Description
Jumonji AT rich interactive domain 1B (JARID1B) nuclear proteins are potential histone demethylases.{23558,23562} JARID1B demethylation of Lys-4 of histone H3 plays an important role in breast cancer cell proliferation through BRCA1 repression.{23558} JARID1B acts as a transcriptional co-repressor of two developmental transcription factors, PAX-9 and BF1, which are crucial for organogenesis in mouse embryo.{23560} JARID1B has also been shown to interact directly with histone deacetylase.{23559}
Synonyms: CT31|Jumonji/ARID domain-containing protein 1B|KDM5B|Lysine-specific Demethylase 5B|RBBP2H1
Immunogen: Synthetic peptide from the C-terminal region of human JARID1B/PLU1
Formulation: Peptide affinity-purified polyclonal antibody
Isotype:
Applications: FC and ICC
Origin:
Stability: 730 days
Application|Flow Cytometry||Application|Immunocytochemistry||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Epigenetics, Transcription, & Translation|Erasers|Histone Deacetylation||Research Area|Epigenetics, Transcription, & Translation|Erasers|Histone Demethylation||Research Area|Epigenetics, Transcription, & Translation|Transcription Factors
