Antigen: recombinant human Nampt • Host: mouse

Nampt Monoclonal Antibody (Clone OMNI 379) – 100 µg

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Cayman
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Nampt is a 52 kDa adipokine secreted by adipose tissue that is involved in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Two forms of Nampt exist, an intracellular form (iNampt) and an extracellular form (eNampt). While the function of iNampt as an essential and rate-limiting NAD+ biosynthetic enzyme is well established, the physiological role of eNampt is still a matter of debate. Nampt has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates the insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.  

 

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SKU: 10813 - 100 µg Category:

Description

Antigen: recombinant human Nampt • Host: mouse, clone OMNI 379 • Cross Reactivity: (+) human, mouse, and rat Nampt • Application(s): ELISA, FC, ICC, IHC, IP, and WB • Nampt is an adipokine involved in the biosynthesis of NAD+ and is highly expressed in visceral fat. It promotes vascular smooth muscle cell maturation, inhibits neutrophil apoptosis, and activates the insulin receptor with insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. Serum levels of Nampt correlate with obesity.

Synonyms: Nicotinamide Phosphoribosyltransferase|PBEF1|Pre-B Cell Colony Enhancing Factor 1|Visfatin

Immunogen: recombinant human Nampt

Formulation: A 1 mg/ml solution in PBS, pH 7.4

Isotype: IgG2aκ

Applications: ELISA, FC, ICC, IHC, IP, and WB

Origin: Animal/Mouse

Stability: 180 days

Application|ELISA||Application|Flow Cytometry||Application|Immunocytochemistry||Application|Immunohistochemistry||Application|Immunoprecipitation||Application|Western Blot||Product Type|Antibodies|Monoclonal Antibodies||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Obesity

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