Immunogen: Recombinant mouse sEH • Host: Rabbit • Species Reactivity: (+) Human and mouse • Cross Reactivity: other species not tested • Applications: WB • MW = 64 kDa

Soluble Epoxide Hydrolase (FL) Polyclonal Antibody – 500 µl

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Cayman
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Soluble epoxide hydrolase (sEH) is a member of the α/β-hydrolase fold enzyme family that catalyzes the hydrolysis of bioactive fatty acid epoxides to inactive vicinal diols.{52737} It is a homodimer in which each subunit is composed of two domains, a C-terminal epoxide hydrolase domain and an N-terminal phosphatase domain.{52738,15765} sEH is localized to the cytoplasm or to peroxisomes in a tissue specific manner and is found in various tissues, including skin, lung, uterus, kidney, brain, and myocardium.{52740,52739} sEH is also expressed in the vasculature and inhibition of sEH attenuates pathogenic vascular remodeling and hypertension via preservation of cardioprotective epoxyeicosatrienoic acids (EETs) in rat models of atherosclerosis and hypertension, respectively.{52741} Inhibition of sEH also has a protective role in various diseases including inflammatory bowel disease, osteoarthritis, seizure, stroke, and Alzheimer’s disease, as well as in various chronic pain states.{52737,50771} Cayman’s Soluble Epoxide Hydrolase (FL) Polyclonal Antibody can be used for Western blot applications. The antibody recognizes sEH at 64 kDa from human and murine samples.  

 

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SKU: 13560 - 500 µl Category:

Description

Immunogen: Recombinant mouse sEH • Host: Rabbit • Species Reactivity: (+) Human and mouse • Cross Reactivity: other species not tested • Applications: WB • MW = 64 kDa

Synonyms: Cytosolic Epoxide Hydrolase (CEH)|EPHX2|Epoxide Hydrolase 2|sEH

Immunogen: Recombinant mouse sEH

Formulation: 100 μg of Protein A-purified antibody

Isotype:

Applications: WB

Origin: Animal/Rabbit

Stability: 365 days

Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Cardiovascular System|Cardiovascular Diseases|Hypertension||Research Area|Immunology & Inflammation||Research Area|Neuroscience|Neurodegenerative Disorders|Alzheimer’s Disease

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