Chemicals
Showing 14851–15000 of 41137 results
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cis-10-Nonadecenoic acid is a C19:1 monounsaturated fatty acid. It has been examined for potential antitumor activity and was reported to inhibit HL-60 cell proliferation with an IC50 value of 295 µM and to prevent LPS-induced tumor necrosis factor production from mouse macrophages.{31488} Furthermore, long-chain fatty acids, such as cis-10-nonadecenoic acid, have been shown to inhibit p53 activity.{31533}
Brand:CaymanSKU:19749 -Available on backorder
cis-10-Nonadecenoic acid methyl ester is a fatty acid methyl ester.{45155} It has been used as a standard for the quantification of cis-nonadecenoic acid (Item No. 19749) in chromatography applications.{45155,45156}
Brand:CaymanSKU:26733 - 100 mgAvailable on backorder
cis-10-Nonadecenoic acid methyl ester is a fatty acid methyl ester.{45155} It has been used as a standard for the quantification of cis-nonadecenoic acid (Item No. 19749) in chromatography applications.{45155,45156}
Brand:CaymanSKU:26733 - 250 mgAvailable on backorder
cis-10-Nonadecenoic acid methyl ester is a fatty acid methyl ester.{45155} It has been used as a standard for the quantification of cis-nonadecenoic acid (Item No. 19749) in chromatography applications.{45155,45156}
Brand:CaymanSKU:26733 - 50 mgAvailable on backorder
cis-12-Octadecenoic acid is a monounsaturated C-18 fatty acid. It is a positional isomer of oleic acid. The methyl ester is a more lipid soluble form of the free acid that can be used as a standard for analysis.
Brand:CaymanSKU:10010180 - 10 mgAvailable on backorder
cis-12-Octadecenoic acid is a monounsaturated C-18 fatty acid. It is a positional isomer of oleic acid. The methyl ester is a more lipid soluble form of the free acid that can be used as a standard for analysis.
Brand:CaymanSKU:10010180 - 5 mgAvailable on backorder
cis-12-Octadecenoic acid is a monounsaturated C-18 fatty acid. It is a positional isomer of oleic acid. The methyl ester is a more lipid soluble form of the free acid that can be used as a standard for analysis.
Brand:CaymanSKU:10010180 - 50 mgAvailable on backorder
Microorganisms commonly accumulate at interfaces as part of biofilms held together by a matrix of hydrated extracellular polymeric substances.{21408} cis-2-Decenoic acid is an unsaturated short chain fatty acid that is secreted by P. aeruginosa and induces a dispersion response in biofilms formed by gram-negative and gram-positive bacteria, as well as by the yeast C. albicans.{21407} It effectively promotes dispersion of P. aeruginosa biofilms over a concentration range of 1.0 to 10 nM.{21407}
Brand:CaymanSKU:11966 - 1 mgAvailable on backorder
Microorganisms commonly accumulate at interfaces as part of biofilms held together by a matrix of hydrated extracellular polymeric substances.{21408} cis-2-Decenoic acid is an unsaturated short chain fatty acid that is secreted by P. aeruginosa and induces a dispersion response in biofilms formed by gram-negative and gram-positive bacteria, as well as by the yeast C. albicans.{21407} It effectively promotes dispersion of P. aeruginosa biofilms over a concentration range of 1.0 to 10 nM.{21407}
Brand:CaymanSKU:11966 - 10 mgAvailable on backorder
Microorganisms commonly accumulate at interfaces as part of biofilms held together by a matrix of hydrated extracellular polymeric substances.{21408} cis-2-Decenoic acid is an unsaturated short chain fatty acid that is secreted by P. aeruginosa and induces a dispersion response in biofilms formed by gram-negative and gram-positive bacteria, as well as by the yeast C. albicans.{21407} It effectively promotes dispersion of P. aeruginosa biofilms over a concentration range of 1.0 to 10 nM.{21407}
Brand:CaymanSKU:11966 - 25 mgAvailable on backorder
Microorganisms commonly accumulate at interfaces as part of biofilms held together by a matrix of hydrated extracellular polymeric substances.{21408} cis-2-Decenoic acid is an unsaturated short chain fatty acid that is secreted by P. aeruginosa and induces a dispersion response in biofilms formed by gram-negative and gram-positive bacteria, as well as by the yeast C. albicans.{21407} It effectively promotes dispersion of P. aeruginosa biofilms over a concentration range of 1.0 to 10 nM.{21407}
Brand:CaymanSKU:11966 - 5 mgAvailable on backorder
cis-4,10,13,16-Docosatetraenoic acid is a long chain polyunsaturated fatty acid. It is a minor fatty acid component of rat testis lipids.{14216}
Brand:CaymanSKU:10007289 - 1 mgAvailable on backorder
cis-4,10,13,16-Docosatetraenoic acid is a long chain polyunsaturated fatty acid. It is a minor fatty acid component of rat testis lipids.{14216}
Brand:CaymanSKU:10007289 - 10 mgAvailable on backorder
cis-4,10,13,16-Docosatetraenoic acid is a long chain polyunsaturated fatty acid. It is a minor fatty acid component of rat testis lipids.{14216}
Brand:CaymanSKU:10007289 - 5 mgAvailable on backorder
cis-6-Hexadecenoic acid is a monounsaturated fatty acid and is one of the primary fatty acids in human skin.{42782} cis-6-Hexadecenoic acid levels are increased in isolated sebum from the face and back of patients with acne.{42783} In contrast, levels are decreased in the non-lesional skin and isolated sebum of atopic dermatitis patients, which correlates with an increase in S. aureus in the sebum.{42782} It is active against S. aureus in vitro when used at a concentration of 5 µg/ml at pH 5.5.{42784} cis-6-Hexadecenoic acid disrupts membrane integrity, the proton motive force, increases membrane fluidity, and inhibits the electron transport chain in S. aureus. [Matreya, LLC. Catalog No. 1243]
Brand:CaymanSKU:9001845 - 10 mgAvailable on backorder
cis-6-Hexadecenoic acid is a monounsaturated fatty acid and is one of the primary fatty acids in human skin.{42782} cis-6-Hexadecenoic acid levels are increased in isolated sebum from the face and back of patients with acne.{42783} In contrast, levels are decreased in the non-lesional skin and isolated sebum of atopic dermatitis patients, which correlates with an increase in S. aureus in the sebum.{42782} It is active against S. aureus in vitro when used at a concentration of 5 µg/ml at pH 5.5.{42784} cis-6-Hexadecenoic acid disrupts membrane integrity, the proton motive force, increases membrane fluidity, and inhibits the electron transport chain in S. aureus. [Matreya, LLC. Catalog No. 1243]
Brand:CaymanSKU:9001845 - 25 mgAvailable on backorder
cis-6-Hexadecenoic acid is a monounsaturated fatty acid and is one of the primary fatty acids in human skin.{42782} cis-6-Hexadecenoic acid levels are increased in isolated sebum from the face and back of patients with acne.{42783} In contrast, levels are decreased in the non-lesional skin and isolated sebum of atopic dermatitis patients, which correlates with an increase in S. aureus in the sebum.{42782} It is active against S. aureus in vitro when used at a concentration of 5 µg/ml at pH 5.5.{42784} cis-6-Hexadecenoic acid disrupts membrane integrity, the proton motive force, increases membrane fluidity, and inhibits the electron transport chain in S. aureus. [Matreya, LLC. Catalog No. 1243]
Brand:CaymanSKU:9001845 - 5 mgAvailable on backorder
Mono-unsaturated fatty acids are components of the cellular membranes of autotrophic bacteria. The specific composition and abundance of membrane fatty acids can be used to identify specific genera of bacterial populations in natural environments (e.g., mining lakes, etc.).{13903} cis-7-Hexadecenoic acid has been isolated from autotrophic bacterial cultures associated with the accumulation of sulfate in biofilters. This indicates they originate from a sulfide-oxidizing autotrophic organism. To date, however, this fatty acid has only been detected in strains of the genera Nitrospira, which are nitrite oxidizing autotrophic bacteria.
Brand:CaymanSKU:10007290 - 10 mgAvailable on backorder
Mono-unsaturated fatty acids are components of the cellular membranes of autotrophic bacteria. The specific composition and abundance of membrane fatty acids can be used to identify specific genera of bacterial populations in natural environments (e.g., mining lakes, etc.).{13903} cis-7-Hexadecenoic acid has been isolated from autotrophic bacterial cultures associated with the accumulation of sulfate in biofilters. This indicates they originate from a sulfide-oxidizing autotrophic organism. To date, however, this fatty acid has only been detected in strains of the genera Nitrospira, which are nitrite oxidizing autotrophic bacteria.
Brand:CaymanSKU:10007290 - 100 mgAvailable on backorder
Mono-unsaturated fatty acids are components of the cellular membranes of autotrophic bacteria. The specific composition and abundance of membrane fatty acids can be used to identify specific genera of bacterial populations in natural environments (e.g., mining lakes, etc.).{13903} cis-7-Hexadecenoic acid has been isolated from autotrophic bacterial cultures associated with the accumulation of sulfate in biofilters. This indicates they originate from a sulfide-oxidizing autotrophic organism. To date, however, this fatty acid has only been detected in strains of the genera Nitrospira, which are nitrite oxidizing autotrophic bacteria.
Brand:CaymanSKU:10007290 - 5 mgAvailable on backorder
Mono-unsaturated fatty acids are components of the cellular membranes of autotrophic bacteria. The specific composition and abundance of membrane fatty acids can be used to identify specific genera of bacterial populations in natural environments (e.g., mining lakes, etc.).{13903} cis-7-Hexadecenoic acid has been isolated from autotrophic bacterial cultures associated with the accumulation of sulfate in biofilters. This indicates they originate from a sulfide-oxidizing autotrophic organism. To date, however, this fatty acid has only been detected in strains of the genera Nitrospira, which are nitrite oxidizing autotrophic bacteria.
Brand:CaymanSKU:10007290 - 50 mgAvailable on backorder
Mono-unsaturated fatty acids are components of the cellular membranes of autotrophic bacteria. The specific composition and abundance of membrane fatty acids can be used to identify specific genera of bacterial populations in natural environments (e.g., mining lakes, etc.).{13903} cis-7-Hexadecenoic acid methyl ester is a complement to cis-7-hexadecenoic acid. The non-esterified molecule has been isolated from autotrophic bacterial cultures associated with the accumulation of sulfate in biofilters. This indicates they originate from a sulfide-oxidizing autotrophic organism. To date, however, this fatty acid has only been detected in strains of the genera Nitrospira, which are nitrite oxidizing autotrophic bacteria.
Brand:CaymanSKU:10006864 - 10 mgAvailable on backorder
Mono-unsaturated fatty acids are components of the cellular membranes of autotrophic bacteria. The specific composition and abundance of membrane fatty acids can be used to identify specific genera of bacterial populations in natural environments (e.g., mining lakes, etc.).{13903} cis-7-Hexadecenoic acid methyl ester is a complement to cis-7-hexadecenoic acid. The non-esterified molecule has been isolated from autotrophic bacterial cultures associated with the accumulation of sulfate in biofilters. This indicates they originate from a sulfide-oxidizing autotrophic organism. To date, however, this fatty acid has only been detected in strains of the genera Nitrospira, which are nitrite oxidizing autotrophic bacteria.
Brand:CaymanSKU:10006864 - 25 mgAvailable on backorder
Mono-unsaturated fatty acids are components of the cellular membranes of autotrophic bacteria. The specific composition and abundance of membrane fatty acids can be used to identify specific genera of bacterial populations in natural environments (e.g., mining lakes, etc.).{13903} cis-7-Hexadecenoic acid methyl ester is a complement to cis-7-hexadecenoic acid. The non-esterified molecule has been isolated from autotrophic bacterial cultures associated with the accumulation of sulfate in biofilters. This indicates they originate from a sulfide-oxidizing autotrophic organism. To date, however, this fatty acid has only been detected in strains of the genera Nitrospira, which are nitrite oxidizing autotrophic bacteria.
Brand:CaymanSKU:10006864 - 5 mgAvailable on backorder
Mono-unsaturated fatty acids are components of the cellular membranes of autotrophic bacteria. The specific composition and abundance of membrane fatty acids can be used to identify specific genera of bacterial populations in natural environments (e.g., mining lakes, etc.).{13903} cis-7-Hexadecenoic acid methyl ester is a complement to cis-7-hexadecenoic acid. The non-esterified molecule has been isolated from autotrophic bacterial cultures associated with the accumulation of sulfate in biofilters. This indicates they originate from a sulfide-oxidizing autotrophic organism. To date, however, this fatty acid has only been detected in strains of the genera Nitrospira, which are nitrite oxidizing autotrophic bacteria.
Brand:CaymanSKU:10006864 - 50 mgAvailable on backorder
cis-8-Octadecenoic acid is a monounsaturated fatty acid and an isomer of oleic acid (Item Nos. 90260 | 24659), trans-vaccenic acid (Item No. 15301), trans-petroselinic acid (Item No. 20026), and cis-petroselinic acid (Item No. 20024). It has been found in partially hydrogenated vegetable oil and milk fat.{42751}
Brand:CaymanSKU:27447 - 1 mgAvailable on backorder
cis-8-Octadecenoic acid is a monounsaturated fatty acid and an isomer of oleic acid (Item Nos. 90260 | 24659), trans-vaccenic acid (Item No. 15301), trans-petroselinic acid (Item No. 20026), and cis-petroselinic acid (Item No. 20024). It has been found in partially hydrogenated vegetable oil and milk fat.{42751}
Brand:CaymanSKU:27447 - 5 mgAvailable on backorder
cis-8-Octadecenoic acid is a monounsaturated fatty acid and an isomer of oleic acid (Item Nos. 90260 | 24659), trans-vaccenic acid (Item No. 15301), trans-petroselinic acid (Item No. 20026), and cis-petroselinic acid (Item No. 20024). It has been found in partially hydrogenated vegetable oil and milk fat.{42751}
Brand:CaymanSKU:27447 - 500 µgAvailable on backorder
cis-9,10-Methyleneoctadecanoic acid is a cyclopropane fatty acid that has been found in bacteria and the digestive gland of P. globosa.{38966,38967,38968} It is a component of S. aureus cell membranes and levels decrease upon treatment with carvacrol.{38967} cis-9,10-Methyleneoctadecanoic acid is secreted by H. pylori and enhances histamine- and dibutyryl cAMP-stimulated acid secretion in isolated guinea pig parietal cells.{38969} It also activates protein kinase C (PKC) in a calcium-dependent manner. [Matreya, LLC. Catalog No. 1822]
Brand:CaymanSKU:24824 - 25 mgAvailable on backorder
cis-9,10-Methyleneoctadecanoic acid methyl ester is a cyclopropane fatty acid methyl ester.{38970} It stimulates DNA synthesis in rat hepatocytes. cis-9,10-Methyleneoctadecanoic acid methyl ester has been used as a standard for the quantification of cis-9,10-methyleneoctadecanoic acid (Item No. 24824) in bacterial membranes by co-chromatography.{38971} [Matreya, LLC. Catalog No. 1823]
Brand:CaymanSKU:24825 - 25 mgAvailable on backorder
Matrix metalloproteinases (MMPs) belong to a family of proteases that play a crucial role in tissue remodeling and repair by degrading extracellular matrix proteins, thus enabling cell migration.{16569} Overexpression of MMPs are linked to diseases such as cancer, arthritis, osteoporosis, and arteriosclerosis. cis-ACCP is a reversible and competitive inhibitor of type IV collagen-specific MMP-2 and MMP-9 with preference towards MMP-2 (IC50 = 4 and 20 µM, respectively).{15739} At 100 µM, cis-ACCP prevents 90% of tumor cell invasion across matrigel-coated membranes in vitro.{15739}
Brand:CaymanSKU:10012583 - 1 mgAvailable on backorder
Matrix metalloproteinases (MMPs) belong to a family of proteases that play a crucial role in tissue remodeling and repair by degrading extracellular matrix proteins, thus enabling cell migration.{16569} Overexpression of MMPs are linked to diseases such as cancer, arthritis, osteoporosis, and arteriosclerosis. cis-ACCP is a reversible and competitive inhibitor of type IV collagen-specific MMP-2 and MMP-9 with preference towards MMP-2 (IC50 = 4 and 20 µM, respectively).{15739} At 100 µM, cis-ACCP prevents 90% of tumor cell invasion across matrigel-coated membranes in vitro.{15739}
Brand:CaymanSKU:10012583 - 10 mgAvailable on backorder
Matrix metalloproteinases (MMPs) belong to a family of proteases that play a crucial role in tissue remodeling and repair by degrading extracellular matrix proteins, thus enabling cell migration.{16569} Overexpression of MMPs are linked to diseases such as cancer, arthritis, osteoporosis, and arteriosclerosis. cis-ACCP is a reversible and competitive inhibitor of type IV collagen-specific MMP-2 and MMP-9 with preference towards MMP-2 (IC50 = 4 and 20 µM, respectively).{15739} At 100 µM, cis-ACCP prevents 90% of tumor cell invasion across matrigel-coated membranes in vitro.{15739}
Brand:CaymanSKU:10012583 - 5 mgAvailable on backorder
Matrix metalloproteinases (MMPs) belong to a family of proteases that play a crucial role in tissue remodeling and repair by degrading extracellular matrix proteins, thus enabling cell migration.{16569} Overexpression of MMPs are linked to diseases such as cancer, arthritis, osteoporosis, and arteriosclerosis. cis-ACCP is a reversible and competitive inhibitor of type IV collagen-specific MMP-2 and MMP-9 with preference towards MMP-2 (IC50 = 4 and 20 µM, respectively).{15739} At 100 µM, cis-ACCP prevents 90% of tumor cell invasion across matrigel-coated membranes in vitro.{15739}
Brand:CaymanSKU:10012583 - 50 mgAvailable on backorder
cis-Entacapone is a metabolite of the catechol-O-methyltransferase (COMT) inhibitor entacapone (Item No. 14153).{48396} It is also a potential impurity found in commercial preparations of entacapone and a degradant of entacapone formed by UV light exposure.{48397,48398}
Brand:CaymanSKU:28046 - 1 mgAvailable on backorder
cis-Entacapone is a metabolite of the catechol-O-methyltransferase (COMT) inhibitor entacapone (Item No. 14153).{48396} It is also a potential impurity found in commercial preparations of entacapone and a degradant of entacapone formed by UV light exposure.{48397,48398}
Brand:CaymanSKU:28046 - 5 mgAvailable on backorder
cis-Flupenthixol is a typical antipsychotic, a dopamine D2 receptor antagonist (Ki = 0.38 nM), and an inverse agonist at the serotonin (5-HT) receptor subtype 5-HT2A (Ki = 7 nM).{26444} In vivo, cis-flupenthixol (0.5 mg/kg, i.p.) reduces cocaine-induced locomotor activity and prevents development of conditioned place preferences for the immediate effects of intravenously administered cocaine without affecting development of conditioned place aversions in rats.{42313} cis-Flupenthixol also inhibits acid sphingomyelinase activity by 81.8% when used at a concentration of 10 mM.{26583}
Brand:CaymanSKU:-Available on backorder
cis-Flupenthixol is a typical antipsychotic, a dopamine D2 receptor antagonist (Ki = 0.38 nM), and an inverse agonist at the serotonin (5-HT) receptor subtype 5-HT2A (Ki = 7 nM).{26444} In vivo, cis-flupenthixol (0.5 mg/kg, i.p.) reduces cocaine-induced locomotor activity and prevents development of conditioned place preferences for the immediate effects of intravenously administered cocaine without affecting development of conditioned place aversions in rats.{42313} cis-Flupenthixol also inhibits acid sphingomyelinase activity by 81.8% when used at a concentration of 10 mM.{26583}
Brand:CaymanSKU:-Available on backorder
cis-Flupenthixol is a typical antipsychotic, a dopamine D2 receptor antagonist (Ki = 0.38 nM), and an inverse agonist at the serotonin (5-HT) receptor subtype 5-HT2A (Ki = 7 nM).{26444} In vivo, cis-flupenthixol (0.5 mg/kg, i.p.) reduces cocaine-induced locomotor activity and prevents development of conditioned place preferences for the immediate effects of intravenously administered cocaine without affecting development of conditioned place aversions in rats.{42313} cis-Flupenthixol also inhibits acid sphingomyelinase activity by 81.8% when used at a concentration of 10 mM.{26583}
Brand:CaymanSKU:-Available on backorder
cis-Flupenthixol is a typical antipsychotic, a dopamine D2 receptor antagonist (Ki = 0.38 nM), and an inverse agonist at the serotonin (5-HT) receptor subtype 5-HT2A (Ki = 7 nM).{26444} In vivo, cis-flupenthixol (0.5 mg/kg, i.p.) reduces cocaine-induced locomotor activity and prevents development of conditioned place preferences for the immediate effects of intravenously administered cocaine without affecting development of conditioned place aversions in rats.{42313} cis-Flupenthixol also inhibits acid sphingomyelinase activity by 81.8% when used at a concentration of 10 mM.{26583}
Brand:CaymanSKU:-Available on backorder
cis-Parinaric acid is a naturally occurring polyunsaturated fatty acid containing an unusual conjugated (Z,E,E,Z) tetraene. This chromophore provides for a natural fluorescence at 432 nm with an excitation wavelength at 320 nm. cis-Parinaric acid occurs naturally in the seeds of the Makita tree, a tropical rainforest tree indigenous to Fiji. Makita seeds are inedible, and this toxicity may be due at least in part to the unstable conjugated fatty acids, including cis-parinaric acid, contained within the seed. cis-Parinaric acid has been used for the measurement of phospholipase activity, lipase activity, and as an indicator of lipid peroxidation.{8577,8560,4746,1860}
Brand:CaymanSKU:71430 - 1 mgAvailable on backorder
cis-Parinaric acid is a naturally occurring polyunsaturated fatty acid containing an unusual conjugated (Z,E,E,Z) tetraene. This chromophore provides for a natural fluorescence at 432 nm with an excitation wavelength at 320 nm. cis-Parinaric acid occurs naturally in the seeds of the Makita tree, a tropical rainforest tree indigenous to Fiji. Makita seeds are inedible, and this toxicity may be due at least in part to the unstable conjugated fatty acids, including cis-parinaric acid, contained within the seed. cis-Parinaric acid has been used for the measurement of phospholipase activity, lipase activity, and as an indicator of lipid peroxidation.{8577,8560,4746,1860}
Brand:CaymanSKU:71430 - 500 µgAvailable on backorder
cis-Petroselinic acid is a monounsaturated fatty acid and isomer of oleic acid (Item No. 90260) that is a component of plant lipids.{39293} Arachidonic acid levels decrease, while linoleic acid levels increase, in the heart, liver, and blood of rats fed a diet containing petroselinic acid.{39294} It has been used in a composite membrane as a model of plant partitioning to study the uptake of hydrophobic organic contaminants and polycyclic aromatic hydrocarbons.{39293} It has also been used as a substrate for the synthesis of new sophorolipids, which could have biological activities similar to natural biosurfactants.{39292}
Brand:CaymanSKU:20024 -Available on backorder
cis-Petroselinic acid is a monounsaturated fatty acid and isomer of oleic acid (Item No. 90260) that is a component of plant lipids.{39293} Arachidonic acid levels decrease, while linoleic acid levels increase, in the heart, liver, and blood of rats fed a diet containing petroselinic acid.{39294} It has been used in a composite membrane as a model of plant partitioning to study the uptake of hydrophobic organic contaminants and polycyclic aromatic hydrocarbons.{39293} It has also been used as a substrate for the synthesis of new sophorolipids, which could have biological activities similar to natural biosurfactants.{39292}
Brand:CaymanSKU:20024 -Available on backorder
cis-Petroselinic acid is a monounsaturated fatty acid and isomer of oleic acid (Item No. 90260) that is a component of plant lipids.{39293} Arachidonic acid levels decrease, while linoleic acid levels increase, in the heart, liver, and blood of rats fed a diet containing petroselinic acid.{39294} It has been used in a composite membrane as a model of plant partitioning to study the uptake of hydrophobic organic contaminants and polycyclic aromatic hydrocarbons.{39293} It has also been used as a substrate for the synthesis of new sophorolipids, which could have biological activities similar to natural biosurfactants.{39292}
Brand:CaymanSKU:20024 -Available on backorder
cis-Petroselinic acid is a monounsaturated fatty acid and isomer of oleic acid (Item No. 90260) that is a component of plant lipids.{39293} Arachidonic acid levels decrease, while linoleic acid levels increase, in the heart, liver, and blood of rats fed a diet containing petroselinic acid.{39294} It has been used in a composite membrane as a model of plant partitioning to study the uptake of hydrophobic organic contaminants and polycyclic aromatic hydrocarbons.{39293} It has also been used as a substrate for the synthesis of new sophorolipids, which could have biological activities similar to natural biosurfactants.{39292}
Brand:CaymanSKU:20024 -Available on backorder
Resveratrol is a potent phenolic antioxidant found in grapes, red wine, and various berries that also has antiproliferative and anti-inflammatory activity.{9146} cis-Resveratrol is the double bond isomer of trans-resveratrol, the more often studied and naturally abundant of the two resveratrol isomers. cis-Resveratrol exhibits antioxidant activity in the µM range similar to that observed with trans-resveratrol.{15185} It blocks production of reactive oxygen species (ROS) by inhibition of NAD(P)H oxidase and also inhibits production of nitric oxide.{15185} At a concentration of 100 µM, cis-resveratrol significantly inhibits the expression of genes related to the Rel/NF-κB/IκB family, adhesion molecules, and acute-phase proteins in LPS and INF-γ-stimulated murine peritoneal macrophages.{15184} cis-Resveratrol inhibits uptake of noradrenaline and 5-HT by synaptosomes from rat brain with IC50 values of 79 and 51 µM, respectively.{15183} It also inhibits human monoamine oxidase-A (MOA-A) and MOA-B with IC50 values of 25 and 61 µM, respectively, which is similar to, but slightly less effective than, values obtained with trans-resveratrol.{15183}
Brand:CaymanSKU:10004235 - 10 mgAvailable on backorder
Resveratrol is a potent phenolic antioxidant found in grapes, red wine, and various berries that also has antiproliferative and anti-inflammatory activity.{9146} cis-Resveratrol is the double bond isomer of trans-resveratrol, the more often studied and naturally abundant of the two resveratrol isomers. cis-Resveratrol exhibits antioxidant activity in the µM range similar to that observed with trans-resveratrol.{15185} It blocks production of reactive oxygen species (ROS) by inhibition of NAD(P)H oxidase and also inhibits production of nitric oxide.{15185} At a concentration of 100 µM, cis-resveratrol significantly inhibits the expression of genes related to the Rel/NF-κB/IκB family, adhesion molecules, and acute-phase proteins in LPS and INF-γ-stimulated murine peritoneal macrophages.{15184} cis-Resveratrol inhibits uptake of noradrenaline and 5-HT by synaptosomes from rat brain with IC50 values of 79 and 51 µM, respectively.{15183} It also inhibits human monoamine oxidase-A (MOA-A) and MOA-B with IC50 values of 25 and 61 µM, respectively, which is similar to, but slightly less effective than, values obtained with trans-resveratrol.{15183}
Brand:CaymanSKU:10004235 - 100 mgAvailable on backorder
Resveratrol is a potent phenolic antioxidant found in grapes, red wine, and various berries that also has antiproliferative and anti-inflammatory activity.{9146} cis-Resveratrol is the double bond isomer of trans-resveratrol, the more often studied and naturally abundant of the two resveratrol isomers. cis-Resveratrol exhibits antioxidant activity in the µM range similar to that observed with trans-resveratrol.{15185} It blocks production of reactive oxygen species (ROS) by inhibition of NAD(P)H oxidase and also inhibits production of nitric oxide.{15185} At a concentration of 100 µM, cis-resveratrol significantly inhibits the expression of genes related to the Rel/NF-κB/IκB family, adhesion molecules, and acute-phase proteins in LPS and INF-γ-stimulated murine peritoneal macrophages.{15184} cis-Resveratrol inhibits uptake of noradrenaline and 5-HT by synaptosomes from rat brain with IC50 values of 79 and 51 µM, respectively.{15183} It also inhibits human monoamine oxidase-A (MOA-A) and MOA-B with IC50 values of 25 and 61 µM, respectively, which is similar to, but slightly less effective than, values obtained with trans-resveratrol.{15183}
Brand:CaymanSKU:10004235 - 5 mgAvailable on backorder
Resveratrol is a potent phenolic antioxidant found in grapes, red wine, and various berries that also has antiproliferative and anti-inflammatory activity.{9146} cis-Resveratrol is the double bond isomer of trans-resveratrol, the more often studied and naturally abundant of the two resveratrol isomers. cis-Resveratrol exhibits antioxidant activity in the µM range similar to that observed with trans-resveratrol.{15185} It blocks production of reactive oxygen species (ROS) by inhibition of NAD(P)H oxidase and also inhibits production of nitric oxide.{15185} At a concentration of 100 µM, cis-resveratrol significantly inhibits the expression of genes related to the Rel/NF-κB/IκB family, adhesion molecules, and acute-phase proteins in LPS and INF-γ-stimulated murine peritoneal macrophages.{15184} cis-Resveratrol inhibits uptake of noradrenaline and 5-HT by synaptosomes from rat brain with IC50 values of 79 and 51 µM, respectively.{15183} It also inhibits human monoamine oxidase-A (MOA-A) and MOA-B with IC50 values of 25 and 61 µM, respectively, which is similar to, but slightly less effective than, values obtained with trans-resveratrol.{15183}
Brand:CaymanSKU:10004235 - 50 mgAvailable on backorder
Resveratrol is a potent antioxidant found in grapes and red wine that also has anti-proliferative, anti-neoplastic and anti-angiogenic activities. In addition, resveratrol activates sirtuins{13296} and, in yeast, extends lifespan.{15280} cis-trismethoxy Resveratrol is a potent anti-mitotic drug that is 100-fold more active than resveratrol at inhibiting the growth of human colon cancer Caco-2 cells.{16948} It inhibits tubulin polymerization in a dose-dependent manner (IC50 = 4 μM) and inhibits enzymes involved in the synthesis of the polyamines, putrescine, and spermidine.{16948,16950} trans-trismethoxy Resveratrol has superior pharmacokinetic characteristics when compared with resveratrol, including greater plasma exposure, longer elimination half-life, and lower clearance.{16949}
Brand:CaymanSKU:- Resveratrol is a potent antioxidant found in grapes and red wine that also has anti-proliferative, anti-neoplastic and anti-angiogenic activities. In addition, resveratrol activates sirtuins{13296} and, in yeast, extends lifespan.{15280} cis-trismethoxy Resveratrol is a potent anti-mitotic drug that is 100-fold more active than resveratrol at inhibiting the growth of human colon cancer Caco-2 cells.{16948} It inhibits tubulin polymerization in a dose-dependent manner (IC50 = 4 μM) and inhibits enzymes involved in the synthesis of the polyamines, putrescine, and spermidine.{16948,16950} trans-trismethoxy Resveratrol has superior pharmacokinetic characteristics when compared with resveratrol, including greater plasma exposure, longer elimination half-life, and lower clearance.{16949}
Brand:CaymanSKU:- Resveratrol is a potent antioxidant found in grapes and red wine that also has anti-proliferative, anti-neoplastic and anti-angiogenic activities. In addition, resveratrol activates sirtuins{13296} and, in yeast, extends lifespan.{15280} cis-trismethoxy Resveratrol is a potent anti-mitotic drug that is 100-fold more active than resveratrol at inhibiting the growth of human colon cancer Caco-2 cells.{16948} It inhibits tubulin polymerization in a dose-dependent manner (IC50 = 4 μM) and inhibits enzymes involved in the synthesis of the polyamines, putrescine, and spermidine.{16948,16950} trans-trismethoxy Resveratrol has superior pharmacokinetic characteristics when compared with resveratrol, including greater plasma exposure, longer elimination half-life, and lower clearance.{16949}
Brand:CaymanSKU:- Resveratrol is a potent antioxidant found in grapes and red wine that also has anti-proliferative, anti-neoplastic and anti-angiogenic activities. In addition, resveratrol activates sirtuins{13296} and, in yeast, extends lifespan.{15280} cis-trismethoxy Resveratrol is a potent anti-mitotic drug that is 100-fold more active than resveratrol at inhibiting the growth of human colon cancer Caco-2 cells.{16948} It inhibits tubulin polymerization in a dose-dependent manner (IC50 = 4 μM) and inhibits enzymes involved in the synthesis of the polyamines, putrescine, and spermidine.{16948,16950} trans-trismethoxy Resveratrol has superior pharmacokinetic characteristics when compared with resveratrol, including greater plasma exposure, longer elimination half-life, and lower clearance.{16949}
Brand:CaymanSKU:-
cis-Vaccenic acid is an ω-7 fatty acid that has been found in mango pulp.{53557} It induces differentiation of, and γ-globin synthesis in, K562 and JK-1 cells, as well as isolated sickle cell transgenic mouse bone marrow erythroid progenitor cells (TMbmEPSCs).{33513}
Brand:CaymanSKU:20023 -Available on backorder
cis-Vaccenic acid is an ω-7 fatty acid that has been found in mango pulp.{53557} It induces differentiation of, and γ-globin synthesis in, K562 and JK-1 cells, as well as isolated sickle cell transgenic mouse bone marrow erythroid progenitor cells (TMbmEPSCs).{33513}
Brand:CaymanSKU:20023 -Available on backorder
cis-Vaccenic acid is an ω-7 fatty acid that has been found in mango pulp.{53557} It induces differentiation of, and γ-globin synthesis in, K562 and JK-1 cells, as well as isolated sickle cell transgenic mouse bone marrow erythroid progenitor cells (TMbmEPSCs).{33513}
Brand:CaymanSKU:20023 -Available on backorder
cis-Vaccenic acid is an ω-7 fatty acid that has been found in mango pulp.{53557} It induces differentiation of, and γ-globin synthesis in, K562 and JK-1 cells, as well as isolated sickle cell transgenic mouse bone marrow erythroid progenitor cells (TMbmEPSCs).{33513}
Brand:CaymanSKU:20023 -Available on backorder
cis-Vaccenic acid methyl ester is a methyl ester form of the monounsaturated fatty acid cis-vaccenic acid (Item No. 20023). It inhibits sodium influx in mouse brain synaptic plasma membranes, which is positively correlated with an increase in the disordering of membrane lipids.{39977} It has been used as an internal standard for the quantification of cis-vaccenic acid in A. mollis by LC-MS and in hempseed oil by GC-MS.{39978,39979}
Brand:CaymanSKU:20693 -Available on backorder
cis-Vaccenic acid methyl ester is a methyl ester form of the monounsaturated fatty acid cis-vaccenic acid (Item No. 20023). It inhibits sodium influx in mouse brain synaptic plasma membranes, which is positively correlated with an increase in the disordering of membrane lipids.{39977} It has been used as an internal standard for the quantification of cis-vaccenic acid in A. mollis by LC-MS and in hempseed oil by GC-MS.{39978,39979}
Brand:CaymanSKU:20693 -Available on backorder
Both prokaryotes and eukaryotes depend on small signalling molecules for cell-cell communication. cis-Δ2-11-methyl-Dodecenoic acid is a diffusible signal factor (DSF) in extracellular microbial and fungal communication systems.{13766} In a DSF bioassay, the minimum concentration of cis-Δ2-11-methyl-dodecenoic acid required for induction of a DSF biosensor was about 0.5 µM, which is 200-fold lower than that of the conformational isomer (trans-Δ2-11-methyl-dodecenoic acid) and 20,000-fold lower than that of the corresponding saturated fatty acid (11-methyl-dodecanoic acid).
Brand:CaymanSKU:10008123 - 1 mgAvailable on backorder
Both prokaryotes and eukaryotes depend on small signalling molecules for cell-cell communication. cis-Δ2-11-methyl-Dodecenoic acid is a diffusible signal factor (DSF) in extracellular microbial and fungal communication systems.{13766} In a DSF bioassay, the minimum concentration of cis-Δ2-11-methyl-dodecenoic acid required for induction of a DSF biosensor was about 0.5 µM, which is 200-fold lower than that of the conformational isomer (trans-Δ2-11-methyl-dodecenoic acid) and 20,000-fold lower than that of the corresponding saturated fatty acid (11-methyl-dodecanoic acid).
Brand:CaymanSKU:10008123 - 10 mgAvailable on backorder
Both prokaryotes and eukaryotes depend on small signalling molecules for cell-cell communication. cis-Δ2-11-methyl-Dodecenoic acid is a diffusible signal factor (DSF) in extracellular microbial and fungal communication systems.{13766} In a DSF bioassay, the minimum concentration of cis-Δ2-11-methyl-dodecenoic acid required for induction of a DSF biosensor was about 0.5 µM, which is 200-fold lower than that of the conformational isomer (trans-Δ2-11-methyl-dodecenoic acid) and 20,000-fold lower than that of the corresponding saturated fatty acid (11-methyl-dodecanoic acid).
Brand:CaymanSKU:10008123 - 5 mgAvailable on backorder
cis,cis-Octadeca-9,12-dienol, known less formally as linoleyl alcohol, is a polyunsaturated fatty alcohol produced by the reduction of linoleic acid (Item No. 90150). Conversely, it is oxidized in vivo to produce linoleic acid.{27076} cis,cis-Octadeca-9,12-dienol has been used to coat latex beads for phagocytosis assays and to synthesize a gallic acid ester for weight loss.{27075,27074} This alcohol of linoleic acid is also used in studies centering on the role of the carboxylic group of linoleic acid in enzyme recognition and cell signaling.{27077,27073}
Brand:CaymanSKU:-Out of stock
cis,cis-Octadeca-9,12-dienol, known less formally as linoleyl alcohol, is a polyunsaturated fatty alcohol produced by the reduction of linoleic acid (Item No. 90150). Conversely, it is oxidized in vivo to produce linoleic acid.{27076} cis,cis-Octadeca-9,12-dienol has been used to coat latex beads for phagocytosis assays and to synthesize a gallic acid ester for weight loss.{27075,27074} This alcohol of linoleic acid is also used in studies centering on the role of the carboxylic group of linoleic acid in enzyme recognition and cell signaling.{27077,27073}
Brand:CaymanSKU:-Out of stock
cis,cis-Octadeca-9,12-dienol, known less formally as linoleyl alcohol, is a polyunsaturated fatty alcohol produced by the reduction of linoleic acid (Item No. 90150). Conversely, it is oxidized in vivo to produce linoleic acid.{27076} cis,cis-Octadeca-9,12-dienol has been used to coat latex beads for phagocytosis assays and to synthesize a gallic acid ester for weight loss.{27075,27074} This alcohol of linoleic acid is also used in studies centering on the role of the carboxylic group of linoleic acid in enzyme recognition and cell signaling.{27077,27073}
Brand:CaymanSKU:-Out of stock
cis,cis-Octadeca-9,12-dienol, known less formally as linoleyl alcohol, is a polyunsaturated fatty alcohol produced by the reduction of linoleic acid (Item No. 90150). Conversely, it is oxidized in vivo to produce linoleic acid.{27076} cis,cis-Octadeca-9,12-dienol has been used to coat latex beads for phagocytosis assays and to synthesize a gallic acid ester for weight loss.{27075,27074} This alcohol of linoleic acid is also used in studies centering on the role of the carboxylic group of linoleic acid in enzyme recognition and cell signaling.{27077,27073}
Brand:CaymanSKU:-Out of stock
Cisapride is an agonist of serotonin (5-HT) receptor subtype 5-HT4 (IC50 = 0.483 μM in COS-7 cells expressing the human receptor).{34540} It induces relaxation of precontracted isolated rat esophageal thoracic muscularis mucosae preparations (EC50 = 102.33 nM). Cisapride (0.5 mg/kg) increases the rate of gastric emptying in rats. It is also a human ether-a-go-go related gene (hERG) channel blocker that binds to hERG channels with an IC50 value of less than 1 μM in a fluorescence polarization assay. Formulations containing cisapride have previously been used in the treatment of nocturnal heartburn associated with gastroesophageal reflux disease.
Brand:CaymanSKU:21657 -Out of stock
Cisapride is an agonist of serotonin (5-HT) receptor subtype 5-HT4 (IC50 = 0.483 μM in COS-7 cells expressing the human receptor).{34540} It induces relaxation of precontracted isolated rat esophageal thoracic muscularis mucosae preparations (EC50 = 102.33 nM). Cisapride (0.5 mg/kg) increases the rate of gastric emptying in rats. It is also a human ether-a-go-go related gene (hERG) channel blocker that binds to hERG channels with an IC50 value of less than 1 μM in a fluorescence polarization assay. Formulations containing cisapride have previously been used in the treatment of nocturnal heartburn associated with gastroesophageal reflux disease.
Brand:CaymanSKU:21657 -Out of stock
Cisapride is an agonist of serotonin (5-HT) receptor subtype 5-HT4 (IC50 = 0.483 μM in COS-7 cells expressing the human receptor).{34540} It induces relaxation of precontracted isolated rat esophageal thoracic muscularis mucosae preparations (EC50 = 102.33 nM). Cisapride (0.5 mg/kg) increases the rate of gastric emptying in rats. It is also a human ether-a-go-go related gene (hERG) channel blocker that binds to hERG channels with an IC50 value of less than 1 μM in a fluorescence polarization assay. Formulations containing cisapride have previously been used in the treatment of nocturnal heartburn associated with gastroesophageal reflux disease.
Brand:CaymanSKU:21657 -Out of stock
Cisapride is an agonist of serotonin (5-HT) receptor subtype 5-HT4 (IC50 = 0.483 μM in COS-7 cells expressing the human receptor).{34540} It induces relaxation of precontracted isolated rat esophageal thoracic muscularis mucosae preparations (EC50 = 102.33 nM). Cisapride (0.5 mg/kg) increases the rate of gastric emptying in rats. It is also a human ether-a-go-go related gene (hERG) channel blocker that binds to hERG channels with an IC50 value of less than 1 μM in a fluorescence polarization assay. Formulations containing cisapride have previously been used in the treatment of nocturnal heartburn associated with gastroesophageal reflux disease.
Brand:CaymanSKU:21657 -Out of stock
Cisatracurium is a competitive antagonist of nicotinic acetylcholine receptors (nAChRs) and non-depolarizing muscle relaxant.{43025,43024} It inhibits stimulation of human adult muscle nAChRs by acetylcholine (Item No. 23829) with an IC50 value of 10 nM.{43025} It also inhibits mouse nAChRs with IC50 values of 54 and 115 nM for adult and embryonic receptors, respectively.{43027} Cisatracurium increases apoptosis in HUVEC cells and decreases proliferation of HepG2 and HUVEC cells in vitro in a concentration-dependent manner.{43028,43029} It reduces the magnitude of electrically-evoked twitch tensions in isolated rat extensor digitorum longus and soleus sciatic nerve muscle preparations in a dose-dependent manner.{43024} Cisatracurium blocks electrically-evoked muscle twitches in anesthetized rabbits with an ED95 value of 0.04 mg/kg.{43026} Formulations containing cisatracurium have been used to facilitate intubation prior to surgery and as muscle relaxants.
Brand:CaymanSKU:22959 - 100 mgAvailable on backorder
Cisatracurium is a competitive antagonist of nicotinic acetylcholine receptors (nAChRs) and non-depolarizing muscle relaxant.{43025,43024} It inhibits stimulation of human adult muscle nAChRs by acetylcholine (Item No. 23829) with an IC50 value of 10 nM.{43025} It also inhibits mouse nAChRs with IC50 values of 54 and 115 nM for adult and embryonic receptors, respectively.{43027} Cisatracurium increases apoptosis in HUVEC cells and decreases proliferation of HepG2 and HUVEC cells in vitro in a concentration-dependent manner.{43028,43029} It reduces the magnitude of electrically-evoked twitch tensions in isolated rat extensor digitorum longus and soleus sciatic nerve muscle preparations in a dose-dependent manner.{43024} Cisatracurium blocks electrically-evoked muscle twitches in anesthetized rabbits with an ED95 value of 0.04 mg/kg.{43026} Formulations containing cisatracurium have been used to facilitate intubation prior to surgery and as muscle relaxants.
Brand:CaymanSKU:22959 - 25 mgAvailable on backorder
Cisatracurium is a competitive antagonist of nicotinic acetylcholine receptors (nAChRs) and non-depolarizing muscle relaxant.{43025,43024} It inhibits stimulation of human adult muscle nAChRs by acetylcholine (Item No. 23829) with an IC50 value of 10 nM.{43025} It also inhibits mouse nAChRs with IC50 values of 54 and 115 nM for adult and embryonic receptors, respectively.{43027} Cisatracurium increases apoptosis in HUVEC cells and decreases proliferation of HepG2 and HUVEC cells in vitro in a concentration-dependent manner.{43028,43029} It reduces the magnitude of electrically-evoked twitch tensions in isolated rat extensor digitorum longus and soleus sciatic nerve muscle preparations in a dose-dependent manner.{43024} Cisatracurium blocks electrically-evoked muscle twitches in anesthetized rabbits with an ED95 value of 0.04 mg/kg.{43026} Formulations containing cisatracurium have been used to facilitate intubation prior to surgery and as muscle relaxants.
Brand:CaymanSKU:22959 - 250 mgAvailable on backorder
Cisatracurium is a competitive antagonist of nicotinic acetylcholine receptors (nAChRs) and non-depolarizing muscle relaxant.{43025,43024} It inhibits stimulation of human adult muscle nAChRs by acetylcholine (Item No. 23829) with an IC50 value of 10 nM.{43025} It also inhibits mouse nAChRs with IC50 values of 54 and 115 nM for adult and embryonic receptors, respectively.{43027} Cisatracurium increases apoptosis in HUVEC cells and decreases proliferation of HepG2 and HUVEC cells in vitro in a concentration-dependent manner.{43028,43029} It reduces the magnitude of electrically-evoked twitch tensions in isolated rat extensor digitorum longus and soleus sciatic nerve muscle preparations in a dose-dependent manner.{43024} Cisatracurium blocks electrically-evoked muscle twitches in anesthetized rabbits with an ED95 value of 0.04 mg/kg.{43026} Formulations containing cisatracurium have been used to facilitate intubation prior to surgery and as muscle relaxants.
Brand:CaymanSKU:22959 - 50 mgAvailable on backorder
Cisplatin is a platinum-containing compound that acts as a DNA-crosslinking agent and interferes with replication and transcription, culminating in apoptosis.{25182} It forms intra- and interstrand crosslinks with DNA with intrastrand guanine-to-guanine or guanine-to-alanine links accounting for the majority of DNA binding.{39782} Cisplatin halts the cell cycle at the G2/M phase in vitro and is active against murine tumors transplanted into mice and in mouse xenograft models, including a reduction in tumor growth in a model of squamous cell carcinoma of the head and neck when administered at doses ranging from 7.5 to 12.5 mg/kg.{39783,39784} Cisplatin also inhibits the RecA recombinase of M. tuberculosis (IC50 = 2 µM), blocking protein splicing and cell growth.{26034} Formulations containing cisplatin have been used, alone and in combination therapy, in the treatment of a variety of cancers.
Brand:CaymanSKU:- Cisplatin is a platinum-containing compound that acts as a DNA-crosslinking agent and interferes with replication and transcription, culminating in apoptosis.{25182} It forms intra- and interstrand crosslinks with DNA with intrastrand guanine-to-guanine or guanine-to-alanine links accounting for the majority of DNA binding.{39782} Cisplatin halts the cell cycle at the G2/M phase in vitro and is active against murine tumors transplanted into mice and in mouse xenograft models, including a reduction in tumor growth in a model of squamous cell carcinoma of the head and neck when administered at doses ranging from 7.5 to 12.5 mg/kg.{39783,39784} Cisplatin also inhibits the RecA recombinase of M. tuberculosis (IC50 = 2 µM), blocking protein splicing and cell growth.{26034} Formulations containing cisplatin have been used, alone and in combination therapy, in the treatment of a variety of cancers.
Brand:CaymanSKU:- Cisplatin is a platinum-containing compound that acts as a DNA-crosslinking agent and interferes with replication and transcription, culminating in apoptosis.{25182} It forms intra- and interstrand crosslinks with DNA with intrastrand guanine-to-guanine or guanine-to-alanine links accounting for the majority of DNA binding.{39782} Cisplatin halts the cell cycle at the G2/M phase in vitro and is active against murine tumors transplanted into mice and in mouse xenograft models, including a reduction in tumor growth in a model of squamous cell carcinoma of the head and neck when administered at doses ranging from 7.5 to 12.5 mg/kg.{39783,39784} Cisplatin also inhibits the RecA recombinase of M. tuberculosis (IC50 = 2 µM), blocking protein splicing and cell growth.{26034} Formulations containing cisplatin have been used, alone and in combination therapy, in the treatment of a variety of cancers.
Brand:CaymanSKU:- Cisplatin is a platinum-containing compound that acts as a DNA-crosslinking agent and interferes with replication and transcription, culminating in apoptosis.{25182} It forms intra- and interstrand crosslinks with DNA with intrastrand guanine-to-guanine or guanine-to-alanine links accounting for the majority of DNA binding.{39782} Cisplatin halts the cell cycle at the G2/M phase in vitro and is active against murine tumors transplanted into mice and in mouse xenograft models, including a reduction in tumor growth in a model of squamous cell carcinoma of the head and neck when administered at doses ranging from 7.5 to 12.5 mg/kg.{39783,39784} Cisplatin also inhibits the RecA recombinase of M. tuberculosis (IC50 = 2 µM), blocking protein splicing and cell growth.{26034} Formulations containing cisplatin have been used, alone and in combination therapy, in the treatment of a variety of cancers.
Brand:CaymanSKU:-
Citalopram is a selective serotonin (5-HT) reuptake inhibitor (SSRI) with an IC50 value of 1.8 nM for 5-HT reuptake in rat brain synaptosomes.{38122} It is selective for 5-HT reuptake over that of dopamine and norepinephrine (IC50s = >6 mM). Citalopram potentiates headweaving and tremor induced by 5-hydroxy-L-tryptophan (Item No. 20539) in mice (ED50s = 0.61 and 0.66 mmol/kg, respectively). It also acts as an antagonist of nicotinic acetylcholine receptors (IC50 = 0.93 µM).{23021} Formulations containing citalopram have been used to treat depression. This product is also available as an analytical reference standard (Item No. 23252).
Brand:CaymanSKU:- Citalopram is a selective serotonin (5-HT) reuptake inhibitor (SSRI) with an IC50 value of 1.8 nM for 5-HT reuptake in rat brain synaptosomes.{38122} It is selective for 5-HT reuptake over that of dopamine and norepinephrine (IC50s = >6 mM). Citalopram potentiates headweaving and tremor induced by 5-hydroxy-L-tryptophan (Item No. 20539) in mice (ED50s = 0.61 and 0.66 mmol/kg, respectively). It also acts as an antagonist of nicotinic acetylcholine receptors (IC50 = 0.93 µM).{23021} Formulations containing citalopram have been used to treat depression. This product is also available as an analytical reference standard (Item No. 23252).
Brand:CaymanSKU:-