Description
Lecithin:cholesterol acyltransferase (LCAT) has both phospholipase and acyltransferase activities. LCAT catalyzes the fatty acid transfer from the sn-2 position of phosphatidylcholine (lecithin) to cholesterol and to a lesser degree to other acceptor molecules.{14521,14519} This enzyme is critical to the process of reverse cholesterol transport or movement of cholesterol esters into high density lipoprotein (HDL) particles from cells.{13279} LCAT is abundant in blood-plasma, however it is present in other fluids and tissues such as ovary. This protein may be detected on immunoblot at 49.5 kDa as well as at 66 kDa when fully glycosylated.{14522,14520} Plasma samples should be diluted prior to electrophoresis and immunoblotting to avoid the band-broadening effect caused by comigration with endogenous albumin.
Synonyms: Lecithin:Cholesterol Acyltransferase|Phosphatidylcholine-Sterol O-Acyltransferase
Immunogen: Synthtic peptide from an internal region of human LCAT
Formulation: 500 μl of peptide affinity-purified antibody
Isotype:
Applications: WB; other applications not tested
Origin: Animal/Rabbit
Stability: 365 days
Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Cardiovascular System|Blood|Acute Phase Reactants||Research Area|Cardiovascular System|Blood|Serum Proteins||Research Area|Cardiovascular System|Lipids & Lipoproteins|Lipoproteins||Research Area|Cardiovascular System|Lipids & Lipoproteins|Storage & Transport||Research Area|Endocrinology & Metabolism|Reproductive Biology||Research Area|Lipid Biochemistry|Glycerophospholipids|Acyltransferases||Research Area|Lipid Biochemistry|Glycerophospholipids|Phospholipases||Research Area|Lipid Biochemistry|Lipid Transport||Research Area|Lipid Biochemistry|Sterol Lipids
