Immunogen: Peptide corresponding to H4S1Ph • Host: Rabbit • Species Reactivity: (+) Vertebrates • Cross Reactivity: (+) H4S1Ph

Histone H4S1Ph Monoclonal Antibody – 100 µg

Brand:
Cayman
Storage:

Histone H4 is one of four core histone proteins that are involved in the organization of DNA into chromatin.{18136} Histones are globular proteins with unstructured N-terminal tails and are subject to a variety of post-translational modifications, such as methylation, acetylation, phosphorylation, and citrullination, that can influence chromatin structure and regulate gene transcription.{18136,57056} Phosphorylation of histone H4 at serine 1 (H4S1Ph) is increased during the S-phase and mitosis in HeLa cells, C. elegans, and Drosophila, as well as during spermatogenesis in mice.{54369,54370} MG-63 cells expressing a serine-to-alanine substitution at Ser1 in histone H4, which abolishes its phosphorylation, have reduced markers of autophagy. Cayman’s Histone H4S1Ph Monoclonal Antibody can be used for ELISA, immunocytochemistry (ICC), multiplex-based assays, and Western blot (WB) applications.  

 

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SKU: 32154 - 100 µg Category:

Description

Immunogen: Peptide corresponding to H4S1Ph • Host: Rabbit • Species Reactivity: (+) Vertebrates • Cross Reactivity: (+) H4S1Ph, H4S1Ph/R3Me1, H4S1Ph/R3Me2; (-) Unmodified histone H4, H2AS1Ph • Applications: ELISA, ICC, multiplex-based assays, WB

Synonyms: H4pS1|H4pSer1|Histone H4 (Phospho-Ser1)|Phospho-Histone H4 Serine 10|Phosphorylated Histone H4 Serine 1

Immunogen: Peptide corresponding to H4S1Ph

Formulation: 100 µg of protein A-affinity purified monoclonal antibody

Isotype: IgG

Applications: ELISA, ICC, multiplex-based assays, WB

Origin:

Stability: 365 days

Application|ELISA||Application|Immunocytochemistry||Application|Multiplex||Application|Western Blot||Product Type|Antibodies|Monoclonal Antibodies||Research Area|Cell Biology|Cell Cycle||Research Area|Cell Biology|Endomembrane System & Vesicular Trafficking|Autophagy||Research Area|Endocrinology & Metabolism|Reproductive Biology||Research Area|Epigenetics, Transcription, & Translation|Histones/Histone Peptides|Phosphorylated||Research Area|Epigenetics, Transcription, & Translation|Writers|Phosphorylation

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