Chemicals

Showing 1501–1650 of 41137 results

  • 1-(3-Methoxyphenyl)piperazine (Item No. 19273) is an analytical reference standard categorized as a piperazine. This product is intended for research and forensic applications.  

     

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    Cayman
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  • 1-(3-Methoxyphenyl)piperazine (Item No. 19273) is an analytical reference standard categorized as a piperazine. This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
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  • 1-(3-Methoxyphenyl)piperazine (Item No. 19273) is an analytical reference standard categorized as a piperazine. This product is intended for research and forensic applications.  

     

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    Cayman
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  • 1-(3-Methylbenzyl)piperazine (Item No. 24018) is an analytical reference standard categorized as a piperazine. It has been detected in illicit tablets.{41394} This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:24018 - 1 mg

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  • 1-(3-Methylbenzyl)piperazine (Item No. 24018) is an analytical reference standard categorized as a piperazine. It has been detected in illicit tablets.{41394} This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:24018 - 5 mg

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  • 1-(3-Methylbenzyl)piperazine (Item No. 24018) is an analytical reference standard categorized as a piperazine. It has been detected in illicit tablets.{41394} This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:24018 - 50 mg

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  • 1-(3-Trifluoromethylphenyl)piperazine (TFMPP) is an entactogenic drug which selectively promotes the release of serotonin.{20498} When used in combination with 1-benzylpiperazine, TFMPP increases both serotonin and dopamine, mirroring the effects of 3,4-methylenedioxymethamphetamine.{20498} Drug-drug synergism may induce seizures.{20498} TFMPP has been identified in party pills and powders.{20500,20497} Its metabolism in rats has been described.{19874} This product is intended for forensic applications.  

     

    Brand:
    Cayman
    SKU:11205 - 10 mg

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  • 1-(3-Trifluoromethylphenyl)piperazine (TFMPP) is an entactogenic drug which selectively promotes the release of serotonin.{20498} When used in combination with 1-benzylpiperazine, TFMPP increases both serotonin and dopamine, mirroring the effects of 3,4-methylenedioxymethamphetamine.{20498} Drug-drug synergism may induce seizures.{20498} TFMPP has been identified in party pills and powders.{20500,20497} Its metabolism in rats has been described.{19874} This product is intended for forensic applications.  

     

    Brand:
    Cayman
    SKU:11205 - 100 mg

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  • 1-(3-Trifluoromethylphenyl)piperazine (TFMPP) is an entactogenic drug which selectively promotes the release of serotonin.{20498} When used in combination with 1-benzylpiperazine, TFMPP increases both serotonin and dopamine, mirroring the effects of 3,4-methylenedioxymethamphetamine.{20498} Drug-drug synergism may induce seizures.{20498} TFMPP has been identified in party pills and powders.{20500,20497} Its metabolism in rats has been described.{19874} This product is intended for forensic applications.  

     

    Brand:
    Cayman
    SKU:11205 - 50 mg

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  • 1-(3,5-Dimethylphenyl)piperazine is a piperidine compound that is inactive at dopamine and serotonin receptors.{32836} It may be used as a heterocyclic building block to develop bioactive compounds.  

     

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    Cayman
    SKU:20627 -

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  • 1-(3,5-Dimethylphenyl)piperazine is a piperidine compound that is inactive at dopamine and serotonin receptors.{32836} It may be used as a heterocyclic building block to develop bioactive compounds.  

     

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    Cayman
    SKU:20627 -

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  • 1-(3,5-Dimethylphenyl)piperazine is a piperidine compound that is inactive at dopamine and serotonin receptors.{32836} It may be used as a heterocyclic building block to develop bioactive compounds.  

     

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    Cayman
    SKU:20627 -

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  • 1-(4-Bromophenyl)piperazine (hydrochloride) (Item No. 30229) is an analytical reference standard categorized as a piperazine. This product is intended for research and forensic applications.  

     

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    Cayman
    SKU:30229 - 1 mg

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  • 1-(4-Bromophenyl)piperazine (hydrochloride) (Item No. 30229) is an analytical reference standard categorized as a piperazine. This product is intended for research and forensic applications.  

     

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    Cayman
    SKU:30229 - 5 mg

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  • 1-(4-Chlorophenyl)piperazine (Item No. 14481) is an analytical reference standard categorized as a piperazine. It is psychoactive and an isomer of 1-(3-chlorophenyl)piperazine (Item No. 13949).{40610} This product is intended for research and forensic applications.  

     

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    Cayman
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  • 1-(4-Chlorophenyl)piperazine (Item No. 14481) is an analytical reference standard categorized as a piperazine. It is psychoactive and an isomer of 1-(3-chlorophenyl)piperazine (Item No. 13949).{40610} This product is intended for research and forensic applications.  

     

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    Cayman
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  • 1-(4-Chlorophenyl)piperazine (Item No. 14481) is an analytical reference standard categorized as a piperazine. It is psychoactive and an isomer of 1-(3-chlorophenyl)piperazine (Item No. 13949).{40610} This product is intended for research and forensic applications.  

     

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    Cayman
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  • 1-(4-Fluorophenyl)-2-methyl-2-propylamine is a fluorinated building block used for the synthesis of various pharmaceutical amides.  

     

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    Cayman
    SKU:9002780 - 100 mg

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  • 1-(4-Fluorophenyl)-2-methyl-2-propylamine is a fluorinated building block used for the synthesis of various pharmaceutical amides.  

     

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    Cayman
    SKU:9002780 - 250 mg

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  • 1-(4-Fluorophenyl)-2-methyl-2-propylamine is a fluorinated building block used for the synthesis of various pharmaceutical amides.  

     

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    Cayman
    SKU:9002780 - 50 mg

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  • Phenylpiperazines are entactogenic drugs which direct central serotonin release.{20499,20498,20500} Substituted phenylpiperazines, such as 1-(3-chlorophenyl)piperazine, have been identified as designer drugs or drugs of abuse.{19758,20497} 1-(4Fluorophenyl)piperazine (hydrochloride) is a substituted phenylpiperazine with a potential for abuse. The physiological and toxicological properties of this compound have not been evaluated. This product is intended for forensic and research applications.  

     

    Brand:
    Cayman
    SKU:11204 - 10 mg

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  • Phenylpiperazines are entactogenic drugs which direct central serotonin release.{20499,20498,20500} Substituted phenylpiperazines, such as 1-(3-chlorophenyl)piperazine, have been identified as designer drugs or drugs of abuse.{19758,20497} 1-(4Fluorophenyl)piperazine (hydrochloride) is a substituted phenylpiperazine with a potential for abuse. The physiological and toxicological properties of this compound have not been evaluated. This product is intended for forensic and research applications.  

     

    Brand:
    Cayman
    SKU:11204 - 100 mg

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  • Phenylpiperazines are entactogenic drugs which direct central serotonin release.{20499,20498,20500} Substituted phenylpiperazines, such as 1-(3-chlorophenyl)piperazine, have been identified as designer drugs or drugs of abuse.{19758,20497} 1-(4Fluorophenyl)piperazine (hydrochloride) is a substituted phenylpiperazine with a potential for abuse. The physiological and toxicological properties of this compound have not been evaluated. This product is intended for forensic and research applications.  

     

    Brand:
    Cayman
    SKU:11204 - 50 mg

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  • 1-(4-Methoxyphenyl)piperazine (hydrochloride) is a piperazine derivative with euphoric, stimulant properties comparable to those produced by amphetamine.{19874,21281} It is assumed to have a mixed mechanism of action, with serotonergic and dopamine antagonistic properties in a similar fashion to 3,4-methylenedioxymethamphetamine. Also, its metabolism has been described.{19874,20497} This product is intended for research and forensic purposes.  

     

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    Cayman
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  • 1-(4-Methoxyphenyl)piperazine (hydrochloride) is a piperazine derivative with euphoric, stimulant properties comparable to those produced by amphetamine.{19874,21281} It is assumed to have a mixed mechanism of action, with serotonergic and dopamine antagonistic properties in a similar fashion to 3,4-methylenedioxymethamphetamine. Also, its metabolism has been described.{19874,20497} This product is intended for research and forensic purposes.  

     

    Brand:
    Cayman
    SKU:-
  • 1-(4-Methoxyphenyl)piperazine (hydrochloride) is a piperazine derivative with euphoric, stimulant properties comparable to those produced by amphetamine.{19874,21281} It is assumed to have a mixed mechanism of action, with serotonergic and dopamine antagonistic properties in a similar fashion to 3,4-methylenedioxymethamphetamine. Also, its metabolism has been described.{19874,20497} This product is intended for research and forensic purposes.  

     

    Brand:
    Cayman
    SKU:-
  • 1-(6-Methoxy-2-naphthyl)ethanol is a potential impurity in commercial preparations of naproxen.{38232} Naproxen (Item No. 70290) is a non-selective COX inhibitor.{1286,1791} The IC50 values for human recombinant COX-1 and -2 are 0.6-4.8 µM and 2.0-28.4 µM, respectively.  

     

    Brand:
    Cayman
    SKU:22162 -

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  • 1-(6-Methoxy-2-naphthyl)ethanol is a potential impurity in commercial preparations of naproxen.{38232} Naproxen (Item No. 70290) is a non-selective COX inhibitor.{1286,1791} The IC50 values for human recombinant COX-1 and -2 are 0.6-4.8 µM and 2.0-28.4 µM, respectively.  

     

    Brand:
    Cayman
    SKU:22162 -

    Out of stock

  • 1-(6-Methoxy-2-naphthyl)ethanol is a potential impurity in commercial preparations of naproxen.{38232} Naproxen (Item No. 70290) is a non-selective COX inhibitor.{1286,1791} The IC50 values for human recombinant COX-1 and -2 are 0.6-4.8 µM and 2.0-28.4 µM, respectively.  

     

    Brand:
    Cayman
    SKU:22162 -

    Out of stock

  • 1-(Ethoxycarbonylmethyl)-6-methoxyquinolinium (bromide) is a fluorescent indicator dye that can be used to measure intracellular and extracellular chloride concentrations (absorption/emission max: 350/460 nm).{22804} It detects the ion via diffusion-limited collisional quenching.  

     

    Brand:
    Cayman
    SKU:19585 -

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  • 1-(Ethoxycarbonylmethyl)-6-methoxyquinolinium (bromide) is a fluorescent indicator dye that can be used to measure intracellular and extracellular chloride concentrations (absorption/emission max: 350/460 nm).{22804} It detects the ion via diffusion-limited collisional quenching.  

     

    Brand:
    Cayman
    SKU:19585 -

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  • 1-(Ethoxycarbonylmethyl)-6-methoxyquinolinium (bromide) is a fluorescent indicator dye that can be used to measure intracellular and extracellular chloride concentrations (absorption/emission max: 350/460 nm).{22804} It detects the ion via diffusion-limited collisional quenching.  

     

    Brand:
    Cayman
    SKU:19585 -

    Available on backorder

  • 1-(Ethoxycarbonylmethyl)-6-methoxyquinolinium (bromide) is a fluorescent indicator dye that can be used to measure intracellular and extracellular chloride concentrations (absorption/emission max: 350/460 nm).{22804} It detects the ion via diffusion-limited collisional quenching.  

     

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    Cayman
    SKU:19585 -

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  • 1-1(Z)-Hexadecenyl-2-palmitoyl-sn-glycero-3-PC is a plasmalogen that has been found in various rat tissues, including the liver, heart, kidney, gluteus muscle, soleus muscle, and visceral and subcutaneous adipose tissue.{52046} It has been used in the synthesis of lipid bilayers to quantify the effects of amphiphilic compounds, such as lysophosphatidylcholine (1-palmitoyl-2-hydroxy-sn-glycero-3-PC; Item No. 10172) and lysoplasmenylcholine, on membrane dynamics.{52047}  

     

    Brand:
    Cayman
    SKU:28348 - 1 mg

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  • 1-1(Z)-Hexadecenyl-2-palmitoyl-sn-glycero-3-PC is a plasmalogen that has been found in various rat tissues, including the liver, heart, kidney, gluteus muscle, soleus muscle, and visceral and subcutaneous adipose tissue.{52046} It has been used in the synthesis of lipid bilayers to quantify the effects of amphiphilic compounds, such as lysophosphatidylcholine (1-palmitoyl-2-hydroxy-sn-glycero-3-PC; Item No. 10172) and lysoplasmenylcholine, on membrane dynamics.{52047}  

     

    Brand:
    Cayman
    SKU:28348 - 25 mg

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  • 1-1(Z)-Hexadecenyl-2-palmitoyl-sn-glycero-3-PC is a plasmalogen that has been found in various rat tissues, including the liver, heart, kidney, gluteus muscle, soleus muscle, and visceral and subcutaneous adipose tissue.{52046} It has been used in the synthesis of lipid bilayers to quantify the effects of amphiphilic compounds, such as lysophosphatidylcholine (1-palmitoyl-2-hydroxy-sn-glycero-3-PC; Item No. 10172) and lysoplasmenylcholine, on membrane dynamics.{52047}  

     

    Brand:
    Cayman
    SKU:28348 - 5 mg

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  • 1-1(Z)-Hexadecenyl-2-palmitoyl-sn-glycero-3-PE is a plasmalogen that contains 1(Z)-hexadecanoic acid and palmitic acid (Item No. 10006627) at the sn-1 and sn-2 positions, respectively.  

     

    Brand:
    Cayman
    SKU:28349 - 1 mg

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  • 1-1(Z)-Hexadecenyl-2-palmitoyl-sn-glycero-3-PE is a plasmalogen that contains 1(Z)-hexadecanoic acid and palmitic acid (Item No. 10006627) at the sn-1 and sn-2 positions, respectively.  

     

    Brand:
    Cayman
    SKU:28349 - 5 mg

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  • 1-1(Z)-Hexadecenyl-2-palmitoyl-sn-glycero-3-PE is a plasmalogen that contains 1(Z)-hexadecanoic acid and palmitic acid (Item No. 10006627) at the sn-1 and sn-2 positions, respectively.  

     

    Brand:
    Cayman
    SKU:28349 - 500 µg

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  • 1-Alaninechlamydocin is a fungal metabolite originally isolated from a Great Lakes-derived Tolypocladium sp. and an inhibitor of histone deacetylases (HDACs).{46278} It reduces total HDAC activity in HeLa cell lysates in a concentration-dependent manner. 1-Alaninechlamydocin reduces proliferation of MIA PaCa-2, PANC-1, and hTERT-HPNE cells (GI50s = 5.3, 14, and 2.0 nM, respectively).  

     

    Brand:
    Cayman
    SKU:28102 - 2.5 mg

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  • 1-Alaninechlamydocin is a fungal metabolite originally isolated from a Great Lakes-derived Tolypocladium sp. and an inhibitor of histone deacetylases (HDACs).{46278} It reduces total HDAC activity in HeLa cell lysates in a concentration-dependent manner. 1-Alaninechlamydocin reduces proliferation of MIA PaCa-2, PANC-1, and hTERT-HPNE cells (GI50s = 5.3, 14, and 2.0 nM, respectively).  

     

    Brand:
    Cayman
    SKU:28102 - 500 µg

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  • 1-Amino-1-deoxy-D-fructose is an amino monosaccharide.{53651} It induces site-specific DNA damage at pyrimidine residues in cell-free assays. 1-Amino-1-deoxy-D-fructose moieties have been found as a component of fructosamines, glycated serum proteins that are elevated in patients with conditions such as diabetes.{53652,53653}  

     

    Brand:
    Cayman
    SKU:30571 - 100 mg

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  • 1-Amino-1-deoxy-D-fructose is an amino monosaccharide.{53651} It induces site-specific DNA damage at pyrimidine residues in cell-free assays. 1-Amino-1-deoxy-D-fructose moieties have been found as a component of fructosamines, glycated serum proteins that are elevated in patients with conditions such as diabetes.{53652,53653}  

     

    Brand:
    Cayman
    SKU:30571 - 250 mg

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  • 1-Amino-1-deoxy-D-fructose is an amino monosaccharide.{53651} It induces site-specific DNA damage at pyrimidine residues in cell-free assays. 1-Amino-1-deoxy-D-fructose moieties have been found as a component of fructosamines, glycated serum proteins that are elevated in patients with conditions such as diabetes.{53652,53653}  

     

    Brand:
    Cayman
    SKU:30571 - 50 mg

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  • 1-Amino-1-deoxy-D-fructose is an amino monosaccharide.{53651} It induces site-specific DNA damage at pyrimidine residues in cell-free assays. 1-Amino-1-deoxy-D-fructose moieties have been found as a component of fructosamines, glycated serum proteins that are elevated in patients with conditions such as diabetes.{53652,53653}  

     

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    Cayman
    SKU:30571 - 500 mg

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  • 1-aminobenzotriazole (ABT) is a non-specific cytochrome P450 (CYP) inhibitor.{32434,32435,24115} It does not appear to affect other enzymes, including UDP-glucuronosyltransferases.{32436,20875} ABT acts as a CYP suicide substrate, producing maximal destruction of hepatic and renal microsome CYP protein in vitro at 10 mM.{32436} It is effective in vivo, significantly reducing CYP content in both liver and kidney in rats within two hours.{32436} The effects of ABT on CYP activity is time-dependent, with significant shift in IC50 values with preincubation.{24115}  

     

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    Cayman
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  • 1-aminobenzotriazole (ABT) is a non-specific cytochrome P450 (CYP) inhibitor.{32434,32435,24115} It does not appear to affect other enzymes, including UDP-glucuronosyltransferases.{32436,20875} ABT acts as a CYP suicide substrate, producing maximal destruction of hepatic and renal microsome CYP protein in vitro at 10 mM.{32436} It is effective in vivo, significantly reducing CYP content in both liver and kidney in rats within two hours.{32436} The effects of ABT on CYP activity is time-dependent, with significant shift in IC50 values with preincubation.{24115}  

     

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    Cayman
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  • 1-aminobenzotriazole (ABT) is a non-specific cytochrome P450 (CYP) inhibitor.{32434,32435,24115} It does not appear to affect other enzymes, including UDP-glucuronosyltransferases.{32436,20875} ABT acts as a CYP suicide substrate, producing maximal destruction of hepatic and renal microsome CYP protein in vitro at 10 mM.{32436} It is effective in vivo, significantly reducing CYP content in both liver and kidney in rats within two hours.{32436} The effects of ABT on CYP activity is time-dependent, with significant shift in IC50 values with preincubation.{24115}  

     

    Brand:
    Cayman
    SKU:-
  • 1-aminobenzotriazole (ABT) is a non-specific cytochrome P450 (CYP) inhibitor.{32434,32435,24115} It does not appear to affect other enzymes, including UDP-glucuronosyltransferases.{32436,20875} ABT acts as a CYP suicide substrate, producing maximal destruction of hepatic and renal microsome CYP protein in vitro at 10 mM.{32436} It is effective in vivo, significantly reducing CYP content in both liver and kidney in rats within two hours.{32436} The effects of ABT on CYP activity is time-dependent, with significant shift in IC50 values with preincubation.{24115}  

     

    Brand:
    Cayman
    SKU:-
  • 1-Aminocyclopropanecarboxylic acid (ACPC) is an intermediate in the synthesis of ethylene, the plant hormone responsible for biological processes ranging from seed germination to organ senescence.{26310} ACPC has been shown to modulate NMDA receptor activity by acting as a partial agonist at the glycine-binding site on NMDA receptors (EC50 = 0.7-0.9 µM) in the presence of low levels (1 µM) of glutamate and as a competitive antagonist at the glutamate-binding site on NMDA receptors (EC50 = 81.6 nM) with high levels (10 µM) of glutamate.{26311} This compound has been reported to protect against neuron cell death in in vivo models of ischemia by enabling moderate levels of NMDA receptor activation and attenuating any excess NMDA receptor signaling that may lead to neurotoxicity.{26311}  

     

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    Cayman
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  • 1-Aminocyclopropanecarboxylic acid (ACPC) is an intermediate in the synthesis of ethylene, the plant hormone responsible for biological processes ranging from seed germination to organ senescence.{26310} ACPC has been shown to modulate NMDA receptor activity by acting as a partial agonist at the glycine-binding site on NMDA receptors (EC50 = 0.7-0.9 µM) in the presence of low levels (1 µM) of glutamate and as a competitive antagonist at the glutamate-binding site on NMDA receptors (EC50 = 81.6 nM) with high levels (10 µM) of glutamate.{26311} This compound has been reported to protect against neuron cell death in in vivo models of ischemia by enabling moderate levels of NMDA receptor activation and attenuating any excess NMDA receptor signaling that may lead to neurotoxicity.{26311}  

     

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    Cayman
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  • 1-Aminocyclopropanecarboxylic acid (ACPC) is an intermediate in the synthesis of ethylene, the plant hormone responsible for biological processes ranging from seed germination to organ senescence.{26310} ACPC has been shown to modulate NMDA receptor activity by acting as a partial agonist at the glycine-binding site on NMDA receptors (EC50 = 0.7-0.9 µM) in the presence of low levels (1 µM) of glutamate and as a competitive antagonist at the glutamate-binding site on NMDA receptors (EC50 = 81.6 nM) with high levels (10 µM) of glutamate.{26311} This compound has been reported to protect against neuron cell death in in vivo models of ischemia by enabling moderate levels of NMDA receptor activation and attenuating any excess NMDA receptor signaling that may lead to neurotoxicity.{26311}  

     

    Brand:
    Cayman
    SKU:-
  • 1-Aminocyclopropanecarboxylic acid (ACPC) is an intermediate in the synthesis of ethylene, the plant hormone responsible for biological processes ranging from seed germination to organ senescence.{26310} ACPC has been shown to modulate NMDA receptor activity by acting as a partial agonist at the glycine-binding site on NMDA receptors (EC50 = 0.7-0.9 µM) in the presence of low levels (1 µM) of glutamate and as a competitive antagonist at the glutamate-binding site on NMDA receptors (EC50 = 81.6 nM) with high levels (10 µM) of glutamate.{26311} This compound has been reported to protect against neuron cell death in in vivo models of ischemia by enabling moderate levels of NMDA receptor activation and attenuating any excess NMDA receptor signaling that may lead to neurotoxicity.{26311}  

     

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    Cayman
    SKU:-
  • The glyceryl esters of arachidonic acid have been proposed as endogenous cannabinoid ligands.{4614} 2-AG is 10 to 100 times more potent than 1-AG in ligand binding affinity and agonist activity at the CB1 receptor, and is thus considered to be the natural ligand.{5306} However, 2-AG is chemically unstable and undergoes rapid isomerization to 1-AG (synonymous with 1(3)-AG) both in vitro and in vivo. 1-AG is a frequent contaminant in synthetic 2-AG preparations, and can markedly reduce their cannabinergic potency. 1-AG is a weak CB1 receptor agonist and may have other pharmacologic properties.  

     

    Brand:
    Cayman
    SKU:62150 - 1 mg

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  • The glyceryl esters of arachidonic acid have been proposed as endogenous cannabinoid ligands.{4614} 2-AG is 10 to 100 times more potent than 1-AG in ligand binding affinity and agonist activity at the CB1 receptor, and is thus considered to be the natural ligand.{5306} However, 2-AG is chemically unstable and undergoes rapid isomerization to 1-AG (synonymous with 1(3)-AG) both in vitro and in vivo. 1-AG is a frequent contaminant in synthetic 2-AG preparations, and can markedly reduce their cannabinergic potency. 1-AG is a weak CB1 receptor agonist and may have other pharmacologic properties.  

     

    Brand:
    Cayman
    SKU:62150 - 10 mg

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  • The glyceryl esters of arachidonic acid have been proposed as endogenous cannabinoid ligands.{4614} 2-AG is 10 to 100 times more potent than 1-AG in ligand binding affinity and agonist activity at the CB1 receptor, and is thus considered to be the natural ligand.{5306} However, 2-AG is chemically unstable and undergoes rapid isomerization to 1-AG (synonymous with 1(3)-AG) both in vitro and in vivo. 1-AG is a frequent contaminant in synthetic 2-AG preparations, and can markedly reduce their cannabinergic potency. 1-AG is a weak CB1 receptor agonist and may have other pharmacologic properties.  

     

    Brand:
    Cayman
    SKU:62150 - 25 mg

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  • The glyceryl esters of arachidonic acid have been proposed as endogenous cannabinoid ligands.{4614} 2-AG is 10 to 100 times more potent than 1-AG in ligand binding affinity and agonist activity at the CB1 receptor, and is thus considered to be the natural ligand.{5306} However, 2-AG is chemically unstable and undergoes rapid isomerization to 1-AG (synonymous with 1(3)-AG) both in vitro and in vivo. 1-AG is a frequent contaminant in synthetic 2-AG preparations, and can markedly reduce their cannabinergic potency. 1-AG is a weak CB1 receptor agonist and may have other pharmacologic properties.  

     

    Brand:
    Cayman
    SKU:62150 - 5 mg

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  • 1-Arachidonoyl lysophosphatidic acid is a phospholipid containing arachidonic acid at the sn-1 position. It has been found in rat brain as 37% of the arachidonic acid-containing lysophosphatidic acid (LPA) species and is a precursor to 1-arachidonoyl glycerol (1-AG; Item No. 62150).{10322} 1-Arachidonoyl lysophosphatidic acid binds to the LPA2/EDG4 receptor with an EC50 value of approximately 10 nM.{43503} It prevents TNF-α and IL-6 secretion in wild-type but not Lpa2-/- dendritic cells stimulated by LPS.{43504} It also decreases differentiation of HT-29 human colon carcinoma cells to goblet cells in the presence of sodium butyrate.{43505}  

     

    Brand:
    Cayman
    SKU:10019 - 1 mg

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  • 1-Arachidonoyl lysophosphatidic acid is a phospholipid containing arachidonic acid at the sn-1 position. It has been found in rat brain as 37% of the arachidonic acid-containing lysophosphatidic acid (LPA) species and is a precursor to 1-arachidonoyl glycerol (1-AG; Item No. 62150).{10322} 1-Arachidonoyl lysophosphatidic acid binds to the LPA2/EDG4 receptor with an EC50 value of approximately 10 nM.{43503} It prevents TNF-α and IL-6 secretion in wild-type but not Lpa2-/- dendritic cells stimulated by LPS.{43504} It also decreases differentiation of HT-29 human colon carcinoma cells to goblet cells in the presence of sodium butyrate.{43505}  

     

    Brand:
    Cayman
    SKU:10019 - 10 mg

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  • 1-Arachidonoyl lysophosphatidic acid is a phospholipid containing arachidonic acid at the sn-1 position. It has been found in rat brain as 37% of the arachidonic acid-containing lysophosphatidic acid (LPA) species and is a precursor to 1-arachidonoyl glycerol (1-AG; Item No. 62150).{10322} 1-Arachidonoyl lysophosphatidic acid binds to the LPA2/EDG4 receptor with an EC50 value of approximately 10 nM.{43503} It prevents TNF-α and IL-6 secretion in wild-type but not Lpa2-/- dendritic cells stimulated by LPS.{43504} It also decreases differentiation of HT-29 human colon carcinoma cells to goblet cells in the presence of sodium butyrate.{43505}  

     

    Brand:
    Cayman
    SKU:10019 - 5 mg

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  • 1-Arachidonoyl lysophosphatidic acid is a phospholipid containing arachidonic acid at the sn-1 position. It has been found in rat brain as 37% of the arachidonic acid-containing lysophosphatidic acid (LPA) species and is a precursor to 1-arachidonoyl glycerol (1-AG; Item No. 62150).{10322} 1-Arachidonoyl lysophosphatidic acid binds to the LPA2/EDG4 receptor with an EC50 value of approximately 10 nM.{43503} It prevents TNF-α and IL-6 secretion in wild-type but not Lpa2-/- dendritic cells stimulated by LPS.{43504} It also decreases differentiation of HT-29 human colon carcinoma cells to goblet cells in the presence of sodium butyrate.{43505}  

     

    Brand:
    Cayman
    SKU:10019 - 500 µg

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  • 1-Arachidoyl-2-oleoyl-3-palmitoyl-rac-glycerol is a triacylglycerol that contains arachidic acid (Item Nos. 9000339 | 21906), oleic acid (Item Nos. 90260 | 24659), and palmitic acid (Item No. 10006627) at the sn-1, sn-2, and sn-3 positions, respectively. It has been found in a variety of plant oils, including poppy seed, hazelnut, maize, olive, yellow melon, and date seed oils.{49107,49047}  

     

    Brand:
    Cayman
    SKU:28556 - 1 mg

    Available on backorder

  • 1-Arachidoyl-2-oleoyl-3-palmitoyl-rac-glycerol is a triacylglycerol that contains arachidic acid (Item Nos. 9000339 | 21906), oleic acid (Item Nos. 90260 | 24659), and palmitic acid (Item No. 10006627) at the sn-1, sn-2, and sn-3 positions, respectively. It has been found in a variety of plant oils, including poppy seed, hazelnut, maize, olive, yellow melon, and date seed oils.{49107,49047}  

     

    Brand:
    Cayman
    SKU:28556 - 10 mg

    Available on backorder

  • 1-Arachidoyl-2-oleoyl-3-palmitoyl-rac-glycerol is a triacylglycerol that contains arachidic acid (Item Nos. 9000339 | 21906), oleic acid (Item Nos. 90260 | 24659), and palmitic acid (Item No. 10006627) at the sn-1, sn-2, and sn-3 positions, respectively. It has been found in a variety of plant oils, including poppy seed, hazelnut, maize, olive, yellow melon, and date seed oils.{49107,49047}  

     

    Brand:
    Cayman
    SKU:28556 - 5 mg

    Available on backorder

  • 1-Arachidoyl-2-palmitoyl-3-oleoyl-rac-glycerol is a triacylglycerol that contains arachidic acid (Item Nos. 9000339 | 21906), palmitic acid (Item No. 10006627), and oleic acid (Item Nos. 90260 | 24659) at the sn-1, sn-2, and sn-3 positions, respectively. It has been found in butterfat.{46189} Liver levels of 1-arachidoyl-2-palmitoyl-3-oleoyl-rac-glycerol are increased in Plin5-overexpressing mice fed a high-fat diet.{53077}  

     

    Brand:
    Cayman
    SKU:28555 - 1 mg

    Available on backorder

  • 1-Arachidoyl-2-palmitoyl-3-oleoyl-rac-glycerol is a triacylglycerol that contains arachidic acid (Item Nos. 9000339 | 21906), palmitic acid (Item No. 10006627), and oleic acid (Item Nos. 90260 | 24659) at the sn-1, sn-2, and sn-3 positions, respectively. It has been found in butterfat.{46189} Liver levels of 1-arachidoyl-2-palmitoyl-3-oleoyl-rac-glycerol are increased in Plin5-overexpressing mice fed a high-fat diet.{53077}  

     

    Brand:
    Cayman
    SKU:28555 - 10 mg

    Available on backorder

  • 1-Arachidoyl-2-palmitoyl-3-oleoyl-rac-glycerol is a triacylglycerol that contains arachidic acid (Item Nos. 9000339 | 21906), palmitic acid (Item No. 10006627), and oleic acid (Item Nos. 90260 | 24659) at the sn-1, sn-2, and sn-3 positions, respectively. It has been found in butterfat.{46189} Liver levels of 1-arachidoyl-2-palmitoyl-3-oleoyl-rac-glycerol are increased in Plin5-overexpressing mice fed a high-fat diet.{53077}  

     

    Brand:
    Cayman
    SKU:28555 - 25 mg

    Available on backorder

  • 1-Arachidoyl-2-palmitoyl-3-oleoyl-rac-glycerol is a triacylglycerol that contains arachidic acid (Item Nos. 9000339 | 21906), palmitic acid (Item No. 10006627), and oleic acid (Item Nos. 90260 | 24659) at the sn-1, sn-2, and sn-3 positions, respectively. It has been found in butterfat.{46189} Liver levels of 1-arachidoyl-2-palmitoyl-3-oleoyl-rac-glycerol are increased in Plin5-overexpressing mice fed a high-fat diet.{53077}  

     

    Brand:
    Cayman
    SKU:28555 - 5 mg

    Available on backorder

  • 1-Arachidoyl-rac-glycerol is a monoacylglycerol that contains arachidic acid (Item Nos. 9000339 | 21906) at the sn-1 position. It has been found in pork muscle.{47753}  

     

    Brand:
    Cayman
    SKU:26947 - 100 mg

    Available on backorder

  • 1-Arachidoyl-rac-glycerol is a monoacylglycerol that contains arachidic acid (Item Nos. 9000339 | 21906) at the sn-1 position. It has been found in pork muscle.{47753}  

     

    Brand:
    Cayman
    SKU:26947 - 250 mg

    Available on backorder

  • 1-Arachidoyl-rac-glycerol is a monoacylglycerol that contains arachidic acid (Item Nos. 9000339 | 21906) at the sn-1 position. It has been found in pork muscle.{47753}  

     

    Brand:
    Cayman
    SKU:26947 - 50 mg

    Available on backorder

  • 1-Arachidoyl-rac-glycerol is a monoacylglycerol that contains arachidic acid (Item Nos. 9000339 | 21906) at the sn-1 position. It has been found in pork muscle.{47753}  

     

    Brand:
    Cayman
    SKU:26947 - 500 mg

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  • 1-Azakenpaullone is an analog of kenpaullone (Item No. 10010239) that inhibits glycogen synthase kinase 3β (GSK3β) more potently (IC50 = 18 nM) than CDK1/cyclin B or CDK5/p25 (IC50s = 2.0 and 4.2 µM, respectively).{27328} Through its effects on GSK3β, 1-azakenpaullone stimulates the proliferation of human pancreatic islets and drives the differentiation of mouse embryonic stem cells and Nematostella larvae.{27329,27331,27330}  

     

    Brand:
    Cayman
    SKU:-

    Out of stock

  • 1-Azakenpaullone is an analog of kenpaullone (Item No. 10010239) that inhibits glycogen synthase kinase 3β (GSK3β) more potently (IC50 = 18 nM) than CDK1/cyclin B or CDK5/p25 (IC50s = 2.0 and 4.2 µM, respectively).{27328} Through its effects on GSK3β, 1-azakenpaullone stimulates the proliferation of human pancreatic islets and drives the differentiation of mouse embryonic stem cells and Nematostella larvae.{27329,27331,27330}  

     

    Brand:
    Cayman
    SKU:-

    Out of stock

  • 1-Azakenpaullone is an analog of kenpaullone (Item No. 10010239) that inhibits glycogen synthase kinase 3β (GSK3β) more potently (IC50 = 18 nM) than CDK1/cyclin B or CDK5/p25 (IC50s = 2.0 and 4.2 µM, respectively).{27328} Through its effects on GSK3β, 1-azakenpaullone stimulates the proliferation of human pancreatic islets and drives the differentiation of mouse embryonic stem cells and Nematostella larvae.{27329,27331,27330}  

     

    Brand:
    Cayman
    SKU:-

    Out of stock

  • 1-Benzyl-2-methylpiperazine (hydrochloride) (Item No. 23708) is an analytical reference standard categorized as a piperazine. This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:23708 - 1 mg

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  • 1-Benzyl-2-methylpiperazine (hydrochloride) (Item No. 23708) is an analytical reference standard categorized as a piperazine. This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:23708 - 5 mg

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  • 1-Benzyl-3-methylpiperazine (Item No. 23709) is an analytical reference standard categorized as a piperazine. This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:23709 - 1 mg

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  • 1-Benzyl-3-methylpiperazine (Item No. 23709) is an analytical reference standard categorized as a piperazine. This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:23709 - 5 mg

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  • 1-Benzylimidazole is a selective inhibitor of thromboxane synthase. It reduces TXB2 levels and increases blood flow in ischemia-reperfusion injury of rat brain.{2001}  

     

    Brand:
    Cayman
    SKU:70510 - 10 g

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  • 1-Benzylimidazole is a selective inhibitor of thromboxane synthase. It reduces TXB2 levels and increases blood flow in ischemia-reperfusion injury of rat brain.{2001}  

     

    Brand:
    Cayman
    SKU:70510 - 25 g

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  • 1-Benzylimidazole is a selective inhibitor of thromboxane synthase. It reduces TXB2 levels and increases blood flow in ischemia-reperfusion injury of rat brain.{2001}  

     

    Brand:
    Cayman
    SKU:70510 - 5 g

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  • 1-Decanoyl-rac-glycerol is a monoacylglycerol that contains decanoic acid (Item No. 20838) at the sn-1 position. It inhibits the growth of B. cereus, S. typhimurium, and E. coli when used at a concentration of 1 mg/ml and S. aureus when used at a concentration of 0.5 mg/ml.{49108} 1-Decanoyl-rac-glycerol is an agonist of transient receptor potential vanilloid 1 (TRPV1) that induces calcium influx in HEK293 cells expressing the human receptor (EC50 = 12.6 μM).{49109} It is an emulsifying agent and has been used to increase the storage stability of mayonnaise and viscoelasticity of processed cheese.{49110,49111}  

     

    Brand:
    Cayman
    SKU:26888 - 100 mg

    Available on backorder

  • 1-Decanoyl-rac-glycerol is a monoacylglycerol that contains decanoic acid (Item No. 20838) at the sn-1 position. It inhibits the growth of B. cereus, S. typhimurium, and E. coli when used at a concentration of 1 mg/ml and S. aureus when used at a concentration of 0.5 mg/ml.{49108} 1-Decanoyl-rac-glycerol is an agonist of transient receptor potential vanilloid 1 (TRPV1) that induces calcium influx in HEK293 cells expressing the human receptor (EC50 = 12.6 μM).{49109} It is an emulsifying agent and has been used to increase the storage stability of mayonnaise and viscoelasticity of processed cheese.{49110,49111}  

     

    Brand:
    Cayman
    SKU:26888 - 50 mg

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  • 1-demethyl Phenazolam (Item No. 23525) is an analytical reference standard categorized as a benzodiazepine. This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:23525 - 1 mg

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  • 1-demethyl Phenazolam (Item No. 23525) is an analytical reference standard categorized as a benzodiazepine. This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:23525 - 5 mg

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  • Fabry disease is an X-linked hereditary lysosomal storage disorder caused by mutations in the α-galactosidase gene that commonly lead to enzyme instability, misfolding, and degradation.{28086,28087} 1-Deoxygalactonojirimycin is a competititve inhibitor of α-galactosidase (IC50 = 40 nM).{28089} At subinhibitory concentrations, 1-Deoxygalactonojirimycin binds to α-galactosidase and chaperones unstable enzyme variants through the endoplasmic reticulum, allowing its movement into lysosomes.{28088,28086} Pharmacological chaperones, including 1-Deoxygalactonojirimycin, are used to promote lysosomal delivery of unstable proteins in lysosomal storage disorders, like Fabry disease.{28086}  

     

    Brand:
    Cayman
    SKU:-

    Out of stock

  • Fabry disease is an X-linked hereditary lysosomal storage disorder caused by mutations in the α-galactosidase gene that commonly lead to enzyme instability, misfolding, and degradation.{28086,28087} 1-Deoxygalactonojirimycin is a competititve inhibitor of α-galactosidase (IC50 = 40 nM).{28089} At subinhibitory concentrations, 1-Deoxygalactonojirimycin binds to α-galactosidase and chaperones unstable enzyme variants through the endoplasmic reticulum, allowing its movement into lysosomes.{28088,28086} Pharmacological chaperones, including 1-Deoxygalactonojirimycin, are used to promote lysosomal delivery of unstable proteins in lysosomal storage disorders, like Fabry disease.{28086}  

     

    Brand:
    Cayman
    SKU:-

    Out of stock

  • Fabry disease is an X-linked hereditary lysosomal storage disorder caused by mutations in the α-galactosidase gene that commonly lead to enzyme instability, misfolding, and degradation.{28086,28087} 1-Deoxygalactonojirimycin is a competititve inhibitor of α-galactosidase (IC50 = 40 nM).{28089} At subinhibitory concentrations, 1-Deoxygalactonojirimycin binds to α-galactosidase and chaperones unstable enzyme variants through the endoplasmic reticulum, allowing its movement into lysosomes.{28088,28086} Pharmacological chaperones, including 1-Deoxygalactonojirimycin, are used to promote lysosomal delivery of unstable proteins in lysosomal storage disorders, like Fabry disease.{28086}  

     

    Brand:
    Cayman
    SKU:-

    Out of stock

  • 1-Deoxymannojirimycin is a specific inhibitor of class I α-1,2-mannosidase (IC50 = 0.02 µM), a key enzyme for N-glycan processing in the endoplasmic reticulum and Golgi and for targeting misfolded proteins for translocation out of the endoplasmic reticulum and degradation by the proteasome.{28144,28145} By inhibiting α-1,2-mannosidase activity, this compound generates N-linked oligosaccharides with high mannose content, preventing misfolded protein degradation. This compound has been used for studies on glycoprotein processing and as a model for the development of anticancer and antiviral therapies.{28146,28147}  

     

    Brand:
    Cayman
    SKU:-

    Out of stock

  • 1-Deoxymannojirimycin is a specific inhibitor of class I α-1,2-mannosidase (IC50 = 0.02 µM), a key enzyme for N-glycan processing in the endoplasmic reticulum and Golgi and for targeting misfolded proteins for translocation out of the endoplasmic reticulum and degradation by the proteasome.{28144,28145} By inhibiting α-1,2-mannosidase activity, this compound generates N-linked oligosaccharides with high mannose content, preventing misfolded protein degradation. This compound has been used for studies on glycoprotein processing and as a model for the development of anticancer and antiviral therapies.{28146,28147}  

     

    Brand:
    Cayman
    SKU:-

    Out of stock

  • 1-Deoxymannojirimycin is a specific inhibitor of class I α-1,2-mannosidase (IC50 = 0.02 µM), a key enzyme for N-glycan processing in the endoplasmic reticulum and Golgi and for targeting misfolded proteins for translocation out of the endoplasmic reticulum and degradation by the proteasome.{28144,28145} By inhibiting α-1,2-mannosidase activity, this compound generates N-linked oligosaccharides with high mannose content, preventing misfolded protein degradation. This compound has been used for studies on glycoprotein processing and as a model for the development of anticancer and antiviral therapies.{28146,28147}  

     

    Brand:
    Cayman
    SKU:-

    Out of stock

  • 1-Deoxymannojirimycin is a specific inhibitor of class I α-1,2-mannosidase (IC50 = 0.02 µM), a key enzyme for N-glycan processing in the endoplasmic reticulum and Golgi and for targeting misfolded proteins for translocation out of the endoplasmic reticulum and degradation by the proteasome.{28144,28145} By inhibiting α-1,2-mannosidase activity, this compound generates N-linked oligosaccharides with high mannose content, preventing misfolded protein degradation. This compound has been used for studies on glycoprotein processing and as a model for the development of anticancer and antiviral therapies.{28146,28147}  

     

    Brand:
    Cayman
    SKU:-

    Out of stock

  • 1-Deoxynojirimycin (1-dNM), produced by Bacillus species, is a glucose analog that potently inhibits α-glucosidase I and II. It prevents the formation of complex N-linked oligosaccharides in yeast and intact mammalian cells by inhibiting both α-glucosidase I and II with IC50 values of ~2 µM.{16271,16267} 1-dNM, at a concentration of 0.4 mM, is reported to inhibit virus spread in HIV-infected lymphocyte cultures by interfering with α-glucosidase activity.{16269,16270}  

     

    Brand:
    Cayman
    SKU:21500 -

    Out of stock

  • 1-Deoxynojirimycin (1-dNM), produced by Bacillus species, is a glucose analog that potently inhibits α-glucosidase I and II. It prevents the formation of complex N-linked oligosaccharides in yeast and intact mammalian cells by inhibiting both α-glucosidase I and II with IC50 values of ~2 µM.{16271,16267} 1-dNM, at a concentration of 0.4 mM, is reported to inhibit virus spread in HIV-infected lymphocyte cultures by interfering with α-glucosidase activity.{16269,16270}  

     

    Brand:
    Cayman
    SKU:21500 -

    Out of stock

  • 1-Deoxynojirimycin (1-dNM), produced by Bacillus species, is a glucose analog that potently inhibits α-glucosidase I and II. It prevents the formation of complex N-linked oligosaccharides in yeast and intact mammalian cells by inhibiting both α-glucosidase I and II with IC50 values of ~2 µM.{16271,16267} 1-dNM, at a concentration of 0.4 mM, is reported to inhibit virus spread in HIV-infected lymphocyte cultures by interfering with α-glucosidase activity.{16269,16270}  

     

    Brand:
    Cayman
    SKU:21500 -

    Out of stock

  • 1-Deoxynojirimycin (1-dNM), produced by Bacillus species, is a glucose analog that potently inhibits α-glucosidase I and II. It prevents the formation of complex N-linked oligosaccharides in yeast and intact mammalian cells by inhibiting both α-glucosidase I and II with IC50 values of ~2 µM.{16271,16267} 1-dNM, at a concentration of 0.4 mM, is reported to inhibit virus spread in HIV-infected lymphocyte cultures by interfering with α-glucosidase activity.{16269,16270}  

     

    Brand:
    Cayman
    SKU:21500 -

    Out of stock

  • 1-Deoxynojirimycin (1-dNM) (hydrochloride), produced by Bacillus species, is a glucose analog that potently inhibits α-glucosidase I and II. It prevents the formation of complex N-linked oligosaccharides in yeast and intact mammalian cells by inhibiting both α-glucosidase I and II with IC50 values of ~2 µM.{16271,16267} The FDA has granted orphan drug designation to dNM (hydrochloride) for the treatment of Pompe disease, an inherited lysosomal storage disorder caused by a mutation that alters the structure and stability of α-glucosidase. 1-dNM, at a concentration of 0.4 mM, also inhibits virus spread in HIV-infected lymphocyte cultures by interfering with α-glucosidase activity.{16269,16270}  

     

    Brand:
    Cayman
    SKU:10011718 - 1 mg

    Available on backorder

  • 1-Deoxynojirimycin (1-dNM) (hydrochloride), produced by Bacillus species, is a glucose analog that potently inhibits α-glucosidase I and II. It prevents the formation of complex N-linked oligosaccharides in yeast and intact mammalian cells by inhibiting both α-glucosidase I and II with IC50 values of ~2 µM.{16271,16267} The FDA has granted orphan drug designation to dNM (hydrochloride) for the treatment of Pompe disease, an inherited lysosomal storage disorder caused by a mutation that alters the structure and stability of α-glucosidase. 1-dNM, at a concentration of 0.4 mM, also inhibits virus spread in HIV-infected lymphocyte cultures by interfering with α-glucosidase activity.{16269,16270}  

     

    Brand:
    Cayman
    SKU:10011718 - 10 mg

    Available on backorder

  • 1-Deoxynojirimycin (1-dNM) (hydrochloride), produced by Bacillus species, is a glucose analog that potently inhibits α-glucosidase I and II. It prevents the formation of complex N-linked oligosaccharides in yeast and intact mammalian cells by inhibiting both α-glucosidase I and II with IC50 values of ~2 µM.{16271,16267} The FDA has granted orphan drug designation to dNM (hydrochloride) for the treatment of Pompe disease, an inherited lysosomal storage disorder caused by a mutation that alters the structure and stability of α-glucosidase. 1-dNM, at a concentration of 0.4 mM, also inhibits virus spread in HIV-infected lymphocyte cultures by interfering with α-glucosidase activity.{16269,16270}  

     

    Brand:
    Cayman
    SKU:10011718 - 5 mg

    Available on backorder

  • 1-Deoxynojirimycin (1-dNM) (hydrochloride), produced by Bacillus species, is a glucose analog that potently inhibits α-glucosidase I and II. It prevents the formation of complex N-linked oligosaccharides in yeast and intact mammalian cells by inhibiting both α-glucosidase I and II with IC50 values of ~2 µM.{16271,16267} The FDA has granted orphan drug designation to dNM (hydrochloride) for the treatment of Pompe disease, an inherited lysosomal storage disorder caused by a mutation that alters the structure and stability of α-glucosidase. 1-dNM, at a concentration of 0.4 mM, also inhibits virus spread in HIV-infected lymphocyte cultures by interfering with α-glucosidase activity.{16269,16270}  

     

    Brand:
    Cayman
    SKU:10011718 - 50 mg

    Available on backorder

  • 1-Deoxysphinganine is an atypical sphingolipid that lacks the C1-hydroxyl group of canonical sphinganine and is formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis.{17311} Plasma levels of 1-deoxysphinganine are increased in patients with hereditary sensory and autonomic neuropathy type 1 (HSAN1), an inherited neuropathy associated with serine palmitoyltransferase gene mutations, and in patients with glycogen storage disease type I (GSDI).{42288,36918} Deoxysphingolipids, including 1-deoxysphinganine, are not converted to canonical sphingolipids or fatty acids and accumulate in cells, particularly in the mitochondria where 1-deoxysphinganine induces mitochondrial fragmentation and dysfunction.{42285} It also accumulates in LLC-PK1 cells and in mouse liver and kidney following application or administration, respectively, of the ceramide synthase inhibitor fumonisin B1 (Item No. 62580).{17311} 1-Deoxysphinganine is neurotoxic to dorsal root ganglion neurons in vitro, decreasing neurite length and inducing neurite contraction when used at a concentration 1 µM.{42288} It is cytotoxic to DU145 cells (IC50 = ~2 µM) but stimulates DNA synthesis in Swiss 3T3 cells when used at a concentration of 1 µM.{17311,36917}  

     

    Brand:
    Cayman
    SKU:-
  • 1-Deoxysphinganine is an atypical sphingolipid that lacks the C1-hydroxyl group of canonical sphinganine and is formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis.{17311} Plasma levels of 1-deoxysphinganine are increased in patients with hereditary sensory and autonomic neuropathy type 1 (HSAN1), an inherited neuropathy associated with serine palmitoyltransferase gene mutations, and in patients with glycogen storage disease type I (GSDI).{42288,36918} Deoxysphingolipids, including 1-deoxysphinganine, are not converted to canonical sphingolipids or fatty acids and accumulate in cells, particularly in the mitochondria where 1-deoxysphinganine induces mitochondrial fragmentation and dysfunction.{42285} It also accumulates in LLC-PK1 cells and in mouse liver and kidney following application or administration, respectively, of the ceramide synthase inhibitor fumonisin B1 (Item No. 62580).{17311} 1-Deoxysphinganine is neurotoxic to dorsal root ganglion neurons in vitro, decreasing neurite length and inducing neurite contraction when used at a concentration 1 µM.{42288} It is cytotoxic to DU145 cells (IC50 = ~2 µM) but stimulates DNA synthesis in Swiss 3T3 cells when used at a concentration of 1 µM.{17311,36917}  

     

    Brand:
    Cayman
    SKU:-
  • 1-Deoxysphinganine is an atypical sphingolipid that lacks the C1-hydroxyl group of canonical sphinganine and is formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis.{17311} Plasma levels of 1-deoxysphinganine are increased in patients with hereditary sensory and autonomic neuropathy type 1 (HSAN1), an inherited neuropathy associated with serine palmitoyltransferase gene mutations, and in patients with glycogen storage disease type I (GSDI).{42288,36918} Deoxysphingolipids, including 1-deoxysphinganine, are not converted to canonical sphingolipids or fatty acids and accumulate in cells, particularly in the mitochondria where 1-deoxysphinganine induces mitochondrial fragmentation and dysfunction.{42285} It also accumulates in LLC-PK1 cells and in mouse liver and kidney following application or administration, respectively, of the ceramide synthase inhibitor fumonisin B1 (Item No. 62580).{17311} 1-Deoxysphinganine is neurotoxic to dorsal root ganglion neurons in vitro, decreasing neurite length and inducing neurite contraction when used at a concentration 1 µM.{42288} It is cytotoxic to DU145 cells (IC50 = ~2 µM) but stimulates DNA synthesis in Swiss 3T3 cells when used at a concentration of 1 µM.{17311,36917}  

     

    Brand:
    Cayman
    SKU:-
  • 1-Deoxysphingosine (m18:1(14Z)) is an atypical sphingolipid that contains a double bond at the n-4 (14Z) native position and is formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis.{40307,42289} It lacks the C1-hydroxyl group necessary for canonical degradation, however, it is metabolized by the cytochrome P450 (CYP) subfamilies CYP4A and CYP4F in MEF cells.{42289}  

     

    Brand:
    Cayman
    SKU:24515 - 1 mg

    Available on backorder

  • 1-Deoxysphingosine (m18:1(14Z)) is an atypical sphingolipid that contains a double bond at the n-4 (14Z) native position and is formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis.{40307,42289} It lacks the C1-hydroxyl group necessary for canonical degradation, however, it is metabolized by the cytochrome P450 (CYP) subfamilies CYP4A and CYP4F in MEF cells.{42289}  

     

    Brand:
    Cayman
    SKU:24515 - 500 µg

    Available on backorder

  • 1-Deoxysphingosine (m18:1(4E)) is an atypical sphingolipid that contains a double bond at the 4E native position and is formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis.{40307,42289} Plasma levels of 1-deoxysphingosine (m18:1(4E)) are increased in patients with chronic idiopathic axonal neuropathy (CIAP) and diabetic distal symmetrical polyneuropathy (DSPN).{53418}  

     

    Brand:
    Cayman
    SKU:24687 - 1 mg

    Available on backorder

  • 1-Deoxysphingosine (m18:1(4E)) is an atypical sphingolipid that contains a double bond at the 4E native position and is formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis.{40307,42289} Plasma levels of 1-deoxysphingosine (m18:1(4E)) are increased in patients with chronic idiopathic axonal neuropathy (CIAP) and diabetic distal symmetrical polyneuropathy (DSPN).{53418}  

     

    Brand:
    Cayman
    SKU:24687 - 500 µg

    Available on backorder

  • 1-EBIO is an activator of Ca2+-sensitive K+ channels (EC50 = 490 µM in T84 human carcinoma cells).{23032} This action is sensitive to the neurotoxin charybdotoxin (Ki = 3.5 nM). In mouse colonic epithelia, 1-EBIO also activates cAMP-sensitive K+ channels, a response this is inhibited by 293B.{23033} In this type of epithelium, but not mouse nasal epithelia, 1-EBIO activates both types of channels, resulting in large Cl- secretory currents.{23029} It also activates the human intermediate conductance Ca2+-activated K+ channel (EC50 = 74 µM).{23030} 1-EBIO is currently used to study the role of these types of K+ channels in diverse physiological functions.{23031,23028}  

     

    Brand:
    Cayman
    SKU:-
  • 1-EBIO is an activator of Ca2+-sensitive K+ channels (EC50 = 490 µM in T84 human carcinoma cells).{23032} This action is sensitive to the neurotoxin charybdotoxin (Ki = 3.5 nM). In mouse colonic epithelia, 1-EBIO also activates cAMP-sensitive K+ channels, a response this is inhibited by 293B.{23033} In this type of epithelium, but not mouse nasal epithelia, 1-EBIO activates both types of channels, resulting in large Cl- secretory currents.{23029} It also activates the human intermediate conductance Ca2+-activated K+ channel (EC50 = 74 µM).{23030} 1-EBIO is currently used to study the role of these types of K+ channels in diverse physiological functions.{23031,23028}  

     

    Brand:
    Cayman
    SKU:-
  • 1-EBIO is an activator of Ca2+-sensitive K+ channels (EC50 = 490 µM in T84 human carcinoma cells).{23032} This action is sensitive to the neurotoxin charybdotoxin (Ki = 3.5 nM). In mouse colonic epithelia, 1-EBIO also activates cAMP-sensitive K+ channels, a response this is inhibited by 293B.{23033} In this type of epithelium, but not mouse nasal epithelia, 1-EBIO activates both types of channels, resulting in large Cl- secretory currents.{23029} It also activates the human intermediate conductance Ca2+-activated K+ channel (EC50 = 74 µM).{23030} 1-EBIO is currently used to study the role of these types of K+ channels in diverse physiological functions.{23031,23028}  

     

    Brand:
    Cayman
    SKU:-
  • 1-EBIO is an activator of Ca2+-sensitive K+ channels (EC50 = 490 µM in T84 human carcinoma cells).{23032} This action is sensitive to the neurotoxin charybdotoxin (Ki = 3.5 nM). In mouse colonic epithelia, 1-EBIO also activates cAMP-sensitive K+ channels, a response this is inhibited by 293B.{23033} In this type of epithelium, but not mouse nasal epithelia, 1-EBIO activates both types of channels, resulting in large Cl- secretory currents.{23029} It also activates the human intermediate conductance Ca2+-activated K+ channel (EC50 = 74 µM).{23030} 1-EBIO is currently used to study the role of these types of K+ channels in diverse physiological functions.{23031,23028}  

     

    Brand:
    Cayman
    SKU:-
  • 1-Heptadecanoyl-rac-glycerol is a monoacylglycerol that contains heptadecanoic acid (Item No. 19722) at the sn-1 position. It is active against the bacteria E. aerogens, E. cloacae, P. mirabilis, and S. faecalis (MIC = 78 µg/ml for all).{45685} 1-Heptadecanoyl-rac-glycerol has been found in T. africana, I. sonorae, and wheat bran.{45685,45686,51025}  

     

    Brand:
    Cayman
    SKU:28180 - 1 mg

    Available on backorder

  • 1-Heptadecanoyl-rac-glycerol is a monoacylglycerol that contains heptadecanoic acid (Item No. 19722) at the sn-1 position. It is active against the bacteria E. aerogens, E. cloacae, P. mirabilis, and S. faecalis (MIC = 78 µg/ml for all).{45685} 1-Heptadecanoyl-rac-glycerol has been found in T. africana, I. sonorae, and wheat bran.{45685,45686,51025}  

     

    Brand:
    Cayman
    SKU:28180 - 10 mg

    Available on backorder

  • 1-Heptadecanoyl-rac-glycerol is a monoacylglycerol that contains heptadecanoic acid (Item No. 19722) at the sn-1 position. It is active against the bacteria E. aerogens, E. cloacae, P. mirabilis, and S. faecalis (MIC = 78 µg/ml for all).{45685} 1-Heptadecanoyl-rac-glycerol has been found in T. africana, I. sonorae, and wheat bran.{45685,45686,51025}  

     

    Brand:
    Cayman
    SKU:28180 - 25 mg

    Available on backorder

  • 1-Heptadecanoyl-rac-glycerol is a monoacylglycerol that contains heptadecanoic acid (Item No. 19722) at the sn-1 position. It is active against the bacteria E. aerogens, E. cloacae, P. mirabilis, and S. faecalis (MIC = 78 µg/ml for all).{45685} 1-Heptadecanoyl-rac-glycerol has been found in T. africana, I. sonorae, and wheat bran.{45685,45686,51025}  

     

    Brand:
    Cayman
    SKU:28180 - 5 mg

    Available on backorder

  • 1-Hexadecyl lysophosphatidic acid is an ether analog of lysophosphatidic acid (LPA) containing a hexadecyl group at the sn-1 position.{15069} LPA binds to five different G protein-coupled receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.{2656,11049}  

     

    Brand:
    Cayman
    SKU:10010188 - 1 mg

    Available on backorder

  • 1-Hexadecyl lysophosphatidic acid is an ether analog of lysophosphatidic acid (LPA) containing a hexadecyl group at the sn-1 position.{15069} LPA binds to five different G protein-coupled receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.{2656,11049}  

     

    Brand:
    Cayman
    SKU:10010188 - 10 mg

    Available on backorder

  • 1-Hexadecyl lysophosphatidic acid is an ether analog of lysophosphatidic acid (LPA) containing a hexadecyl group at the sn-1 position.{15069} LPA binds to five different G protein-coupled receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.{2656,11049}  

     

    Brand:
    Cayman
    SKU:-
  • 1-Hexadecyl lysophosphatidic acid is an ether analog of lysophosphatidic acid (LPA) containing a hexadecyl group at the sn-1 position.{15069} LPA binds to five different G protein-coupled receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.{2656,11049}  

     

    Brand:
    Cayman
    SKU:10010188 - 25 mg

    Available on backorder

  • 1-Hexadecyl lysophosphatidic acid is an ether analog of lysophosphatidic acid (LPA) containing a hexadecyl group at the sn-1 position.{15069} LPA binds to five different G protein-coupled receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.{2656,11049}  

     

    Brand:
    Cayman
    SKU:10010188 - 5 mg

    Available on backorder

  • Vitamin D aids in the absorption of calcium and has central roles in bone formation and maintenance, hypertension, cancer, and immunity.{15096,19429} 1-hydroxy Vitamin D2 is a synthetic prodrug of the active 1,25-dihydroxy vitamin D2 (Item No. 11174), as well as of other active metabolites.{21568} It is used to suppress the synthesis and secretion of parathyroid hormone in secondary hyperparathyroidism, an action which requires vitamin D receptor.{21564,21563,21567} 1-hydroxy Vitamin D2 is effective in stimulating bone growth and, in combination therapy with angiotensin receptor blockers, ameliorates albuminuria and glomerulosclerosis associated with diabetic nephropathy.{21566,21570} It also inhibits the growth of certain blastomas and prostate cancer cells.{21582,21583}  

     

    Brand:
    Cayman
    SKU:12077 - 1 mg

    Available on backorder

  • Vitamin D aids in the absorption of calcium and has central roles in bone formation and maintenance, hypertension, cancer, and immunity.{15096,19429} 1-hydroxy Vitamin D2 is a synthetic prodrug of the active 1,25-dihydroxy vitamin D2 (Item No. 11174), as well as of other active metabolites.{21568} It is used to suppress the synthesis and secretion of parathyroid hormone in secondary hyperparathyroidism, an action which requires vitamin D receptor.{21564,21563,21567} 1-hydroxy Vitamin D2 is effective in stimulating bone growth and, in combination therapy with angiotensin receptor blockers, ameliorates albuminuria and glomerulosclerosis associated with diabetic nephropathy.{21566,21570} It also inhibits the growth of certain blastomas and prostate cancer cells.{21582,21583}  

     

    Brand:
    Cayman
    SKU:12077 - 10 mg

    Available on backorder

  • Vitamin D aids in the absorption of calcium and has central roles in bone formation and maintenance, hypertension, cancer, and immunity.{15096,19429} 1-hydroxy Vitamin D2 is a synthetic prodrug of the active 1,25-dihydroxy vitamin D2 (Item No. 11174), as well as of other active metabolites.{21568} It is used to suppress the synthesis and secretion of parathyroid hormone in secondary hyperparathyroidism, an action which requires vitamin D receptor.{21564,21563,21567} 1-hydroxy Vitamin D2 is effective in stimulating bone growth and, in combination therapy with angiotensin receptor blockers, ameliorates albuminuria and glomerulosclerosis associated with diabetic nephropathy.{21566,21570} It also inhibits the growth of certain blastomas and prostate cancer cells.{21582,21583}  

     

    Brand:
    Cayman
    SKU:12077 - 5 mg

    Available on backorder

  • Vitamin D aids in the absorption of calcium and has central roles in bone formation and maintenance, hypertension, cancer, and immunity.{15096,19429} 1-hydroxy Vitamin D3 is a synthetic prodrug which is converted by cytochrome P450 isoforms to the vitamin D receptor agonist 1,25-dihydroxy vitamin D3 in vivo.{21568,21563} Such prodrugs are effective in suppressing the synthesis and secretion of parathyroid hormone in secondary hyperparathyroidism, an action which requires the vitamin D receptor.{21564,21563,21567} 1-hydroxy Vitamin D3 supports bone growth both in postmenopausal women and in glucocorticoid-induced osteoporosis.{21585,21586} It also provides renal and cardiovascular protection during chronic kidney disease.{21565,21584}  

     

    Brand:
    Cayman
    SKU:12082 - 1 mg

    Available on backorder

  • Vitamin D aids in the absorption of calcium and has central roles in bone formation and maintenance, hypertension, cancer, and immunity.{15096,19429} 1-hydroxy Vitamin D3 is a synthetic prodrug which is converted by cytochrome P450 isoforms to the vitamin D receptor agonist 1,25-dihydroxy vitamin D3 in vivo.{21568,21563} Such prodrugs are effective in suppressing the synthesis and secretion of parathyroid hormone in secondary hyperparathyroidism, an action which requires the vitamin D receptor.{21564,21563,21567} 1-hydroxy Vitamin D3 supports bone growth both in postmenopausal women and in glucocorticoid-induced osteoporosis.{21585,21586} It also provides renal and cardiovascular protection during chronic kidney disease.{21565,21584}  

     

    Brand:
    Cayman
    SKU:12082 - 10 mg

    Available on backorder

  • Vitamin D aids in the absorption of calcium and has central roles in bone formation and maintenance, hypertension, cancer, and immunity.{15096,19429} 1-hydroxy Vitamin D3 is a synthetic prodrug which is converted by cytochrome P450 isoforms to the vitamin D receptor agonist 1,25-dihydroxy vitamin D3 in vivo.{21568,21563} Such prodrugs are effective in suppressing the synthesis and secretion of parathyroid hormone in secondary hyperparathyroidism, an action which requires the vitamin D receptor.{21564,21563,21567} 1-hydroxy Vitamin D3 supports bone growth both in postmenopausal women and in glucocorticoid-induced osteoporosis.{21585,21586} It also provides renal and cardiovascular protection during chronic kidney disease.{21565,21584}  

     

    Brand:
    Cayman
    SKU:12082 - 5 mg

    Available on backorder

  • 1-Hydroxyphenazine is a phenazine pigment and virulence factor produced by P. aeruginosa.{42947,42948} It increases production of reactive oxygen species (ROS) in RAW 264.7 cells in a concentration-dependent manner.{42948} 1-Hydroxyphenazine (≥1.55 and ≥3.12 μM) increases release of elastase and myeloperoxidase (MPO), respectively, by human neutrophils activated with N-formyl-L-methionyl-L-leucyl-L-phenylalanine (fMLP; Item No. 21495) and cytochalasin B (Item No. 11328).{42947} It reduces ciliary beat frequency in isolated guinea pig tracheal rings, resulting in ciliary dyskinesia by 1 hour when used at concentrations of 10, 50, and 100 μM and ciliary stasis by 5 hours at 50 and 100 μM.{42949} 1-Hydroxyphenazine reduces tracheal mucus velocity in anesthetized guinea pigs when administered as a 100 or 200 ng bolus dose. It is also active against the plant pathogenic fungi F. graminearum, P. grisea, A. solani, F. oxysporium, and S. sclerotiorum (MICs = 2-50 μg/ml).{42950}  

     

    Brand:
    Cayman
    SKU:28064 - 100 mg

    Available on backorder

  • 1-Hydroxyphenazine is a phenazine pigment and virulence factor produced by P. aeruginosa.{42947,42948} It increases production of reactive oxygen species (ROS) in RAW 264.7 cells in a concentration-dependent manner.{42948} 1-Hydroxyphenazine (≥1.55 and ≥3.12 μM) increases release of elastase and myeloperoxidase (MPO), respectively, by human neutrophils activated with N-formyl-L-methionyl-L-leucyl-L-phenylalanine (fMLP; Item No. 21495) and cytochalasin B (Item No. 11328).{42947} It reduces ciliary beat frequency in isolated guinea pig tracheal rings, resulting in ciliary dyskinesia by 1 hour when used at concentrations of 10, 50, and 100 μM and ciliary stasis by 5 hours at 50 and 100 μM.{42949} 1-Hydroxyphenazine reduces tracheal mucus velocity in anesthetized guinea pigs when administered as a 100 or 200 ng bolus dose. It is also active against the plant pathogenic fungi F. graminearum, P. grisea, A. solani, F. oxysporium, and S. sclerotiorum (MICs = 2-50 μg/ml).{42950}  

     

    Brand:
    Cayman
    SKU:28064 - 25 mg

    Available on backorder

  • 1-Hydroxyphenazine is a phenazine pigment and virulence factor produced by P. aeruginosa.{42947,42948} It increases production of reactive oxygen species (ROS) in RAW 264.7 cells in a concentration-dependent manner.{42948} 1-Hydroxyphenazine (≥1.55 and ≥3.12 μM) increases release of elastase and myeloperoxidase (MPO), respectively, by human neutrophils activated with N-formyl-L-methionyl-L-leucyl-L-phenylalanine (fMLP; Item No. 21495) and cytochalasin B (Item No. 11328).{42947} It reduces ciliary beat frequency in isolated guinea pig tracheal rings, resulting in ciliary dyskinesia by 1 hour when used at concentrations of 10, 50, and 100 μM and ciliary stasis by 5 hours at 50 and 100 μM.{42949} 1-Hydroxyphenazine reduces tracheal mucus velocity in anesthetized guinea pigs when administered as a 100 or 200 ng bolus dose. It is also active against the plant pathogenic fungi F. graminearum, P. grisea, A. solani, F. oxysporium, and S. sclerotiorum (MICs = 2-50 μg/ml).{42950}  

     

    Brand:
    Cayman
    SKU:28064 - 50 mg

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  • 1-Lauroyl-2-elaidoyl-3-palmitoyl-rac-glycerol is a triacylglycerol that contains lauric acid (Item No. 10006626), elaidic acid (Item No. 90250), and palmitic acid (Item No. 10006627) at the sn-1, sn-2, and sn-3 positions, respectively.  

     

    Brand:
    Cayman
    SKU:26832 - 1 mg

    Available on backorder

  • 1-Lauroyl-2-elaidoyl-3-palmitoyl-rac-glycerol is a triacylglycerol that contains lauric acid (Item No. 10006626), elaidic acid (Item No. 90250), and palmitic acid (Item No. 10006627) at the sn-1, sn-2, and sn-3 positions, respectively.  

     

    Brand:
    Cayman
    SKU:26832 - 10 mg

    Available on backorder

  • 1-Lauroyl-2-elaidoyl-3-palmitoyl-rac-glycerol is a triacylglycerol that contains lauric acid (Item No. 10006626), elaidic acid (Item No. 90250), and palmitic acid (Item No. 10006627) at the sn-1, sn-2, and sn-3 positions, respectively.  

     

    Brand:
    Cayman
    SKU:26832 - 25 mg

    Available on backorder

  • 1-Lauroyl-2-elaidoyl-3-palmitoyl-rac-glycerol is a triacylglycerol that contains lauric acid (Item No. 10006626), elaidic acid (Item No. 90250), and palmitic acid (Item No. 10006627) at the sn-1, sn-2, and sn-3 positions, respectively.  

     

    Brand:
    Cayman
    SKU:26832 - 5 mg

    Available on backorder

  • 1-Lauroyl-2-oleoyl-3-palmitoyl-rac-glycerol is a triacylglycerol that contains lauric acid (Item No. 10006626), oleic acid (Item Nos. 90260 | 24659), and palmitic acid (Item No. 10006627) at the sn-1, sn-2 and sn-3 positions, respectively. It has been found in date seed oil.{49047}  

     

    Brand:
    Cayman
    SKU:28549 - 1 mg

    Available on backorder

  • 1-Lauroyl-2-oleoyl-3-palmitoyl-rac-glycerol is a triacylglycerol that contains lauric acid (Item No. 10006626), oleic acid (Item Nos. 90260 | 24659), and palmitic acid (Item No. 10006627) at the sn-1, sn-2 and sn-3 positions, respectively. It has been found in date seed oil.{49047}  

     

    Brand:
    Cayman
    SKU:28549 - 10 mg

    Available on backorder

  • 1-Lauroyl-2-oleoyl-3-palmitoyl-rac-glycerol is a triacylglycerol that contains lauric acid (Item No. 10006626), oleic acid (Item Nos. 90260 | 24659), and palmitic acid (Item No. 10006627) at the sn-1, sn-2 and sn-3 positions, respectively. It has been found in date seed oil.{49047}  

     

    Brand:
    Cayman
    SKU:28549 - 25 mg

    Available on backorder

  • 1-Lauroyl-2-oleoyl-3-palmitoyl-rac-glycerol is a triacylglycerol that contains lauric acid (Item No. 10006626), oleic acid (Item Nos. 90260 | 24659), and palmitic acid (Item No. 10006627) at the sn-1, sn-2 and sn-3 positions, respectively. It has been found in date seed oil.{49047}  

     

    Brand:
    Cayman
    SKU:28549 - 5 mg

    Available on backorder

  • 1-Lauroyl-2-palmitoyl-rac-glycerol is a diacylglycerol that contains lauric acid (Item No. 10006626) at the sn-1 position and palmitic acid (Item No. 10006627) at the sn-2 position.  

     

    Brand:
    Cayman
    SKU:26882 - 1 mg

    Available on backorder

  • 1-Lauroyl-2-palmitoyl-rac-glycerol is a diacylglycerol that contains lauric acid (Item No. 10006626) at the sn-1 position and palmitic acid (Item No. 10006627) at the sn-2 position.  

     

    Brand:
    Cayman
    SKU:26882 - 10 mg

    Available on backorder

  • 1-Lauroyl-2-palmitoyl-rac-glycerol is a diacylglycerol that contains lauric acid (Item No. 10006626) at the sn-1 position and palmitic acid (Item No. 10006627) at the sn-2 position.  

     

    Brand:
    Cayman
    SKU:26882 - 25 mg

    Available on backorder

  • 1-Lauroyl-2-palmitoyl-rac-glycerol is a diacylglycerol that contains lauric acid (Item No. 10006626) at the sn-1 position and palmitic acid (Item No. 10006627) at the sn-2 position.  

     

    Brand:
    Cayman
    SKU:26882 - 5 mg

    Available on backorder

  • 1-Lauroyl-2-stearoyl-rac-glycerol is a diacylglycerol that contains lauric acid (Item No. 10006626) and stearic acid (Item No. 10011298) at the sn-1 and sn-2 positions, respectively.  

     

    Brand:
    Cayman
    SKU:26881 - 1 mg

    Available on backorder

  • 1-Lauroyl-2-stearoyl-rac-glycerol is a diacylglycerol that contains lauric acid (Item No. 10006626) and stearic acid (Item No. 10011298) at the sn-1 and sn-2 positions, respectively.  

     

    Brand:
    Cayman
    SKU:26881 - 10 mg

    Available on backorder

  • 1-Lauroyl-2-stearoyl-rac-glycerol is a diacylglycerol that contains lauric acid (Item No. 10006626) and stearic acid (Item No. 10011298) at the sn-1 and sn-2 positions, respectively.  

     

    Brand:
    Cayman
    SKU:26881 - 25 mg

    Available on backorder

  • 1-Lauroyl-2-stearoyl-rac-glycerol is a diacylglycerol that contains lauric acid (Item No. 10006626) and stearic acid (Item No. 10011298) at the sn-1 and sn-2 positions, respectively.  

     

    Brand:
    Cayman
    SKU:26881 - 5 mg

    Available on backorder

  • 1-Lauroyl-rac-glycerol is a monoacylglycerol that contains lauric acid (Item No. 10006626) at the sn-1 position. It is active against pneumococci, group A streptococci, β-hemolytic non-group A streptococci, corynebacteria, N. asteroides, micrococci, S. aureus, S. epidermidis, and C. albicans (MICs = 0.045-0.09 μmol/ml).{53096} It is also active against a panel of 16 fungi when used at a concentration of 0.1% in growth media.{53097} Dietary administration of 1-lauroyl-rac-glycerol (2% w/w) reduces S. mutans colony forming units (CFUs) on tooth surfaces and severity of sucrose-induced dental caries in rats.{53098}  

     

    Brand:
    Cayman
    SKU:28170 - 1 g

    Available on backorder

  • 1-Lauroyl-rac-glycerol is a monoacylglycerol that contains lauric acid (Item No. 10006626) at the sn-1 position. It is active against pneumococci, group A streptococci, β-hemolytic non-group A streptococci, corynebacteria, N. asteroides, micrococci, S. aureus, S. epidermidis, and C. albicans (MICs = 0.045-0.09 μmol/ml).{53096} It is also active against a panel of 16 fungi when used at a concentration of 0.1% in growth media.{53097} Dietary administration of 1-lauroyl-rac-glycerol (2% w/w) reduces S. mutans colony forming units (CFUs) on tooth surfaces and severity of sucrose-induced dental caries in rats.{53098}  

     

    Brand:
    Cayman
    SKU:28170 - 500 mg

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  • Platelet-activating factor (PAF) is a biologically active phospholipid synthesized by a variety of stimulated cells that acts as a mediator of platelet aggregation, inflammation, and allergy.{939,11753} PAF is converted to the biologically inactive lyso-PAF by the enzyme PAF acetylhydrolase (PAF-AH). Recently, plasma PAF-AH has been linked to atherosclerosis and may be a positive risk factor for coronary heart disease in humans.{11455} 1-Linoleoyl glycerol (1-LG) is a fatty acid glycerol that has been isolated from S. chinensis roots. It inhibits PAF-AH with an IC50 of 45 µM.{14173} 1-LG has potential application in cholesterol lowering and antiatherogenic activity.  

     

    Brand:
    Cayman
    SKU:10008869 - 1 mg

    Available on backorder

  • Platelet-activating factor (PAF) is a biologically active phospholipid synthesized by a variety of stimulated cells that acts as a mediator of platelet aggregation, inflammation, and allergy.{939,11753} PAF is converted to the biologically inactive lyso-PAF by the enzyme PAF acetylhydrolase (PAF-AH). Recently, plasma PAF-AH has been linked to atherosclerosis and may be a positive risk factor for coronary heart disease in humans.{11455} 1-Linoleoyl glycerol (1-LG) is a fatty acid glycerol that has been isolated from S. chinensis roots. It inhibits PAF-AH with an IC50 of 45 µM.{14173} 1-LG has potential application in cholesterol lowering and antiatherogenic activity.  

     

    Brand:
    Cayman
    SKU:10008869 - 10 mg

    Available on backorder