This EIA so called Easy Sampling EIA kit works with any sample collected on any kind of protease inhibitors, without extraction but a simple dilution. Ghrelin discovered in 1999, is fast becoming an endocrinology target of the millennium. Ghrelin, identified in rat stomach as an endogenous ligand for the GH secretagogue receptor, is mainly produced in stomach, but has been demonstrated in many other organs. In addition to GH-releasing properties and its orexant action, Ghrelin could act as an hormone having effects on gastric motility (similarity with the peptide hormone motilin), acidic secretion, cardiovascular action, antiproliferative effects, pancreatic and glucose metabolism function, sleep… Ghrelin gene raises to mRNA prepro-ghrelin of 117 amino acids. This precursor is processed into Ghrelin, 28 amino acids (human). Before being secreted, this peptide is octanoylated at Ser 3 by GOAT (Ghrelin Octanoyl Acyl Transferase). This step is essential for biological activity making GOAT a perfect target for drugs in feeding behaviour. Interestingly, the potential therapeutic importance of this hormone is not restricted to regulation of food intake but also in cachexia (related to cancer treatment, anorexia nervosa or ischemia) gastric motility and may be involved in osteoporosis, somatopause, infertility and ovulation induction, neurological disorders (Alcoholism, Post Traumatic Stress disorders…) and cardiovascular diseases. [Bertin Catalog No. A05317.96 wells]
Available on backorder
Formulation:
Formal name:
Synonyms: Acylated Ghrelin (mouse, rat) Easy Sampling ELISA
Host:
Imunogen:
Applications:
Clone:
Purity:
Origin:
Application|ELISA||Product Type|Assay Kits|ELISA||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Obesity||Research Area|Neuroscience|Behavioral Neuroscience|Addiction Research||Research Area|Neuroscience|Neuroendocrinology
For the quantitation of Human LCN2 concentrations in cell culture supernates, serum, plasma(heparin), saliva and urine.
Available on backorder
For the quantitation of Human CSF3 concentrations in cell culture supernates, serum and plasma (heparin, EDTA, citrate).
Available on backorder
For the quantitation of Mouse Ifng concentrations in bone tissue, cell culture supernates and serum.
Available on backorder
