Antigen: synthetic peptide corresponding to amino acids 2-17 of human HDAC3 • Host: rabbit • Cross Reactivity: (+) human HDAC3 • Application(s): WB

HDAC3 Polyclonal Antibody – 1 ea

Brand:
Cayman
Storage:

Histone deacetylase (HDAC) and histone acetyltransferase (HAT) are enzymes that regulate transcription by selectively deacetylating or acetylating the ε-amino groups of lysines located near the amino termini of core histone proteins.{17241} Eleven members of HDAC family have been identified in the past several years.{17242,17240} These HDAC family members are divided into two classes, I and II. HDAC3 is a Class I HDAC which is related to the yeast HDAC Rpd3.{14468} It is primarily localized to the nucleus with ubiquitous distribution throughout human cell lines and tissues. By modifying chromatin structure and other non-histone proteins, HDACs play important roles in controlling complex biological events, including cell development, differentiation, programmed cell death, angiogenesis, and inflammation. Considering these major roles, it is conceivable that dysregulation of HDACs and subsequent imbalance of acetylation and deacetylation may be involved in the pathogenesis of various diseases, including cancer and inflammatory diseases.{14468}  

 

Available on backorder

Add to quotes
SKU: 13493 - 1 ea Category:

Description

Antigen: synthetic peptide corresponding to amino acids 2-17 of human HDAC3 • Host: rabbit • Cross Reactivity: (+) human HDAC3 • Application(s): WB, IP, and ChIP • HDAC3 is a class I HDAC that plays an important role in cell development, differentiation, programmed cell death, angiogenesis, and inflammation.

Synonyms: Histone Deacetylase 3

Immunogen: synthetic peptide corresponding to amino acids 2-17 of human HDAC3

Formulation: 100 µg of protein G-purified IgG in 200 µl PBS containing 0.02% sodium azide

Isotype:

Applications: WB, IP, and ChIP

Origin: Animal/Rabbit

Stability: 365 days

Application|Immunoprecipitation||Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Epigenetics, Transcription, & Translation|Erasers|Histone Deacetylation

Related products