Description
SMADs are a family of intracellular proteins that are essential components in the signaling pathways of the serine/threonine kinase receptors of the transforming growth factor β superfamily.{19294} SMADs can be divided into receptor-regulated SMADs (R-SMADs: SMAD1, SMAD2, SMAD3, SMAD5, SMAD8, and SMAD9), common-mediator SMAD (co-SMAD: SMAD4), and inhibitory SMADs (I-SMADs: SMAD6 and SMAD7). SMAD1, SMAD5, SMAD8, and SMAD9 have high degrees of homology and antibodies are available that recognize sequences common to all of them. SMAD8 and SMAD9 are typically used as alternate names for one another in the literature.
Synonyms:
Immunogen: synthetic peptides corresponding to amino acids 186-199 and 509-523 of human SMAD4
Formulation: 100 µg of protein G-purified IgG in 200 µl PBS containing 0.2% gelatin and 0.05% sodium azide
Isotype:
Applications: WB
Origin: Animal/Rabbit
Stability: 180 days
Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Cell Biology|Cell Signaling
