Antigen: human GPX4 amino acids 81-93 (TQLVDLHARYAEC) · Host: rabbit · Cross Reactivity: (+) mouse

GPX4 Polyclonal Antibody – 1 ea

Brand:
Cayman
Storage:

Phospholipid hydroperoxide glutathione peroxidase (GPX4 or PhGPx) is one of four characterized selenium-dependent glutathione peroxidases.{7195} GPX4 is found primarily in the testis where it functions both to protect membrane phospholipids from oxidation in spermatids and as an insoluble structural protein in mature spermatozoa.{7195,7197} Three different post-translational forms of GPX4 have been characterized: mitochondrial, non-mitochondrial, and sperm nuclei specific selenoprotein (SnGPx).{12359} These monomeric GPX4 types migrate to 23, 20, and 34 kDa respectively.{7197,12359,12361,12360} GPX4 also forms a 69 kDa homotetramer.{12360} Cayman Chemical’s GPX4 polyclonal antibody can be used for western blot analysis of GPX4 on samples from mouse, rat, and pig, detecting both 20 kDa and 69 kDa bands. Sequence homology of the peptide antigen with that from other species indicates that the antibody is also expected to work on samples from human, bovine, canine, and chicken. Other applications for use of this antibody have not yet been tested.  

 

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SKU: 10005258 - 1 ea Category:

Description

Antigen: human GPX4 amino acids 81-93 (TQLVDLHARYAEC) · Host: rabbit · Cross Reactivity: (+) mouse, rat, and porcine GPX4 · Application: WB, IHC

Synonyms: Glutathione Peroxidase 4|PhGPx

Immunogen: Peptide from an internal region of human GPX4

Formulation: 500 μl of peptide affinity-purified antibody

Isotype:

Applications: IHC, WB

Origin: Animal/Rabbit

Stability: 365 days

Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Cell Biology|Cell Death|Ferroptosis||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen|Gluthathione Peroxidase

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