Chemicals
Showing 19651–19800 of 41137 results
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Flavoxate blocks L-type calcium (Cav1.2) channels and acts an antagonist of muscarinic acetylcholine receptors. Through these actions, flavoxate inhibits contraction of detrusor myocytes and prevents activation of the micturition center in the brain, resulting in muscle relaxation (IC50 = 2 µM for relaxation of human bladder precontracted by K+).{30978} Flavoxate has been studied clinically for the management of overactive bladder, for its potential to relax urinary bladder smooth muscle in order to suppress the micturition reflex.{30978}
Brand:CaymanSKU:-Available on backorder
Flecainide is an inhibitor of cardiac late sodium current (INa; IC50 = 3.4 µM) and delayed-rectifier potassium current (IKr; IC50 = 1.5 µM).{32107,30900,29898} Formulations containing flecainide have been used in the treatment of arrhythmias and sodium-dependent calcium overload associated with myocardial ischemia and heart failure.
Brand:CaymanSKU:20388 -Available on backorder
Flecainide is an inhibitor of cardiac late sodium current (INa; IC50 = 3.4 µM) and delayed-rectifier potassium current (IKr; IC50 = 1.5 µM).{32107,30900,29898} Formulations containing flecainide have been used in the treatment of arrhythmias and sodium-dependent calcium overload associated with myocardial ischemia and heart failure.
Brand:CaymanSKU:20388 -Available on backorder
Flecainide is an inhibitor of cardiac late sodium current (INa; IC50 = 3.4 µM) and delayed-rectifier potassium current (IKr; IC50 = 1.5 µM).{32107,30900,29898} Formulations containing flecainide have been used in the treatment of arrhythmias and sodium-dependent calcium overload associated with myocardial ischemia and heart failure.
Brand:CaymanSKU:20388 -Available on backorder
Flecainide is an inhibitor of cardiac late sodium current (INa; IC50 = 3.4 µM) and delayed-rectifier potassium current (IKr; IC50 = 1.5 µM).{32107,30900,29898} Formulations containing flecainide have been used in the treatment of arrhythmias and sodium-dependent calcium overload associated with myocardial ischemia and heart failure.
Brand:CaymanSKU:20388 -Available on backorder
Fleroxacin is a broad-spectrum fluoroquinolone antibiotic.{38988} It is active against a variety of Gram-positive and Gram-negative bacteria with MIC90 values ranging from 0.05 to 3.13 µg/ml for clinical isolates of Staphylococcus, P. aeruginosa, H. influenzae, N. gonorrhoeae, B. catarrhalis, C. jejuni, and various species of Enterobacteriaceae. Fleroxacin inhibits bacterial DNA replication with IC50 values of 82.6 and 31.6 µg/ml for S. aureus DNA gyrase and topoisomerase IV, respectively.{27493} Fleroxacin is active in vivo with ED50 values ranging from 0.8 to 16.6 mg/kg in mice with systemic bacterial infections.{38988} It also reduces E. coli in the kidney in a mouse model of urinary tract infection when administered at doses of 0.625 and 10 mg/kg twice daily. Formulations containing fleroxacin have been used in the treatment of uncomplicated cystitis, gonorrhea, bacterial enteritis, traveler’s diarrhea, and urinary tract infections.{38989}
Brand:CaymanSKU:24173 - 1 gAvailable on backorder
Fleroxacin is a broad-spectrum fluoroquinolone antibiotic.{38988} It is active against a variety of Gram-positive and Gram-negative bacteria with MIC90 values ranging from 0.05 to 3.13 µg/ml for clinical isolates of Staphylococcus, P. aeruginosa, H. influenzae, N. gonorrhoeae, B. catarrhalis, C. jejuni, and various species of Enterobacteriaceae. Fleroxacin inhibits bacterial DNA replication with IC50 values of 82.6 and 31.6 µg/ml for S. aureus DNA gyrase and topoisomerase IV, respectively.{27493} Fleroxacin is active in vivo with ED50 values ranging from 0.8 to 16.6 mg/kg in mice with systemic bacterial infections.{38988} It also reduces E. coli in the kidney in a mouse model of urinary tract infection when administered at doses of 0.625 and 10 mg/kg twice daily. Formulations containing fleroxacin have been used in the treatment of uncomplicated cystitis, gonorrhea, bacterial enteritis, traveler’s diarrhea, and urinary tract infections.{38989}
Brand:CaymanSKU:24173 - 10 gAvailable on backorder
Fleroxacin is a broad-spectrum fluoroquinolone antibiotic.{38988} It is active against a variety of Gram-positive and Gram-negative bacteria with MIC90 values ranging from 0.05 to 3.13 µg/ml for clinical isolates of Staphylococcus, P. aeruginosa, H. influenzae, N. gonorrhoeae, B. catarrhalis, C. jejuni, and various species of Enterobacteriaceae. Fleroxacin inhibits bacterial DNA replication with IC50 values of 82.6 and 31.6 µg/ml for S. aureus DNA gyrase and topoisomerase IV, respectively.{27493} Fleroxacin is active in vivo with ED50 values ranging from 0.8 to 16.6 mg/kg in mice with systemic bacterial infections.{38988} It also reduces E. coli in the kidney in a mouse model of urinary tract infection when administered at doses of 0.625 and 10 mg/kg twice daily. Formulations containing fleroxacin have been used in the treatment of uncomplicated cystitis, gonorrhea, bacterial enteritis, traveler’s diarrhea, and urinary tract infections.{38989}
Brand:CaymanSKU:24173 - 25 gAvailable on backorder
Fleroxacin is a broad-spectrum fluoroquinolone antibiotic.{38988} It is active against a variety of Gram-positive and Gram-negative bacteria with MIC90 values ranging from 0.05 to 3.13 µg/ml for clinical isolates of Staphylococcus, P. aeruginosa, H. influenzae, N. gonorrhoeae, B. catarrhalis, C. jejuni, and various species of Enterobacteriaceae. Fleroxacin inhibits bacterial DNA replication with IC50 values of 82.6 and 31.6 µg/ml for S. aureus DNA gyrase and topoisomerase IV, respectively.{27493} Fleroxacin is active in vivo with ED50 values ranging from 0.8 to 16.6 mg/kg in mice with systemic bacterial infections.{38988} It also reduces E. coli in the kidney in a mouse model of urinary tract infection when administered at doses of 0.625 and 10 mg/kg twice daily. Formulations containing fleroxacin have been used in the treatment of uncomplicated cystitis, gonorrhea, bacterial enteritis, traveler’s diarrhea, and urinary tract infections.{38989}
Brand:CaymanSKU:24173 - 5 gAvailable on backorder
FLI-06 is a first-of-its-kind inhibitor of Notch signaling (EC50 = 2.3 µM) that acts upstream of α-secretase and β-secretase cleavage.{33469} It disrupts the intracellular trafficking and processing of the Notch signaling pathway, inhibiting general secretion at a stage before exit from the endoplasmic reticulum (ER) and converting ER morphology from tubule to sheet.{33469} FLI-06 is reported to alter the maturation pattern of amyloid precursor protein (APP) and prevent the shedding of APPs in HEK293 cells stably expressing a mutated APP that yields robust amounts of amyloid β.{33469}
Brand:CaymanSKU:21272 -Out of stock
FLI-06 is a first-of-its-kind inhibitor of Notch signaling (EC50 = 2.3 µM) that acts upstream of α-secretase and β-secretase cleavage.{33469} It disrupts the intracellular trafficking and processing of the Notch signaling pathway, inhibiting general secretion at a stage before exit from the endoplasmic reticulum (ER) and converting ER morphology from tubule to sheet.{33469} FLI-06 is reported to alter the maturation pattern of amyloid precursor protein (APP) and prevent the shedding of APPs in HEK293 cells stably expressing a mutated APP that yields robust amounts of amyloid β.{33469}
Brand:CaymanSKU:21272 -Out of stock
FLI-06 is a first-of-its-kind inhibitor of Notch signaling (EC50 = 2.3 µM) that acts upstream of α-secretase and β-secretase cleavage.{33469} It disrupts the intracellular trafficking and processing of the Notch signaling pathway, inhibiting general secretion at a stage before exit from the endoplasmic reticulum (ER) and converting ER morphology from tubule to sheet.{33469} FLI-06 is reported to alter the maturation pattern of amyloid precursor protein (APP) and prevent the shedding of APPs in HEK293 cells stably expressing a mutated APP that yields robust amounts of amyloid β.{33469}
Brand:CaymanSKU:21272 -Out of stock
FLI-06 is a first-of-its-kind inhibitor of Notch signaling (EC50 = 2.3 µM) that acts upstream of α-secretase and β-secretase cleavage.{33469} It disrupts the intracellular trafficking and processing of the Notch signaling pathway, inhibiting general secretion at a stage before exit from the endoplasmic reticulum (ER) and converting ER morphology from tubule to sheet.{33469} FLI-06 is reported to alter the maturation pattern of amyloid precursor protein (APP) and prevent the shedding of APPs in HEK293 cells stably expressing a mutated APP that yields robust amounts of amyloid β.{33469}
Brand:CaymanSKU:21272 -Out of stock
Flibanserin is a full agonist of the serotonin 5-HT1A receptor and an antagonist of 5-HT2A (Kis = 1 and 49 nM, respectively).{31001} It also binds to dopamine D4 receptors with Ki values ranging from 4-24 nM, but demonstrates no affinity for the other 5-HT subtypes or other neurotransmitter receptors.{31001} In vitro, flibanserin has been shown to reduce forskolin-stimulated cAMP formation in cells and rat tissues and to antagonize the accumulation of phosphatidyl inositol turnover induced by 5-HT in the mouse cortex.{31001} At 10 mg/kg, flibanserin can reduce serotonin in the prefrontal cortex and dorsal raphe of conscious rats while increasing extracellular noradrenaline and dopamine.{31001} Multifunctional serotonergic ligands like flibanserin that can enhance downstream release of dopamine and norepinephrine while concomitantly reducing serotonin release in the brain circuits that mediate symptoms of reduced sexual interest and desire are being studied clinically for therapeutic potential to improve sexual functioning.{31002}
Brand:CaymanSKU:-Available on backorder
Flibanserin is a full agonist of the serotonin 5-HT1A receptor and an antagonist of 5-HT2A (Kis = 1 and 49 nM, respectively).{31001} It also binds to dopamine D4 receptors with Ki values ranging from 4-24 nM, but demonstrates no affinity for the other 5-HT subtypes or other neurotransmitter receptors.{31001} In vitro, flibanserin has been shown to reduce forskolin-stimulated cAMP formation in cells and rat tissues and to antagonize the accumulation of phosphatidyl inositol turnover induced by 5-HT in the mouse cortex.{31001} At 10 mg/kg, flibanserin can reduce serotonin in the prefrontal cortex and dorsal raphe of conscious rats while increasing extracellular noradrenaline and dopamine.{31001} Multifunctional serotonergic ligands like flibanserin that can enhance downstream release of dopamine and norepinephrine while concomitantly reducing serotonin release in the brain circuits that mediate symptoms of reduced sexual interest and desire are being studied clinically for therapeutic potential to improve sexual functioning.{31002}
Brand:CaymanSKU:-Available on backorder
Flibanserin is a full agonist of the serotonin 5-HT1A receptor and an antagonist of 5-HT2A (Kis = 1 and 49 nM, respectively).{31001} It also binds to dopamine D4 receptors with Ki values ranging from 4-24 nM, but demonstrates no affinity for the other 5-HT subtypes or other neurotransmitter receptors.{31001} In vitro, flibanserin has been shown to reduce forskolin-stimulated cAMP formation in cells and rat tissues and to antagonize the accumulation of phosphatidyl inositol turnover induced by 5-HT in the mouse cortex.{31001} At 10 mg/kg, flibanserin can reduce serotonin in the prefrontal cortex and dorsal raphe of conscious rats while increasing extracellular noradrenaline and dopamine.{31001} Multifunctional serotonergic ligands like flibanserin that can enhance downstream release of dopamine and norepinephrine while concomitantly reducing serotonin release in the brain circuits that mediate symptoms of reduced sexual interest and desire are being studied clinically for therapeutic potential to improve sexual functioning.{31002}
Brand:CaymanSKU:-Available on backorder
Flibanserin is a full agonist of the serotonin 5-HT1A receptor and an antagonist of 5-HT2A (Kis = 1 and 49 nM, respectively).{31001} It also binds to dopamine D4 receptors with Ki values ranging from 4-24 nM, but demonstrates no affinity for the other 5-HT subtypes or other neurotransmitter receptors.{31001} In vitro, flibanserin has been shown to reduce forskolin-stimulated cAMP formation in cells and rat tissues and to antagonize the accumulation of phosphatidyl inositol turnover induced by 5-HT in the mouse cortex.{31001} At 10 mg/kg, flibanserin can reduce serotonin in the prefrontal cortex and dorsal raphe of conscious rats while increasing extracellular noradrenaline and dopamine.{31001} Multifunctional serotonergic ligands like flibanserin that can enhance downstream release of dopamine and norepinephrine while concomitantly reducing serotonin release in the brain circuits that mediate symptoms of reduced sexual interest and desire are being studied clinically for therapeutic potential to improve sexual functioning.{31002}
Brand:CaymanSKU:-Available on backorder
FLLL32 is a cell-permeable analog of curcumin (Item No. 81025) that inhibits JAK2-mediated phosphorylation of STAT3 on Tyr705 in cancer cells (IC50 = ~5 µM).{33676,18692} It blocks signaling from IFN-α or IL-6 through JAK2/STAT3 and induces apoptosis in several types of cancer cells.{33676,18692} FLLL32 does not interfere with IFN-γ-induced STAT1 signaling and does not adversely affect the function or viability of immune cells.{33676} Through its effects on JAK2/STAT3 signaling, FLLL32 enhances the chemo- and radiosensitivity of cancer cells.{18692,33675,33677}
Brand:CaymanSKU:10638 - 1 mgAvailable on backorder
FLLL32 is a cell-permeable analog of curcumin (Item No. 81025) that inhibits JAK2-mediated phosphorylation of STAT3 on Tyr705 in cancer cells (IC50 = ~5 µM).{33676,18692} It blocks signaling from IFN-α or IL-6 through JAK2/STAT3 and induces apoptosis in several types of cancer cells.{33676,18692} FLLL32 does not interfere with IFN-γ-induced STAT1 signaling and does not adversely affect the function or viability of immune cells.{33676} Through its effects on JAK2/STAT3 signaling, FLLL32 enhances the chemo- and radiosensitivity of cancer cells.{18692,33675,33677}
Brand:CaymanSKU:10638 - 10 mgAvailable on backorder
FLLL32 is a cell-permeable analog of curcumin (Item No. 81025) that inhibits JAK2-mediated phosphorylation of STAT3 on Tyr705 in cancer cells (IC50 = ~5 µM).{33676,18692} It blocks signaling from IFN-α or IL-6 through JAK2/STAT3 and induces apoptosis in several types of cancer cells.{33676,18692} FLLL32 does not interfere with IFN-γ-induced STAT1 signaling and does not adversely affect the function or viability of immune cells.{33676} Through its effects on JAK2/STAT3 signaling, FLLL32 enhances the chemo- and radiosensitivity of cancer cells.{18692,33675,33677}
Brand:CaymanSKU:10638 - 25 mgAvailable on backorder
FLLL32 is a cell-permeable analog of curcumin (Item No. 81025) that inhibits JAK2-mediated phosphorylation of STAT3 on Tyr705 in cancer cells (IC50 = ~5 µM).{33676,18692} It blocks signaling from IFN-α or IL-6 through JAK2/STAT3 and induces apoptosis in several types of cancer cells.{33676,18692} FLLL32 does not interfere with IFN-γ-induced STAT1 signaling and does not adversely affect the function or viability of immune cells.{33676} Through its effects on JAK2/STAT3 signaling, FLLL32 enhances the chemo- and radiosensitivity of cancer cells.{18692,33675,33677}
Brand:CaymanSKU:10638 - 5 mgAvailable on backorder
Flonicamid is a pyridinecarboxamide insecticide.{37695} It inhibits the brown planthopper (N. lugens) inward-rectifying potassium channel Kir1 (IC50 = 0.64 µM). Flonicamid (100 µg/ml) inhibits aphid (M. persicae) salivation and sap ingestion during feeding on Japanese radish leaves.{37696} It induces toxicity in the aphid species A. gossypii, R. padi, S. graminum, and L. erysimi (LC50s = 0.64, 0.74, 0.78, and 2.01 µg/ml, respectively) and rats (LD50 = ≥844 mg/kg).{37697,37696} Formulations containing flonicamid have been used for the control of pest insects in agriculture.
Brand:CaymanSKU:25608 - 10 mgAvailable on backorder
Flonicamid is a pyridinecarboxamide insecticide.{37695} It inhibits the brown planthopper (N. lugens) inward-rectifying potassium channel Kir1 (IC50 = 0.64 µM). Flonicamid (100 µg/ml) inhibits aphid (M. persicae) salivation and sap ingestion during feeding on Japanese radish leaves.{37696} It induces toxicity in the aphid species A. gossypii, R. padi, S. graminum, and L. erysimi (LC50s = 0.64, 0.74, 0.78, and 2.01 µg/ml, respectively) and rats (LD50 = ≥844 mg/kg).{37697,37696} Formulations containing flonicamid have been used for the control of pest insects in agriculture.
Brand:CaymanSKU:25608 - 25 mgAvailable on backorder
Flonicamid is a pyridinecarboxamide insecticide.{37695} It inhibits the brown planthopper (N. lugens) inward-rectifying potassium channel Kir1 (IC50 = 0.64 µM). Flonicamid (100 µg/ml) inhibits aphid (M. persicae) salivation and sap ingestion during feeding on Japanese radish leaves.{37696} It induces toxicity in the aphid species A. gossypii, R. padi, S. graminum, and L. erysimi (LC50s = 0.64, 0.74, 0.78, and 2.01 µg/ml, respectively) and rats (LD50 = ≥844 mg/kg).{37697,37696} Formulations containing flonicamid have been used for the control of pest insects in agriculture.
Brand:CaymanSKU:25608 - 5 mgAvailable on backorder
Flonicamid is a pyridinecarboxamide insecticide.{37695} It inhibits the brown planthopper (N. lugens) inward-rectifying potassium channel Kir1 (IC50 = 0.64 µM). Flonicamid (100 µg/ml) inhibits aphid (M. persicae) salivation and sap ingestion during feeding on Japanese radish leaves.{37696} It induces toxicity in the aphid species A. gossypii, R. padi, S. graminum, and L. erysimi (LC50s = 0.64, 0.74, 0.78, and 2.01 µg/ml, respectively) and rats (LD50 = ≥844 mg/kg).{37697,37696} Formulations containing flonicamid have been used for the control of pest insects in agriculture.
Brand:CaymanSKU:25608 - 50 mgAvailable on backorder
Florfenicol is a broad-spectrum fluorinated antibiotic and a derivative of thiamphenicol (Item No. 21357).{53126} It is active against human clinical isolates of enteric bacteria, including E. coli, Klebsiella, Enterobacter, Citrobacter, P. mirabilis, and Salmonella (MIC50s = 6.3-12.5 µg/ml).{53127} Florfenicol is also active against clinical isolates of various bovine and porcine respiratory tract pathogens, including P. multocida, A. pleuropneumoniae, and B. bronchiseptica (MIC50s = 0.25-4 µg/ml).{53128} It inhibits peptidyl transferase activity in 70S ribosomes isolated from E. coli when used at a concentration of 1 mM.{53126} Formulations containing florfenicol have been used in the treatment of infectious respiratory disease in cattle.
Brand:CaymanSKU:-Available on backorder
Florfenicol is a broad-spectrum fluorinated antibiotic and a derivative of thiamphenicol (Item No. 21357).{53126} It is active against human clinical isolates of enteric bacteria, including E. coli, Klebsiella, Enterobacter, Citrobacter, P. mirabilis, and Salmonella (MIC50s = 6.3-12.5 µg/ml).{53127} Florfenicol is also active against clinical isolates of various bovine and porcine respiratory tract pathogens, including P. multocida, A. pleuropneumoniae, and B. bronchiseptica (MIC50s = 0.25-4 µg/ml).{53128} It inhibits peptidyl transferase activity in 70S ribosomes isolated from E. coli when used at a concentration of 1 mM.{53126} Formulations containing florfenicol have been used in the treatment of infectious respiratory disease in cattle.
Brand:CaymanSKU:-Available on backorder
Florfenicol is a broad-spectrum fluorinated antibiotic and a derivative of thiamphenicol (Item No. 21357).{53126} It is active against human clinical isolates of enteric bacteria, including E. coli, Klebsiella, Enterobacter, Citrobacter, P. mirabilis, and Salmonella (MIC50s = 6.3-12.5 µg/ml).{53127} Florfenicol is also active against clinical isolates of various bovine and porcine respiratory tract pathogens, including P. multocida, A. pleuropneumoniae, and B. bronchiseptica (MIC50s = 0.25-4 µg/ml).{53128} It inhibits peptidyl transferase activity in 70S ribosomes isolated from E. coli when used at a concentration of 1 mM.{53126} Formulations containing florfenicol have been used in the treatment of infectious respiratory disease in cattle.
Brand:CaymanSKU:-Available on backorder
Florfenicol is a broad-spectrum fluorinated antibiotic and a derivative of thiamphenicol (Item No. 21357).{53126} It is active against human clinical isolates of enteric bacteria, including E. coli, Klebsiella, Enterobacter, Citrobacter, P. mirabilis, and Salmonella (MIC50s = 6.3-12.5 µg/ml).{53127} Florfenicol is also active against clinical isolates of various bovine and porcine respiratory tract pathogens, including P. multocida, A. pleuropneumoniae, and B. bronchiseptica (MIC50s = 0.25-4 µg/ml).{53128} It inhibits peptidyl transferase activity in 70S ribosomes isolated from E. coli when used at a concentration of 1 mM.{53126} Formulations containing florfenicol have been used in the treatment of infectious respiratory disease in cattle.
Brand:CaymanSKU:-Available on backorder
Florfenicol amine is a major metabolite of the antibiotic florfenicol, a fluorinated derivative of chloramphenicol that is commonly used in veterinary medicine.{30176,30177} The pharmacokinetics of florfenicol and florfenicol amine are commonly studied in edible tissues from domestic animals.{30174,30175,30178}
Brand:CaymanSKU:-Available on backorder
Florfenicol amine is a major metabolite of the antibiotic florfenicol, a fluorinated derivative of chloramphenicol that is commonly used in veterinary medicine.{30176,30177} The pharmacokinetics of florfenicol and florfenicol amine are commonly studied in edible tissues from domestic animals.{30174,30175,30178}
Brand:CaymanSKU:-Available on backorder
Florfenicol amine is a major metabolite of the antibiotic florfenicol, a fluorinated derivative of chloramphenicol that is commonly used in veterinary medicine.{30176,30177} The pharmacokinetics of florfenicol and florfenicol amine are commonly studied in edible tissues from domestic animals.{30174,30175,30178}
Brand:CaymanSKU:-Available on backorder
Florfenicol-d3 is intended for use as an internal standard for the quantification of florfenicol (Item No. 19458) by GC- or LC-MS. Florfenicol is a broad-spectrum fluorinated antibiotic and a derivative of thiamphenicol (Item No. 21357).{53126} It is active against human clinical isolates of enteric bacteria, including E. coli, Klebsiella, Enterobacter, Citrobacter, P. mirabilis, and Salmonella (MIC50s = 6.3-12.5 µg/ml).{53127} Florfenicol is also active against clinical isolates of various bovine and porcine respiratory tract pathogens, including P. multocida, A. pleuropneumoniae, and B. bronchiseptica (MIC50s = 0.25-4 µg/ml).{53128} It inhibits peptidyl transferase activity in 70S ribosomes isolated from E. coli when used at a concentration of 1 mM.{53126} Formulations containing florfenicol have been used in the treatment of infectious respiratory disease in cattle.
Brand:CaymanSKU:28538 - 1 mgAvailable on backorder
Floxuridine is a prodrug that is rapidly catabolized in vivo to 5-fluorouracil when administered by rapid injection.{22465} In addition, floxuridine inhibits thymidylate synthase (EC50 = 0.6 nM), interfering with DNA synthesis.{22463,22473} It has been used to treat various cancers, particularly metastases to the liver.{22466}
Brand:CaymanSKU:- Floxuridine is a prodrug that is rapidly catabolized in vivo to 5-fluorouracil when administered by rapid injection.{22465} In addition, floxuridine inhibits thymidylate synthase (EC50 = 0.6 nM), interfering with DNA synthesis.{22463,22473} It has been used to treat various cancers, particularly metastases to the liver.{22466}
Brand:CaymanSKU:- Floxuridine is a prodrug that is rapidly catabolized in vivo to 5-fluorouracil when administered by rapid injection.{22465} In addition, floxuridine inhibits thymidylate synthase (EC50 = 0.6 nM), interfering with DNA synthesis.{22463,22473} It has been used to treat various cancers, particularly metastases to the liver.{22466}
Brand:CaymanSKU:-
Fms-like tyrosine kinase (FLT3) is a cell-surface receptor with important roles in stem cell development, hematopoiesis, and cancer.{29996,29997} FLT3 Inhibitor is a cell-permeable, ATP-competitive inhibitor of FLT3 (IC50 = 27 nM) that blocks the proliferation of myelomonocytic leukemia MV4-11 cells (IC50 = 0.41 µM).{29998} It is selective for FLT3 over a panel of 22 other kinases. FLT3 Inhibitor synergistically increases the cytotoxicity of an AF4-mimetic peptide against MV4-11 cells.{29995}
Brand:CaymanSKU:-Available on backorder
Fms-like tyrosine kinase (FLT3) is a cell-surface receptor with important roles in stem cell development, hematopoiesis, and cancer.{29996,29997} FLT3 Inhibitor is a cell-permeable, ATP-competitive inhibitor of FLT3 (IC50 = 27 nM) that blocks the proliferation of myelomonocytic leukemia MV4-11 cells (IC50 = 0.41 µM).{29998} It is selective for FLT3 over a panel of 22 other kinases. FLT3 Inhibitor synergistically increases the cytotoxicity of an AF4-mimetic peptide against MV4-11 cells.{29995}
Brand:CaymanSKU:-Available on backorder
Fms-like tyrosine kinase (FLT3) is a cell-surface receptor with important roles in stem cell development, hematopoiesis, and cancer.{29996,29997} FLT3 Inhibitor is a cell-permeable, ATP-competitive inhibitor of FLT3 (IC50 = 27 nM) that blocks the proliferation of myelomonocytic leukemia MV4-11 cells (IC50 = 0.41 µM).{29998} It is selective for FLT3 over a panel of 22 other kinases. FLT3 Inhibitor synergistically increases the cytotoxicity of an AF4-mimetic peptide against MV4-11 cells.{29995}
Brand:CaymanSKU:-Available on backorder
Fms-like tyrosine kinase (FLT3) is a cell-surface receptor with important roles in stem cell development, hematopoiesis, and cancer.{29996,29997} FLT3 Inhibitor is a cell-permeable, ATP-competitive inhibitor of FLT3 (IC50 = 27 nM) that blocks the proliferation of myelomonocytic leukemia MV4-11 cells (IC50 = 0.41 µM).{29998} It is selective for FLT3 over a panel of 22 other kinases. FLT3 Inhibitor synergistically increases the cytotoxicity of an AF4-mimetic peptide against MV4-11 cells.{29995}
Brand:CaymanSKU:-Available on backorder
FLT3 Inhibitor III is a potent inhibitor of Fms-like tyrosine kinase 3 (FLT3; IC50 = 50 nM).{33905} It shows high selectivity for FLT3 over a panel of 300 other kinases.{33905,28555} FLT3 Inhibitor III blocks FLT-dependent cell proliferation in a dose-dependent manner.{33905} FLT3 Inhibitor III has been used to study signaling through FLT3 and FLT3 with internal tandem duplications (FLT3-ITD) in cells.{33904,33906,33907}
Brand:CaymanSKU:21193 -Out of stock
FLT3 Inhibitor III is a potent inhibitor of Fms-like tyrosine kinase 3 (FLT3; IC50 = 50 nM).{33905} It shows high selectivity for FLT3 over a panel of 300 other kinases.{33905,28555} FLT3 Inhibitor III blocks FLT-dependent cell proliferation in a dose-dependent manner.{33905} FLT3 Inhibitor III has been used to study signaling through FLT3 and FLT3 with internal tandem duplications (FLT3-ITD) in cells.{33904,33906,33907}
Brand:CaymanSKU:21193 -Out of stock
FLT3-IN-2 is an inhibitor of FMS-related tyrosine kinase 3 (FLT3), c-Kit, and c-FMS (IC50s = <1 μM for all).{54061,54062}
Brand:CaymanSKU:30070 - 1 mgAvailable on backorder
FLT3-IN-2 is an inhibitor of FMS-related tyrosine kinase 3 (FLT3), c-Kit, and c-FMS (IC50s = <1 μM for all).{54061,54062}
Brand:CaymanSKU:30070 - 10 mgAvailable on backorder
FLT3-IN-2 is an inhibitor of FMS-related tyrosine kinase 3 (FLT3), c-Kit, and c-FMS (IC50s = <1 μM for all).{54061,54062}
Brand:CaymanSKU:30070 - 25 mgAvailable on backorder
FLT3-IN-2 is an inhibitor of FMS-related tyrosine kinase 3 (FLT3), c-Kit, and c-FMS (IC50s = <1 μM for all).{54061,54062}
Brand:CaymanSKU:30070 - 5 mgAvailable on backorder
Fluazuron is an acaricide widely-used to control tick populations in cattle, sheep, and pigs.{40004, 40005} Fluazuron inhibits chitin formation limiting viable egg production and prevents immature ticks from moulting.{40004} It is effective against populations of R. microplus, R. sanguineus, S. scabei, and Y. pestis at host doses ranging from 1.5 to 100 mg/kg.{40004,40006,40007,40008,40009} Fluazuron does not effect populations of F. candida or O. gazella, alleviating concerns about non-specific insecticide activity.{40005,40010} Resistance to fluazuron in certain R. microplus strains may be emerging.{40011}
Brand:CaymanSKU:22283 -Out of stock
Fluazuron is an acaricide widely-used to control tick populations in cattle, sheep, and pigs.{40004, 40005} Fluazuron inhibits chitin formation limiting viable egg production and prevents immature ticks from moulting.{40004} It is effective against populations of R. microplus, R. sanguineus, S. scabei, and Y. pestis at host doses ranging from 1.5 to 100 mg/kg.{40004,40006,40007,40008,40009} Fluazuron does not effect populations of F. candida or O. gazella, alleviating concerns about non-specific insecticide activity.{40005,40010} Resistance to fluazuron in certain R. microplus strains may be emerging.{40011}
Brand:CaymanSKU:22283 -Out of stock
Fluazuron is an acaricide widely-used to control tick populations in cattle, sheep, and pigs.{40004, 40005} Fluazuron inhibits chitin formation limiting viable egg production and prevents immature ticks from moulting.{40004} It is effective against populations of R. microplus, R. sanguineus, S. scabei, and Y. pestis at host doses ranging from 1.5 to 100 mg/kg.{40004,40006,40007,40008,40009} Fluazuron does not effect populations of F. candida or O. gazella, alleviating concerns about non-specific insecticide activity.{40005,40010} Resistance to fluazuron in certain R. microplus strains may be emerging.{40011}
Brand:CaymanSKU:22283 -Out of stock
Flubendazole is a benzimidazole carbamate anthelmintic.{42565} It completely eliminates larvae in a mouse model of A. cantonensis infection and exhibits a mean larval reduction of 100% in a T. spiralis infection model when administered at doses of 5 and 50 mg/kg per day, respectively.{42566} Flubendazole inhibits mammalian tubulin polymerization (IC50 = 2.5 µM) and inhibits binding of [3H]mebendazole to H. contortus L3 larval tubulin (IC50 = 0.17 µM).{41688} Flubendazole also inhibits the proliferation of BT-549, SK-BR-3, MDA-MB-231, and MCF-7 breast cancer cells (IC50s = 0.72, 1.51, 1.75, and 5.51 µM, respectively) and reduces tumor growth in an MDA-MB-231 mouse xenograft model when administered at a dose of 25 mg/kg.{42568}
Brand:CaymanSKU:26064 - 10 gAvailable on backorder
Flubendazole is a benzimidazole carbamate anthelmintic.{42565} It completely eliminates larvae in a mouse model of A. cantonensis infection and exhibits a mean larval reduction of 100% in a T. spiralis infection model when administered at doses of 5 and 50 mg/kg per day, respectively.{42566} Flubendazole inhibits mammalian tubulin polymerization (IC50 = 2.5 µM) and inhibits binding of [3H]mebendazole to H. contortus L3 larval tubulin (IC50 = 0.17 µM).{41688} Flubendazole also inhibits the proliferation of BT-549, SK-BR-3, MDA-MB-231, and MCF-7 breast cancer cells (IC50s = 0.72, 1.51, 1.75, and 5.51 µM, respectively) and reduces tumor growth in an MDA-MB-231 mouse xenograft model when administered at a dose of 25 mg/kg.{42568}
Brand:CaymanSKU:26064 - 25 gAvailable on backorder
Flubendazole is a benzimidazole carbamate anthelmintic.{42565} It completely eliminates larvae in a mouse model of A. cantonensis infection and exhibits a mean larval reduction of 100% in a T. spiralis infection model when administered at doses of 5 and 50 mg/kg per day, respectively.{42566} Flubendazole inhibits mammalian tubulin polymerization (IC50 = 2.5 µM) and inhibits binding of [3H]mebendazole to H. contortus L3 larval tubulin (IC50 = 0.17 µM).{41688} Flubendazole also inhibits the proliferation of BT-549, SK-BR-3, MDA-MB-231, and MCF-7 breast cancer cells (IC50s = 0.72, 1.51, 1.75, and 5.51 µM, respectively) and reduces tumor growth in an MDA-MB-231 mouse xenograft model when administered at a dose of 25 mg/kg.{42568}
Brand:CaymanSKU:26064 - 5 gAvailable on backorder
Flubendazole is a benzimidazole carbamate anthelmintic.{42565} It completely eliminates larvae in a mouse model of A. cantonensis infection and exhibits a mean larval reduction of 100% in a T. spiralis infection model when administered at doses of 5 and 50 mg/kg per day, respectively.{42566} Flubendazole inhibits mammalian tubulin polymerization (IC50 = 2.5 µM) and inhibits binding of [3H]mebendazole to H. contortus L3 larval tubulin (IC50 = 0.17 µM).{41688} Flubendazole also inhibits the proliferation of BT-549, SK-BR-3, MDA-MB-231, and MCF-7 breast cancer cells (IC50s = 0.72, 1.51, 1.75, and 5.51 µM, respectively) and reduces tumor growth in an MDA-MB-231 mouse xenograft model when administered at a dose of 25 mg/kg.{42568}
Brand:CaymanSKU:26064 - 50 gAvailable on backorder
Flubromazepam (Item No. 15157) is an analytical reference standard categorized as a benzodiazepine.{24725} Flubromazepam has been detected in seized samples and has anxiolytic and sedative properties.{30787,53837} This product is intended for research and forensic applications.
Brand:CaymanSKU:- Flubromazepam (Item No. 15157) is an analytical reference standard categorized as a benzodiazepine.{24725} Flubromazepam has been detected in seized samples and has anxiolytic and sedative properties.{30787,53837} This product is intended for research and forensic applications.
Brand:CaymanSKU:- Flubromazepam (Item No. 15157) is an analytical reference standard categorized as a benzodiazepine.{24725} Flubromazepam has been detected in seized samples and has anxiolytic and sedative properties.{30787,53837} This product is intended for research and forensic applications.
Brand:CaymanSKU:-
Fluclotizolam (Item No. 23524) is an analytical reference standard categorized as a thienotriazolodiazepine.{49118} This product is intended for research and forensic applications.
Brand:CaymanSKU:23524 - 1 mgAvailable on backorder
Fluconazole is a triazole antifungal agent that is effective against most Candida strains.{20805} In vivo fluconazole at 0.5-100 mg/kg demonstrates protective activity in various experimental animal models of systemic fungal diseases including aspergillosis, blastomycosis, candidiasis, coccidioidomycosis, cryptococcosis, and histoplasmosis.{23407}
Brand:CaymanSKU:11594 - 1 gAvailable on backorder
Fluconazole is a triazole antifungal agent that is effective against most Candida strains.{20805} In vivo fluconazole at 0.5-100 mg/kg demonstrates protective activity in various experimental animal models of systemic fungal diseases including aspergillosis, blastomycosis, candidiasis, coccidioidomycosis, cryptococcosis, and histoplasmosis.{23407}
Brand:CaymanSKU:11594 - 10 gAvailable on backorder
Fluconazole is a triazole antifungal agent that is effective against most Candida strains.{20805} In vivo fluconazole at 0.5-100 mg/kg demonstrates protective activity in various experimental animal models of systemic fungal diseases including aspergillosis, blastomycosis, candidiasis, coccidioidomycosis, cryptococcosis, and histoplasmosis.{23407}
Brand:CaymanSKU:11594 - 5 gAvailable on backorder
Fluconazole is a triazole antifungal agent that is effective against most Candida strains.{20805} In vivo fluconazole at 0.5-100 mg/kg demonstrates protective activity in various experimental animal models of systemic fungal diseases including aspergillosis, blastomycosis, candidiasis, coccidioidomycosis, cryptococcosis, and histoplasmosis.{23407}
Brand:CaymanSKU:11594 - 500 mgAvailable on backorder
Fluconazole-d4 is intended for use as an internal standard for the quantification of fluconazole (Item No. 11594) by GC- or LC-MS. Fluconazole is a triazole antifungal agent that is effective against most Candida strains.{20805} In vivo, fluconazole at 0.5-100 mg/kg demonstrates protective activity in various experimental animal models of systemic fungal diseases including aspergillosis, blastomycosis, candidiasis, coccidioidomycosis, cryptococcosis, and histoplasmosis.{23407}
Brand:CaymanSKU:-Available on backorder
Fluconazole-d4 is intended for use as an internal standard for the quantification of fluconazole (Item No. 11594) by GC- or LC-MS. Fluconazole is a triazole antifungal agent that is effective against most Candida strains.{20805} In vivo, fluconazole at 0.5-100 mg/kg demonstrates protective activity in various experimental animal models of systemic fungal diseases including aspergillosis, blastomycosis, candidiasis, coccidioidomycosis, cryptococcosis, and histoplasmosis.{23407}
Brand:CaymanSKU:-Available on backorder
Fluconazole-d4 is intended for use as an internal standard for the quantification of fluconazole (Item No. 11594) by GC- or LC-MS. Fluconazole is a triazole antifungal agent that is effective against most Candida strains.{20805} In vivo, fluconazole at 0.5-100 mg/kg demonstrates protective activity in various experimental animal models of systemic fungal diseases including aspergillosis, blastomycosis, candidiasis, coccidioidomycosis, cryptococcosis, and histoplasmosis.{23407}
Brand:CaymanSKU:-Available on backorder
Because of their antitumor activity via inhibition of DNA synthesis, purine nucleoside derivatives resistant to deamination have been developed for the treatment of various leukemias.{22555,21535} Fludarabine is an adenosine deaminase resistant analog of 9-β-D-arabinofuranosyladenine (ara-A) that disrupts ribonucleotide reductase and DNA polymerase in blood cells. It exhibits antiproliferative activity (IC50 = 1.54 μM in an RPMI-8226 myeloma cell line) and triggers apoptosis through increasing Bax and decreasing Bid, XIAP, and survivin expression.{22556,22553} Fludarabine is effective in a number of animal tumor systems including LI210 leukemia, CD8F mammary adenocarcinoma, P388 leukemia, and human LX-1 lung tumor xenograft and displays anticancer activity against human hematological malignancies in vivo.{22565,22552,22557}
Brand:CaymanSKU:- Because of their antitumor activity via inhibition of DNA synthesis, purine nucleoside derivatives resistant to deamination have been developed for the treatment of various leukemias.{22555,21535} Fludarabine is an adenosine deaminase resistant analog of 9-β-D-arabinofuranosyladenine (ara-A) that disrupts ribonucleotide reductase and DNA polymerase in blood cells. It exhibits antiproliferative activity (IC50 = 1.54 μM in an RPMI-8226 myeloma cell line) and triggers apoptosis through increasing Bax and decreasing Bid, XIAP, and survivin expression.{22556,22553} Fludarabine is effective in a number of animal tumor systems including LI210 leukemia, CD8F mammary adenocarcinoma, P388 leukemia, and human LX-1 lung tumor xenograft and displays anticancer activity against human hematological malignancies in vivo.{22565,22552,22557}
Brand:CaymanSKU:- Because of their antitumor activity via inhibition of DNA synthesis, purine nucleoside derivatives resistant to deamination have been developed for the treatment of various leukemias.{22555,21535} Fludarabine is an adenosine deaminase resistant analog of 9-β-D-arabinofuranosyladenine (ara-A) that disrupts ribonucleotide reductase and DNA polymerase in blood cells. It exhibits antiproliferative activity (IC50 = 1.54 μM in an RPMI-8226 myeloma cell line) and triggers apoptosis through increasing Bax and decreasing Bid, XIAP, and survivin expression.{22556,22553} Fludarabine is effective in a number of animal tumor systems including LI210 leukemia, CD8F mammary adenocarcinoma, P388 leukemia, and human LX-1 lung tumor xenograft and displays anticancer activity against human hematological malignancies in vivo.{22565,22552,22557}
Brand:CaymanSKU:- Because of their antitumor activity via inhibition of DNA synthesis, purine nucleoside derivatives resistant to deamination have been developed for the treatment of various leukemias.{22555,21535} Fludarabine is an adenosine deaminase resistant analog of 9-β-D-arabinofuranosyladenine (ara-A) that disrupts ribonucleotide reductase and DNA polymerase in blood cells. It exhibits antiproliferative activity (IC50 = 1.54 μM in an RPMI-8226 myeloma cell line) and triggers apoptosis through increasing Bax and decreasing Bid, XIAP, and survivin expression.{22556,22553} Fludarabine is effective in a number of animal tumor systems including LI210 leukemia, CD8F mammary adenocarcinoma, P388 leukemia, and human LX-1 lung tumor xenograft and displays anticancer activity against human hematological malignancies in vivo.{22565,22552,22557}
Brand:CaymanSKU:-
Fludarabine phosphate is an injectable form of fludarabine (Item No. 14128).{22565} Fludarabine is an adenosine deaminase resistant analog of 9-β-D-arabinofuranosyladenine (ara-A) that disrupts ribonucleotide reductase and DNA polymerase in blood cells. It exhibits antiproliferative activity (IC50 = 1.54 μM in an RPMI-8226 myeloma cell line) and triggers apoptosis by increasing Bax and decreasing Bid, XIAP, and survivin expression.{22556,22553} Fludarabine is effective in a number of animal tumor systems including LI210 leukemia, CD8F mammary adenocarcinoma, P388 leukemia, and human LX-1 lung tumor xenograft and displays anti-cancer activity against human hematological malignancies in vivo.{22565,22552,22557}
Brand:CaymanSKU:- Fludarabine phosphate is an injectable form of fludarabine (Item No. 14128).{22565} Fludarabine is an adenosine deaminase resistant analog of 9-β-D-arabinofuranosyladenine (ara-A) that disrupts ribonucleotide reductase and DNA polymerase in blood cells. It exhibits antiproliferative activity (IC50 = 1.54 μM in an RPMI-8226 myeloma cell line) and triggers apoptosis by increasing Bax and decreasing Bid, XIAP, and survivin expression.{22556,22553} Fludarabine is effective in a number of animal tumor systems including LI210 leukemia, CD8F mammary adenocarcinoma, P388 leukemia, and human LX-1 lung tumor xenograft and displays anti-cancer activity against human hematological malignancies in vivo.{22565,22552,22557}
Brand:CaymanSKU:- Fludarabine phosphate is an injectable form of fludarabine (Item No. 14128).{22565} Fludarabine is an adenosine deaminase resistant analog of 9-β-D-arabinofuranosyladenine (ara-A) that disrupts ribonucleotide reductase and DNA polymerase in blood cells. It exhibits antiproliferative activity (IC50 = 1.54 μM in an RPMI-8226 myeloma cell line) and triggers apoptosis by increasing Bax and decreasing Bid, XIAP, and survivin expression.{22556,22553} Fludarabine is effective in a number of animal tumor systems including LI210 leukemia, CD8F mammary adenocarcinoma, P388 leukemia, and human LX-1 lung tumor xenograft and displays anti-cancer activity against human hematological malignancies in vivo.{22565,22552,22557}
Brand:CaymanSKU:- Fludarabine phosphate is an injectable form of fludarabine (Item No. 14128).{22565} Fludarabine is an adenosine deaminase resistant analog of 9-β-D-arabinofuranosyladenine (ara-A) that disrupts ribonucleotide reductase and DNA polymerase in blood cells. It exhibits antiproliferative activity (IC50 = 1.54 μM in an RPMI-8226 myeloma cell line) and triggers apoptosis by increasing Bax and decreasing Bid, XIAP, and survivin expression.{22556,22553} Fludarabine is effective in a number of animal tumor systems including LI210 leukemia, CD8F mammary adenocarcinoma, P388 leukemia, and human LX-1 lung tumor xenograft and displays anti-cancer activity against human hematological malignancies in vivo.{22565,22552,22557}
Brand:CaymanSKU:- Fludarabine phosphate is an injectable form of fludarabine (Item No. 14128).{22565} Fludarabine is an adenosine deaminase resistant analog of 9-β-D-arabinofuranosyladenine (ara-A) that disrupts ribonucleotide reductase and DNA polymerase in blood cells. It exhibits antiproliferative activity (IC50 = 1.54 μM in an RPMI-8226 myeloma cell line) and triggers apoptosis by increasing Bax and decreasing Bid, XIAP, and survivin expression.{22556,22553} Fludarabine is effective in a number of animal tumor systems including LI210 leukemia, CD8F mammary adenocarcinoma, P388 leukemia, and human LX-1 lung tumor xenograft and displays anti-cancer activity against human hematological malignancies in vivo.{22565,22552,22557}
Brand:CaymanSKU:-
Fludioxonil is a phenylpyrrole fungicide.{42436} It inhibits the growth of B. cinerea isolates from strawberry and blackberry crops (EC50s = 0.06-0.38 mg/L).{42437} Fludioxonil also inhibits the growth of S. cerevisiae AF293 and C. albicans IFO1385 in a concentration-dependent manner.{42436,42438} It is an estrogen receptor α (ERα) agonist (EC50 = 3.7 μM in a yeast reporter assay) that induces expression of the oncogenic microRNA miR-21, inhibits estradiol-induced proliferation, and reduces cell motility of MCF-7 breast cancer cells in vitro.{42439}
Brand:CaymanSKU:25818 - 100 mgAvailable on backorder
Fludioxonil is a phenylpyrrole fungicide.{42436} It inhibits the growth of B. cinerea isolates from strawberry and blackberry crops (EC50s = 0.06-0.38 mg/L).{42437} Fludioxonil also inhibits the growth of S. cerevisiae AF293 and C. albicans IFO1385 in a concentration-dependent manner.{42436,42438} It is an estrogen receptor α (ERα) agonist (EC50 = 3.7 μM in a yeast reporter assay) that induces expression of the oncogenic microRNA miR-21, inhibits estradiol-induced proliferation, and reduces cell motility of MCF-7 breast cancer cells in vitro.{42439}
Brand:CaymanSKU:25818 - 50 mgAvailable on backorder
Fludrocortisone is a synthetic mineralocorticoid.{52236} Dietary administration of fludrocortisone (10 μg/kg per day) reduces tympanic membrane thickness and fluid area in a mouse model of S. pneumoniae-induced middle ear inflammation. Formulations containing fludrocortisone have been used in the treatment of Addison’s disease.
Brand:CaymanSKU:29391 - 1 mgAvailable on backorder
Fludrocortisone is a synthetic mineralocorticoid.{52236} Dietary administration of fludrocortisone (10 μg/kg per day) reduces tympanic membrane thickness and fluid area in a mouse model of S. pneumoniae-induced middle ear inflammation. Formulations containing fludrocortisone have been used in the treatment of Addison’s disease.
Brand:CaymanSKU:29391 - 5 mgAvailable on backorder
Fludrocortisone is a synthetic mineralocorticoid.{52236} Dietary administration of fludrocortisone (10 μg/kg per day) reduces tympanic membrane thickness and fluid area in a mouse model of S. pneumoniae-induced middle ear inflammation. Formulations containing fludrocortisone have been used in the treatment of Addison’s disease.
Brand:CaymanSKU:29391 - 500 µgAvailable on backorder
Fludrocortisone acetate is the acetate form of the synthetic corticosteroid fludrocortisone, which is a mineralocorticoid receptor agonist.{39390} Fludrocortisone acetate (0.1-5 µg/animal) promotes sodium retention in rats in a dose-dependent manner with 37% of sodium excreted compared with control when used at a dose of 5 µg/animal.{39391} Formulations containing fludrocortisone acetate have been used in the treatment of Addison’s disease.
Brand:CaymanSKU:24032 - 1 gAvailable on backorder
Fludrocortisone acetate is the acetate form of the synthetic corticosteroid fludrocortisone, which is a mineralocorticoid receptor agonist.{39390} Fludrocortisone acetate (0.1-5 µg/animal) promotes sodium retention in rats in a dose-dependent manner with 37% of sodium excreted compared with control when used at a dose of 5 µg/animal.{39391} Formulations containing fludrocortisone acetate have been used in the treatment of Addison’s disease.
Brand:CaymanSKU:24032 - 250 mgAvailable on backorder
Fludrocortisone acetate is the acetate form of the synthetic corticosteroid fludrocortisone, which is a mineralocorticoid receptor agonist.{39390} Fludrocortisone acetate (0.1-5 µg/animal) promotes sodium retention in rats in a dose-dependent manner with 37% of sodium excreted compared with control when used at a dose of 5 µg/animal.{39391} Formulations containing fludrocortisone acetate have been used in the treatment of Addison’s disease.
Brand:CaymanSKU:24032 - 500 mgAvailable on backorder