Immunogen: A synthetic peptide from the C-terminal region of human GPR17 • Host: rabbit • Cross Reactivity: (+) human

GPR17 (C-Term) Polyclonal Antibody – 1 ea

Brand:
Cayman
Storage:

GPR17 is a G protein-coupled receptor that has been identified as a dualistic receptor recognizing signals from two unrelated chemical families: nucleotides and CysLTs.{16467} The deorphanization of GPR17 supports the suggested crosstalk between nucleotides and CysLTs during inflammation and injury. mRNA transcripts encoding this transmembrane receptor are most strongly expressed in the brain, kidney, and heart. Upon ischemic injury, GPR17 is upregulated in these tissues and its inhibition has been shown to decrease ischemic damage. This finding suggests GPR17 as a pharmacological target of ischemic injury.{16467} Cayman’s peptide affinity-purified polyclonal antibody recognizes the C-terminal region of human GPR17. This protein exists in two isoforms, differing by 28 amino acids at the receptor N-terminus. The longer form of the protein consists of 367 amino acids with a calculated molecular weight of 41 kDa. The human and rat proteins share 89% amino acid identity.{16467} Post-translational modifications may explain the observed SDS-PAGE gel-migration to 57 kDa on immunoblot.  

 

Available on backorder

Add to quotes
SKU: 10136 - 1 ea Category:

Description

Immunogen: A synthetic peptide from the C-terminal region of human GPR17 • Host: rabbit • Cross Reactivity: (+) human, mouse, and rat • Application: IHC and WB

Synonyms: G Protein-Coupled Receptor 17

Immunogen: Synthetic peptide from the C-terminal region of human GPR17

Formulation: 500 µl of peptide affinity-purified antibody

Isotype:

Applications: IHC and WB

Origin: Animal/Rabbit

Stability: 730 days

Application|Flow Cytometry||Application|Immunocytochemistry||Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Cardiovascular System|Cardiovascular Diseases|Myocardial Infarction||Research Area|Immunology & Inflammation

Related products