Cayman’s IL-1α (human) ELISA is an immunometric (i.e.

Interleukin-1α (human) ELISA Kit – 480 wells

Brand:
Cayman
Storage:
-20

Interleukin-1 (IL-1) is a name for a family of proteins which include IL-α, IL-1β, ILra (interleukin receptor antagonist), and IL-18. IL-1α is synthesized as a 33 kDa (271 amino acid) pro-cytokine that is enzymatically cleaved by calpain into the active 159 amino acid, 17 kDa peptide.{10662,10661,10667} IL-1α is produced by many cells types including macrophages, monocytes, astrocytes, keratinocytes, adipocytes, T-cells, and eosinophils.{866} Although IL-1α and IL-1β exhibit only 26% amino acid identity,{10662} they bind to the same cell-surface receptors, IL-1 RI and IL-1 RII, present on a variety of cell types involved in immune or inflammatory responses.{10660,10775,10668} Normal production of IL-1 is critical for mediating host responses to infection and injury.{7221,11054} Disease states in which IL-1 actively participates include inflammatory diseases such as arthritis, inflammatory bowel disease, and shock, as well as atherosclerosis, allergy, and some types of cancer.{7221,11054} Cayman’s IL-1α (human) ELISA Kit is an immunometric (i.e., sandwich) ELISA that permits IL-1α measurements within the range of 3.9-250 pg/ml, typically with a limit of detection of 3.9 pg/ml.  

 

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SKU: 583301 - 480 wells Category:

Description

Cayman’s IL-1α (human) ELISA is an immunometric (i.e., sandwich) ELISA that permits IL-1α measurements within the range of 3.9-250 pg/ml, typically with a limit of detection of 3.9 pg/ml.

Formulation:

Formal name:

Synonyms:  IL-1α (human) EIA Kit

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Imunogen:

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Origin: Animal/Bovine|Animal/Mouse

Application|ELISA||Product Type|Assay Kits|ELISA||Research Area|Immunology & Inflammation|Adaptive Immunity||Research Area|Immunology & Inflammation|Allergy||Research Area|Immunology & Inflammation|Autoimmunity|Rheumatoid Arthritis||Research Area|Immunology & Inflammation|Gastric Disease||Research Area|Immunology & Inflammation|Innate Immunity|Sepsis/Shock

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