Chemicals

Showing 27901–28050 of 41137 results

  • Myricetrin is a flavonoid that has been found in C. menyharthii leaf extracts and has diverse biological activities.{47426,47427} It is active against B. subtilis, E. coli, K. pneumoniae, S. aureus, and C. albicans (MIC = 0.25 mg/ml for all).{47426} Myricetrin inhibits acetylcholinesterase (AChE) and α-glucosidase in vitro (IC50s = 65 and 79 μg/ml, respectively). It inhibits LPS-induced production of TNF-α and enhances LPS-induced RANTES production in RAW 264.7 cells when used at concentrations of 0.2 and 1 mM.{47427}  

     

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    Cayman
    SKU:26902 - 50 mg

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  • Myriocin is an amino fatty acid antibiotic derived from certain thermophylic fungi, in this case Mycelia sterilia. It is a potent immunosuppressant having 10- to 100-fold more activity than cyclosporin A.{8482} Myriocin is a potent inhibitor of serine palmitoyltransferase (Ki = 0.28 nM), the enzyme that catalyzes the first step of sphingolipid biosynthesis. {14764} It disrupts substratum adhesion of melanoma cells.{14763} It also suppresses cell proliferation in the murine cytotoxic T cell line CTLL-2 (IC50 = 15 nM) via apoptosis.{14764,2816} Myriocin suppresses replication of the hepatitis C virus in a murine model.{14762}  

     

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    SKU:63150 - 1 mg

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  • Myriocin is an amino fatty acid antibiotic derived from certain thermophylic fungi, in this case Mycelia sterilia. It is a potent immunosuppressant having 10- to 100-fold more activity than cyclosporin A.{8482} Myriocin is a potent inhibitor of serine palmitoyltransferase (Ki = 0.28 nM), the enzyme that catalyzes the first step of sphingolipid biosynthesis. {14764} It disrupts substratum adhesion of melanoma cells.{14763} It also suppresses cell proliferation in the murine cytotoxic T cell line CTLL-2 (IC50 = 15 nM) via apoptosis.{14764,2816} Myriocin suppresses replication of the hepatitis C virus in a murine model.{14762}  

     

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    SKU:63150 - 10 mg

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  • Myriocin is an amino fatty acid antibiotic derived from certain thermophylic fungi, in this case Mycelia sterilia. It is a potent immunosuppressant having 10- to 100-fold more activity than cyclosporin A.{8482} Myriocin is a potent inhibitor of serine palmitoyltransferase (Ki = 0.28 nM), the enzyme that catalyzes the first step of sphingolipid biosynthesis. {14764} It disrupts substratum adhesion of melanoma cells.{14763} It also suppresses cell proliferation in the murine cytotoxic T cell line CTLL-2 (IC50 = 15 nM) via apoptosis.{14764,2816} Myriocin suppresses replication of the hepatitis C virus in a murine model.{14762}  

     

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    Cayman
    SKU:63150 - 25 mg

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  • Myriocin is an amino fatty acid antibiotic derived from certain thermophylic fungi, in this case Mycelia sterilia. It is a potent immunosuppressant having 10- to 100-fold more activity than cyclosporin A.{8482} Myriocin is a potent inhibitor of serine palmitoyltransferase (Ki = 0.28 nM), the enzyme that catalyzes the first step of sphingolipid biosynthesis. {14764} It disrupts substratum adhesion of melanoma cells.{14763} It also suppresses cell proliferation in the murine cytotoxic T cell line CTLL-2 (IC50 = 15 nM) via apoptosis.{14764,2816} Myriocin suppresses replication of the hepatitis C virus in a murine model.{14762}  

     

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    SKU:63150 - 5 mg

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  • Myristelaidic acid is a 14-carbon monounsaturated ω-5 long-chain fatty acid. It is the trans isomer of myristoleic acid (Item No. 9002461). Myristelaidic acid is converted to myristelaidoyl CoA at a faster rate than myristoleic acid to myristoleoyl CoA.{36190}  

     

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    SKU:22361 -

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  • Myristelaidic acid is a 14-carbon monounsaturated ω-5 long-chain fatty acid. It is the trans isomer of myristoleic acid (Item No. 9002461). Myristelaidic acid is converted to myristelaidoyl CoA at a faster rate than myristoleic acid to myristoleoyl CoA.{36190}  

     

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  • Myristelaidic acid is a 14-carbon monounsaturated ω-5 long-chain fatty acid. It is the trans isomer of myristoleic acid (Item No. 9002461). Myristelaidic acid is converted to myristelaidoyl CoA at a faster rate than myristoleic acid to myristoleoyl CoA.{36190}  

     

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  • Myristelaidic acid is a 14-carbon monounsaturated ω-5 long-chain fatty acid. It is the trans isomer of myristoleic acid (Item No. 9002461). Myristelaidic acid is converted to myristelaidoyl CoA at a faster rate than myristoleic acid to myristoleoyl CoA.{36190}  

     

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    SKU:22361 -

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  • Myristic acid is a 14-carbon saturated fatty acid. It is incorporated into myristoyl coenzyme A (myristoyl-CoA) and transferred by N-myristoyltransferase to the N-terminal glycine of certain proteins either during translation to modify protein activity or post-translationally in apoptotic cells.{41877,41878}  

     

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  • Myristic acid is a 14-carbon saturated fatty acid. It is incorporated into myristoyl coenzyme A (myristoyl-CoA) and transferred by N-myristoyltransferase to the N-terminal glycine of certain proteins either during translation to modify protein activity or post-translationally in apoptotic cells.{41877,41878}  

     

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  • Myristic acid is a 14-carbon saturated fatty acid. It is incorporated into myristoyl coenzyme A (myristoyl-CoA) and transferred by N-myristoyltransferase to the N-terminal glycine of certain proteins either during translation to modify protein activity or post-translationally in apoptotic cells.{41877,41878}  

     

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  • Myristic acid is a 14-carbon saturated (14:0) fatty acid. In vivo, it is commonly added covalently to the N-terminus of proteins in a co-translational process termed N-myristoylation.{17231} The sirtuin SIRT6 removes this acyl group from myristoylated TNF-α, enhancing secretion.{22694} Myristic acid alkyne is a form of this myristic acid (Item No. 13351) with an ω-terminal alkyne. Such terminal alkyne groups can be used in linking reactions, known as click chemistry, characterized by high dependability and specificity of azide-alkyne bioconjugation reactions.{17991,17992} Click chemistry has only recently been applied to the study of lipids.{22694,16188}  

     

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  • Myristic acid is a 14-carbon saturated (14:0) fatty acid. In vivo, it is commonly added covalently to the N-terminus of proteins in a co-translational process termed N-myristoylation.{17231} The sirtuin SIRT6 removes this acyl group from myristoylated TNF-α, enhancing secretion.{22694} Myristic acid alkyne is a form of this myristic acid (Item No. 13351) with an ω-terminal alkyne. Such terminal alkyne groups can be used in linking reactions, known as click chemistry, characterized by high dependability and specificity of azide-alkyne bioconjugation reactions.{17991,17992} Click chemistry has only recently been applied to the study of lipids.{22694,16188}  

     

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  • Myristic acid is a 14-carbon saturated (14:0) fatty acid. In vivo, it is commonly added covalently to the N-terminus of proteins in a co-translational process termed N-myristoylation.{17231} The sirtuin SIRT6 removes this acyl group from myristoylated TNF-α, enhancing secretion.{22694} Myristic acid alkyne is a form of this myristic acid (Item No. 13351) with an ω-terminal alkyne. Such terminal alkyne groups can be used in linking reactions, known as click chemistry, characterized by high dependability and specificity of azide-alkyne bioconjugation reactions.{17991,17992} Click chemistry has only recently been applied to the study of lipids.{22694,16188}  

     

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  • Myristic acid is a 14-carbon saturated (14:0) fatty acid. In vivo, it is commonly added covalently to the N-terminus of proteins in a co-translational process termed N-myristoylation.{17231} The sirtuin SIRT6 removes this acyl group from myristoylated TNF-α, enhancing secretion.{22694} Myristic acid alkyne is a form of this myristic acid (Item No. 13351) with an ω-terminal alkyne. Such terminal alkyne groups can be used in linking reactions, known as click chemistry, characterized by high dependability and specificity of azide-alkyne bioconjugation reactions.{17991,17992} Click chemistry has only recently been applied to the study of lipids.{22694,16188}  

     

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  • Myristic acid is a saturated fatty acid commonly found in animal and vegetable fats that is frequently used in cosmetics, soaps, perfumes, and flavorings. It increases low density lipoprotein cholesterol making it one of the most hypercholesterolemic of the saturated fatty acids.{14160} Myristic acid ethyl ester is a more hydrophobic form of the free acid. It is a marker of excessive ethanol consumption that can be isolated from the hair of an individual.{14159}  

     

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    SKU:10008197 - 1 g

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  • Myristic acid is a saturated fatty acid commonly found in animal and vegetable fats that is frequently used in cosmetics, soaps, perfumes, and flavorings. It increases low density lipoprotein cholesterol making it one of the most hypercholesterolemic of the saturated fatty acids.{14160} Myristic acid ethyl ester is a more hydrophobic form of the free acid. It is a marker of excessive ethanol consumption that can be isolated from the hair of an individual.{14159}  

     

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    SKU:10008197 - 100 mg

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  • Myristic acid is a saturated fatty acid commonly found in animal and vegetable fats that is frequently used in cosmetics, soaps, perfumes, and flavorings. It increases low density lipoprotein cholesterol making it one of the most hypercholesterolemic of the saturated fatty acids.{14160} Myristic acid ethyl ester is a more hydrophobic form of the free acid. It is a marker of excessive ethanol consumption that can be isolated from the hair of an individual.{14159}  

     

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    SKU:10008197 - 500 mg

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  • Myristic acid methyl ester is an esterified version of the free acid, which is less water soluble but more amenable for the formulation of myristate-containing diets and dietary supplements.  

     

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    SKU:9001867 - 1 g

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  • Myristic acid methyl ester is an esterified version of the free acid, which is less water soluble but more amenable for the formulation of myristate-containing diets and dietary supplements.  

     

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    SKU:9001867 - 500 mg

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  • Myristic Acid methyl ester-d27 is intended for use as an internal standard for the quantification of myristic acid methyl ester (Item No. 9001867) by GC- or LC-MS. Myristic acid methyl ester is an esterified version of the free acid, which is less water soluble but more amenable for the formulation of myristate-containing diets and dietary supplements.  

     

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    SKU:28594 - 10 mg

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  • Myristic Acid methyl ester-d27 is intended for use as an internal standard for the quantification of myristic acid methyl ester (Item No. 9001867) by GC- or LC-MS. Myristic acid methyl ester is an esterified version of the free acid, which is less water soluble but more amenable for the formulation of myristate-containing diets and dietary supplements.  

     

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    SKU:28594 - 25 mg

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  • Myristic Acid methyl ester-d27 is intended for use as an internal standard for the quantification of myristic acid methyl ester (Item No. 9001867) by GC- or LC-MS. Myristic acid methyl ester is an esterified version of the free acid, which is less water soluble but more amenable for the formulation of myristate-containing diets and dietary supplements.  

     

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    SKU:28594 - 5 mg

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  • Myristic Acid methyl ester-d27 is intended for use as an internal standard for the quantification of myristic acid methyl ester (Item No. 9001867) by GC- or LC-MS. Myristic acid methyl ester is an esterified version of the free acid, which is less water soluble but more amenable for the formulation of myristate-containing diets and dietary supplements.  

     

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    SKU:28594 - 50 mg

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  • Myristic acid-13C is intended for use as an internal standard for the quantification of myristic acid (Item No. 13351) by GC- or LC-MS. Myristic acid is a 14-carbon saturated fatty acid. It is incorporated into myristoyl coenzyme A (myristoyl-CoA) and transferred by N-myristoyltransferase to the N-terminal glycine of certain proteins either during translation to modify protein activity or post-translationally in apoptotic cells.{41877,41878}  

     

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    SKU:29463 - 250 mg

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  • Myristic acid-13C is intended for use as an internal standard for the quantification of myristic acid (Item No. 13351) by GC- or LC-MS. Myristic acid is a 14-carbon saturated fatty acid. It is incorporated into myristoyl coenzyme A (myristoyl-CoA) and transferred by N-myristoyltransferase to the N-terminal glycine of certain proteins either during translation to modify protein activity or post-translationally in apoptotic cells.{41877,41878}  

     

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    SKU:29463 - 500 mg

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  • Myristic acid-d2 is intended for use as an internal standard for the quantification of myristic acid (Item No. 13351) by GC- or LC-MS. Myristic acid is a 14-carbon saturated fatty acid. It is incorporated into myristoyl coenzyme A (myristoyl-CoA) and transferred by N-myristoyltransferase to the N-terminal glycine of certain proteins either during translation to modify protein activity or post-translationally in apoptotic cells.{41877,41878}  

     

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    SKU:29411 - 100 mg

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  • Myristic acid-d2 is intended for use as an internal standard for the quantification of myristic acid (Item No. 13351) by GC- or LC-MS. Myristic acid is a 14-carbon saturated fatty acid. It is incorporated into myristoyl coenzyme A (myristoyl-CoA) and transferred by N-myristoyltransferase to the N-terminal glycine of certain proteins either during translation to modify protein activity or post-translationally in apoptotic cells.{41877,41878}  

     

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    SKU:29411 - 250 mg

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  • Myristic acid-d2 is intended for use as an internal standard for the quantification of myristic acid (Item No. 13351) by GC- or LC-MS. Myristic acid is a 14-carbon saturated fatty acid. It is incorporated into myristoyl coenzyme A (myristoyl-CoA) and transferred by N-myristoyltransferase to the N-terminal glycine of certain proteins either during translation to modify protein activity or post-translationally in apoptotic cells.{41877,41878}  

     

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    Cayman
    SKU:29411 - 50 mg

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  • Myristic acid-d2 is intended for use as an internal standard for the quantification of myristic acid (Item No. 13351) by GC- or LC-MS. Myristic acid is a 14-carbon saturated fatty acid. It is incorporated into myristoyl coenzyme A (myristoyl-CoA) and transferred by N-myristoyltransferase to the N-terminal glycine of certain proteins either during translation to modify protein activity or post-translationally in apoptotic cells.{41877,41878}  

     

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    SKU:29411 - 500 mg

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  • Myristic acid-d27 is intended for use as an internal standard for the quantification of myristic acid (Item No. 13351) by GC- or LC-MS. Myristic acid is a 14-carbon saturated fatty acid. It is incorporated into myristoyl coenzyme A (myristoyl-CoA) and transferred by N-myristoyltransferase to the N-terminal glycine of certain proteins either during translation to modify protein activity or post-translationally in apoptotic cells.{41877,41878}  

     

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    SKU:9003317 - 100 mg

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  • Myristic acid-d27 is intended for use as an internal standard for the quantification of myristic acid (Item No. 13351) by GC- or LC-MS. Myristic acid is a 14-carbon saturated fatty acid. It is incorporated into myristoyl coenzyme A (myristoyl-CoA) and transferred by N-myristoyltransferase to the N-terminal glycine of certain proteins either during translation to modify protein activity or post-translationally in apoptotic cells.{41877,41878}  

     

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    SKU:9003317 - 250 mg

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  • Myristic acid-d27 is intended for use as an internal standard for the quantification of myristic acid (Item No. 13351) by GC- or LC-MS. Myristic acid is a 14-carbon saturated fatty acid. It is incorporated into myristoyl coenzyme A (myristoyl-CoA) and transferred by N-myristoyltransferase to the N-terminal glycine of certain proteins either during translation to modify protein activity or post-translationally in apoptotic cells.{41877,41878}  

     

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    SKU:9003317 - 500 mg

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  • Myristicin is an alkenylbenzene present in small amounts in the essential oil of nutmeg that is reported to act as a serotonin receptor antagonist, a weak monamine oxidase inhibitor, and to produce hallucinogenic effects.{24226} Abuse of myristicin has led to fatal poisoning, which has prompted improved methods for HPLC determination of myristicin in human plasma.{24440} This product is intended for forensic and research purposes.  

     

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  • Myristicin is an alkenylbenzene present in small amounts in the essential oil of nutmeg that is reported to act as a serotonin receptor antagonist, a weak monamine oxidase inhibitor, and to produce hallucinogenic effects.{24226} Abuse of myristicin has led to fatal poisoning, which has prompted improved methods for HPLC determination of myristicin in human plasma.{24440} This product is intended for forensic and research purposes.  

     

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  • Myristicin is an alkenylbenzene present in small amounts in the essential oil of nutmeg that is reported to act as a serotonin receptor antagonist, a weak monamine oxidase inhibitor, and to produce hallucinogenic effects.{24226} Abuse of myristicin has led to fatal poisoning, which has prompted improved methods for HPLC determination of myristicin in human plasma.{24440} This product is intended for forensic and research purposes.  

     

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  • Myristoleic acid is a monounsaturated fatty acid found in the fruit extract of S. repens and in dairy extracts.{14760, 14761} It induces apoptosis and necrosis in human prostate cancer LNCaP cells at a rate of 8.8% and 8.1%, respectively.{14760} Myristoleic acid inhibits C. albicans germination in vitro with a minimal inhibitory concentration (MIC) of 9 µM.{14761} Furthermore, myristoleic acid inhibits osteogenesis in vitro via interference with cytoskeletal rearrangement and prevents RANKL-induced bone loss and osteoclast formation in mice.{39234}  

     

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    SKU:9002461 - 100 mg

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  • Myristoleic acid is a monounsaturated fatty acid found in the fruit extract of S. repens and in dairy extracts.{14760, 14761} It induces apoptosis and necrosis in human prostate cancer LNCaP cells at a rate of 8.8% and 8.1%, respectively.{14760} Myristoleic acid inhibits C. albicans germination in vitro with a minimal inhibitory concentration (MIC) of 9 µM.{14761} Furthermore, myristoleic acid inhibits osteogenesis in vitro via interference with cytoskeletal rearrangement and prevents RANKL-induced bone loss and osteoclast formation in mice.{39234}  

     

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    SKU:9002461 - 250 mg

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  • Myristoleic acid is a monounsaturated fatty acid found in the fruit extract of S. repens and in dairy extracts.{14760, 14761} It induces apoptosis and necrosis in human prostate cancer LNCaP cells at a rate of 8.8% and 8.1%, respectively.{14760} Myristoleic acid inhibits C. albicans germination in vitro with a minimal inhibitory concentration (MIC) of 9 µM.{14761} Furthermore, myristoleic acid inhibits osteogenesis in vitro via interference with cytoskeletal rearrangement and prevents RANKL-induced bone loss and osteoclast formation in mice.{39234}  

     

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    SKU:9002461 - 50 mg

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  • Myristoleic acid is a cytotoxic component from the fruit extract of S. repens.{14760} It induces apoptosis and necrosis in human prostate cancer LNCaP cells at a rate of 8.8% and 8.1%, respectively.{14760} Furthermore, myristoleic acid found in the by-products for making cheese is one of three fatty acids that are most active at inhibiting Candida albicans germination.{14761} It has a minimal inhibitory concentration (MIC) of 9 µM in vivo.{14762} Myristoleic acid methyl ester is a more hydrophobic form of the free acid.  

     

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    SKU:10008581 - 1 g

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  • Myristoleic acid is a cytotoxic component from the fruit extract of S. repens.{14760} It induces apoptosis and necrosis in human prostate cancer LNCaP cells at a rate of 8.8% and 8.1%, respectively.{14760} Furthermore, myristoleic acid found in the by-products for making cheese is one of three fatty acids that are most active at inhibiting Candida albicans germination.{14761} It has a minimal inhibitory concentration (MIC) of 9 µM in vivo.{14762} Myristoleic acid methyl ester is a more hydrophobic form of the free acid.  

     

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    SKU:10008581 - 100 mg

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  • Myristoleic acid is a cytotoxic component from the fruit extract of S. repens.{14760} It induces apoptosis and necrosis in human prostate cancer LNCaP cells at a rate of 8.8% and 8.1%, respectively.{14760} Furthermore, myristoleic acid found in the by-products for making cheese is one of three fatty acids that are most active at inhibiting Candida albicans germination.{14761} It has a minimal inhibitory concentration (MIC) of 9 µM in vivo.{14762} Myristoleic acid methyl ester is a more hydrophobic form of the free acid.  

     

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    SKU:10008581 - 50 mg

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  • Myristoleic acid is a cytotoxic component from the fruit extract of S. repens.{14760} It induces apoptosis and necrosis in human prostate cancer LNCaP cells at a rate of 8.8% and 8.1%, respectively.{14760} Furthermore, myristoleic acid found in the by-products for making cheese is one of three fatty acids that are most active at inhibiting Candida albicans germination.{14761} It has a minimal inhibitory concentration (MIC) of 9 µM in vivo.{14762} Myristoleic acid methyl ester is a more hydrophobic form of the free acid.  

     

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    SKU:10008581 - 500 mg

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  • Myristoyl ethanolamide is a member of the family of fatty N-acyl ethanolamines collectively called endocannabinoids.{1202,1712,13153} Myristic acid is typically detected at low levels in rat cerebrospinal fluid, however the specific role and relative importance of its ethanolamine metabolite have not been yet determined.{22439}  

     

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    SKU:9001742 - 10 mg

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  • Myristoyl ethanolamide is a member of the family of fatty N-acyl ethanolamines collectively called endocannabinoids.{1202,1712,13153} Myristic acid is typically detected at low levels in rat cerebrospinal fluid, however the specific role and relative importance of its ethanolamine metabolite have not been yet determined.{22439}  

     

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    SKU:9001742 - 100 mg

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  • Myristoyl ethanolamide is a member of the family of fatty N-acyl ethanolamines collectively called endocannabinoids.{1202,1712,13153} Myristic acid is typically detected at low levels in rat cerebrospinal fluid, however the specific role and relative importance of its ethanolamine metabolite have not been yet determined.{22439}  

     

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    SKU:9001742 - 5 mg

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  • Myristoyl ethanolamide is a member of the family of fatty N-acyl ethanolamines collectively called endocannabinoids.{1202,1712,13153} Myristic acid is typically detected at low levels in rat cerebrospinal fluid, however the specific role and relative importance of its ethanolamine metabolite have not been yet determined.{22439}  

     

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    SKU:9001742 - 50 mg

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  • Myristoyl-Gly-OH is a lipidated amino acid and fatty amide. It has been used as an immunogen to raise antibodies against myristoylated proteins and as a synthetic intermediate in the synthesis of lipopeptides.{60100,60101}  

     

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    SKU:30107 - 1 mg

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  • Myristoyl-Gly-OH is a lipidated amino acid and fatty amide. It has been used as an immunogen to raise antibodies against myristoylated proteins and as a synthetic intermediate in the synthesis of lipopeptides.{60100,60101}  

     

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    SKU:30107 - 10 mg

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  • Myristoyl-Gly-OH is a lipidated amino acid and fatty amide. It has been used as an immunogen to raise antibodies against myristoylated proteins and as a synthetic intermediate in the synthesis of lipopeptides.{60100,60101}  

     

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    SKU:30107 - 25 mg

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  • Myristoyl-Gly-OH is a lipidated amino acid and fatty amide. It has been used as an immunogen to raise antibodies against myristoylated proteins and as a synthetic intermediate in the synthesis of lipopeptides.{60100,60101}  

     

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    SKU:30107 - 5 mg

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  • Myristoyl-L-carnitine is a naturally occurring long-chain acylcarnitine.{42563} Plasma levels of myristoyl-L-carnitine are decreased in patients with chronic fatigue syndrome and increased in patients with end-stage renal disease.{42563,42564}  

     

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    SKU:26559 - 10 mg

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  • Myristoyl-L-carnitine is a naturally occurring long-chain acylcarnitine.{42563} Plasma levels of myristoyl-L-carnitine are decreased in patients with chronic fatigue syndrome and increased in patients with end-stage renal disease.{42563,42564}  

     

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    SKU:26559 - 25 mg

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  • Myristoyl-L-carnitine is a naturally occurring long-chain acylcarnitine.{42563} Plasma levels of myristoyl-L-carnitine are decreased in patients with chronic fatigue syndrome and increased in patients with end-stage renal disease.{42563,42564}  

     

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    SKU:26559 - 50 mg

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  • Myristoyl-L-carnitine-d3 is intended for use as an internal standard for the quantification of myristoyl-L-carnitine (Item No. 26559) by GC- or LC-MS. Myristoyl-L-carnitine is a naturally occurring long-chain acylcarnitine.{42563} Plasma levels of myristoyl-L-carnitine are decreased in patients with chronic fatigue syndrome and increased in patients with end-stage renal disease.{42563,42564}  

     

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    SKU:26581 - 1 mg

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  • Myristoyl-L-carnitine-d3 is intended for use as an internal standard for the quantification of myristoyl-L-carnitine (Item No. 26559) by GC- or LC-MS. Myristoyl-L-carnitine is a naturally occurring long-chain acylcarnitine.{42563} Plasma levels of myristoyl-L-carnitine are decreased in patients with chronic fatigue syndrome and increased in patients with end-stage renal disease.{42563,42564}  

     

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    SKU:26581 - 5 mg

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  • Myrothecine A is a trichothecene mycotoxin that has been found in M. roridum and has anticancer activities.{48753,48754} It inhibits proliferation of A549, MCF-7, HepG2, and SMMC-7721 cancer cells (IC50s = 95, 70, 60, and 25 µM, respectively).{48753} Myrothecine A (50 µM) induces G1 cell cycle arrest in HepG2 cells, as well as increases Bax and cleaved caspase-3, -5, and -8 levels and induces apoptosis in SMMC-7721 cells.{48753,48754}  

     

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    SKU:28193 - 1 mg

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  • Myrtillin is a natural anthocyanin found in plants. It is the 3-glucoside of delphinidin. Anthocyanins, including myrtillin, are potent antioxidants.{26210,26209,23825}  

     

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  • Myrtillin is a natural anthocyanin found in plants. It is the 3-glucoside of delphinidin. Anthocyanins, including myrtillin, are potent antioxidants.{26210,26209,23825}  

     

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  • Myrtillin is a natural anthocyanin found in plants. It is the 3-glucoside of delphinidin. Anthocyanins, including myrtillin, are potent antioxidants.{26210,26209,23825}  

     

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    Cayman
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  • Myrtillin is a natural anthocyanin found in plants. It is the 3-glucoside of delphinidin. Anthocyanins, including myrtillin, are potent antioxidants.{26210,26209,23825}  

     

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    Cayman
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  • Myxochelin A is a microbial metabolite that has been found in A. disciformis and has diverse biological activities.{53609} It is active against Gram-positive bacteria, including B. cereus, S. aureus, and M. luteus, but not Gram-negative bacteria or fungi in an agar diffusion assay when used at a concentration of 80 µg/disc. Myxochelin A inhibits 5-lipoxygenase (5-LO) activity with an IC50 value of 1.9 µM for the recombinant human enzyme.{53610} It is cytotoxic to 26-L5 colon cancer cells when used at a concentration of 3 µg/ml.{53611}  

     

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    Cayman
    SKU:26422 - 1 mg

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  • MZ1 is a hybrid compound that drives the selective proteasomal degradation of bromodomain-containing protein 4 (BRD4).{33482} It is characterized as a proteolysis-targeting chimera (PROTAC) and contains JQ-1, which binds bromo- and extra-terminal (BET) proteins, linked to a ligand for the E3 ubiquitin ligase VHL. MZ1 induces the selective degradation of BRD4 in HeLa cells when used at 0.1-0.5 µM.{33482} At concentrations of 2-10 µM, MZ1 causes the removal of BRD2, BRD3, and BRD4.{33482} BRD protein removal is evident within four hours of adding MZ1 and persists for at least 48 hours, unless MZ1 is removed.{33482}  

     

    Brand:
    Cayman
    SKU:21622 -

    Out of stock

  • MZ1 is a hybrid compound that drives the selective proteasomal degradation of bromodomain-containing protein 4 (BRD4).{33482} It is characterized as a proteolysis-targeting chimera (PROTAC) and contains JQ-1, which binds bromo- and extra-terminal (BET) proteins, linked to a ligand for the E3 ubiquitin ligase VHL. MZ1 induces the selective degradation of BRD4 in HeLa cells when used at 0.1-0.5 µM.{33482} At concentrations of 2-10 µM, MZ1 causes the removal of BRD2, BRD3, and BRD4.{33482} BRD protein removal is evident within four hours of adding MZ1 and persists for at least 48 hours, unless MZ1 is removed.{33482}  

     

    Brand:
    Cayman
    SKU:21622 -

    Out of stock

  • MZ1 is a hybrid compound that drives the selective proteasomal degradation of bromodomain-containing protein 4 (BRD4).{33482} It is characterized as a proteolysis-targeting chimera (PROTAC) and contains JQ-1, which binds bromo- and extra-terminal (BET) proteins, linked to a ligand for the E3 ubiquitin ligase VHL. MZ1 induces the selective degradation of BRD4 in HeLa cells when used at 0.1-0.5 µM.{33482} At concentrations of 2-10 µM, MZ1 causes the removal of BRD2, BRD3, and BRD4.{33482} BRD protein removal is evident within four hours of adding MZ1 and persists for at least 48 hours, unless MZ1 is removed.{33482}  

     

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    Cayman
    SKU:21622 -

    Out of stock

  • N-(1-(3,4-Dihydroxyphenyl)propan-2-yl)oleamide binds to the cannabinoid 1 (CB1) receptor with a Ki value of 365 nM in a radioligand binding assay using rat brain homogenate.{36053} It has an EC50 value of 698 nM for the peroxisome proliferator-activated receptor α (PPARα) in a luciferase reporter assay and, in rats, it decreases food intake. It does not inhibit fatty acid amide hydrolase (FAAH).  

     

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    Cayman
    SKU:9002954 - 1 mg

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  • N-(1-(3,4-Dihydroxyphenyl)propan-2-yl)oleamide binds to the cannabinoid 1 (CB1) receptor with a Ki value of 365 nM in a radioligand binding assay using rat brain homogenate.{36053} It has an EC50 value of 698 nM for the peroxisome proliferator-activated receptor α (PPARα) in a luciferase reporter assay and, in rats, it decreases food intake. It does not inhibit fatty acid amide hydrolase (FAAH).  

     

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    Cayman
    SKU:9002954 - 100 µg

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  • N-(1-(3,4-Dihydroxyphenyl)propan-2-yl)oleamide binds to the cannabinoid 1 (CB1) receptor with a Ki value of 365 nM in a radioligand binding assay using rat brain homogenate.{36053} It has an EC50 value of 698 nM for the peroxisome proliferator-activated receptor α (PPARα) in a luciferase reporter assay and, in rats, it decreases food intake. It does not inhibit fatty acid amide hydrolase (FAAH).  

     

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    Cayman
    SKU:9002954 - 500 µg

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  • N-(2-Aminoethyl)maleimide is a thiol-reactive cross-linking agent.{52503,52504} It has been used in the synthesis of maleimide-functionalized heparin hydrogels in the development of growth factor delivery systems and radiotracers for thiol-mediated protein labelling.  

     

    Brand:
    Cayman
    SKU:30530 - 1 g

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  • N-(2-Aminoethyl)maleimide is a thiol-reactive cross-linking agent.{52503,52504} It has been used in the synthesis of maleimide-functionalized heparin hydrogels in the development of growth factor delivery systems and radiotracers for thiol-mediated protein labelling.  

     

    Brand:
    Cayman
    SKU:30530 - 250 mg

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  • N-(2-Aminoethyl)maleimide is a thiol-reactive cross-linking agent.{52503,52504} It has been used in the synthesis of maleimide-functionalized heparin hydrogels in the development of growth factor delivery systems and radiotracers for thiol-mediated protein labelling.  

     

    Brand:
    Cayman
    SKU:30530 - 500 mg

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  • N-(2-Fluorophenethyl)-5-(2-methoxyphenyl)picolinamide is an inhibitor of hypoxia-inducible factor (HIF-1) signaling (IC50 = 0.32 μM in a cell-based hypoxia responsive element (HRE) reporter assay under hypoxic conditions).{50774} It inhibits hypoxia-induced increases in HIF-1α levels in MDA-MB-231, SKOV3, and HeLa cells in a concentration-dependent manner. N-(2-Fluorophenethyl)-5-(2-methoxyphenyl)picolinamide also inhibits hypoxia-induced VEGF expression and capillary-like tube formation in human umbilical vein endothelial cells (HUVECs) and inhibits migration and invasion of MDA-MB-231 cells in wound healing and transwell assays under hypoxic conditions. It also reduces lung metastasis in an MDA-MB-231 mouse xenograft model when administered at doses of 15 and 30 mg/kg every other day.  

     

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    Cayman
    SKU:29740 - 1 mg

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  • N-(2-Fluorophenethyl)-5-(2-methoxyphenyl)picolinamide is an inhibitor of hypoxia-inducible factor (HIF-1) signaling (IC50 = 0.32 μM in a cell-based hypoxia responsive element (HRE) reporter assay under hypoxic conditions).{50774} It inhibits hypoxia-induced increases in HIF-1α levels in MDA-MB-231, SKOV3, and HeLa cells in a concentration-dependent manner. N-(2-Fluorophenethyl)-5-(2-methoxyphenyl)picolinamide also inhibits hypoxia-induced VEGF expression and capillary-like tube formation in human umbilical vein endothelial cells (HUVECs) and inhibits migration and invasion of MDA-MB-231 cells in wound healing and transwell assays under hypoxic conditions. It also reduces lung metastasis in an MDA-MB-231 mouse xenograft model when administered at doses of 15 and 30 mg/kg every other day.  

     

    Brand:
    Cayman
    SKU:29740 - 10 mg

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  • N-(2-Fluorophenethyl)-5-(2-methoxyphenyl)picolinamide is an inhibitor of hypoxia-inducible factor (HIF-1) signaling (IC50 = 0.32 μM in a cell-based hypoxia responsive element (HRE) reporter assay under hypoxic conditions).{50774} It inhibits hypoxia-induced increases in HIF-1α levels in MDA-MB-231, SKOV3, and HeLa cells in a concentration-dependent manner. N-(2-Fluorophenethyl)-5-(2-methoxyphenyl)picolinamide also inhibits hypoxia-induced VEGF expression and capillary-like tube formation in human umbilical vein endothelial cells (HUVECs) and inhibits migration and invasion of MDA-MB-231 cells in wound healing and transwell assays under hypoxic conditions. It also reduces lung metastasis in an MDA-MB-231 mouse xenograft model when administered at doses of 15 and 30 mg/kg every other day.  

     

    Brand:
    Cayman
    SKU:29740 - 5 mg

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  • N-(2-hydroxyethyl)-Naphthalimide is an N-substituted 1,8-naphthalimide used as a fluorescent probe and as a precursor for protection of amine groups.{28744} It is used to detect nucleic acids and their precursors, which quench the fluorescence of N-(2-hydroxyethyl)-naphthalimide.{41257} Nucleic acids quench the fluorescence most strongly followed by nucleosides and nucleobases, of which purine bases quench more strongly than pyrimidine bases. N-(2-hydroxyethyl)-Naphthalimide is electroactive and forms adducts with 1,3-dihydroxy benzene and 1,3,5-trihydroxybenzene.{28744} N-(2-hydroxyethyl)-Naphthalimide displays excitation spectra of 330-333 and 344-347 nm with emission spectra of 366-378 nm in solvents of varying polarities, with a higher Stokes shift in less polar solvents.{41256}  

     

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    Cayman
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  • N-(2-hydroxyethyl)-Naphthalimide is an N-substituted 1,8-naphthalimide used as a fluorescent probe and as a precursor for protection of amine groups.{28744} It is used to detect nucleic acids and their precursors, which quench the fluorescence of N-(2-hydroxyethyl)-naphthalimide.{41257} Nucleic acids quench the fluorescence most strongly followed by nucleosides and nucleobases, of which purine bases quench more strongly than pyrimidine bases. N-(2-hydroxyethyl)-Naphthalimide is electroactive and forms adducts with 1,3-dihydroxy benzene and 1,3,5-trihydroxybenzene.{28744} N-(2-hydroxyethyl)-Naphthalimide displays excitation spectra of 330-333 and 344-347 nm with emission spectra of 366-378 nm in solvents of varying polarities, with a higher Stokes shift in less polar solvents.{41256}  

     

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    Cayman
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  • N-(2-hydroxyethyl)-Naphthalimide is an N-substituted 1,8-naphthalimide used as a fluorescent probe and as a precursor for protection of amine groups.{28744} It is used to detect nucleic acids and their precursors, which quench the fluorescence of N-(2-hydroxyethyl)-naphthalimide.{41257} Nucleic acids quench the fluorescence most strongly followed by nucleosides and nucleobases, of which purine bases quench more strongly than pyrimidine bases. N-(2-hydroxyethyl)-Naphthalimide is electroactive and forms adducts with 1,3-dihydroxy benzene and 1,3,5-trihydroxybenzene.{28744} N-(2-hydroxyethyl)-Naphthalimide displays excitation spectra of 330-333 and 344-347 nm with emission spectra of 366-378 nm in solvents of varying polarities, with a higher Stokes shift in less polar solvents.{41256}  

     

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  • N-(2-phenylethyl)-indomethacin amide (N-2PIA) is one of several aromatic amides of indomethacin reported to be potent and selective reversible inhibitors of COX-2.{8243} N-2PIA inhibits human recombinant and ovine COX-2 with IC50 values of 0.06 and 0.125 µM, respectively.{8243,8513} It is over 400 times less potent as an inhibitor of human recombinant and ovine COX-1. N-2PIA shows anti-inflammatory, antiangiogenic, and cancer chemopreventive activity in various experimental models.{8243}  

     

    Brand:
    Cayman
    SKU:70272 - 1 mg

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  • N-(2-phenylethyl)-indomethacin amide (N-2PIA) is one of several aromatic amides of indomethacin reported to be potent and selective reversible inhibitors of COX-2.{8243} N-2PIA inhibits human recombinant and ovine COX-2 with IC50 values of 0.06 and 0.125 µM, respectively.{8243,8513} It is over 400 times less potent as an inhibitor of human recombinant and ovine COX-1. N-2PIA shows anti-inflammatory, antiangiogenic, and cancer chemopreventive activity in various experimental models.{8243}  

     

    Brand:
    Cayman
    SKU:70272 - 10 mg

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  • N-(2-phenylethyl)-indomethacin amide (N-2PIA) is one of several aromatic amides of indomethacin reported to be potent and selective reversible inhibitors of COX-2.{8243} N-2PIA inhibits human recombinant and ovine COX-2 with IC50 values of 0.06 and 0.125 µM, respectively.{8243,8513} It is over 400 times less potent as an inhibitor of human recombinant and ovine COX-1. N-2PIA shows anti-inflammatory, antiangiogenic, and cancer chemopreventive activity in various experimental models.{8243}  

     

    Brand:
    Cayman
    SKU:70272 - 5 mg

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  • N-(2-phenylethyl)-indomethacin amide (N-2PIA) is one of several aromatic amides of indomethacin reported to be potent and selective reversible inhibitors of COX-2.{8243} N-2PIA inhibits human recombinant and ovine COX-2 with IC50 values of 0.06 and 0.125 µM, respectively.{8243,8513} It is over 400 times less potent as an inhibitor of human recombinant and ovine COX-1. N-2PIA shows anti-inflammatory, antiangiogenic, and cancer chemopreventive activity in various experimental models.{8243}  

     

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    Cayman
    SKU:70272 - 50 mg

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  • Lidocaine is an anesthetic that blocks voltage-gated Na+ channels (IC50 = 128 µM) with selectivity over L-type Ca2+ channels and GABAA receptors.{25312} Lidocaine can also have pronociceptive effects by activating the transient receptor potential (TRP) channel TRPA1.{23938} N-(2,6-Dimethylphenyl)-2-(ethylmethylamino)acetamide is a lidocaine impurity.{29992,29993}  

     

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    Cayman
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  • Lidocaine is an anesthetic that blocks voltage-gated Na+ channels (IC50 = 128 µM) with selectivity over L-type Ca2+ channels and GABAA receptors.{25312} Lidocaine can also have pronociceptive effects by activating the transient receptor potential (TRP) channel TRPA1.{23938} N-(2,6-Dimethylphenyl)-2-(ethylmethylamino)acetamide is a lidocaine impurity.{29992,29993}  

     

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  • Lidocaine is an anesthetic that blocks voltage-gated Na+ channels (IC50 = 128 µM) with selectivity over L-type Ca2+ channels and GABAA receptors.{25312} Lidocaine can also have pronociceptive effects by activating the transient receptor potential (TRP) channel TRPA1.{23938} N-(2,6-Dimethylphenyl)-2-(ethylmethylamino)acetamide is a lidocaine impurity.{29992,29993}  

     

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    Cayman
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  • N-(3-Aminopropyl)acetamide is a monoacetylated polyamine that can be used as a building block in the synthesis of heterocyclic compounds. Polyamines are promising biochemical markers of cancer and many other pathophysiological conditions, thus their concentrations in biological fluids have been analyzed.{32370}  

     

    Brand:
    Cayman
    SKU:9002787 - 1 mg

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  • N-(3-Aminopropyl)acetamide is a monoacetylated polyamine that can be used as a building block in the synthesis of heterocyclic compounds. Polyamines are promising biochemical markers of cancer and many other pathophysiological conditions, thus their concentrations in biological fluids have been analyzed.{32370}  

     

    Brand:
    Cayman
    SKU:9002787 - 10 mg

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  • N-(3-Aminopropyl)acetamide is a monoacetylated polyamine that can be used as a building block in the synthesis of heterocyclic compounds. Polyamines are promising biochemical markers of cancer and many other pathophysiological conditions, thus their concentrations in biological fluids have been analyzed.{32370}  

     

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    Cayman
    SKU:9002787 - 5 mg

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  • N-(3-hydroxy-7-cis tetradecenoyl)-L-Homoserine lactone is a long-chain N-acyl-homoserine lactone (AHL) produced by some Gram-negative bacteria and is involved in quorum sensing.{33808} Quorum sensing enables bacteria to change gene expression based on cues from nearby bacteria and from eukaryotic hosts about nutrients, environmental conditions, or threats.{15399} Due to the benefit of quorum sensing for bacterial survival, quorum sensing molecules are potential targets for controlling bacterial infections.{13466} In mouse and human leukocyte immunoassays using LPS-stimulated macrophages, N-(3-hydroxy-7-cis tetradecenoyl)-L-homoserine lactone did not have an effect on cytokine or antibody production.{33809}  

     

    Brand:
    Cayman
    SKU:9002939 - 1 mg

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  • N-(3-hydroxy-7-cis tetradecenoyl)-L-Homoserine lactone is a long-chain N-acyl-homoserine lactone (AHL) produced by some Gram-negative bacteria and is involved in quorum sensing.{33808} Quorum sensing enables bacteria to change gene expression based on cues from nearby bacteria and from eukaryotic hosts about nutrients, environmental conditions, or threats.{15399} Due to the benefit of quorum sensing for bacterial survival, quorum sensing molecules are potential targets for controlling bacterial infections.{13466} In mouse and human leukocyte immunoassays using LPS-stimulated macrophages, N-(3-hydroxy-7-cis tetradecenoyl)-L-homoserine lactone did not have an effect on cytokine or antibody production.{33809}  

     

    Brand:
    Cayman
    SKU:9002939 - 10 mg

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  • N-(3-hydroxy-7-cis tetradecenoyl)-L-Homoserine lactone is a long-chain N-acyl-homoserine lactone (AHL) produced by some Gram-negative bacteria and is involved in quorum sensing.{33808} Quorum sensing enables bacteria to change gene expression based on cues from nearby bacteria and from eukaryotic hosts about nutrients, environmental conditions, or threats.{15399} Due to the benefit of quorum sensing for bacterial survival, quorum sensing molecules are potential targets for controlling bacterial infections.{13466} In mouse and human leukocyte immunoassays using LPS-stimulated macrophages, N-(3-hydroxy-7-cis tetradecenoyl)-L-homoserine lactone did not have an effect on cytokine or antibody production.{33809}  

     

    Brand:
    Cayman
    SKU:9002939 - 25 mg

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  • N-(3-hydroxy-7-cis tetradecenoyl)-L-Homoserine lactone is a long-chain N-acyl-homoserine lactone (AHL) produced by some Gram-negative bacteria and is involved in quorum sensing.{33808} Quorum sensing enables bacteria to change gene expression based on cues from nearby bacteria and from eukaryotic hosts about nutrients, environmental conditions, or threats.{15399} Due to the benefit of quorum sensing for bacterial survival, quorum sensing molecules are potential targets for controlling bacterial infections.{13466} In mouse and human leukocyte immunoassays using LPS-stimulated macrophages, N-(3-hydroxy-7-cis tetradecenoyl)-L-homoserine lactone did not have an effect on cytokine or antibody production.{33809}  

     

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    Cayman
    SKU:9002939 - 5 mg

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  • N-(3-hydroxyphenyl)-Arachidonoyl amide (3-HPA) is an analog of AM404 (N-(4-hydroxyphenyl)-arachidonoyl amide), which is a selective inhibitor of carrier-mediated transport of arachidonoyl ethanolamide (AEA).{4894} 3-HPA is metabolized by both cyclooxygenase-1 (COX-1) and COX-2 and was found to selectively and irreversibly inhibit COX-2 with an IC50 value of 2 µM.{14589}  

     

    Brand:
    Cayman
    SKU:10007704 - 10 mg

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  • N-(3-hydroxyphenyl)-Arachidonoyl amide (3-HPA) is an analog of AM404 (N-(4-hydroxyphenyl)-arachidonoyl amide), which is a selective inhibitor of carrier-mediated transport of arachidonoyl ethanolamide (AEA).{4894} 3-HPA is metabolized by both cyclooxygenase-1 (COX-1) and COX-2 and was found to selectively and irreversibly inhibit COX-2 with an IC50 value of 2 µM.{14589}  

     

    Brand:
    Cayman
    SKU:10007704 - 100 mg

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  • N-(3-hydroxyphenyl)-Arachidonoyl amide (3-HPA) is an analog of AM404 (N-(4-hydroxyphenyl)-arachidonoyl amide), which is a selective inhibitor of carrier-mediated transport of arachidonoyl ethanolamide (AEA).{4894} 3-HPA is metabolized by both cyclooxygenase-1 (COX-1) and COX-2 and was found to selectively and irreversibly inhibit COX-2 with an IC50 value of 2 µM.{14589}  

     

    Brand:
    Cayman
    SKU:10007704 - 5 mg

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  • N-(3-hydroxyphenyl)-Arachidonoyl amide (3-HPA) is an analog of AM404 (N-(4-hydroxyphenyl)-arachidonoyl amide), which is a selective inhibitor of carrier-mediated transport of arachidonoyl ethanolamide (AEA).{4894} 3-HPA is metabolized by both cyclooxygenase-1 (COX-1) and COX-2 and was found to selectively and irreversibly inhibit COX-2 with an IC50 value of 2 µM.{14589}  

     

    Brand:
    Cayman
    SKU:10007704 - 50 mg

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  • N-(3-pyridyl)-indomethacin amide (N-3PyIA) is one of several aromatic amides of indomethacin reported to be potent and selective reversible inhibitors of COX-2.{8243} N-3PyIA selectively inhibits human recombinant COX-2 with an IC50 of 0.052 µM. It is about 1,300 times less potent as an inhibitor of ovine recombinant COX-1.{8243} However, N-3PyIA is not selective as an inhibitor of ovine seminal vesicular COX-1 and ovine placental COX-2. The IC50 values for ovine COX-1 and -2 are 75 and 50 µM, respectively.{8513}  

     

    Brand:
    Cayman
    SKU:70274 - 1 mg

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  • N-(3-pyridyl)-indomethacin amide (N-3PyIA) is one of several aromatic amides of indomethacin reported to be potent and selective reversible inhibitors of COX-2.{8243} N-3PyIA selectively inhibits human recombinant COX-2 with an IC50 of 0.052 µM. It is about 1,300 times less potent as an inhibitor of ovine recombinant COX-1.{8243} However, N-3PyIA is not selective as an inhibitor of ovine seminal vesicular COX-1 and ovine placental COX-2. The IC50 values for ovine COX-1 and -2 are 75 and 50 µM, respectively.{8513}  

     

    Brand:
    Cayman
    SKU:70274 - 10 mg

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  • N-(3-pyridyl)-indomethacin amide (N-3PyIA) is one of several aromatic amides of indomethacin reported to be potent and selective reversible inhibitors of COX-2.{8243} N-3PyIA selectively inhibits human recombinant COX-2 with an IC50 of 0.052 µM. It is about 1,300 times less potent as an inhibitor of ovine recombinant COX-1.{8243} However, N-3PyIA is not selective as an inhibitor of ovine seminal vesicular COX-1 and ovine placental COX-2. The IC50 values for ovine COX-1 and -2 are 75 and 50 µM, respectively.{8513}  

     

    Brand:
    Cayman
    SKU:70274 - 5 mg

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  • N-(3-pyridyl)-indomethacin amide (N-3PyIA) is one of several aromatic amides of indomethacin reported to be potent and selective reversible inhibitors of COX-2.{8243} N-3PyIA selectively inhibits human recombinant COX-2 with an IC50 of 0.052 µM. It is about 1,300 times less potent as an inhibitor of ovine recombinant COX-1.{8243} However, N-3PyIA is not selective as an inhibitor of ovine seminal vesicular COX-1 and ovine placental COX-2. The IC50 values for ovine COX-1 and -2 are 75 and 50 µM, respectively.{8513}  

     

    Brand:
    Cayman
    SKU:70274 - 50 mg

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  • N-(4-acetamidophenyl)-indomethacin amide (N-4-AIA) is one of several aromatic amides of indomethacin reported to be potent and selective reversible inhibitors of COX-2.{8243} N-4-AIA inhibits human recombinant and ovine COX-2 with IC50 values of 0.12 and 0.625 µM, respectively.{8243,8513} It is about 400 times less potent as an inhibitor of human recombinant COX-1 and 80 times less potent as an inhibitor of ovine COX-1 than ovine COX-2.  

     

    Brand:
    Cayman
    SKU:70278 - 1 mg

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  • N-(4-acetamidophenyl)-indomethacin amide (N-4-AIA) is one of several aromatic amides of indomethacin reported to be potent and selective reversible inhibitors of COX-2.{8243} N-4-AIA inhibits human recombinant and ovine COX-2 with IC50 values of 0.12 and 0.625 µM, respectively.{8243,8513} It is about 400 times less potent as an inhibitor of human recombinant COX-1 and 80 times less potent as an inhibitor of ovine COX-1 than ovine COX-2.  

     

    Brand:
    Cayman
    SKU:70278 - 10 mg

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  • N-(4-acetamidophenyl)-indomethacin amide (N-4-AIA) is one of several aromatic amides of indomethacin reported to be potent and selective reversible inhibitors of COX-2.{8243} N-4-AIA inhibits human recombinant and ovine COX-2 with IC50 values of 0.12 and 0.625 µM, respectively.{8243,8513} It is about 400 times less potent as an inhibitor of human recombinant COX-1 and 80 times less potent as an inhibitor of ovine COX-1 than ovine COX-2.  

     

    Brand:
    Cayman
    SKU:70278 - 5 mg

    Available on backorder

  • N-(4-acetamidophenyl)-indomethacin amide (N-4-AIA) is one of several aromatic amides of indomethacin reported to be potent and selective reversible inhibitors of COX-2.{8243} N-4-AIA inhibits human recombinant and ovine COX-2 with IC50 values of 0.12 and 0.625 µM, respectively.{8243,8513} It is about 400 times less potent as an inhibitor of human recombinant COX-1 and 80 times less potent as an inhibitor of ovine COX-1 than ovine COX-2.  

     

    Brand:
    Cayman
    SKU:70278 - 50 mg

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  • N-(8Z-Heptadecen-1-yl)-O-(3-pyridylmethyl)carbamate is a synthetic analog of the long-chain fatty acid amides (macamides or macaenes) isolated from the maca (L. meyenii) plant, which are structurally related to cannabinoids.{28386} Nineteen macamides have currently been identified and many are recognized as potent inhibitors of fatty acid amide hydrolase (FAAH) and demonstrate selective antiproliferative activity against diverse cancer cell lines.{28386,28387} N-(8Z-Heptadecen-1-yl)-O-(3-pyridylmethyl)carbamate irreversibly inhibits FAAH with an IC50 value of 0.153 µM.{28386}  

     

    Brand:
    Cayman
    SKU:9002365 - 10 mg

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  • N-(8Z-Heptadecen-1-yl)-O-(3-pyridylmethyl)carbamate is a synthetic analog of the long-chain fatty acid amides (macamides or macaenes) isolated from the maca (L. meyenii) plant, which are structurally related to cannabinoids.{28386} Nineteen macamides have currently been identified and many are recognized as potent inhibitors of fatty acid amide hydrolase (FAAH) and demonstrate selective antiproliferative activity against diverse cancer cell lines.{28386,28387} N-(8Z-Heptadecen-1-yl)-O-(3-pyridylmethyl)carbamate irreversibly inhibits FAAH with an IC50 value of 0.153 µM.{28386}  

     

    Brand:
    Cayman
    SKU:9002365 - 100 mg

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  • N-(8Z-Heptadecen-1-yl)-O-(3-pyridylmethyl)carbamate is a synthetic analog of the long-chain fatty acid amides (macamides or macaenes) isolated from the maca (L. meyenii) plant, which are structurally related to cannabinoids.{28386} Nineteen macamides have currently been identified and many are recognized as potent inhibitors of fatty acid amide hydrolase (FAAH) and demonstrate selective antiproliferative activity against diverse cancer cell lines.{28386,28387} N-(8Z-Heptadecen-1-yl)-O-(3-pyridylmethyl)carbamate irreversibly inhibits FAAH with an IC50 value of 0.153 µM.{28386}  

     

    Brand:
    Cayman
    SKU:9002365 - 250 mg

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  • N-(8Z-Heptadecen-1-yl)-O-(3-pyridylmethyl)carbamate is a synthetic analog of the long-chain fatty acid amides (macamides or macaenes) isolated from the maca (L. meyenii) plant, which are structurally related to cannabinoids.{28386} Nineteen macamides have currently been identified and many are recognized as potent inhibitors of fatty acid amide hydrolase (FAAH) and demonstrate selective antiproliferative activity against diverse cancer cell lines.{28386,28387} N-(8Z-Heptadecen-1-yl)-O-(3-pyridylmethyl)carbamate irreversibly inhibits FAAH with an IC50 value of 0.153 µM.{28386}  

     

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    Cayman
    SKU:9002365 - 50 mg

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  • N-(diphenylmethylene) Glycine benzyl ester is a synthetic intermediate useful for pharmaceutical synthesis.  

     

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    Cayman
    SKU:10007089 - 1 g

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  • N-(diphenylmethylene) Glycine benzyl ester is a synthetic intermediate useful for pharmaceutical synthesis.  

     

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    Cayman
    SKU:10007089 - 10 g

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  • N-(diphenylmethylene) Glycine benzyl ester is a synthetic intermediate useful for pharmaceutical synthesis.  

     

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    Cayman
    SKU:10007089 - 5 g

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  • N-(diphenylmethylene) Glycine benzyl ester is a synthetic intermediate useful for pharmaceutical synthesis.  

     

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    Cayman
    SKU:10007089 - 500 mg

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  • N-(n-Butyl)deoxygalactonojirimycin (NB-DGJ) is an inhibitor of the glycolipid biosynthesis enzyme glucosylceramide synthase and the glycolipid catabolic enzymes glucocerebrosidase (GBA) and β-glucosidase 2 (GBA2).{31624,49490,49491,49492,50926} It also inhibits acid α-glucosidase, sucrase, maltase, and lactase.{49492} NB-DGJ (0.5-500 µM) reduces glycolipid levels in HL-60 and WEHI-3B cells.{31624} It decreases brain ganglioside levels in a Glb1-/- neonatal mouse model of GM1 gangliosidosis when administered intraperitoneally at doses of 600 and 1,200 mg/kg four times per day for three days.{31622} NB-DGJ (1-1,200 mg/kg per day for 35 days) increases testicular glucosylceramide levels in mice.{49490} NB-DGJ induces abnormal spermatid and acrosome formation, as well as reduces motility, in isolated mouse epididymal sperm when administered at doses of 15, 25, and 50 mg/kg per day.{50926} It also induces infertility, an effect that is reversed by withdrawal, in the same model.  

     

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  • N-(n-Butyl)deoxygalactonojirimycin (NB-DGJ) is an inhibitor of the glycolipid biosynthesis enzyme glucosylceramide synthase and the glycolipid catabolic enzymes glucocerebrosidase (GBA) and β-glucosidase 2 (GBA2).{31624,49490,49491,49492,50926} It also inhibits acid α-glucosidase, sucrase, maltase, and lactase.{49492} NB-DGJ (0.5-500 µM) reduces glycolipid levels in HL-60 and WEHI-3B cells.{31624} It decreases brain ganglioside levels in a Glb1-/- neonatal mouse model of GM1 gangliosidosis when administered intraperitoneally at doses of 600 and 1,200 mg/kg four times per day for three days.{31622} NB-DGJ (1-1,200 mg/kg per day for 35 days) increases testicular glucosylceramide levels in mice.{49490} NB-DGJ induces abnormal spermatid and acrosome formation, as well as reduces motility, in isolated mouse epididymal sperm when administered at doses of 15, 25, and 50 mg/kg per day.{50926} It also induces infertility, an effect that is reversed by withdrawal, in the same model.  

     

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  • N-(n-Butyl)deoxygalactonojirimycin (NB-DGJ) is an inhibitor of the glycolipid biosynthesis enzyme glucosylceramide synthase and the glycolipid catabolic enzymes glucocerebrosidase (GBA) and β-glucosidase 2 (GBA2).{31624,49490,49491,49492,50926} It also inhibits acid α-glucosidase, sucrase, maltase, and lactase.{49492} NB-DGJ (0.5-500 µM) reduces glycolipid levels in HL-60 and WEHI-3B cells.{31624} It decreases brain ganglioside levels in a Glb1-/- neonatal mouse model of GM1 gangliosidosis when administered intraperitoneally at doses of 600 and 1,200 mg/kg four times per day for three days.{31622} NB-DGJ (1-1,200 mg/kg per day for 35 days) increases testicular glucosylceramide levels in mice.{49490} NB-DGJ induces abnormal spermatid and acrosome formation, as well as reduces motility, in isolated mouse epididymal sperm when administered at doses of 15, 25, and 50 mg/kg per day.{50926} It also induces infertility, an effect that is reversed by withdrawal, in the same model.  

     

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  • N-(p-amylcinnamoyl) Anthranilic acid (ACA) is a channel blocker that acts on several transient receptor potential (TRP) channels, including TRPM2, TRPM8, and TRPC6 (IC50 = 1.7, 3.8, and 2.3 μM, respectively).{24045,24047} It is a weak inhibitor of TRPV1.{24047} ACA is also an inhibitor of phospholipase A2, blocking the release of arachidonic acid when given at 50 μM.{24044,24046}  

     

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  • N-(p-amylcinnamoyl) Anthranilic acid (ACA) is a channel blocker that acts on several transient receptor potential (TRP) channels, including TRPM2, TRPM8, and TRPC6 (IC50 = 1.7, 3.8, and 2.3 μM, respectively).{24045,24047} It is a weak inhibitor of TRPV1.{24047} ACA is also an inhibitor of phospholipase A2, blocking the release of arachidonic acid when given at 50 μM.{24044,24046}  

     

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    Cayman
    SKU:-
  • N-(p-amylcinnamoyl) Anthranilic acid (ACA) is a channel blocker that acts on several transient receptor potential (TRP) channels, including TRPM2, TRPM8, and TRPC6 (IC50 = 1.7, 3.8, and 2.3 μM, respectively).{24045,24047} It is a weak inhibitor of TRPV1.{24047} ACA is also an inhibitor of phospholipase A2, blocking the release of arachidonic acid when given at 50 μM.{24044,24046}  

     

    Brand:
    Cayman
    SKU:-
  • N-(p-amylcinnamoyl) Anthranilic acid (ACA) is a channel blocker that acts on several transient receptor potential (TRP) channels, including TRPM2, TRPM8, and TRPC6 (IC50 = 1.7, 3.8, and 2.3 μM, respectively).{24045,24047} It is a weak inhibitor of TRPV1.{24047} ACA is also an inhibitor of phospholipase A2, blocking the release of arachidonic acid when given at 50 μM.{24044,24046}  

     

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  • N-(p-Coumaroyl) serotonin is an antioxidative phenolic naturally found in plants, including safflower seed and millet grain.{29000,29005} It ameliorates atherosclerosis in vivo, reducing lesion area in mice and rabbits.{29000,29002} N-(p-Coumaroyl) serotonin also suppresses inflammatory cytokine generation by human monocytes, augments fibroblast proliferation, and promotes relaxation of vascular smooth muscle cells in vitro.{29001,29003,29004}  

     

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    Cayman
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  • N-(p-Coumaroyl) serotonin is an antioxidative phenolic naturally found in plants, including safflower seed and millet grain.{29000,29005} It ameliorates atherosclerosis in vivo, reducing lesion area in mice and rabbits.{29000,29002} N-(p-Coumaroyl) serotonin also suppresses inflammatory cytokine generation by human monocytes, augments fibroblast proliferation, and promotes relaxation of vascular smooth muscle cells in vitro.{29001,29003,29004}  

     

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  • N-(p-Coumaroyl) serotonin is an antioxidative phenolic naturally found in plants, including safflower seed and millet grain.{29000,29005} It ameliorates atherosclerosis in vivo, reducing lesion area in mice and rabbits.{29000,29002} N-(p-Coumaroyl) serotonin also suppresses inflammatory cytokine generation by human monocytes, augments fibroblast proliferation, and promotes relaxation of vascular smooth muscle cells in vitro.{29001,29003,29004}  

     

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    Cayman
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  • N-(p-Coumaroyl) serotonin is an antioxidative phenolic naturally found in plants, including safflower seed and millet grain.{29000,29005} It ameliorates atherosclerosis in vivo, reducing lesion area in mice and rabbits.{29000,29002} N-(p-Coumaroyl) serotonin also suppresses inflammatory cytokine generation by human monocytes, augments fibroblast proliferation, and promotes relaxation of vascular smooth muscle cells in vitro.{29001,29003,29004}  

     

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  • N-(p-Tosyl)-GPR-pNA is a colorimetric substrate for thrombin.{48594} Thrombin preferentially binds to and cleaves the Gly-Pro-Arg (GPR) peptide sequence to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of thrombin activity.  

     

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    SKU:27568 - 100 mg

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  • N-(p-Tosyl)-GPR-pNA is a colorimetric substrate for thrombin.{48594} Thrombin preferentially binds to and cleaves the Gly-Pro-Arg (GPR) peptide sequence to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of thrombin activity.  

     

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    SKU:27568 - 25 mg

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  • N-(p-Tosyl)-GPR-pNA is a colorimetric substrate for thrombin.{48594} Thrombin preferentially binds to and cleaves the Gly-Pro-Arg (GPR) peptide sequence to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of thrombin activity.  

     

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    SKU:27568 - 250 mg

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  • N-(p-Tosyl)-GPR-pNA is a colorimetric substrate for thrombin.{48594} Thrombin preferentially binds to and cleaves the Gly-Pro-Arg (GPR) peptide sequence to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of thrombin activity.  

     

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    Cayman
    SKU:27568 - 50 mg

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  • Certain chronic neurologic disorders, such as Parkinson’s disease, are caused by an insufficiency of the neurotransmitter dopamine secondary to the degeneration of substantia nigra dopaminergic neurons.{7161} N-(α-Linolenoyl) tyrosine (NALT) is a simple α-amide conjugate between the ω-3 essential fatty acid α-linolenate and the amino acid tyrosine. α-Linolenate is an important precursor to docosahexaenoic acid (DHA), a prominent brain polyunsaturated fatty acid, while tyrosine is the metabolic precursor for neuronal dopamine synthesis. NALT was prepared as a method for enhancing central nervous system (CNS) dopamine content by facilitated transport of the tyrosine precursor across the blood-brain barrier.{10323} In experimental rat models of dopamine insufficiency, NALT increased CNS dopamine levels and exhibited an activity profile consistent with an anti-Parkinson’s therapeutic agent.{10323}  

     

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    Cayman
    SKU:10032 - 10 mg

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  • Certain chronic neurologic disorders, such as Parkinson’s disease, are caused by an insufficiency of the neurotransmitter dopamine secondary to the degeneration of substantia nigra dopaminergic neurons.{7161} N-(α-Linolenoyl) tyrosine (NALT) is a simple α-amide conjugate between the ω-3 essential fatty acid α-linolenate and the amino acid tyrosine. α-Linolenate is an important precursor to docosahexaenoic acid (DHA), a prominent brain polyunsaturated fatty acid, while tyrosine is the metabolic precursor for neuronal dopamine synthesis. NALT was prepared as a method for enhancing central nervous system (CNS) dopamine content by facilitated transport of the tyrosine precursor across the blood-brain barrier.{10323} In experimental rat models of dopamine insufficiency, NALT increased CNS dopamine levels and exhibited an activity profile consistent with an anti-Parkinson’s therapeutic agent.{10323}  

     

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    Cayman
    SKU:10032 - 100 mg

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  • Certain chronic neurologic disorders, such as Parkinson’s disease, are caused by an insufficiency of the neurotransmitter dopamine secondary to the degeneration of substantia nigra dopaminergic neurons.{7161} N-(α-Linolenoyl) tyrosine (NALT) is a simple α-amide conjugate between the ω-3 essential fatty acid α-linolenate and the amino acid tyrosine. α-Linolenate is an important precursor to docosahexaenoic acid (DHA), a prominent brain polyunsaturated fatty acid, while tyrosine is the metabolic precursor for neuronal dopamine synthesis. NALT was prepared as a method for enhancing central nervous system (CNS) dopamine content by facilitated transport of the tyrosine precursor across the blood-brain barrier.{10323} In experimental rat models of dopamine insufficiency, NALT increased CNS dopamine levels and exhibited an activity profile consistent with an anti-Parkinson’s therapeutic agent.{10323}  

     

    Brand:
    Cayman
    SKU:10032 - 5 mg

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  • Certain chronic neurologic disorders, such as Parkinson’s disease, are caused by an insufficiency of the neurotransmitter dopamine secondary to the degeneration of substantia nigra dopaminergic neurons.{7161} N-(α-Linolenoyl) tyrosine (NALT) is a simple α-amide conjugate between the ω-3 essential fatty acid α-linolenate and the amino acid tyrosine. α-Linolenate is an important precursor to docosahexaenoic acid (DHA), a prominent brain polyunsaturated fatty acid, while tyrosine is the metabolic precursor for neuronal dopamine synthesis. NALT was prepared as a method for enhancing central nervous system (CNS) dopamine content by facilitated transport of the tyrosine precursor across the blood-brain barrier.{10323} In experimental rat models of dopamine insufficiency, NALT increased CNS dopamine levels and exhibited an activity profile consistent with an anti-Parkinson’s therapeutic agent.{10323}  

     

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    Cayman
    SKU:10032 - 50 mg

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  • Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density.{15370} This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production.{13434} Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which generally consists of a fatty acid coupled with homoserine lactone (HSL). Regulation of bacterial quorum sensing signaling systems to inhibit pathogenesis represents a new approach to antimicrobial therapy in the treatment of infectious diseases.{15369} AHLs vary in acyl group length (C4-C18), in the substitution of C3 (hydrogen, hydroxyl, or oxo group), and in the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signal specificity through the affinity of transcriptional regulators of the LuxR family.{15398} In one of the most-studied quorum-sensing systems in gram-negative bacteria, the LuxI AHL synthase catalyzes the production of N-(β-ketocaproyl)-L-homoserine lactone utilizing S-adenosylmethionine and hexanoyl-acyl carrier protein as reaction substrates in the marine bioluminescence bacterium V. fischeri.{16881} At increased populations of the bacteria, localized higher concentrations of 3-O-C6-HSL, an endogenous ligand to transcriptional factor LuxR, leads to increased production of both the AHL synthase and proteins responsible for bioluminescence.{15370} Numerous other species of bacteria also employ N-(β-ketocaproyl)-L-homoserine lactone in cell-to-cell communication.{16800,15932,16767,15399}  

     

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    Cayman
    SKU:10011207 - 10 mg

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  • Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density.{15370} This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production.{13434} Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which generally consists of a fatty acid coupled with homoserine lactone (HSL). Regulation of bacterial quorum sensing signaling systems to inhibit pathogenesis represents a new approach to antimicrobial therapy in the treatment of infectious diseases.{15369} AHLs vary in acyl group length (C4-C18), in the substitution of C3 (hydrogen, hydroxyl, or oxo group), and in the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signal specificity through the affinity of transcriptional regulators of the LuxR family.{15398} In one of the most-studied quorum-sensing systems in gram-negative bacteria, the LuxI AHL synthase catalyzes the production of N-(β-ketocaproyl)-L-homoserine lactone utilizing S-adenosylmethionine and hexanoyl-acyl carrier protein as reaction substrates in the marine bioluminescence bacterium V. fischeri.{16881} At increased populations of the bacteria, localized higher concentrations of 3-O-C6-HSL, an endogenous ligand to transcriptional factor LuxR, leads to increased production of both the AHL synthase and proteins responsible for bioluminescence.{15370} Numerous other species of bacteria also employ N-(β-ketocaproyl)-L-homoserine lactone in cell-to-cell communication.{16800,15932,16767,15399}  

     

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    Cayman
    SKU:10011207 - 25 mg

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  • Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density.{15370} This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production.{13434} Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which generally consists of a fatty acid coupled with homoserine lactone (HSL). Regulation of bacterial quorum sensing signaling systems to inhibit pathogenesis represents a new approach to antimicrobial therapy in the treatment of infectious diseases.{15369} AHLs vary in acyl group length (C4-C18), in the substitution of C3 (hydrogen, hydroxyl, or oxo group), and in the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signal specificity through the affinity of transcriptional regulators of the LuxR family.{15398} In one of the most-studied quorum-sensing systems in gram-negative bacteria, the LuxI AHL synthase catalyzes the production of N-(β-ketocaproyl)-L-homoserine lactone utilizing S-adenosylmethionine and hexanoyl-acyl carrier protein as reaction substrates in the marine bioluminescence bacterium V. fischeri.{16881} At increased populations of the bacteria, localized higher concentrations of 3-O-C6-HSL, an endogenous ligand to transcriptional factor LuxR, leads to increased production of both the AHL synthase and proteins responsible for bioluminescence.{15370} Numerous other species of bacteria also employ N-(β-ketocaproyl)-L-homoserine lactone in cell-to-cell communication.{16800,15932,16767,15399}  

     

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    Cayman
    SKU:10011207 - 5 mg

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  • Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density.{15370} This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production.{13434} Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which generally consists of a fatty acid coupled with homoserine lactone (HSL). Regulation of bacterial quorum sensing signaling systems to inhibit pathogenesis represents a new approach to antimicrobial therapy in the treatment of infectious diseases.{15369} AHLs vary in acyl group length (C4-C18), in the substitution of C3 (hydrogen, hydroxyl, or oxo group), and in the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signal specificity through the affinity of transcriptional regulators of the LuxR family.{15398} In one of the most-studied quorum-sensing systems in gram-negative bacteria, the LuxI AHL synthase catalyzes the production of N-(β-ketocaproyl)-L-homoserine lactone utilizing S-adenosylmethionine and hexanoyl-acyl carrier protein as reaction substrates in the marine bioluminescence bacterium V. fischeri.{16881} At increased populations of the bacteria, localized higher concentrations of 3-O-C6-HSL, an endogenous ligand to transcriptional factor LuxR, leads to increased production of both the AHL synthase and proteins responsible for bioluminescence.{15370} Numerous other species of bacteria also employ N-(β-ketocaproyl)-L-homoserine lactone in cell-to-cell communication.{16800,15932,16767,15399}  

     

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    SKU:10011207 - 50 mg

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  • N-[(3-(Anilinomethylene)-2-chloro-1-cyclohexen-1-yl)methylene]aniline is a building block.{53717,53718} It has been used in the synthesis of various cyanine-containing dyes.  

     

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    SKU:30560 - 1 g

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  • N-[(3-(Anilinomethylene)-2-chloro-1-cyclohexen-1-yl)methylene]aniline is a building block.{53717,53718} It has been used in the synthesis of various cyanine-containing dyes.  

     

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    SKU:30560 - 5 g

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  • N-[(3-(Anilinomethylene)-2-chloro-1-cyclohexen-1-yl)methylene]aniline is a building block.{53717,53718} It has been used in the synthesis of various cyanine-containing dyes.  

     

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    SKU:30560 - 500 mg

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  • N-[1-(2,3-Dioleyloxy)propyl]-N,N,N-trimethylammonium (DOTMA) is a cationic lipid.{43501} It has been used as a component in liposomes that can be used to encapsulate siRNA, microRNAs, and oligonucleotides and for gene transfection in vitro.{43501,43502}  

     

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    SKU:25926 - 10 mg

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  • N-[1-(2,3-Dioleyloxy)propyl]-N,N,N-trimethylammonium (DOTMA) is a cationic lipid.{43501} It has been used as a component in liposomes that can be used to encapsulate siRNA, microRNAs, and oligonucleotides and for gene transfection in vitro.{43501,43502}  

     

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    Cayman
    SKU:25926 - 25 mg

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  • N-[1-(2,3-Dioleyloxy)propyl]-N,N,N-trimethylammonium (DOTMA) is a cationic lipid.{43501} It has been used as a component in liposomes that can be used to encapsulate siRNA, microRNAs, and oligonucleotides and for gene transfection in vitro.{43501,43502}  

     

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    Cayman
    SKU:25926 - 5 mg

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  • N-[1-(2,3-Dioleyloxy)propyl]-N,N,N-trimethylammonium (DOTMA) is a cationic lipid.{43501} It has been used as a component in liposomes that can be used to encapsulate siRNA, microRNAs, and oligonucleotides and for gene transfection in vitro.{43501,43502}  

     

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    SKU:25926 - 50 mg

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  • N-3-hydroxybutyryl-L-Homoserine lactone is an N-acyl-homoserine lactone produced by the bacterium V. splendidus and has been found in sequencing batch biofilm reactors used in wastewater treatment.{53431,53432} It is the racemic version of the V. harveyi autoinducer N-((R)-3-hydroxybutanoyl)-L-homoserine lactone.{53433}  

     

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    SKU:27691 - 1 mg

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  • N-3-hydroxybutyryl-L-Homoserine lactone is an N-acyl-homoserine lactone produced by the bacterium V. splendidus and has been found in sequencing batch biofilm reactors used in wastewater treatment.{53431,53432} It is the racemic version of the V. harveyi autoinducer N-((R)-3-hydroxybutanoyl)-L-homoserine lactone.{53433}  

     

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    SKU:27691 - 10 mg

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  • N-3-hydroxybutyryl-L-Homoserine lactone is an N-acyl-homoserine lactone produced by the bacterium V. splendidus and has been found in sequencing batch biofilm reactors used in wastewater treatment.{53431,53432} It is the racemic version of the V. harveyi autoinducer N-((R)-3-hydroxybutanoyl)-L-homoserine lactone.{53433}  

     

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    Cayman
    SKU:27691 - 5 mg

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  • Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. Different quorum sensing molecules are produced at different times in bacterial population growth and have distinct cellular effects mediated through changes in gene expression.{16591,16592} N-3-hydroxydecanoyl-L-Homoserine lactone is a small diffusible signaling molecule secreted by various bacteria.{20837,20834} This lactone is produced via lactonolysis from 3-oxodecanoyl-homoserine lactone, altering quorum sensing or contributing to quorum quenching.{20832}  

     

    Brand:
    Cayman
    SKU:9001147 - 1 mg

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  • Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. Different quorum sensing molecules are produced at different times in bacterial population growth and have distinct cellular effects mediated through changes in gene expression.{16591,16592} N-3-hydroxydecanoyl-L-Homoserine lactone is a small diffusible signaling molecule secreted by various bacteria.{20837,20834} This lactone is produced via lactonolysis from 3-oxodecanoyl-homoserine lactone, altering quorum sensing or contributing to quorum quenching.{20832}  

     

    Brand:
    Cayman
    SKU:9001147 - 10 mg

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  • Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. Different quorum sensing molecules are produced at different times in bacterial population growth and have distinct cellular effects mediated through changes in gene expression.{16591,16592} N-3-hydroxydecanoyl-L-Homoserine lactone is a small diffusible signaling molecule secreted by various bacteria.{20837,20834} This lactone is produced via lactonolysis from 3-oxodecanoyl-homoserine lactone, altering quorum sensing or contributing to quorum quenching.{20832}  

     

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    Cayman
    SKU:9001147 - 5 mg

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  • Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. Different quorum sensing molecules are produced at different times in bacterial population growth and have distinct cellular effects mediated through changes in gene expression.{16591,16592} N-3-hydroxyoctanoyl-L-Homoserine lactone is a small diffusible signaling molecule secreted by various bacteria.{20835,20837} This lactone can have activating or suppressing effects on gene expression and biofilm formation, respectively.{20833,20836} N-3-hydroxyoctanoyl-L-Homoserine lactone is produced via lactonolysis from 3-oxooctanoyl-homoserine lactone, altering quorum sensing or contributing to quorum quenching.{20832}  

     

    Brand:
    Cayman
    SKU:9001150 - 1 mg

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  • Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. Different quorum sensing molecules are produced at different times in bacterial population growth and have distinct cellular effects mediated through changes in gene expression.{16591,16592} N-3-hydroxyoctanoyl-L-Homoserine lactone is a small diffusible signaling molecule secreted by various bacteria.{20835,20837} This lactone can have activating or suppressing effects on gene expression and biofilm formation, respectively.{20833,20836} N-3-hydroxyoctanoyl-L-Homoserine lactone is produced via lactonolysis from 3-oxooctanoyl-homoserine lactone, altering quorum sensing or contributing to quorum quenching.{20832}  

     

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    Cayman
    SKU:9001150 - 10 mg

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