin produced by A. ochraceus, A. carbonarius, and P. verrucosum that is commonly found as a food contaminant. Ochratoxin C rarely occurs as an initial natural contaminant. Instead, its presence as a food contaminant usually occurs due to a transformation from ochratoxin A.{31745}
Brand:CaymanSKU:20183 -Available on backorder
Ochratoxin C is the ethyl ester analog of ochratoxin A (Item No. 11439), a mycotoxin produced by A. ochraceus, A. carbonarius, and P. verrucosum that is commonly found as a food contaminant. Ochratoxin C rarely occurs as an initial natural contaminant. Instead, its presence as a food contaminant usually occurs due to a transformation from ochratoxin A.{31745}
Brand:CaymanSKU:20183 -Available on backorder
Oclacitinib is an inhibitor of the JAK family kinases JAK1, JAK2, JAK3, and TYK2 (IC50s = 10, 18, 99, and 84 nM, respectively).{30396} It is selective for JAK kinases over a panel of 38 additional kinases at 1 μM. Oclacitinib inhibits LPS-induced increases in IL-12 and TNF-α levels in murine bone marrow-derived dendritic cells (BMDCs) in a concentration-dependent manner.{48761} Topical administration of oclacitinib (0.1, 0.25, and 0.5%) reduces scratching behavior and ear edema, as well as decreases levels of IL-1β, IL-4, and IL-6 in ear skin, in a mouse model of allergic dermatitis induced by toluene-2,3-diisocyanate (TDI). Formulations containing oclacitinib have been used in the treatment of pruritus associated with allergic dermatitis and the control of atopic dermatitis in dogs.
Brand:CaymanSKU:-Available on backorder
Oclacitinib is an inhibitor of the JAK family kinases JAK1, JAK2, JAK3, and TYK2 (IC50s = 10, 18, 99, and 84 nM, respectively).{30396} It is selective for JAK kinases over a panel of 38 additional kinases at 1 μM. Oclacitinib inhibits LPS-induced increases in IL-12 and TNF-α levels in murine bone marrow-derived dendritic cells (BMDCs) in a concentration-dependent manner.{48761} Topical administration of oclacitinib (0.1, 0.25, and 0.5%) reduces scratching behavior and ear edema, as well as decreases levels of IL-1β, IL-4, and IL-6 in ear skin, in a mouse model of allergic dermatitis induced by toluene-2,3-diisocyanate (TDI). Formulations containing oclacitinib have been used in the treatment of pruritus associated with allergic dermatitis and the control of atopic dermatitis in dogs.
Brand:CaymanSKU:-Available on backorder
Oclacitinib is an inhibitor of the JAK family kinases JAK1, JAK2, JAK3, and TYK2 (IC50s = 10, 18, 99, and 84 nM, respectively).{30396} It is selective for JAK kinases over a panel of 38 additional kinases at 1 μM. Oclacitinib inhibits LPS-induced increases in IL-12 and TNF-α levels in murine bone marrow-derived dendritic cells (BMDCs) in a concentration-dependent manner.{48761} Topical administration of oclacitinib (0.1, 0.25, and 0.5%) reduces scratching behavior and ear edema, as well as decreases levels of IL-1β, IL-4, and IL-6 in ear skin, in a mouse model of allergic dermatitis induced by toluene-2,3-diisocyanate (TDI). Formulations containing oclacitinib have been used in the treatment of pruritus associated with allergic dermatitis and the control of atopic dermatitis in dogs.
Brand:CaymanSKU:-Available on backorder
Oclacitinib is an inhibitor of the JAK family kinases JAK1, JAK2, JAK3, and TYK2 (IC50s = 10, 18, 99, and 84 nM, respectively).{30396} It is selective for JAK kinases over a panel of 38 additional kinases at 1 μM. Oclacitinib inhibits LPS-induced increases in IL-12 and TNF-α levels in murine bone marrow-derived dendritic cells (BMDCs) in a concentration-dependent manner.{48761} Topical administration of oclacitinib (0.1, 0.25, and 0.5%) reduces scratching behavior and ear edema, as well as decreases levels of IL-1β, IL-4, and IL-6 in ear skin, in a mouse model of allergic dermatitis induced by toluene-2,3-diisocyanate (TDI). Formulations containing oclacitinib have been used in the treatment of pruritus associated with allergic dermatitis and the control of atopic dermatitis in dogs.
Brand:CaymanSKU:-Available on backorder
Octacosanoic acid is a very long-chain saturated fatty acid. It is the major component of D-003, a mixture of very long-chain aliphatic acids purified from sugar cane wax that has antiplatelet and cholesterol-lowering activities in animal models.{54532}
Brand:CaymanSKU:31735 - 1 gAvailable on backorder
Octacosanoic acid is a very long-chain saturated fatty acid. It is the major component of D-003, a mixture of very long-chain aliphatic acids purified from sugar cane wax that has antiplatelet and cholesterol-lowering activities in animal models.{54532}
Brand:CaymanSKU:31735 - 100 mgAvailable on backorder
Octacosanoic acid is a very long-chain saturated fatty acid. It is the major component of D-003, a mixture of very long-chain aliphatic acids purified from sugar cane wax that has antiplatelet and cholesterol-lowering activities in animal models.{54532}
Brand:CaymanSKU:31735 - 250 mgAvailable on backorder
Octacosanoic acid is a very long-chain saturated fatty acid. It is the major component of D-003, a mixture of very long-chain aliphatic acids purified from sugar cane wax that has antiplatelet and cholesterol-lowering activities in animal models.{54532}
Brand:CaymanSKU:31735 - 500 mgAvailable on backorder
Octacosanoic acid methyl ester is a very long-chain fatty acid methyl ester that has been found in transesterified palm oil.{46212} It has also been found in biodiesel produced by the microalga Botryococcus and in sediment samples from Lake Kivu in the East African rift valley.{46213,38863} [Matreya, LLC. Catalog No. 1271]
Brand:CaymanSKU:26726 - 10 mgAvailable on backorder
Octacosanoic acid methyl ester is a very long-chain fatty acid methyl ester that has been found in transesterified palm oil.{46212} It has also been found in biodiesel produced by the microalga Botryococcus and in sediment samples from Lake Kivu in the East African rift valley.{46213,38863} [Matreya, LLC. Catalog No. 1271]
Brand:CaymanSKU:26726 - 100 mgAvailable on backorder
Octacosanoic acid methyl ester is a very long-chain fatty acid methyl ester that has been found in transesterified palm oil.{46212} It has also been found in biodiesel produced by the microalga Botryococcus and in sediment samples from Lake Kivu in the East African rift valley.{46213,38863} [Matreya, LLC. Catalog No. 1271]
Brand:CaymanSKU:26726 - 5 mgAvailable on backorder
Octacosanoic acid methyl ester is a very long-chain fatty acid methyl ester that has been found in transesterified palm oil.{46212} It has also been found in biodiesel produced by the microalga Botryococcus and in sediment samples from Lake Kivu in the East African rift valley.{46213,38863} [Matreya, LLC. Catalog No. 1271]
Brand:CaymanSKU:26726 - 50 mgAvailable on backorder
Octanoic acid methyl ester is a fatty acid methyl ester that has been found in biodiesels made from the transesterification of beef tallow, soybean oil, and babassu oil blends.{48265} It is an aromatic volatile compound in cantaloupe, galia, and honeydew melons.{48266}
Brand:CaymanSKU:26717 - 100 gAvailable on backorder
Octanoic acid methyl ester is a fatty acid methyl ester that has been found in biodiesels made from the transesterification of beef tallow, soybean oil, and babassu oil blends.{48265} It is an aromatic volatile compound in cantaloupe, galia, and honeydew melons.{48266}
Brand:CaymanSKU:26717 - 250 gAvailable on backorder
Octanoic acid methyl ester is a fatty acid methyl ester that has been found in biodiesels made from the transesterification of beef tallow, soybean oil, and babassu oil blends.{48265} It is an aromatic volatile compound in cantaloupe, galia, and honeydew melons.{48266}
Brand:CaymanSKU:26717 - 50 gAvailable on backorder
Octanoic acid methyl ester is a fatty acid methyl ester that has been found in biodiesels made from the transesterification of beef tallow, soybean oil, and babassu oil blends.{48265} It is an aromatic volatile compound in cantaloupe, galia, and honeydew melons.{48266}
Brand:CaymanSKU:26717 - 500 gAvailable on backorder
Octanoic acid-13C is intended for use as an internal standard for the quantification of octanoic acid by GC- or LC-MS. Octanoic acid is a medium-chain saturated fatty acid. It has been found in Teleme cheeses made from goat, ovine, or bovine milk.{45567} Octanoic acid is active against the bacteria S. mutans, S. gordonii, F. nucleatum, and P. gingivalis (IC80s = <125, <125, 1,403, and 2,294 μM, respectively).{45568} Levels of octanoic acid are increased in the plasma of patients with medium-chain acyl-CoA dehydrogenase (MCAD) deficiency, an inborn error of fatty acid metabolism characterized by hypoketotic hypoglycemia, medium-chain dicarboxylic aciduria, and intolerance to fasting.{40631,26849}
Brand:CaymanSKU:29461 - 250 mgAvailable on backorder
Octanoic acid-13C is intended for use as an internal standard for the quantification of octanoic acid by GC- or LC-MS. Octanoic acid is a medium-chain saturated fatty acid. It has been found in Teleme cheeses made from goat, ovine, or bovine milk.{45567} Octanoic acid is active against the bacteria S. mutans, S. gordonii, F. nucleatum, and P. gingivalis (IC80s = <125, <125, 1,403, and 2,294 μM, respectively).{45568} Levels of octanoic acid are increased in the plasma of patients with medium-chain acyl-CoA dehydrogenase (MCAD) deficiency, an inborn error of fatty acid metabolism characterized by hypoketotic hypoglycemia, medium-chain dicarboxylic aciduria, and intolerance to fasting.{40631,26849}
Brand:CaymanSKU:29461 - 500 mgAvailable on backorder
Octanoic acid-d15 is intended for use as an internal standard for the quantification of octanoic acid by GC- or LC-MS. Octanoic acid is a medium-chain saturated fatty acid. It has been found in Teleme cheeses made from goat, ovine, or bovine milk.{45567} Octanoic acid is active against the bacteria S. mutans, S. gordonii, F. nucleatum, and P. gingivalis (IC80s = <125, <125, 1,403, and 2,294 μM, respectively).{45568} Levels of octanoic acid are increased in the plasma of patients with medium-chain acyl-CoA dehydrogenase (MCAD) deficiency, an inborn error of fatty acid metabolism characterized by hypoketotic hypoglycemia, medium-chain dicarboxylic aciduria, and intolerance to fasting.{40631,26849}
Brand:CaymanSKU:29074 - 100 mgAvailable on backorder
Octanoic acid-d15 is intended for use as an internal standard for the quantification of octanoic acid by GC- or LC-MS. Octanoic acid is a medium-chain saturated fatty acid. It has been found in Teleme cheeses made from goat, ovine, or bovine milk.{45567} Octanoic acid is active against the bacteria S. mutans, S. gordonii, F. nucleatum, and P. gingivalis (IC80s = <125, <125, 1,403, and 2,294 μM, respectively).{45568} Levels of octanoic acid are increased in the plasma of patients with medium-chain acyl-CoA dehydrogenase (MCAD) deficiency, an inborn error of fatty acid metabolism characterized by hypoketotic hypoglycemia, medium-chain dicarboxylic aciduria, and intolerance to fasting.{40631,26849}
Brand:CaymanSKU:29074 - 25 mgAvailable on backorder
Octanoic acid-d15 is intended for use as an internal standard for the quantification of octanoic acid by GC- or LC-MS. Octanoic acid is a medium-chain saturated fatty acid. It has been found in Teleme cheeses made from goat, ovine, or bovine milk.{45567} Octanoic acid is active against the bacteria S. mutans, S. gordonii, F. nucleatum, and P. gingivalis (IC80s = <125, <125, 1,403, and 2,294 μM, respectively).{45568} Levels of octanoic acid are increased in the plasma of patients with medium-chain acyl-CoA dehydrogenase (MCAD) deficiency, an inborn error of fatty acid metabolism characterized by hypoketotic hypoglycemia, medium-chain dicarboxylic aciduria, and intolerance to fasting.{40631,26849}
Brand:CaymanSKU:29074 - 250 mgAvailable on backorder
Octanoic acid-d15 is intended for use as an internal standard for the quantification of octanoic acid by GC- or LC-MS. Octanoic acid is a medium-chain saturated fatty acid. It has been found in Teleme cheeses made from goat, ovine, or bovine milk.{45567} Octanoic acid is active against the bacteria S. mutans, S. gordonii, F. nucleatum, and P. gingivalis (IC80s = <125, <125, 1,403, and 2,294 μM, respectively).{45568} Levels of octanoic acid are increased in the plasma of patients with medium-chain acyl-CoA dehydrogenase (MCAD) deficiency, an inborn error of fatty acid metabolism characterized by hypoketotic hypoglycemia, medium-chain dicarboxylic aciduria, and intolerance to fasting.{40631,26849}
Brand:CaymanSKU:29074 - 50 mgAvailable on backorder
Octanoic acid-d2 is intended for use as an internal standard for the quantification of octanoic acid by GC- or LC-MS. Octanoic acid is a medium-chain saturated fatty acid. It has been found in Teleme cheeses made from goat, ovine, or bovine milk.{45567} Octanoic acid is active against the bacteria S. mutans, S. gordonii, F. nucleatum, and P. gingivalis (IC80s = <125, <125, 1,403, and 2,294 μM, respectively).{45568} Levels of octanoic acid are increased in the plasma of patients with medium-chain acyl-CoA dehydrogenase (MCAD) deficiency, an inborn error of fatty acid metabolism characterized by hypoketotic hypoglycemia, medium-chain dicarboxylic aciduria, and intolerance to fasting.{40631,26849}
Brand:CaymanSKU:29412 - 1 mgAvailable on backorder
Octanoic acid-d2 is intended for use as an internal standard for the quantification of octanoic acid by GC- or LC-MS. Octanoic acid is a medium-chain saturated fatty acid. It has been found in Teleme cheeses made from goat, ovine, or bovine milk.{45567} Octanoic acid is active against the bacteria S. mutans, S. gordonii, F. nucleatum, and P. gingivalis (IC80s = <125, <125, 1,403, and 2,294 μM, respectively).{45568} Levels of octanoic acid are increased in the plasma of patients with medium-chain acyl-CoA dehydrogenase (MCAD) deficiency, an inborn error of fatty acid metabolism characterized by hypoketotic hypoglycemia, medium-chain dicarboxylic aciduria, and intolerance to fasting.{40631,26849}
Brand:CaymanSKU:29412 - 10 mgAvailable on backorder
Octanoic acid-d2 is intended for use as an internal standard for the quantification of octanoic acid by GC- or LC-MS. Octanoic acid is a medium-chain saturated fatty acid. It has been found in Teleme cheeses made from goat, ovine, or bovine milk.{45567} Octanoic acid is active against the bacteria S. mutans, S. gordonii, F. nucleatum, and P. gingivalis (IC80s = <125, <125, 1,403, and 2,294 μM, respectively).{45568} Levels of octanoic acid are increased in the plasma of patients with medium-chain acyl-CoA dehydrogenase (MCAD) deficiency, an inborn error of fatty acid metabolism characterized by hypoketotic hypoglycemia, medium-chain dicarboxylic aciduria, and intolerance to fasting.{40631,26849}
Brand:CaymanSKU:29412 - 100 mgAvailable on backorder
Octanoic acid-d2 is intended for use as an internal standard for the quantification of octanoic acid by GC- or LC-MS. Octanoic acid is a medium-chain saturated fatty acid. It has been found in Teleme cheeses made from goat, ovine, or bovine milk.{45567} Octanoic acid is active against the bacteria S. mutans, S. gordonii, F. nucleatum, and P. gingivalis (IC80s = <125, <125, 1,403, and 2,294 μM, respectively).{45568} Levels of octanoic acid are increased in the plasma of patients with medium-chain acyl-CoA dehydrogenase (MCAD) deficiency, an inborn error of fatty acid metabolism characterized by hypoketotic hypoglycemia, medium-chain dicarboxylic aciduria, and intolerance to fasting.{40631,26849}
Brand:CaymanSKU:29412 - 5 mgAvailable on backorder
Octanoic acid-d3 is intended for use as an internal standard for the quantification of octanoic acid by GC- or LC-MS. Octanoic acid is a medium-chain saturated fatty acid. It has been found in Teleme cheeses made from goat, ovine, or bovine milk.{45567} Octanoic acid is active against the bacteria S. mutans, S. gordonii, F. nucleatum, and P. gingivalis (IC80s = <125, <125, 1,403, and 2,294 μM, respectively).{45568} Levels of octanoic acid are increased in the plasma of patients with medium-chain acyl-CoA dehydrogenase (MCAD) deficiency, an inborn error of fatty acid metabolism characterized by hypoketotic hypoglycemia, medium-chain dicarboxylic aciduria, and intolerance to fasting.{40631,26849}
Brand:CaymanSKU:28869 - 1 mgAvailable on backorder
Octanoic acid-d3 is intended for use as an internal standard for the quantification of octanoic acid by GC- or LC-MS. Octanoic acid is a medium-chain saturated fatty acid. It has been found in Teleme cheeses made from goat, ovine, or bovine milk.{45567} Octanoic acid is active against the bacteria S. mutans, S. gordonii, F. nucleatum, and P. gingivalis (IC80s = <125, <125, 1,403, and 2,294 μM, respectively).{45568} Levels of octanoic acid are increased in the plasma of patients with medium-chain acyl-CoA dehydrogenase (MCAD) deficiency, an inborn error of fatty acid metabolism characterized by hypoketotic hypoglycemia, medium-chain dicarboxylic aciduria, and intolerance to fasting.{40631,26849}
Brand:CaymanSKU:28869 - 10 mgAvailable on backorder
Octanoic acid-d3 is intended for use as an internal standard for the quantification of octanoic acid by GC- or LC-MS. Octanoic acid is a medium-chain saturated fatty acid. It has been found in Teleme cheeses made from goat, ovine, or bovine milk.{45567} Octanoic acid is active against the bacteria S. mutans, S. gordonii, F. nucleatum, and P. gingivalis (IC80s = <125, <125, 1,403, and 2,294 μM, respectively).{45568} Levels of octanoic acid are increased in the plasma of patients with medium-chain acyl-CoA dehydrogenase (MCAD) deficiency, an inborn error of fatty acid metabolism characterized by hypoketotic hypoglycemia, medium-chain dicarboxylic aciduria, and intolerance to fasting.{40631,26849}
Brand:CaymanSKU:28869 - 25 mgAvailable on backorder
Octanoic acid-d3 is intended for use as an internal standard for the quantification of octanoic acid by GC- or LC-MS. Octanoic acid is a medium-chain saturated fatty acid. It has been found in Teleme cheeses made from goat, ovine, or bovine milk.{45567} Octanoic acid is active against the bacteria S. mutans, S. gordonii, F. nucleatum, and P. gingivalis (IC80s = <125, <125, 1,403, and 2,294 μM, respectively).{45568} Levels of octanoic acid are increased in the plasma of patients with medium-chain acyl-CoA dehydrogenase (MCAD) deficiency, an inborn error of fatty acid metabolism characterized by hypoketotic hypoglycemia, medium-chain dicarboxylic aciduria, and intolerance to fasting.{40631,26849}
Brand:CaymanSKU:28869 - 5 mgAvailable on backorder
Octanoyl-DL-carnitine is a medium-chain acylcarnitine. It decreases the oxidation rate of the branched-chain 2-oxo acids 3-methyl-2-butanoate and 4-methyl-2-oxopentanoate in isolated rat muscle mitochondria in the presence of carnitine, but increases it in the absence of carnitine.{55274} Octanoyl-DL-carnitine, with malate, has been used as a mitochondrial respiration substrate to measure the effect of creatine on the respiration rate of isolated rat cardiac fibers exposed to increasing concentrations of ADP.{55275}
Brand:CaymanSKU:-Octanoyl-DL-carnitine is a medium-chain acylcarnitine. It decreases the oxidation rate of the branched-chain 2-oxo acids 3-methyl-2-butanoate and 4-methyl-2-oxopentanoate in isolated rat muscle mitochondria in the presence of carnitine, but increases it in the absence of carnitine.{55274} Octanoyl-DL-carnitine, with malate, has been used as a mitochondrial respiration substrate to measure the effect of creatine on the respiration rate of isolated rat cardiac fibers exposed to increasing concentrations of ADP.{55275}
Brand:CaymanSKU:-Octanoyl-DL-carnitine is a medium-chain acylcarnitine. It decreases the oxidation rate of the branched-chain 2-oxo acids 3-methyl-2-butanoate and 4-methyl-2-oxopentanoate in isolated rat muscle mitochondria in the presence of carnitine, but increases it in the absence of carnitine.{55274} Octanoyl-DL-carnitine, with malate, has been used as a mitochondrial respiration substrate to measure the effect of creatine on the respiration rate of isolated rat cardiac fibers exposed to increasing concentrations of ADP.{55275}
Brand:CaymanSKU:-Octanoyl-L-carnitine is a medium-chain acylcarnitine and the physiologically active form of octanoyl-DL-carnitine (Item No. 15048).{47123} Plasma levels of octanoyl-L-carnitine are elevated in patients with end-stage renal disease on continuous ambulatory peritoneal dialysis (PD) compared with both patients on automated PD and healthy individuals.{47277} Octanoyl-L-carnitine does not undergo hydrolysis in the blood or during sample preparation when used as a standard for the quantification of octanoylcarnitine.{47123}
Brand:CaymanSKU:26558 - 10 mgAvailable on backorder
Octanoyl-L-carnitine is a medium-chain acylcarnitine and the physiologically active form of octanoyl-DL-carnitine (Item No. 15048).{47123} Plasma levels of octanoyl-L-carnitine are elevated in patients with end-stage renal disease on continuous ambulatory peritoneal dialysis (PD) compared with both patients on automated PD and healthy individuals.{47277} Octanoyl-L-carnitine does not undergo hydrolysis in the blood or during sample preparation when used as a standard for the quantification of octanoylcarnitine.{47123}
Brand:CaymanSKU:26558 - 5 mgAvailable on backorder
Octanoyl-L-carnitine is a medium-chain acylcarnitine and the physiologically active form of octanoyl-DL-carnitine (Item No. 15048).{47123} Plasma levels of octanoyl-L-carnitine are elevated in patients with end-stage renal disease on continuous ambulatory peritoneal dialysis (PD) compared with both patients on automated PD and healthy individuals.{47277} Octanoyl-L-carnitine does not undergo hydrolysis in the blood or during sample preparation when used as a standard for the quantification of octanoylcarnitine.{47123}
Brand:CaymanSKU:26558 - 50 mgAvailable on backorder
Octanoyl-L-carnitine-d3 is intended for use as an internal standard for the quantification of octanoyl-L-carnitine (Item No. 26558) by GC- or LC-MS. Octanoyl-L-carnitine is a medium-chain acylcarnitine and the physiologically active form of octanoyl-DL-carnitine (Item No. 15048).{47123} Plasma levels of octanoyl-L-carnitine are elevated in patients with end-stage renal disease on continuous ambulatory peritoneal dialysis (PD) compared with both patients on automated PD and healthy individuals.{47277} Octanoyl-L-carnitine does not undergo hydrolysis in the blood or during sample preparation when used as a standard for the quantification of octanoylcarnitine.{47123}
Brand:CaymanSKU:26577 - 1 mgAvailable on backorder