Cayman’s IL-1β (human) ELISA is an immunometric (i.e.

Interleukin-1β (human) ELISA Kit – 480 wells

Brand:
Cayman
Storage:
-20

Interleukin 1 (IL-1) is a name for a family of proteins which includes IL-1α, IL-1β, ILra (Interleukin receptor antagonist) and IL-18. IL-1β is synthesized as 269 amino acid pro-cytokine that is enzymatically cleaved by IL-1β-converting enzyme (ICE) into the active 154 amino acid, 17 kDa peptide mature peptide.{10662,1643} IL-1β is produced by many cell types including macrophages, monocytes, astrocytes, endothelial cells, smooth muscle cells, keratinocytes, adipocytes, T cells, and eosinophils.{7221} Although IL-1α and IL-1β exhibit only 26% amino acid identity,{10662} they bind to the same cell-surface receptors, IL-1 RI and IL-1 RII, present on a variety of cell types involved in immune or inflammatory responses.{10660,10775,10668} Normal production of IL-1 is critical for mediating host responses to infection and injury.{1643,7221} Disease states in which IL-1 actively participates include inflammatory diseases, such as arthritis, inflammatory bowel disease, and shock, as well as arteriosclerosis, allergic disease, and some types of cancer.{7221,11054}  

 

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SKU: 583311 - 480 wells Category:

Description

Cayman’s IL-1β (human) ELISA is an immunometric (i.e., sandwich) ELISA that permits IL-1β measurements within the range of 3.9-250 pg/ml, typically with a limit of detection of 3.9 pg/ml.

Formulation:

Formal name:

Synonyms:  IL-1β (human) EIA Kit

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Imunogen:

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Origin: Animal/Mouse|Animal/Bovine

Application|ELISA||Product Type|Assay Kits|ELISA||Research Area|Immunology & Inflammation|Adaptive Immunity||Research Area|Immunology & Inflammation|Allergy||Research Area|Immunology & Inflammation|Autoimmunity|Rheumatoid Arthritis||Research Area|Immunology & Inflammation|Innate Immunity|Sepsis/Shock

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