Methylated Lysine Polyclonal Antibody – 100 µg

Brand:
Cayman
Storage:

Immunogen: Methylated KLH conjugated • Host: Rabbit • Cross Reactivity: (+) Mono- and di-methylated lysine residues in multiple species (cross-reactivity with tri-methyl lysine has not been tested); (−) Acetylated lysine • Application: ELISA, IHC, IP, and WB • Lysine can be methylated once, twice, or three times by lysine methyltransferases. The transfer of methyl groups from SAM to histones is catalyzed by histone methyltransferases.  

 

SKU: 31686- 100 µg Category:

Description

Post-translational modifications of proteins play critical roles in the regulation and function of many known biological processes. Proteins can be post-translationally modified in many different ways, and a common post-transcriptional modification of lysine involves methylation.{17715} Lysine can be methylated once, twice, or three times by lysine methyltransferases. The transfer of methyl groups from S-adenosyl methionine to histones is catalyzed by enzymes known as histone methyltransferases. Histones which are methylated on certain residues can act epigenetically to repress or activate gene expression.{17715,17725}


Synonyms:

Immunogen: Methylated KLH

Formulation: 100 µg (1 mg/ml) of affinity-purified polyclonal antibody

Isotype: IgG

Applications: ELISA, IHC, IP, WB

Origin: Animal/Rabbit

Stability: 365 days


Application|ELISA||Application|Immunohistochemistry||Application|Immunoprecipitation||Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Epigenetics, Transcription, & Translation|Erasers|DNA/RNA Demethylation||Research Area|Epigenetics, Transcription, & Translation|Histones/Histone Peptides|Methylated||Research Area|Epigenetics, Transcription, & Translation|Writers|DNA/RNA Methylation