Description
Hepsin is a type II membrane-associated protein that has an extracellular proteolytic domain and exhibits low sequence homology to other known proteases.{9602,9603} Hepsin overexpression is observed in prostate, breast, kidney, and ovarian cancers and due to low homology to other known proteases may provide a unique target for pharmacological therapy.{9067,9600,9601,9599,9604} Hepsin is necessary for cell growth in vitro and may play a role in metastatic expansion by factor VII activation.{9598,9606,9599} Cayman Chemical’s hepsin polyclonal antibody can be used for WB and IHC (formalin-fixed paraffin-embedded tissue) analysis for hepsin on samples of human origin. Other applications for use of this antibody have not yet been tested.
Synonyms:
Immunogen: Synthetic peptide from the internal region of human hepsin
Formulation: Peptide affinity-purified polyclonal antibody lyophilized from 500 µl
Isotype:
Applications: IHC (formalin-fixed paraffin-embedded tissue) and WB
Origin: Animal/Rabbit
Stability: 365 days
Application|Immunohistochemistry||Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Cancer
