Immunogen: peptide from the internal region of human GPR43 • Host: rabbit • Cross Reactivity: (+) human GPR43 • Application(s): FC

FFAR2 (GPR43) (Internal) Polyclonal Antibody – 1 ea

Brand:
Cayman
Storage:

GPR43 is a G protein-coupled receptor activated by short chain fatty acids (SCFAs).{25541,25605,25606} Several SCFAs have the potential to bind and activate GPR43, including acetate, formate, propionate, and butyrate.{25605} GPR43 couples through the Pertussis toxin-sensitive Gi/o and the pertussis toxin-insensitive Gq protein families and its expression has been described in enteroendocrine cells and neutrophils.{25606,25605} The activation of GPR43 induces an increase in intracellular Ca2+, ERK1/2 activation, and a decrease in intracellular cAMP.{25606,25605,25541} Activation of GPR43 may be involved in intestinal inflammation. The predicted size of GPR43 is 37 kDa. Cayman’s GPR43 (Internal) Polyclonal Antibody detects a 37 kDa band in cell lysates.  

 

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SKU: 15727 - 1 ea Category:

Description

Immunogen: peptide from the internal region of human GPR43 • Host: rabbit • Cross Reactivity: (+) human GPR43 • Application(s): FC, IF, and WB

Synonyms: Free Fatty Acid Receptor 2|G Protein-Coupled Receptor 43

Immunogen: peptide from the internal region of human GPR43

Formulation: Peptide affinity-purified IgG lyophilized from TBS, pH 7.4, containing 5 mg/ml BSA

Isotype:

Applications: FC, IF, and WB

Origin:

Stability: 730 days

Application|Flow Cytometry||Application|Immunofluorescence||Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Cell Biology|Cell Signaling|ERK/MAPK Signaling||Research Area|Immunology & Inflammation|Innate Immunity||Research Area|Lipid Biochemistry|Fatty Acids

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