Chemicals
Showing 15751–15900 of 41137 results
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Curcumin is the major yellow pigment in turmeric and curry and has antioxidant, anti-inflammatory, and antitumor activities.{1421,42430,1420,1419} It inhibits nitric oxide (NO) production (IC50 = 6 μM) and reduces inducible nitric oxide synthase (iNOS) activity in LPS-stimulated RAW 264.7 cells.{1421} Curcumin inhibits release of histamine and the inflammatory cytokines TNF-α, IL-1β, IL-6, and IL-8 from HMC-1 mast cells.{42430} In vivo, curcumin decreases serum levels of histamine and TNF-α, inhibits histopathological changes of nasal mucosa, and decreases the number of sneezes and nasal rubbing in a mouse model of ovalbumin-induced rhinitis. Curcumin (100 or 200 mg/kg) prevents ovalbumin-induced accumulation of 3-nitrotyrosine (3-NT), a marker of oxidative stress, in mouse heart. Topical administration of curcumin (1-10 μmol) reduces the number of tumors induced by phorbol 12-myristate 13-acetate (TPA; Item No. 10008014) in mouse skin.{1420} Dietary administration of curcumin reduces the number of tongue neoplasms and preneoplastic lesions induced by 4-nitroquinoline 1-oxide (4-NQO) in rats.{1419}
Brand:CaymanSKU:81025 - 100 gAvailable on backorder
Curcumin is the major yellow pigment in turmeric and curry and has antioxidant, anti-inflammatory, and antitumor activities.{1421,42430,1420,1419} It inhibits nitric oxide (NO) production (IC50 = 6 μM) and reduces inducible nitric oxide synthase (iNOS) activity in LPS-stimulated RAW 264.7 cells.{1421} Curcumin inhibits release of histamine and the inflammatory cytokines TNF-α, IL-1β, IL-6, and IL-8 from HMC-1 mast cells.{42430} In vivo, curcumin decreases serum levels of histamine and TNF-α, inhibits histopathological changes of nasal mucosa, and decreases the number of sneezes and nasal rubbing in a mouse model of ovalbumin-induced rhinitis. Curcumin (100 or 200 mg/kg) prevents ovalbumin-induced accumulation of 3-nitrotyrosine (3-NT), a marker of oxidative stress, in mouse heart. Topical administration of curcumin (1-10 μmol) reduces the number of tumors induced by phorbol 12-myristate 13-acetate (TPA; Item No. 10008014) in mouse skin.{1420} Dietary administration of curcumin reduces the number of tongue neoplasms and preneoplastic lesions induced by 4-nitroquinoline 1-oxide (4-NQO) in rats.{1419}
Brand:CaymanSKU:81025 - 5 gAvailable on backorder
Curcumin is the major yellow pigment in turmeric and curry and has antioxidant, anti-inflammatory, and antitumor activities.{1421,42430,1420,1419} It inhibits nitric oxide (NO) production (IC50 = 6 μM) and reduces inducible nitric oxide synthase (iNOS) activity in LPS-stimulated RAW 264.7 cells.{1421} Curcumin inhibits release of histamine and the inflammatory cytokines TNF-α, IL-1β, IL-6, and IL-8 from HMC-1 mast cells.{42430} In vivo, curcumin decreases serum levels of histamine and TNF-α, inhibits histopathological changes of nasal mucosa, and decreases the number of sneezes and nasal rubbing in a mouse model of ovalbumin-induced rhinitis. Curcumin (100 or 200 mg/kg) prevents ovalbumin-induced accumulation of 3-nitrotyrosine (3-NT), a marker of oxidative stress, in mouse heart. Topical administration of curcumin (1-10 μmol) reduces the number of tumors induced by phorbol 12-myristate 13-acetate (TPA; Item No. 10008014) in mouse skin.{1420} Dietary administration of curcumin reduces the number of tongue neoplasms and preneoplastic lesions induced by 4-nitroquinoline 1-oxide (4-NQO) in rats.{1419}
Brand:CaymanSKU:81025 - 50 gAvailable on backorder
Curcumin is the major yellow pigment in turmeric and curry and has antioxidant, anti-inflammatory, and antitumor activities.{1421,42430,1420,1419} It inhibits nitric oxide (NO) production (IC50 = 6 μM) and reduces inducible nitric oxide synthase (iNOS) activity in LPS-stimulated RAW 264.7 cells.{1421} Curcumin inhibits release of histamine and the inflammatory cytokines TNF-α, IL-1β, IL-6, and IL-8 from HMC-1 mast cells.{42430} In vivo, curcumin decreases serum levels of histamine and TNF-α, inhibits histopathological changes of nasal mucosa, and decreases the number of sneezes and nasal rubbing in a mouse model of ovalbumin-induced rhinitis. Curcumin (100 or 200 mg/kg) prevents ovalbumin-induced accumulation of 3-nitrotyrosine (3-NT), a marker of oxidative stress, in mouse heart. Topical administration of curcumin (1-10 μmol) reduces the number of tumors induced by phorbol 12-myristate 13-acetate (TPA; Item No. 10008014) in mouse skin.{1420} Dietary administration of curcumin reduces the number of tongue neoplasms and preneoplastic lesions induced by 4-nitroquinoline 1-oxide (4-NQO) in rats.{1419}
Brand:CaymanSKU:81025.1 - 10 gAvailable on backorder
Curcumin is the major yellow pigment in turmeric and curry and has antioxidant, anti-inflammatory, and antitumor activities.{1421,42430,1420,1419} It inhibits nitric oxide (NO) production (IC50 = 6 μM) and reduces inducible nitric oxide synthase (iNOS) activity in LPS-stimulated RAW 264.7 cells.{1421} Curcumin inhibits release of histamine and the inflammatory cytokines TNF-α, IL-1β, IL-6, and IL-8 from HMC-1 mast cells.{42430} In vivo, curcumin decreases serum levels of histamine and TNF-α, inhibits histopathological changes of nasal mucosa, and decreases the number of sneezes and nasal rubbing in a mouse model of ovalbumin-induced rhinitis. Curcumin (100 or 200 mg/kg) prevents ovalbumin-induced accumulation of 3-nitrotyrosine (3-NT), a marker of oxidative stress, in mouse heart. Topical administration of curcumin (1-10 μmol) reduces the number of tumors induced by phorbol 12-myristate 13-acetate (TPA; Item No. 10008014) in mouse skin.{1420} Dietary administration of curcumin reduces the number of tongue neoplasms and preneoplastic lesions induced by 4-nitroquinoline 1-oxide (4-NQO) in rats.{1419}
Brand:CaymanSKU:81025.1 - 100 gAvailable on backorder
Curcumin is the major yellow pigment in turmeric and curry and has antioxidant, anti-inflammatory, and antitumor activities.{1421,42430,1420,1419} It inhibits nitric oxide (NO) production (IC50 = 6 μM) and reduces inducible nitric oxide synthase (iNOS) activity in LPS-stimulated RAW 264.7 cells.{1421} Curcumin inhibits release of histamine and the inflammatory cytokines TNF-α, IL-1β, IL-6, and IL-8 from HMC-1 mast cells.{42430} In vivo, curcumin decreases serum levels of histamine and TNF-α, inhibits histopathological changes of nasal mucosa, and decreases the number of sneezes and nasal rubbing in a mouse model of ovalbumin-induced rhinitis. Curcumin (100 or 200 mg/kg) prevents ovalbumin-induced accumulation of 3-nitrotyrosine (3-NT), a marker of oxidative stress, in mouse heart. Topical administration of curcumin (1-10 μmol) reduces the number of tumors induced by phorbol 12-myristate 13-acetate (TPA; Item No. 10008014) in mouse skin.{1420} Dietary administration of curcumin reduces the number of tongue neoplasms and preneoplastic lesions induced by 4-nitroquinoline 1-oxide (4-NQO) in rats.{1419}
Brand:CaymanSKU:81025.1 - 5 gAvailable on backorder
Curcumin is the major yellow pigment in turmeric and curry and has antioxidant, anti-inflammatory, and antitumor activities.{1421,42430,1420,1419} It inhibits nitric oxide (NO) production (IC50 = 6 μM) and reduces inducible nitric oxide synthase (iNOS) activity in LPS-stimulated RAW 264.7 cells.{1421} Curcumin inhibits release of histamine and the inflammatory cytokines TNF-α, IL-1β, IL-6, and IL-8 from HMC-1 mast cells.{42430} In vivo, curcumin decreases serum levels of histamine and TNF-α, inhibits histopathological changes of nasal mucosa, and decreases the number of sneezes and nasal rubbing in a mouse model of ovalbumin-induced rhinitis. Curcumin (100 or 200 mg/kg) prevents ovalbumin-induced accumulation of 3-nitrotyrosine (3-NT), a marker of oxidative stress, in mouse heart. Topical administration of curcumin (1-10 μmol) reduces the number of tumors induced by phorbol 12-myristate 13-acetate (TPA; Item No. 10008014) in mouse skin.{1420} Dietary administration of curcumin reduces the number of tongue neoplasms and preneoplastic lesions induced by 4-nitroquinoline 1-oxide (4-NQO) in rats.{1419}
Brand:CaymanSKU:81025.1 - 50 gAvailable on backorder
Curcumin-d6 is intended for use as an internal standard for the quantification of curcumin (Item Nos. 81025 | 81025.1) by GC- or LC-MS. Curcumin is the major yellow pigment in turmeric and curry and has antioxidant, anti-inflammatory, and antitumor activities.{1421,42430,1420,1419} It inhibits nitric oxide (NO) production (IC50 = 6 μM) and reduces inducible nitric oxide synthase (iNOS) activity in LPS-stimulated RAW 264.7 cells.{1421} Curcumin inhibits release of histamine and the inflammatory cytokines TNF-α, IL-1β, IL-6, and IL-8 from HMC-1 mast cells.{42430} In vivo, curcumin decreases serum levels of histamine and TNF-α, inhibits histopathological changes of nasal mucosa, and decreases the number of sneezes and nasal rubbing in a mouse model of ovalbumin-induced rhinitis. Curcumin (100 or 200 mg/kg) prevents ovalbumin-induced accumulation of 3-nitrotyrosine (3-NT), a marker of oxidative stress, in mouse heart. Topical administration of curcumin (1-10 μmol) reduces the number of tumors induced by phorbol 12-myristate 13-acetate (TPA; Item No. 10008014) in mouse skin.{1420} Dietary administration of curcumin reduces the number of tongue neoplasms and preneoplastic lesions induced by 4-nitroquinoline 1-oxide (4-NQO) in rats.{1419}
Brand:CaymanSKU:25438 - 1 mgAvailable on backorder
Curcumin-d6 is intended for use as an internal standard for the quantification of curcumin (Item Nos. 81025 | 81025.1) by GC- or LC-MS. Curcumin is the major yellow pigment in turmeric and curry and has antioxidant, anti-inflammatory, and antitumor activities.{1421,42430,1420,1419} It inhibits nitric oxide (NO) production (IC50 = 6 μM) and reduces inducible nitric oxide synthase (iNOS) activity in LPS-stimulated RAW 264.7 cells.{1421} Curcumin inhibits release of histamine and the inflammatory cytokines TNF-α, IL-1β, IL-6, and IL-8 from HMC-1 mast cells.{42430} In vivo, curcumin decreases serum levels of histamine and TNF-α, inhibits histopathological changes of nasal mucosa, and decreases the number of sneezes and nasal rubbing in a mouse model of ovalbumin-induced rhinitis. Curcumin (100 or 200 mg/kg) prevents ovalbumin-induced accumulation of 3-nitrotyrosine (3-NT), a marker of oxidative stress, in mouse heart. Topical administration of curcumin (1-10 μmol) reduces the number of tumors induced by phorbol 12-myristate 13-acetate (TPA; Item No. 10008014) in mouse skin.{1420} Dietary administration of curcumin reduces the number of tongue neoplasms and preneoplastic lesions induced by 4-nitroquinoline 1-oxide (4-NQO) in rats.{1419}
Brand:CaymanSKU:25438 - 5 mgAvailable on backorder
Curcumin-d6 is intended for use as an internal standard for the quantification of curcumin (Item Nos. 81025 | 81025.1) by GC- or LC-MS. Curcumin is the major yellow pigment in turmeric and curry and has antioxidant, anti-inflammatory, and antitumor activities.{1421,42430,1420,1419} It inhibits nitric oxide (NO) production (IC50 = 6 μM) and reduces inducible nitric oxide synthase (iNOS) activity in LPS-stimulated RAW 264.7 cells.{1421} Curcumin inhibits release of histamine and the inflammatory cytokines TNF-α, IL-1β, IL-6, and IL-8 from HMC-1 mast cells.{42430} In vivo, curcumin decreases serum levels of histamine and TNF-α, inhibits histopathological changes of nasal mucosa, and decreases the number of sneezes and nasal rubbing in a mouse model of ovalbumin-induced rhinitis. Curcumin (100 or 200 mg/kg) prevents ovalbumin-induced accumulation of 3-nitrotyrosine (3-NT), a marker of oxidative stress, in mouse heart. Topical administration of curcumin (1-10 μmol) reduces the number of tumors induced by phorbol 12-myristate 13-acetate (TPA; Item No. 10008014) in mouse skin.{1420} Dietary administration of curcumin reduces the number of tongue neoplasms and preneoplastic lesions induced by 4-nitroquinoline 1-oxide (4-NQO) in rats.{1419}
Brand:CaymanSKU:25438 - 500 µgAvailable on backorder
Curcumol is a sesquiterpene alcohol that has been found in Curcumae oil and has diverse biological activities.{48354,48355,48356,48357} It is a positive allosteric modulator (PAM) of GABAA receptors that potentiates GABA-induced currents in the presence of the benzodiazepine GABA agonist diazepam, but not the GABAA PAM (–)-menthol, in mouse hippocampal neurons.{48354} Curcumol (1-200 μg/ml) reduces activation of proinflammatory NF-κB and profibrotic TGF-β1/SMAD signaling pathways in RAW 264.7 cells stimulated with cigarette smoke extract.{48355} It inhibits proliferation of and induces apoptosis in LoVo and SW480 colorectal cancer cells in a concentration-dependent manner.{48356} In vivo, curcumol (20-80 mg/kg) reduces tumor volume in a LoVo mouse xenograft model. Curcumol also increases the rate of wound closure in rats with diabetes induced by streptozotocin (Item No. 13104).{48357}
Brand:CaymanSKU:26849 - 10 mgAvailable on backorder
Curcumol is a sesquiterpene alcohol that has been found in Curcumae oil and has diverse biological activities.{48354,48355,48356,48357} It is a positive allosteric modulator (PAM) of GABAA receptors that potentiates GABA-induced currents in the presence of the benzodiazepine GABA agonist diazepam, but not the GABAA PAM (–)-menthol, in mouse hippocampal neurons.{48354} Curcumol (1-200 μg/ml) reduces activation of proinflammatory NF-κB and profibrotic TGF-β1/SMAD signaling pathways in RAW 264.7 cells stimulated with cigarette smoke extract.{48355} It inhibits proliferation of and induces apoptosis in LoVo and SW480 colorectal cancer cells in a concentration-dependent manner.{48356} In vivo, curcumol (20-80 mg/kg) reduces tumor volume in a LoVo mouse xenograft model. Curcumol also increases the rate of wound closure in rats with diabetes induced by streptozotocin (Item No. 13104).{48357}
Brand:CaymanSKU:26849 - 100 mgAvailable on backorder
Curcumol is a sesquiterpene alcohol that has been found in Curcumae oil and has diverse biological activities.{48354,48355,48356,48357} It is a positive allosteric modulator (PAM) of GABAA receptors that potentiates GABA-induced currents in the presence of the benzodiazepine GABA agonist diazepam, but not the GABAA PAM (–)-menthol, in mouse hippocampal neurons.{48354} Curcumol (1-200 μg/ml) reduces activation of proinflammatory NF-κB and profibrotic TGF-β1/SMAD signaling pathways in RAW 264.7 cells stimulated with cigarette smoke extract.{48355} It inhibits proliferation of and induces apoptosis in LoVo and SW480 colorectal cancer cells in a concentration-dependent manner.{48356} In vivo, curcumol (20-80 mg/kg) reduces tumor volume in a LoVo mouse xenograft model. Curcumol also increases the rate of wound closure in rats with diabetes induced by streptozotocin (Item No. 13104).{48357}
Brand:CaymanSKU:26849 - 25 mgAvailable on backorder
Curcumol is a sesquiterpene alcohol that has been found in Curcumae oil and has diverse biological activities.{48354,48355,48356,48357} It is a positive allosteric modulator (PAM) of GABAA receptors that potentiates GABA-induced currents in the presence of the benzodiazepine GABA agonist diazepam, but not the GABAA PAM (–)-menthol, in mouse hippocampal neurons.{48354} Curcumol (1-200 μg/ml) reduces activation of proinflammatory NF-κB and profibrotic TGF-β1/SMAD signaling pathways in RAW 264.7 cells stimulated with cigarette smoke extract.{48355} It inhibits proliferation of and induces apoptosis in LoVo and SW480 colorectal cancer cells in a concentration-dependent manner.{48356} In vivo, curcumol (20-80 mg/kg) reduces tumor volume in a LoVo mouse xenograft model. Curcumol also increases the rate of wound closure in rats with diabetes induced by streptozotocin (Item No. 13104).{48357}
Brand:CaymanSKU:26849 - 50 mgAvailable on backorder
Curdione is a sesquiterpene that has been found in C. wenyujin and has diverse biological activities. It reduces the cytopathic effect of influenza A in MDCK cells (IC50 = 28.32 μM).{52521} Curdione (100 μM) inhibits thrombin-induced aggregation, AMP-activated protein kinase (AMPK) and integrin αIIbβ3 phosphorylation, and increases in talin and vinculin levels in washed platelets.{52522} It inhibits prostaglandin E2 (PGE2; Item No. 14010) production in LPS-stimulated RAW 264.7 macrophages (IC50 = 1.12 μM).{52523}
Brand:CaymanSKU:30365 - 1 mgAvailable on backorder
Curdione is a sesquiterpene that has been found in C. wenyujin and has diverse biological activities. It reduces the cytopathic effect of influenza A in MDCK cells (IC50 = 28.32 μM).{52521} Curdione (100 μM) inhibits thrombin-induced aggregation, AMP-activated protein kinase (AMPK) and integrin αIIbβ3 phosphorylation, and increases in talin and vinculin levels in washed platelets.{52522} It inhibits prostaglandin E2 (PGE2; Item No. 14010) production in LPS-stimulated RAW 264.7 macrophages (IC50 = 1.12 μM).{52523}
Brand:CaymanSKU:30365 - 5 mgAvailable on backorder
Curdione is a sesquiterpene that has been found in C. wenyujin and has diverse biological activities. It reduces the cytopathic effect of influenza A in MDCK cells (IC50 = 28.32 μM).{52521} Curdione (100 μM) inhibits thrombin-induced aggregation, AMP-activated protein kinase (AMPK) and integrin αIIbβ3 phosphorylation, and increases in talin and vinculin levels in washed platelets.{52522} It inhibits prostaglandin E2 (PGE2; Item No. 14010) production in LPS-stimulated RAW 264.7 macrophages (IC50 = 1.12 μM).{52523}
Brand:CaymanSKU:30365 - 500 µgAvailable on backorder
Curvularin is a natural fungal macrolactone that has cytotoxic activity against select cancer cell lines.{34313,34316} It inhibits cytokine-induced expression of induced nitric oxide synthase (iNOS; IC50 = 9.5 µM) in vitro and reduces proinflammatory gene expression in a mouse model of rheumatoid arthritis.{32339,34321} Curvularin also blocks TGF-β signaling in HepG2 and MDA-MB-231 cells.{34314}
Brand:CaymanSKU:21758 -Out of stock
Curvularin is a natural fungal macrolactone that has cytotoxic activity against select cancer cell lines.{34313,34316} It inhibits cytokine-induced expression of induced nitric oxide synthase (iNOS; IC50 = 9.5 µM) in vitro and reduces proinflammatory gene expression in a mouse model of rheumatoid arthritis.{32339,34321} Curvularin also blocks TGF-β signaling in HepG2 and MDA-MB-231 cells.{34314}
Brand:CaymanSKU:21758 -Out of stock
Curvulin is a phytotoxin first isolated from several species of the mold Curvularia. It is reported to inhibit microtubule assembly and has also been shown to inhibit iNOS expression.{32338,32339}
Brand:CaymanSKU:19609 -Available on backorder
Curvulin is a phytotoxin first isolated from several species of the mold Curvularia. It is reported to inhibit microtubule assembly and has also been shown to inhibit iNOS expression.{32338,32339}
Brand:CaymanSKU:19609 -Available on backorder
The Survival of Motor Neurons (SMN) protein participates in RNA splicing. Decreases in SMN, typically a consequence of defects in the smn1 gene, result in the death of motor neurons and lead to the neurodegenerative disease, spinal muscular atrophy (SMA).{22324} Cuspin-1 is a small molecule upregulator of SMN that has been shown in vitro to increase levels of SMN in SMA patient fibroblasts by 50% at 18 µM.{30105} Its mechanism of action is thought to involve increased phosphorylation of ERK to initiate Ras-Raf-MEK signaling, which results in an increased rate of SMN translation.{30105}
Brand:CaymanSKU:-Available on backorder
The Survival of Motor Neurons (SMN) protein participates in RNA splicing. Decreases in SMN, typically a consequence of defects in the smn1 gene, result in the death of motor neurons and lead to the neurodegenerative disease, spinal muscular atrophy (SMA).{22324} Cuspin-1 is a small molecule upregulator of SMN that has been shown in vitro to increase levels of SMN in SMA patient fibroblasts by 50% at 18 µM.{30105} Its mechanism of action is thought to involve increased phosphorylation of ERK to initiate Ras-Raf-MEK signaling, which results in an increased rate of SMN translation.{30105}
Brand:CaymanSKU:-Available on backorder
The Survival of Motor Neurons (SMN) protein participates in RNA splicing. Decreases in SMN, typically a consequence of defects in the smn1 gene, result in the death of motor neurons and lead to the neurodegenerative disease, spinal muscular atrophy (SMA).{22324} Cuspin-1 is a small molecule upregulator of SMN that has been shown in vitro to increase levels of SMN in SMA patient fibroblasts by 50% at 18 µM.{30105} Its mechanism of action is thought to involve increased phosphorylation of ERK to initiate Ras-Raf-MEK signaling, which results in an increased rate of SMN translation.{30105}
Brand:CaymanSKU:-Available on backorder
The Survival of Motor Neurons (SMN) protein participates in RNA splicing. Decreases in SMN, typically a consequence of defects in the smn1 gene, result in the death of motor neurons and lead to the neurodegenerative disease, spinal muscular atrophy (SMA).{22324} Cuspin-1 is a small molecule upregulator of SMN that has been shown in vitro to increase levels of SMN in SMA patient fibroblasts by 50% at 18 µM.{30105} Its mechanism of action is thought to involve increased phosphorylation of ERK to initiate Ras-Raf-MEK signaling, which results in an increased rate of SMN translation.{30105}
Brand:CaymanSKU:-Available on backorder
CV-6209 is a potent antagonist of the platelet-activating factor (PAF) receptor, inhibiting aggregation of rabbit and human platelets induced by PAF with IC50 values of 75 and 170 nM, respectively.{27971} It has little action on platelet aggregation induced by arachidonic acid, ADP, or collagen.{27971} CV-6209 is bioavailable, as it prevents PAF-induced hypotension in rats, while not blocking hypotension triggered by arachidonic acid (Item No. 90010), histamine, bradykinin (Item No. 15539), or isoproterenol (Item No. 15592).{27971} CV-6209 is used to study the role of PAF receptor signaling in vitro and in vivo.{27973,27972}
Brand:CaymanSKU:- CV-6209 is a potent antagonist of the platelet-activating factor (PAF) receptor, inhibiting aggregation of rabbit and human platelets induced by PAF with IC50 values of 75 and 170 nM, respectively.{27971} It has little action on platelet aggregation induced by arachidonic acid, ADP, or collagen.{27971} CV-6209 is bioavailable, as it prevents PAF-induced hypotension in rats, while not blocking hypotension triggered by arachidonic acid (Item No. 90010), histamine, bradykinin (Item No. 15539), or isoproterenol (Item No. 15592).{27971} CV-6209 is used to study the role of PAF receptor signaling in vitro and in vivo.{27973,27972}
Brand:CaymanSKU:- CV-6209 is a potent antagonist of the platelet-activating factor (PAF) receptor, inhibiting aggregation of rabbit and human platelets induced by PAF with IC50 values of 75 and 170 nM, respectively.{27971} It has little action on platelet aggregation induced by arachidonic acid, ADP, or collagen.{27971} CV-6209 is bioavailable, as it prevents PAF-induced hypotension in rats, while not blocking hypotension triggered by arachidonic acid (Item No. 90010), histamine, bradykinin (Item No. 15539), or isoproterenol (Item No. 15592).{27971} CV-6209 is used to study the role of PAF receptor signaling in vitro and in vivo.{27973,27972}
Brand:CaymanSKU:-
Aldehyde dehydrogenase 2 (ALDH2) is a mitochondrial enzyme involved in the major oxidative pathway of alcohol metabolism. CVT-10216 is a reversible inhibitor of ALDH2 (IC50 = 29 nM) that demonstrates >40-fold selectivity for ALDH2 over the cytosolic isoform, ALDH1.{30040} CVT-10216 has been reported to reduce excessive alcohol drinking in alcohol-preferring rats and to prevent self-administration of alcohol in Long-Evans rats.{30040} This compound has also been shown to produce anxiolytic effects in four different rodent models, including a model of repeated alcohol withdrawal-induced anxiety.{30040} The efficacy of CVT-10216 has also been examined in rodent models of drug addiction or binge eating of high-fat or high-sugar diets.{30039}
Brand:CaymanSKU:-Available on backorder
Aldehyde dehydrogenase 2 (ALDH2) is a mitochondrial enzyme involved in the major oxidative pathway of alcohol metabolism. CVT-10216 is a reversible inhibitor of ALDH2 (IC50 = 29 nM) that demonstrates >40-fold selectivity for ALDH2 over the cytosolic isoform, ALDH1.{30040} CVT-10216 has been reported to reduce excessive alcohol drinking in alcohol-preferring rats and to prevent self-administration of alcohol in Long-Evans rats.{30040} This compound has also been shown to produce anxiolytic effects in four different rodent models, including a model of repeated alcohol withdrawal-induced anxiety.{30040} The efficacy of CVT-10216 has also been examined in rodent models of drug addiction or binge eating of high-fat or high-sugar diets.{30039}
Brand:CaymanSKU:-Available on backorder
Aldehyde dehydrogenase 2 (ALDH2) is a mitochondrial enzyme involved in the major oxidative pathway of alcohol metabolism. CVT-10216 is a reversible inhibitor of ALDH2 (IC50 = 29 nM) that demonstrates >40-fold selectivity for ALDH2 over the cytosolic isoform, ALDH1.{30040} CVT-10216 has been reported to reduce excessive alcohol drinking in alcohol-preferring rats and to prevent self-administration of alcohol in Long-Evans rats.{30040} This compound has also been shown to produce anxiolytic effects in four different rodent models, including a model of repeated alcohol withdrawal-induced anxiety.{30040} The efficacy of CVT-10216 has also been examined in rodent models of drug addiction or binge eating of high-fat or high-sugar diets.{30039}
Brand:CaymanSKU:-Available on backorder
Aldehyde dehydrogenase 2 (ALDH2) is a mitochondrial enzyme involved in the major oxidative pathway of alcohol metabolism. CVT-10216 is a reversible inhibitor of ALDH2 (IC50 = 29 nM) that demonstrates >40-fold selectivity for ALDH2 over the cytosolic isoform, ALDH1.{30040} CVT-10216 has been reported to reduce excessive alcohol drinking in alcohol-preferring rats and to prevent self-administration of alcohol in Long-Evans rats.{30040} This compound has also been shown to produce anxiolytic effects in four different rodent models, including a model of repeated alcohol withdrawal-induced anxiety.{30040} The efficacy of CVT-10216 has also been examined in rodent models of drug addiction or binge eating of high-fat or high-sugar diets.{30039}
Brand:CaymanSKU:-Available on backorder
CVT-12012 is an orally bioavailable inhibitor of stearoyl-CoA desaturase (SCD; IC50 = 6.1 nM in HepG2 cells).{46204} It dose-dependently reduces levels of the SCD desaturation products palmitoleic acid (Item No. 10009871) and vaccenic acid in the plasma and liver of rats fed a high-sucrose diet. CVT-12012 (20 mg/kg) also reduces hepatic triglyceride levels in sucrose-fed rats.
Brand:CaymanSKU:27156 - 1 mgAvailable on backorder
CVT-12012 is an orally bioavailable inhibitor of stearoyl-CoA desaturase (SCD; IC50 = 6.1 nM in HepG2 cells).{46204} It dose-dependently reduces levels of the SCD desaturation products palmitoleic acid (Item No. 10009871) and vaccenic acid in the plasma and liver of rats fed a high-sucrose diet. CVT-12012 (20 mg/kg) also reduces hepatic triglyceride levels in sucrose-fed rats.
Brand:CaymanSKU:27156 - 10 mgAvailable on backorder
CVT-12012 is an orally bioavailable inhibitor of stearoyl-CoA desaturase (SCD; IC50 = 6.1 nM in HepG2 cells).{46204} It dose-dependently reduces levels of the SCD desaturation products palmitoleic acid (Item No. 10009871) and vaccenic acid in the plasma and liver of rats fed a high-sucrose diet. CVT-12012 (20 mg/kg) also reduces hepatic triglyceride levels in sucrose-fed rats.
Brand:CaymanSKU:27156 - 25 mgAvailable on backorder
CVT-12012 is an orally bioavailable inhibitor of stearoyl-CoA desaturase (SCD; IC50 = 6.1 nM in HepG2 cells).{46204} It dose-dependently reduces levels of the SCD desaturation products palmitoleic acid (Item No. 10009871) and vaccenic acid in the plasma and liver of rats fed a high-sucrose diet. CVT-12012 (20 mg/kg) also reduces hepatic triglyceride levels in sucrose-fed rats.
Brand:CaymanSKU:27156 - 5 mgAvailable on backorder
CVT-313 is a competitive inhibitor of cyclin-dependent kinase 2 (Cdk2; IC50 = 0.5 µM in vitro).{32889} It displays 8.5- and 430-fold selectivity for Cdk2 over Cdk1 and Cdk4, respectively, and has no effect on other unrelated ATP-dependent serine/threonine kinases.{32889} CVT-313 induces cell cycle arrest at the G1/S boundary.{32889} CVT-313 is often used as a selective Cdk2 inhibitor, although at some concentrations and in some cells it may also inhibit Cdk1.{32889,32888,32890,23163}
Brand:CaymanSKU:21044 -Out of stock
CVT-313 is a competitive inhibitor of cyclin-dependent kinase 2 (Cdk2; IC50 = 0.5 µM in vitro).{32889} It displays 8.5- and 430-fold selectivity for Cdk2 over Cdk1 and Cdk4, respectively, and has no effect on other unrelated ATP-dependent serine/threonine kinases.{32889} CVT-313 induces cell cycle arrest at the G1/S boundary.{32889} CVT-313 is often used as a selective Cdk2 inhibitor, although at some concentrations and in some cells it may also inhibit Cdk1.{32889,32888,32890,23163}
Brand:CaymanSKU:21044 -Out of stock
CVT-313 is a competitive inhibitor of cyclin-dependent kinase 2 (Cdk2; IC50 = 0.5 µM in vitro).{32889} It displays 8.5- and 430-fold selectivity for Cdk2 over Cdk1 and Cdk4, respectively, and has no effect on other unrelated ATP-dependent serine/threonine kinases.{32889} CVT-313 induces cell cycle arrest at the G1/S boundary.{32889} CVT-313 is often used as a selective Cdk2 inhibitor, although at some concentrations and in some cells it may also inhibit Cdk1.{32889,32888,32890,23163}
Brand:CaymanSKU:21044 -Out of stock
CW069 is an allosteric inhibitor of KIFC/HSET (IC50 = 75 µM), a microtubule motor protein involved in bipolar spindle assembly and centrosome clustering.{47086} It increases the number of multipolar spindles in N1E-115 mouse neuroblastoma cells with supernumerary centrosomes when used at concentrations of 100 and 200 µM, without affecting the morphology of mitotic spindles in normal human dermal fibroblast (NHDF) cells. CW069 inhibits proliferation of N1E-115, but not NHDF, cells (IC50s = 86 and 181 µM, respectively).
Brand:CaymanSKU:22936 - 1 mgAvailable on backorder
CW069 is an allosteric inhibitor of KIFC/HSET (IC50 = 75 µM), a microtubule motor protein involved in bipolar spindle assembly and centrosome clustering.{47086} It increases the number of multipolar spindles in N1E-115 mouse neuroblastoma cells with supernumerary centrosomes when used at concentrations of 100 and 200 µM, without affecting the morphology of mitotic spindles in normal human dermal fibroblast (NHDF) cells. CW069 inhibits proliferation of N1E-115, but not NHDF, cells (IC50s = 86 and 181 µM, respectively).
Brand:CaymanSKU:22936 - 10 mgAvailable on backorder
CW069 is an allosteric inhibitor of KIFC/HSET (IC50 = 75 µM), a microtubule motor protein involved in bipolar spindle assembly and centrosome clustering.{47086} It increases the number of multipolar spindles in N1E-115 mouse neuroblastoma cells with supernumerary centrosomes when used at concentrations of 100 and 200 µM, without affecting the morphology of mitotic spindles in normal human dermal fibroblast (NHDF) cells. CW069 inhibits proliferation of N1E-115, but not NHDF, cells (IC50s = 86 and 181 µM, respectively).
Brand:CaymanSKU:22936 - 5 mgAvailable on backorder
CWHM12 is an analog of RGD peptide (Item No. 14501), a tripeptide that inhibits integrin-ligand interactions in studies related to cell adhesion, migration, growth, and differentiation.{5588} CWHM12 selectively inhibits αv integrins (IC50s = 1.8, 0.8, 61, 1.5, and 0.2 nM for αvβ1, αvβ3, αvβ5, αvβ6, and αvβ8, respectively) over αIIbβ3, α2β1, and α10β1.{33437} CWHM 12 attenuates liver, lung, and pancreatic fibrosis in mice treated with CCl4 or cerulein.{33437,33439}
Brand:CaymanSKU:-Available on backorder
CWHM12 is an analog of RGD peptide (Item No. 14501), a tripeptide that inhibits integrin-ligand interactions in studies related to cell adhesion, migration, growth, and differentiation.{5588} CWHM12 selectively inhibits αv integrins (IC50s = 1.8, 0.8, 61, 1.5, and 0.2 nM for αvβ1, αvβ3, αvβ5, αvβ6, and αvβ8, respectively) over αIIbβ3, α2β1, and α10β1.{33437} CWHM 12 attenuates liver, lung, and pancreatic fibrosis in mice treated with CCl4 or cerulein.{33437,33439}
Brand:CaymanSKU:-Available on backorder
CWHM12 is an analog of RGD peptide (Item No. 14501), a tripeptide that inhibits integrin-ligand interactions in studies related to cell adhesion, migration, growth, and differentiation.{5588} CWHM12 selectively inhibits αv integrins (IC50s = 1.8, 0.8, 61, 1.5, and 0.2 nM for αvβ1, αvβ3, αvβ5, αvβ6, and αvβ8, respectively) over αIIbβ3, α2β1, and α10β1.{33437} CWHM 12 attenuates liver, lung, and pancreatic fibrosis in mice treated with CCl4 or cerulein.{33437,33439}
Brand:CaymanSKU:-Available on backorder
CWHM12 is an analog of RGD peptide (Item No. 14501), a tripeptide that inhibits integrin-ligand interactions in studies related to cell adhesion, migration, growth, and differentiation.{5588} CWHM12 selectively inhibits αv integrins (IC50s = 1.8, 0.8, 61, 1.5, and 0.2 nM for αvβ1, αvβ3, αvβ5, αvβ6, and αvβ8, respectively) over αIIbβ3, α2β1, and α10β1.{33437} CWHM 12 attenuates liver, lung, and pancreatic fibrosis in mice treated with CCl4 or cerulein.{33437,33439}
Brand:CaymanSKU:-Available on backorder
CX-4945 is a potent, orally bioavailable inhibitor of casein kinase 2 (CK2; Ki = 0.38 nM) that competes with ATP by filling the small ATP binding site on the catalytic CK2α subunit, conferring selectivity.{27517,27516,27518} It inhibits proliferation in a panel of cancer cell lines that overexpress CK2 and prevents tumor growth of breast and pancreatic cancer cell xenografts in mice.{27518} CX-4945 blocks survival and induces apoptosis in cancer stem cells and is effective against glioblastomas and acute myeloid leukemia cells.{27520,27519} CX-4945 also inhibits Cdc2-like kinases (Clk; IC50s = 82.3, 3.8, and 90 nM for Clk1, Clk2, and Clk3, respectively), interfering with alternative splicing.{26173}
Brand:CaymanSKU:-Out of stock
CX-4945 is a potent, orally bioavailable inhibitor of casein kinase 2 (CK2; Ki = 0.38 nM) that competes with ATP by filling the small ATP binding site on the catalytic CK2α subunit, conferring selectivity.{27517,27516,27518} It inhibits proliferation in a panel of cancer cell lines that overexpress CK2 and prevents tumor growth of breast and pancreatic cancer cell xenografts in mice.{27518} CX-4945 blocks survival and induces apoptosis in cancer stem cells and is effective against glioblastomas and acute myeloid leukemia cells.{27520,27519} CX-4945 also inhibits Cdc2-like kinases (Clk; IC50s = 82.3, 3.8, and 90 nM for Clk1, Clk2, and Clk3, respectively), interfering with alternative splicing.{26173}
Brand:CaymanSKU:-Out of stock
CX-4945 is a potent, orally bioavailable inhibitor of casein kinase 2 (CK2; Ki = 0.38 nM) that competes with ATP by filling the small ATP binding site on the catalytic CK2α subunit, conferring selectivity.{27517,27516,27518} It inhibits proliferation in a panel of cancer cell lines that overexpress CK2 and prevents tumor growth of breast and pancreatic cancer cell xenografts in mice.{27518} CX-4945 blocks survival and induces apoptosis in cancer stem cells and is effective against glioblastomas and acute myeloid leukemia cells.{27520,27519} CX-4945 also inhibits Cdc2-like kinases (Clk; IC50s = 82.3, 3.8, and 90 nM for Clk1, Clk2, and Clk3, respectively), interfering with alternative splicing.{26173}
Brand:CaymanSKU:-Out of stock
CX-4945 is a potent, orally bioavailable inhibitor of casein kinase 2 (CK2; Ki = 0.38 nM) that competes with ATP by filling the small ATP binding site on the catalytic CK2α subunit, conferring selectivity.{27517,27516,27518} It inhibits proliferation in a panel of cancer cell lines that overexpress CK2 and prevents tumor growth of breast and pancreatic cancer cell xenografts in mice.{27518} CX-4945 blocks survival and induces apoptosis in cancer stem cells and is effective against glioblastomas and acute myeloid leukemia cells.{27520,27519} CX-4945 also inhibits Cdc2-like kinases (Clk; IC50s = 82.3, 3.8, and 90 nM for Clk1, Clk2, and Clk3, respectively), interfering with alternative splicing.{26173}
Brand:CaymanSKU:-Out of stock
CX-516 is an AMPA receptor modulator.{39729,39730} It increases the mean open time of AMPA receptors which increases the amplitude of trisynaptic responses to presynaptic stimulation in rat hippocampal slices. In vivo, CX-516 (10-50 mg/kg) accelerates acquisition of a conditioned fear response in rats in a dose-dependent manner.{39730} It enhances performance in a spatial, delayed nonmatch-to-sample (DNMS) test in rats.{39731} CX-516 also reverses dominance between initially dominant and submissive rat pairs, a marker of antidepressant-like activity, in the rat reduction of submissive behavior model.{39732}
Brand:CaymanSKU:- CX-516 is an AMPA receptor modulator.{39729,39730} It increases the mean open time of AMPA receptors which increases the amplitude of trisynaptic responses to presynaptic stimulation in rat hippocampal slices. In vivo, CX-516 (10-50 mg/kg) accelerates acquisition of a conditioned fear response in rats in a dose-dependent manner.{39730} It enhances performance in a spatial, delayed nonmatch-to-sample (DNMS) test in rats.{39731} CX-516 also reverses dominance between initially dominant and submissive rat pairs, a marker of antidepressant-like activity, in the rat reduction of submissive behavior model.{39732}
Brand:CaymanSKU:- CX-516 is an AMPA receptor modulator.{39729,39730} It increases the mean open time of AMPA receptors which increases the amplitude of trisynaptic responses to presynaptic stimulation in rat hippocampal slices. In vivo, CX-516 (10-50 mg/kg) accelerates acquisition of a conditioned fear response in rats in a dose-dependent manner.{39730} It enhances performance in a spatial, delayed nonmatch-to-sample (DNMS) test in rats.{39731} CX-516 also reverses dominance between initially dominant and submissive rat pairs, a marker of antidepressant-like activity, in the rat reduction of submissive behavior model.{39732}
Brand:CaymanSKU:- CX-516 is an AMPA receptor modulator.{39729,39730} It increases the mean open time of AMPA receptors which increases the amplitude of trisynaptic responses to presynaptic stimulation in rat hippocampal slices. In vivo, CX-516 (10-50 mg/kg) accelerates acquisition of a conditioned fear response in rats in a dose-dependent manner.{39730} It enhances performance in a spatial, delayed nonmatch-to-sample (DNMS) test in rats.{39731} CX-516 also reverses dominance between initially dominant and submissive rat pairs, a marker of antidepressant-like activity, in the rat reduction of submissive behavior model.{39732}
Brand:CaymanSKU:-
CX-5461 is an inhibitor of ribosomal RNA (rRNA) synthesis. It selectively inhibits RNA polymerase I-driven transcription of rRNA in HCT116, A375, and MIA PaCa-2 tumor cells (IC50s = 142, 113, and 54 nM, respectively) without affecting RNA polymerase II (IC50 > 25µM), DNA replication, or protein translation.{30876,30877} At 50 mg/kg, CX-5461 demonstrates in vivo antitumor activity against human solid tumors in mouse xenograft models.{30876}
Brand:CaymanSKU:-Available on backorder
CX-5461 is an inhibitor of ribosomal RNA (rRNA) synthesis. It selectively inhibits RNA polymerase I-driven transcription of rRNA in HCT116, A375, and MIA PaCa-2 tumor cells (IC50s = 142, 113, and 54 nM, respectively) without affecting RNA polymerase II (IC50 > 25µM), DNA replication, or protein translation.{30876,30877} At 50 mg/kg, CX-5461 demonstrates in vivo antitumor activity against human solid tumors in mouse xenograft models.{30876}
Brand:CaymanSKU:-Available on backorder
CX-5461 is an inhibitor of ribosomal RNA (rRNA) synthesis. It selectively inhibits RNA polymerase I-driven transcription of rRNA in HCT116, A375, and MIA PaCa-2 tumor cells (IC50s = 142, 113, and 54 nM, respectively) without affecting RNA polymerase II (IC50 > 25µM), DNA replication, or protein translation.{30876,30877} At 50 mg/kg, CX-5461 demonstrates in vivo antitumor activity against human solid tumors in mouse xenograft models.{30876}
Brand:CaymanSKU:-Available on backorder
CX-5461 is an inhibitor of ribosomal RNA (rRNA) synthesis. It selectively inhibits RNA polymerase I-driven transcription of rRNA in HCT116, A375, and MIA PaCa-2 tumor cells (IC50s = 142, 113, and 54 nM, respectively) without affecting RNA polymerase II (IC50 > 25µM), DNA replication, or protein translation.{30876,30877} At 50 mg/kg, CX-5461 demonstrates in vivo antitumor activity against human solid tumors in mouse xenograft models.{30876}
Brand:CaymanSKU:-Available on backorder
The family of Pim (Provirus Integration site for Moloney murine leukemia virus) proteins are serine/threonine kinases involved in cell survival and cell proliferation. CX-6258 is a potent, reversible inhibitor of Pim-1, -2, and -3 (IC50s = 5, 25, and 16 nM, respectively).{28838} It demonstrates excellent selectivity, inhibiting only FLT3 from a panel of 107 additional kinases. CX-6258 dose-dependently blocks the phosphorylation of the Pim targets Bad, 4E-BP1, and NKX3.1.{28838,28839} It acts synergistically with the chemotherapeutics doxorubicin and paclitaxel, presumably because CX-6258 impairs Pim-mediated enhanced expression of P-glycoprotein.{28838} CX-6258 is orally bioavailable and inhibits the growth of MV4-11 xenografts in mice.{28838}
Brand:CaymanSKU:- The family of Pim (Provirus Integration site for Moloney murine leukemia virus) proteins are serine/threonine kinases involved in cell survival and cell proliferation. CX-6258 is a potent, reversible inhibitor of Pim-1, -2, and -3 (IC50s = 5, 25, and 16 nM, respectively).{28838} It demonstrates excellent selectivity, inhibiting only FLT3 from a panel of 107 additional kinases. CX-6258 dose-dependently blocks the phosphorylation of the Pim targets Bad, 4E-BP1, and NKX3.1.{28838,28839} It acts synergistically with the chemotherapeutics doxorubicin and paclitaxel, presumably because CX-6258 impairs Pim-mediated enhanced expression of P-glycoprotein.{28838} CX-6258 is orally bioavailable and inhibits the growth of MV4-11 xenografts in mice.{28838}
Brand:CaymanSKU:- The family of Pim (Provirus Integration site for Moloney murine leukemia virus) proteins are serine/threonine kinases involved in cell survival and cell proliferation. CX-6258 is a potent, reversible inhibitor of Pim-1, -2, and -3 (IC50s = 5, 25, and 16 nM, respectively).{28838} It demonstrates excellent selectivity, inhibiting only FLT3 from a panel of 107 additional kinases. CX-6258 dose-dependently blocks the phosphorylation of the Pim targets Bad, 4E-BP1, and NKX3.1.{28838,28839} It acts synergistically with the chemotherapeutics doxorubicin and paclitaxel, presumably because CX-6258 impairs Pim-mediated enhanced expression of P-glycoprotein.{28838} CX-6258 is orally bioavailable and inhibits the growth of MV4-11 xenografts in mice.{28838}
Brand:CaymanSKU:- The family of Pim (Provirus Integration site for Moloney murine leukemia virus) proteins are serine/threonine kinases involved in cell survival and cell proliferation. CX-6258 is a potent, reversible inhibitor of Pim-1, -2, and -3 (IC50s = 5, 25, and 16 nM, respectively).{28838} It demonstrates excellent selectivity, inhibiting only FLT3 from a panel of 107 additional kinases. CX-6258 dose-dependently blocks the phosphorylation of the Pim targets Bad, 4E-BP1, and NKX3.1.{28838,28839} It acts synergistically with the chemotherapeutics doxorubicin and paclitaxel, presumably because CX-6258 impairs Pim-mediated enhanced expression of P-glycoprotein.{28838} CX-6258 is orally bioavailable and inhibits the growth of MV4-11 xenografts in mice.{28838}
Brand:CaymanSKU:-
CXCR3 antagonist 6c is an antagonist of chemokine (C-X-C motif) receptor 3 (CXCR3).{52334} It inhibits calcium mobilization induced by chemokine (C-X-C motif) ligand 11 (CXCL11) in HEK293 cells expressing the human receptor (IC50 = 0.06 µM). It is selective for CXCR3 over a panel of 14 human G protein-coupled receptors at 10 µM. CXCR3 antagonist 6c inhibits CXCR3-mediated migration of isolated human T cells (IC50 = ~100 nM).
Brand:CaymanSKU:29731 - 1 mgAvailable on backorder
CXCR3 antagonist 6c is an antagonist of chemokine (C-X-C motif) receptor 3 (CXCR3).{52334} It inhibits calcium mobilization induced by chemokine (C-X-C motif) ligand 11 (CXCL11) in HEK293 cells expressing the human receptor (IC50 = 0.06 µM). It is selective for CXCR3 over a panel of 14 human G protein-coupled receptors at 10 µM. CXCR3 antagonist 6c inhibits CXCR3-mediated migration of isolated human T cells (IC50 = ~100 nM).
Brand:CaymanSKU:29731 - 10 mgAvailable on backorder
CXCR3 antagonist 6c is an antagonist of chemokine (C-X-C motif) receptor 3 (CXCR3).{52334} It inhibits calcium mobilization induced by chemokine (C-X-C motif) ligand 11 (CXCL11) in HEK293 cells expressing the human receptor (IC50 = 0.06 µM). It is selective for CXCR3 over a panel of 14 human G protein-coupled receptors at 10 µM. CXCR3 antagonist 6c inhibits CXCR3-mediated migration of isolated human T cells (IC50 = ~100 nM).
Brand:CaymanSKU:29731 - 5 mgAvailable on backorder
CXD101 is a histone deacetylase (HDAC) inhibitor with structural similarities to mocetinostat (Item No. 18287), MS-275 (Item No. 13284), and JNJ-26481585 (Item No. 14088). The biological activity of CXD101 has not been published.
Brand:CaymanSKU:21159 -Out of stock
CXD101 is a histone deacetylase (HDAC) inhibitor with structural similarities to mocetinostat (Item No. 18287), MS-275 (Item No. 13284), and JNJ-26481585 (Item No. 14088). The biological activity of CXD101 has not been published.
Brand:CaymanSKU:21159 -Out of stock
CXD101 is a histone deacetylase (HDAC) inhibitor with structural similarities to mocetinostat (Item No. 18287), MS-275 (Item No. 13284), and JNJ-26481585 (Item No. 14088). The biological activity of CXD101 has not been published.
Brand:CaymanSKU:21159 -Out of stock
CXD101 is a histone deacetylase (HDAC) inhibitor with structural similarities to mocetinostat (Item No. 18287), MS-275 (Item No. 13284), and JNJ-26481585 (Item No. 14088). The biological activity of CXD101 has not been published.
Brand:CaymanSKU:21159 -Out of stock
Cy3 is a cyanine-containing fluorochrome.{42160} It has commonly been conjugated to secondary antibodies for use in immunocytochemistry and immunohistochemistry applications. Cy3 displays excitation/emission maxima of 550/570 nm, respectively.
Brand:CaymanSKU:30392 - 1 mgAvailable on backorder
Cy3 is a cyanine-containing fluorochrome.{42160} It has commonly been conjugated to secondary antibodies for use in immunocytochemistry and immunohistochemistry applications. Cy3 displays excitation/emission maxima of 550/570 nm, respectively.
Brand:CaymanSKU:30392 - 10 mgAvailable on backorder
Cy3 is a cyanine-containing fluorochrome.{42160} It has commonly been conjugated to secondary antibodies for use in immunocytochemistry and immunohistochemistry applications. Cy3 displays excitation/emission maxima of 550/570 nm, respectively.
Brand:CaymanSKU:30392 - 25 mgAvailable on backorder
Cy3 is a cyanine-containing fluorochrome.{42160} It has commonly been conjugated to secondary antibodies for use in immunocytochemistry and immunohistochemistry applications. Cy3 displays excitation/emission maxima of 550/570 nm, respectively.
Brand:CaymanSKU:30392 - 5 mgAvailable on backorder
Cy5-SE is a hydrophilic amine-reactive fluorescent probe.{60102} It displays excitation/emission maxima of 646/662 nm, respectively. Cy5-SE-conjugated ligands have been used in the characterization of hematopoietic tumor microenvironments.
Brand:CaymanSKU:30387 - 1 mgAvailable on backorder
Cy5-SE is a hydrophilic amine-reactive fluorescent probe.{60102} It displays excitation/emission maxima of 646/662 nm, respectively. Cy5-SE-conjugated ligands have been used in the characterization of hematopoietic tumor microenvironments.
Brand:CaymanSKU:30387 - 10 mgAvailable on backorder
Cy5-SE is a hydrophilic amine-reactive fluorescent probe.{60102} It displays excitation/emission maxima of 646/662 nm, respectively. Cy5-SE-conjugated ligands have been used in the characterization of hematopoietic tumor microenvironments.
Brand:CaymanSKU:30387 - 5 mgAvailable on backorder
Cyanidin is a natural anthocyanidin found in a variety of fruits and vegetables. This polyphenolic compound is a flavonoid with significant antioxidant activity.{23823} Cyanidin and its glycosides have vasoprotective effects and can interfere with inflammation, carcinogenesis, obesity, and diabetes.{20649,23825,23824}
Brand:CaymanSKU:- Cyanidin is a natural anthocyanidin found in a variety of fruits and vegetables. This polyphenolic compound is a flavonoid with significant antioxidant activity.{23823} Cyanidin and its glycosides have vasoprotective effects and can interfere with inflammation, carcinogenesis, obesity, and diabetes.{20649,23825,23824}
Brand:CaymanSKU:- Cyanidin is a natural anthocyanidin found in a variety of fruits and vegetables. This polyphenolic compound is a flavonoid with significant antioxidant activity.{23823} Cyanidin and its glycosides have vasoprotective effects and can interfere with inflammation, carcinogenesis, obesity, and diabetes.{20649,23825,23824}
Brand:CaymanSKU:- Cyanidin is a natural anthocyanidin found in a variety of fruits and vegetables. This polyphenolic compound is a flavonoid with significant antioxidant activity.{23823} Cyanidin and its glycosides have vasoprotective effects and can interfere with inflammation, carcinogenesis, obesity, and diabetes.{20649,23825,23824}
Brand:CaymanSKU:-
Cyanidin 3-O-arabinoside is an anthocyanin antioxidant that has been found in eggplant.{43632} It scavenges radicals in a Trolox equivalent antioxidant capacity (TEAC) assay.
Brand:CaymanSKU:26183 - 1 mgAvailable on backorder