Immunogen: A trimethyl-peptide corresponding to trimethyl-histone H3 (Lys4) • Host: Rabbit • Species Reactivity: (+) Vertebrates • Cross Reactivity: (+) Histone H3 trimethylated at lysine 4 (K4me3); (-) Monomethylated lysine 4 (K4me1)

Trimethyl Histone H3 (Lys4) Monoclonal Antibody (Clone RM137) – 100 µg

Brand:
Cayman
Storage:

Histone H3 undergoes many modifications including acetylation, methylation, and phosphorylation that are important for regulation of gene transcription. Methylation at lysine 4 of histone 3 (H3K4) is an evolutionarily conserved modification associated with transcriptionally active chromatin. The SET1/MLL (KMT2) family of methyltransferases is the principal enzyme family responsible for H3K4 methylations. This antibody reacts to histone H3 trimethylated at lysine 4 (K4me3) and does not detect monomethylated lysine 4 (K4me1), dimethylated lysine 4 (K4me2), or other methylations in histone H3.  

 

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SKU: 20718 - 100 µg Category:

Description

Immunogen: A trimethyl-peptide corresponding to trimethyl-histone H3 (Lys4) • Host: Rabbit • Species Reactivity: (+) Vertebrates • Cross Reactivity: (+) Histone H3 trimethylated at lysine 4 (K4me3); (-) Monomethylated lysine 4 (K4me1), dimethylated lysine 4 (K4me2), other methylations in histone H3 • Applications: ELISA, multiplex-based assays, WB

Synonyms:

Immunogen: A trimethyl-peptide corresponding to trimethyl-histone H3 (Lys4)

Formulation: 100 μg of protein A-affinity purified antibody from an animal origin free culture supernatant

Isotype: IgG

Applications: ELISA, multiplex-based assays, WB

Origin:

Stability: 365 days

Application|ELISA||Application|Multiplex||Application|Western Blot||Product Type|Antibodies|Monoclonal Antibodies||Research Area|Epigenetics, Transcription, & Translation|Histones/Histone Peptides|Methylated||Research Area|Epigenetics, Transcription, & Translation|Writers|Histone Methylation

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