SMAD7 Polyclonal Antibody – 100 µg

Brand:
Cayman
Storage:

SMADs are a family of intracellular proteins that are essential components in the signaling pathways of the serine/threonine kinase receptors of the transforming growth factor β superfamily.{19268} SMADs can be divided into receptor-regulated SMADs (R-SMADs: SMAD1, SMAD2, SMAD3, SMAD5, SMAD8, and SMAD9), common-mediator SMAD (co-SMAD: SMAD4), and inhibitory SMADs (I-SMADs: SMAD6 and SMAD7). SMAD1, SMAD5, SMAD8, and SMAD9 have high degrees of homology and antibodies are available that recognize sequences common to all of them. SMAD8 and SMAD9 are typically used as alternate names for one another in the literature.  

 

Available on backorder

SKU: 10845 - 100 µg Category:

Description

Antigen: synthetic peptides corresponding to amino acids 12-29 and 36-50 of human SMAD7 • Host: rabbit • Cross Reactivity: (+) human, mouse, rat, and ovine SMAD7; predicted to react with chimpanzee, canine, pufferfish, Xenopus, and zebrafish SMAD7 • Application(s): WB • SMAD7 is an inhibitory SMAD (I-SMAD) that is part of a family of intracellular proteins that are essential components in the signaling pathways of the serine/threonine kinase receptors of the transforming growth factor β superfamily.


Synonyms:

Immunogen: synthetic peptides corresponding to amino acids 12-29 and 36-50 of human SMAD7

Formulation: 100 µg of protein G-purified IgG in 200 µl PBS with 0.05% sodium azide

Isotype:

Applications: WB

Origin: Animal/Rabbit

Stability: 180 days


Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Cell Biology|Cell Signaling