Immunogen: Synthetic peptide from the C-terminal region of human TP • Host: Rabbit • Species Reactivity: (+) Human

TP Receptor (human) Polyclonal FITC Antibody – 1 ea

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Cayman
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Thromboxane A2 (TXA2) is a potent vasoconstrictor and activator of platelet aggregation. The short half-life of TXA2 ensures local action whether generated by vascular endothelial cells or by platelets and confers physiologically beneficial or deleterious effects under inflammatory situations.{146,11131} TXA2 elicits its effects via a 7-transmembrane domain G protein-coupled receptor, the TP receptor.{6062} This receptor can also bind prostaglandin H2 and isoprostanes and was first cloned from human placenta and the platelet-like MEG-01 cell line.{11146,7729} The TP receptor is highly expressed in platelets and is relatively less abundant in tissues such as lung, kidney, brain, spleen, thymus, monocytes, uterus, and placenta.{3167,11368,2061,4311,8380,7235}  

 

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SKU: 10012559 - 1 ea Category:

Description

Immunogen: Synthetic peptide from the C-terminal region of human TP • Host: Rabbit • Species Reactivity: (+) Human, African green monkey, mouse, and rat • Application: FC • The TP receptor is a GPCR that mediates the action of TXA2.

Synonyms: Thromboxane A2 Receptor|TXA2 Receptor

Immunogen: Synthetic peptide from the C-terminal region of human TP receptor

Formulation: 500 µl of fluorescein-labeled, peptide affinity-purified antibody

Isotype:

Applications: FC

Origin: Animal/Rabbit

Stability: 365 days

Application|Flow Cytometry||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Cardiovascular System|Blood||Research Area|Immunology & Inflammation|Innate Immunity||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway

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