LSD1 Polyclonal Antibody (aa 100-150) – 1 ea

Brand:
Cayman
Storage:

LSD1 is a flavin-containing nuclear protein having a N-terminal SWIRM domain, a C-terminal FAD-binding motif, and an amine oxidase domain. It functions as a transcriptional corepressor and catalyzes the flavin-dependent demethylation of Lys4 of histone 3 resulting in the formation of methyl-free lysine and release of formaldehyde. LSD1 has been found to be typically associated with CoREST and histone deacetylases 1 and 4 and participates in the silencing of endogenous neuron-specific genes.  

 

Available on backorder

SKU: 13554 - 1 ea Category:

Description

Antigen: peptide corresponding to a portion of human LSD1 amino acids 100-150 • Host: rabbit • Cross Reactivity: (+) canine, human, mouse, rat, Rhesus monkey, and zebrafish LSD1 • Application(s): WB • LSD1 functions as a transcriptional corepressor and catalyzes the flavin-dependent demethylation of Lys4 of histone 3 resulting in the formation of methyl-free lysine and release of formaldehyde. It is typically associated with CoREST and HDACs 1 and 4 and participates in the silencing of endogenous neuron-specific genes.


Synonyms: Amine Oxidase (flavin containing) Domain 2

Immunogen: peptide corresponding to a portion of human LSD1 amino acids 100-150

Formulation: 100 µg of peptide affinity-purified IgG in 200 µl PBS containing 0.2% gelatin and 0.05% sodium azide

Isotype:

Applications: WB

Origin: Animal/Rabbit

Stability: 365 days


Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Epigenetics, Transcription, & Translation|Erasers|Histone Demethylation