S1P4 Polyclonal Antibody – 1 ea

Brand:
Cayman
Storage:

EDG-6 is a member of the endothelial differentiation gene (EDG) G protein-coupled receptor family and is a receptor for sphingosine 1-phosphate (S1P). Binding of S1P to EDG-6 activates Erk, leading to the activation of the transcription factor Elk1 and thus the mitogen-activated protein kinase (MAPK) signal transduction pathway. The protein is specifically expressed in fetal and adult lymphoid and hematopoietic tissue as well as in lung. Human EDG-6 gene is intronless and is mapped to chromosome 19p13.3 at the D19S120 marker.  

 

Available on backorder

SKU: 13489 - 1 ea Category:

Description

Antigen: synthetic peptide from human S1P4 wihin the region of amino acids 1-50 • Host: rabbit • Cross Reactivity: (+) human and mouse S1P4 • Application(s): ICC, IF, and WB • Binding of S1P to S1P4 activates Erk, leading to the activation of the transcription factor Elk1 and thus the MAPK signal transduction pathway.


Synonyms: EDG-6|S1PR4|Sphingosine-1-phosphate Receptor 4

Immunogen: synthetic peptide from human S1P4 within the region of amino acids 1-50

Formulation: 100 µg of peptide affinity-purified IgG in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide.

Isotype:

Applications: WB, IF, and ICC

Origin: Animal/Rabbit

Stability: 365 days


Application|Immunocytochemistry||Application|Immunofluorescence||Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Immunology & Inflammation|Adaptive Immunity||Research Area|Immunology & Inflammation|Innate Immunity