Efferocytosis Assay Kit – 1 ea

Brand:
Cayman
Storage:
-20

Efferocytosis is a specialized form of phagocytosis in which macrophages and other phagocytic cells clear dead and dying cells to promote homeostasis, embryonic development, regulation of the immune system and the resolution of inflammation.{35342} Efficient clearance of cells is essential for the removal of the nearly 1 million cells per second undergoing apoptosis in a human adult.{35343} Efferocytic removal of apoptotic cells before they become necrotic and release their contents can prevent an immune response to these non-pathogenic antigens.  

 

Available on backorder

SKU: 601770 - 1 ea Category:

Description

Cayman’s Efferocytosis Assay Kit employs CytoTell™ Blue to visualize effector (phagocytic) cells, CFSE to visualize bait (apoptotic) cells and staurosporine, a protein kinase C inhibitor, to induce apoptosis. The Efferocytosis Assay Kit is a convenient tool to study modulators of efferocytosis, apoptosis, pro-resolving mediators and cross-presentation. The reagents provided in this kit are sufficient to stain 5 x 107 effector cells and 2 x 108 bait cells.


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Application|Cell-Based Assay||Application|Flow Cytometry||Product Type|Assay Kits|Cell-Based Assays||Research Area|Immunology & Inflammation|Innate Immunity|Phagocytosis