Immunogen: Peptide corresponding to H3K9Me3 • Host: Rabbit • Species Reactivity: (+) Vertebrates • Cross Reactivity: (+) H3K9Me3; (-) Unmodified H3K9

Histone H3K9Me3 Monoclonal Antibody – 100 µg

Brand:
Cayman
Storage:

Histone H3 is a nuclear protein and a component of the nucleosome core, a basic unit of chromatin, that is essential for organizing genomic DNA in eukaryotic nuclei.{57056} It is a globular protein that contains an unstructured N-terminal tail that extends outside of the nucleosome core and is subject to various post-translational modifications (PTMs), including methylation, phosphorylation, acetylation, and citrullination.{57056,53978} Trimethylation of histone H3 at lysine 9 (H3K9Me3) occludes DNA binding by transcription factors and is associated with gene repression.{42743} H3K9Me3 is also a binding target of the heterochromatin protein 1 (HP1) family proteins CBX1, CBX3, and CBX5.{20874} It is recognized by the plant homeodomain (PHD) fingers of chromodomain helicase DNA binding protein 4 (CHD4), a member of the NuRD deacetylase complex that is upregulated in a variety of cancers and implicated in the DNA damage response.{45178} Cayman’s Histone H3K9Me3 Monoclonal Antibody can be used for ELISA, multiplex-based assays, and Western blot (WB) applications.  

 

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SKU: 32138 - 100 µg Category:

Description

Immunogen: Peptide corresponding to H3K9Me3 • Host: Rabbit • Species Reactivity: (+) Vertebrates • Cross Reactivity: (+) H3K9Me3; (-) Unmodified H3K9, H3K9Me1, H3K9Me2, H3K4Me1, H3K4Me2, H3K4Me3, H3K27Me1, H3K27Me2, H3K27Me3, H3K36Me1, H3K36Me2, H3K36Me3, H4K20Me1, H4K20Me2, H4K20Me3 • Applications: ELISA, multiplex-based assays, WB

Synonyms: Trimethylated Histone H3 Lysine 9

Immunogen: Peptide corresponding to H3K9Me3

Formulation: 100 µg of protein A-affinity purified antibody

Isotype: IgG

Applications: ELISA, multiplex-based assays, WB

Origin:

Stability: 365 days

Application|ELISA||Application|Multiplex||Application|Western Blot||Product Type|Antibodies|Monoclonal Antibodies||Research Area|Epigenetics, Transcription, & Translation|Erasers|Histone Deacetylation||Research Area|Epigenetics, Transcription, & Translation|Erasers|Histone Demethylation||Research Area|Epigenetics, Transcription, & Translation|Histones/Histone Peptides|Methylated||Research Area|Epigenetics, Transcription, & Translation|Readers|Chromodomains||Research Area|Epigenetics, Transcription, & Translation|Readers|PHD Domains||Research Area|Epigenetics, Transcription, & Translation|Writers|Histone Methylation

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