Antigen: human full length p38 MAPK • Host: mouse

p38 MAPK Monoclonal Antibody (Clone 9F12) – 1 ea

Brand:
Cayman
Storage:

p38 mitogen-activated protein kinase (MAPK) is a member of the serine-threonine MAPK family that triggers many cellular processes including cell cycle, development, and apoptosis.{15420,15421} These kinases are activated by environmental stress signals such as osmotic shock, infection, and cytokines causing phosphorylation of p38 MAPK. This results in a phosphorylation cascade, activating transcription factors, and inducing gene expression.{15420,15424} p38 MAPK is widely expressed in heart, brain, skeletal muscle, platelets, and immune cells. Due to this distribution, p38 MAPK plays a role in cardiovascular disease, arthritis, and cancer.{15421,15422,1523,15424} It is mainly present in the cytosol, but can also be found in the nucleus after activation.{15421} Based on the amino acid sequence, the expected molecular weight of this protein is 41 kDa.  

 

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SKU: 10011301 - 1 ea Category:

Description

Antigen: human full length p38 MAPK • Host: mouse, clone 9F12 • Cross Reactivity: (+) human, mouse, and rat p38 MAPK • Application(s): FC, ICC, and WB • p38 MAPK is a member of the serine-threonine MAPK family that triggers many cellular processes including cell cycle, development, and apoptosis.

Synonyms: p38 MAP Kinase|p38 MAPKα|p38 Mitogen-activated Protein Kinase

Immunogen: human full length p38 MAPK

Formulation: 200 µg IgG1 in 500 µl PBS, pH 7.4, containing 50% glycerol, 0.5 mg/ml BSA, and 0.02% sodium azide

Isotype:

Applications: WB, ICC, and flow cytometry

Origin: Animal/Mouse

Stability: 365 days

Application|Flow Cytometry||Application|Immunocytochemistry||Application|Western Blot||Product Type|Antibodies|Monoclonal Antibodies||Research Area|Cancer|Cell Signaling|p38 MAPK Signaling||Research Area|Cardiovascular System|Cardiovascular Diseases||Research Area|Cardiovascular System|Heart||Research Area|Cell Biology|Cell Cycle||Research Area|Cell Biology|Cell Death|Apoptosis||Research Area|Cell Biology|Cell Signaling|p38 MAPK Signaling||Research Area|Immunology & Inflammation|Autoimmunity|Rheumatoid Arthritis||Research Area|Infectious Disease

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