Description
Ganglioside GD3 (Item No. 17481) is synthesized by the addition of two sialic acid residues to lactosylceramide and can serve as a precursor to the formation of more complex gangliosides by the action of glycosyl- and sialyltransferases.{31218} It induces apoptosis in HuT-78 cutaneous T cell lymphoma cells in a concentration-dependent manner and disrupts the mitochondrial membrane potential when used at a concentration of 200 μM.{5033} Expression of ganglioside GD3 in GD3-negative SK-MEL-28-N1 malignant melanoma cells increases both cell proliferation and invasion in vitro.{28470} Ganglioside GD3-deficient adult mice exhibit progressive loss of the neural stem cell (NSC) pool and impaired neurogenesis.{37782} Ganglioside GD3 Monoclonal Antibody can be used for ELISA and TLC immunobloting. [Matreya, LLC. Catalog No. 1977]
Synonyms:
Immunogen: Purified ganglioside GD3 and complete Freund’s adjuvant
Formulation: A liquid
Isotype: IgG/IgM
Applications: ELISA and TLC immunoblotting
Origin:
Stability: 730 days
Application|ELISA||Product Type|Antibodies|Monoclonal Antibodies||Research Area|Cancer|Cell Death|Apoptosis||Research Area|Cancer|Cell Migration & Metastasis||Research Area|Cell Biology|Mitochondrial Biology||Research Area|Lipid Biochemistry|Sphingolipids||Research Area|Neuroscience
