Immunogen: Recombinant human sPLA2 (Type V)

sPLA2 (human Type V) Monoclonal Antibody (Clone MCL-3G1) – 100 µg

Brand:
Cayman
Storage:

Phospholipase A2 (PLA2) catalyzes the hydrolysis of fatty acids at the sn-2 position of glycerophospholipids. PLA2 (type V) is a secretory PLA2 (sPLA2) of approximately 14 kDa and is one of the isoforms in the growing list of the PLA2 enzyme family.{3506} This enzyme, rather than the sPLA2 (type II), is responsible for arachidonic acid mobilization leading to prostaglandin production in macrophages and mast cells.{3941,4455,4053,8454} Consistent with this role, sPLA2 (type V) is associated with the golgi apparatus, nuclear envelope, and plasma membrane in murine bone marrow-derived mast cells.{7627} sPLA2 (type V) has been cloned from a variety of species including human, mouse, and rat.{7748,5754,7749} The enzyme is expressed in heart, lung, placenta, and spleen, as well as P388D1 macrophages and mast cells.{3941,4455,7749}  

 

Available on backorder

Add to quotes
SKU: 160510 - 100 µg Category:

Description

Immunogen: Recombinant human sPLA2 (Type V), W79A mutant • Host: Mouse • Species Reactivity: (+) Human • Cross Reactivity: (−) human sPLA2 (type IIa), cPLA2, iPLA2 • Applications: ELISA and WB • Isotype: IgG1 • Clone designation: MCL-3G1

Synonyms: gVPLA2|Secretory Phospholipase A2 (human Group V)

Immunogen: Recombinant human sPLA2 (Type V), W79A mutant

Formulation: 100 µg of protein A-purified antibody

Isotype: IgG1

Applications: ELISA and WB

Origin: Animal/Mouse

Stability: 365 days

Application|ELISA||Application|Immunohistochemistry||Application|Western Blot||Product Type|Antibodies|Monoclonal Antibodies||Research Area|Lipid Biochemistry|Glycerophospholipids|Phospholipases

Related products