Host: rat • Cross Reactivity: (+) human podoplanin (Clone NZ-1.2) • Application(s): FC and WB • Podoplanin is expressed in many tumors and many normal cells

Podoplanin Monoclonal Antibody (Clone NZ-1.2) – 1 ea

Brand:
Cayman
Storage:

Podoplanin is a mucin type-1 glycoprotein of 40-43. Podoplanin is expressed in many tumors and many normal cells, especially lymphatic epithelial cells and follicular DCs. It appears to serve as a ligand for CLEC-2. Podoplanin expression is positively correlated with tumors expressing greater invasive and metastatic potential. Podoplanin is directly involved in cell migration, aids metastases formation and tumor cell invasion of tissue.{19761,19762,19763} It has also been determined that podoplanin expression is induced through Src activation of Cas.{19760} Recently there are indications of podoplanin presence on Th17 cells.{19759} Initial studies below indicate the presence of podoplanin on a small but distinct population of CD4+ cells from human PBMC.  

 

Available on backorder

Add to quotes
SKU: 11004 - 1 ea Category:

Description

Host: rat • Cross Reactivity: (+) human podoplanin (Clone NZ-1.2) • Application(s): FC and WB • Podoplanin is expressed in many tumors and many normal cells, especially lymphatic epithelial cells and follicular DC. Expression is positively correlated with tumors expressing greater invasive and metastatic potential. Podoplanin is directly involved in cell migration, aids metastases formation and tumor cell invasion of tissue.

Synonyms: Aggrus|gp38|T1A

Immunogen:

Formulation: 100 µg of protein G-purified IgG in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide

Isotype:

Applications: FC and WB

Origin: Animal/Rat

Stability: 180 days

Application|Flow Cytometry||Application|Western Blot||Product Type|Antibodies|Monoclonal Antibodies||Research Area|Cancer|Cell Migration & Metastasis||Research Area|Immunology & Inflammation|Adaptive Immunity||Research Area|Immunology & Inflammation|Innate Immunity

Related products