Immunogen: A peptide corresponding to histone H3K36M mutant • Host: Rabbit • Cross Reactivity: (-) Wild-type histone H3 • Species Reactivity: (+) Histone H3K36M mutant • Applications: ELISA

Histone H3K36M Monoclonal Antibody – 400 µl

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Cayman
Storage:

Histone H3 undergoes many modifications including acetylation, methylation, and phosphorylation that are important for regulation of gene transcription. Lysine 36 of histone 3 (H3K36) has functionally relevant acetylation and methylation states with roles in transcriptional activation. More than 90% of chondroblastomas contain a heterozygous mutation, replacing H3K36 with methionine 36 (H3K36M) in the histone H3 variant H3.3.{32234} This antibody reacts to the H3K36M mutant and does not detect wild-type histone H3.  

 

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SKU: 31547 - 400 µl Category:

Description

Immunogen: A peptide corresponding to histone H3K36M mutant • Host: Rabbit • Cross Reactivity: (-) Wild-type histone H3 • Species Reactivity: (+) Histone H3K36M mutant • Applications: ELISA, IHC, WB • A probe for immunochemical detection of the H3K36M mutant

Synonyms:

Immunogen: A peptide corresponding to histone H3K36M mutant

Formulation: 100 or 400 µl of protein A-affinity purified monoclonal antibody

Isotype: IgG

Applications: ELISA, IHC, WB

Origin:

Stability: 365 days

Application|ELISA||Application|Immunohistochemistry||Application|Western Blot||Product Type|Antibodies|Monoclonal Antibodies||Research Area|Epigenetics, Transcription, & Translation|Histones/Histone Peptides

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