Cayman’s PGE2 ELISA is a sensitive competitive assay that uses a high-affinity PGE2 monoclonal antibody for quantification of PGE2 in plasma

Prostaglandin E2 ELISA Kit – Monoclonal – 480 solid wells

Brand:
Cayman
Storage:
-20

Prostaglandin E2 (PGE2) is a primary product of arachidonic acid metabolism in many cells. Like most eicosanoids, it does not exist preformed in any cellular reservoir. When cells are activated or exogenous free arachidonate is supplied, PGE2 is synthesized de novo and released into the extracellular space. In vivo, PGE2 is rapidly converted to an inactive metabolite (13,14-dihydro-15-keto PGE2) by the prostaglandin 15-dehydrogenase pathway.{581,182} The half-life of PGE2 in the circulatory system is approximately 30 seconds and normal plasma levels are 3-12 pg/ml.{366} Our PGE2 ELISA has been validated for use with urine, plasma, and culture media samples. In general, urine and culture media samples can be diluted, if necessary, and added directly to the assay well. Plasma samples should be purified prior to use. Because of the rapid metabolism of PGE2, the determination of in vivo PGE2 biosynthesis is often best accomplished by the measurement of PGE2 metabolites. Our Prostaglandin E Metabolite assay (Item No. 514531) converts all major PGE2 metabolites into a single stable derivative which is easily measurable by ELISA.  

 

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SKU: 514010 - 480 solid wells Category:

Description

Cayman’s PGE2 ELISA is a sensitive competitive assay that uses a high-affinity PGE2 monoclonal antibody for quantification of PGE2 in plasma, urine, and culture media samples.

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Synonyms:  PGE2 EIA Kit – Monoclonal

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Origin: Animal/Goat|Animal/Mouse|Animal/Eel|Animal/Bovine

Application|ELISA||Product Type|Assay Kits|ELISA||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Prostaglandins||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway

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